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Conserved domains on  [gi|32967305|ref|NP_872282|]
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ubiquinone biosynthesis monooxygenase COQ6, mitochondrial isoform a [Homo sapiens]

Protein Classification

ubiquinone biosynthesis monooxygenase COQ6( domain architecture ID 10797688)

mitochondrial ubiquinone biosynthesis monooxygenase COQ6 catalyzes the hydroxylation of 3-hexaprenyl-4-hydroxybenzoic acid (HHB) to 3-hexaprenyl-4,5-dihydroxybenzoic acid (DHHB)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 48-463 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


:

Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 668.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305    48 AAMACALGYDIHFHDKKILLLEAG--PKK---VLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWD 122
Cdd:TIGR01989  13 LALAAALGNNPLTKDLKVLLLDAVdnPKLksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   123 ACSEALIMFDKDN-LDDMGYIVENDVIMHALTKQLEAV-SDRVTVLYRSKAIRYTWPCPFPmADSSPWVHITLGDGSTFQ 200
Cdd:TIGR01989  93 GCSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSKYP-NDNSNWVHITLSDGQVLY 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   201 TKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAE 280
Cdd:TIGR01989 172 TKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALR 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   281 LVSMDEEKFVDAVNSAF---WSDADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYV 357
Cdd:TIGR01989 252 LLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYV 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   358 RPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTS 437
Cdd:TIGR01989 332 TKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATD 411

                         410       420
                  ....*....|....*....|....*.
gi 32967305   438 ASPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:TIGR01989 412 FPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 48-463 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 668.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305    48 AAMACALGYDIHFHDKKILLLEAG--PKK---VLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWD 122
Cdd:TIGR01989  13 LALAAALGNNPLTKDLKVLLLDAVdnPKLksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   123 ACSEALIMFDKDN-LDDMGYIVENDVIMHALTKQLEAV-SDRVTVLYRSKAIRYTWPCPFPmADSSPWVHITLGDGSTFQ 200
Cdd:TIGR01989  93 GCSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSKYP-NDNSNWVHITLSDGQVLY 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   201 TKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAE 280
Cdd:TIGR01989 172 TKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALR 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   281 LVSMDEEKFVDAVNSAF---WSDADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYV 357
Cdd:TIGR01989 252 LLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYV 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   358 RPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTS 437
Cdd:TIGR01989 332 TKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATD 411

                         410       420
                  ....*....|....*....|....*.
gi 32967305   438 ASPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:TIGR01989 412 FPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 77-466 3.63e-74

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 238.90  E-value: 3.63e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   77 EKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGYIVENDVIMHALtk 154
Cdd:PRK08850  40 EALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPDLGHIVENRVIQLAL-- 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  155 qLEAVS--DRVTVLY--RSKAIRYtwpcpfpmADSSPWvhITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQS 230
Cdd:PRK08850 118 -LEQVQkqDNVTLLMpaRCQSIAV--------GESEAW--LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHS 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  231 AVVATLHLSEaTENNVAWQRFLPSGPIALLPLSDT-LSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFwsDADhtdfidt 309
Cdd:PRK08850 187 ALVANVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTAEF--DNR------- 256

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  310 agamlqyavslLKPTKVsarqlppsvarvdAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSL 389
Cdd:PRK08850 257 -----------LGLCEV-------------VGERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASL 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 32967305  390 AHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK08850 313 AQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 75-459 1.33e-40

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 148.16  E-value: 1.33e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  75 VLEKLSETYSN-RVSSISPGSATLLSSFGAWDHICnMRYRAFRRMQVWDACS-EALIMFD-KDNLDDMGYIVENDVIMHA 151
Cdd:COG0654  31 VVERAPPPRPDgRGIALSPRSLELLRRLGLWDRLL-ARGAPIRGIRVRDGSDgRVLARFDaAETGLPAGLVVPRADLERA 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 152 LTKQLEAvsDRVTVLYRSKAIRYTwpcpfPMADSspwVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSA 231
Cdd:COG0654 110 LLEAARA--LGVELRFGTEVTGLE-----QDADG---VTVTLADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRA 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 232 VVATLHlseatennVAWQRFLpsgpiallplsdtlsslvwstshehaaelvsmdeekfvdavnsafwsdadhtdfidtag 311
Cdd:COG0654 180 LWAGVR--------TELRARL----------------------------------------------------------- 192

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 312 amlqyavsllkptkvsaRQLPPSVARV-DAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLA 390
Cdd:COG0654 193 -----------------AAAGPRLGELlELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALA 255

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 32967305 391 HHLStAAFNGKDLGSVshLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLK 459
Cdd:COG0654 256 WKLA-AALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 194-427 8.31e-12

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 66.19  E-value: 8.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   194 GDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLS------EATENNVAWQRFLPSGPIALLPL-SDTL 266
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWrSAGR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   267 SSLVWS-TSHEHAAElvsmDEEKFVDAVNSAFWSDADHTDFIDTagamlqyavsllKPTKVSArqlppsvarVDAKSRVl 345
Cdd:pfam01494 223 ERYYVQvPWDEEVEE----RPEEFTDEELKQRLRSIVGIDLALV------------EILWKSI---------WGVASRV- 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   346 fplglghAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLStAAFNGKdlGSVSHLTGYETERQRHNTALLA 425
Cdd:pfam01494 277 -------ATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ--AGESLLDTYSAERLPVAWAVVD 346


                  ..
gi 32967305   426 AT 427
Cdd:pfam01494 347 FA 348
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 48-463 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 668.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305    48 AAMACALGYDIHFHDKKILLLEAG--PKK---VLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWD 122
Cdd:TIGR01989  13 LALAAALGNNPLTKDLKVLLLDAVdnPKLksrNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWD 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   123 ACSEALIMFDKDN-LDDMGYIVENDVIMHALTKQLEAV-SDRVTVLYRSKAIRYTWPCPFPmADSSPWVHITLGDGSTFQ 200
Cdd:TIGR01989  93 GCSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSKYP-NDNSNWVHITLSDGQVLY 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   201 TKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAE 280
Cdd:TIGR01989 172 TKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALR 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   281 LVSMDEEKFVDAVNSAF---WSDADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYV 357
Cdd:TIGR01989 252 LLSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYV 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   358 RPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTS 437
Cdd:TIGR01989 332 TKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATD 411

                         410       420
                  ....*....|....*....|....*.
gi 32967305   438 ASPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:TIGR01989 412 FPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 48-467 8.83e-156

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 447.04  E-value: 8.83e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305    48 AAMACALGYDIhfhdKKILLLEAGPKKVLEklSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEA 127
Cdd:TIGR01988  12 LALALALARSG----LKVALIEATPLPAPA--DPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDGGSFG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   128 LIMFDKD--NLDDMGYIVENDVIMHALtkqLEAVSDRVTVLYRSKAIRYTWPCpfpmadSSPWVHITLGDGSTFQTKLLI 205
Cdd:TIGR01988  86 ALRFDADeiGLEALGYVVENRVLQQAL---WERLQELPNVTLLCPARVVELPR------HSDHVELTLDDGQQLRARLLV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   206 GADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATeNNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMD 285
Cdd:TIGR01988 157 GADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPH-QGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLLALS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   286 EEKFVDAVNSAFWSDadhtdfidtAGAMlqyavsllkptkvsarqlppsvarVDAKSRVLFPLGLGHAAEYVRPRVALIG 365
Cdd:TIGR01988 236 DEEFLAELQRAFGSR---------LGAI------------------------TLVGERHAFPLSLTHAKRYVAPRLALIG 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   366 DAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLR 445
Cdd:TIGR01988 283 DAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLR 362

                         410       420
                  ....*....|....*....|..
gi 32967305   446 TWGLQATNAVSPLKEQIMAFAS 467
Cdd:TIGR01988 363 NLGLRLLNNLPPLKNFIARYAM 384
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 77-466 3.63e-74

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 238.90  E-value: 3.63e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   77 EKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGYIVENDVIMHALtk 154
Cdd:PRK08850  40 EALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPDLGHIVENRVIQLAL-- 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  155 qLEAVS--DRVTVLY--RSKAIRYtwpcpfpmADSSPWvhITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQS 230
Cdd:PRK08850 118 -LEQVQkqDNVTLLMpaRCQSIAV--------GESEAW--LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHS 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  231 AVVATLHLSEaTENNVAWQRFLPSGPIALLPLSDT-LSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFwsDADhtdfidt 309
Cdd:PRK08850 187 ALVANVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTAEF--DNR------- 256

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  310 agamlqyavslLKPTKVsarqlppsvarvdAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSL 389
Cdd:PRK08850 257 -----------LGLCEV-------------VGERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASL 312

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 32967305  390 AHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK08850 313 AQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
PRK07364 PRK07364
FAD-dependent hydroxylase;
64-459 1.84e-70

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 229.52  E-value: 1.84e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   64 KILLLEAGPKKVLEKLSETYSnrvssISPGSATLLSSFGAWDHICNmRYRAFRRMQVWDACSEALIMFDKDNL--DDMGY 141
Cdd:PRK07364  43 RIALIEAQPAEAAAAKGQAYA-----LSLLSARIFEGIGVWEKILP-QIGKFRQIRLSDADYPGVVKFQPTDLgtEALGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  142 IVENDVIMHALTKQLEAVsDRVTVLYRSKAIRYTWpcpfpmadSSPWVHITL---GDGSTFQTKLLIGADGHNSGVRQAV 218
Cdd:PRK07364 117 VGEHQVLLEALQEFLQSC-PNITWLCPAEVVSVEY--------QQDAATVTLeieGKQQTLQSKLVVAADGARSPIRQAA 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  219 GIQNVSWNYDQSAVVATLHLsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVdavnsafw 298
Cdd:PRK07364 188 GIKTKGWKYWQSCVTATVKH-EAPHNDIAYERFWPSGPFAILPLPGNRCQIVWTAPHAQAKALLALPEAEFL-------- 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  299 sdadhtdfidtagAMLQ--YAVSLLKPTKVSARQlppsvarvdaksrvLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAG 376
Cdd:PRK07364 259 -------------AELQqrYGDQLGKLELLGDRF--------------LFPVQLMQSDRYVQHRLALVGDAAHCCHPVGG 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  377 QGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVS 456
Cdd:PRK07364 312 QGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVP 391


                 ...
gi 32967305  457 PLK 459
Cdd:PRK07364 392 PLK 394
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
48-467 1.41e-66

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 218.67  E-value: 1.41e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   48 AAMACALGYDihfhDKKILLLEAGPkkVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVW-DAcsE 126
Cdd:PRK07608  18 ASLALALAQS----GLRVALLAPRA--PPRPADDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPVYDMRVFgDA--H 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  127 ALIMFD--KDNLDDMGYIVENDVIMHALTKQLeAVSDRVTVLyrskAIRYTwpcPFPMADSSpwVHITLGDGSTFQTKLL 204
Cdd:PRK07608  90 ARLHFSayQAGVPQLAWIVESSLIERALWAAL-RFQPNLTWF----PARAQ---GLEVDPDA--ATLTLADGQVLRADLV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  205 IGADGHNSGVRQAVGIQNVSWNYDQSAVVATLhLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSM 284
Cdd:PRK07608 160 VGADGAHSWVRSQAGIKAERRPYRQTGVVANF-KAERPHRGTAYQWFRDDGILALLPLPDGHVSMVWSARTAHADELLAL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  285 DEEKFVDAVNSAfwsdADHtdfidTAGAMlqyavsllkptkvsaRQLPPSVArvdaksrvlFPLGLGHAAEYVRPRVALI 364
Cdd:PRK07608 239 SPEALAARVERA----SGG-----RLGRL---------------ECVTPAAG---------FPLRLQRVDRLVAPRVALV 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  365 GDAAHRVHPLAGQGVNMGFGDISSLAHHL-STAAFngKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVL 443
Cdd:PRK07608 286 GDAAHLIHPLAGQGMNLGLRDVAALADVLaGREPF--RDLGDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARW 363

                        410       420
                 ....*....|....*....|....
gi 32967305  444 LRTWGLQATNAVSPLKEQIMAFAS 467
Cdd:PRK07608 364 LRNAGMALVGALPLVKRWLVRHAL 387
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 65-459 7.68e-65

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 214.69  E-value: 7.68e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   65 ILLLEAGPKKVLE-KLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGY 141
Cdd:PRK05714  28 VLLLDGGPLSVKPfDPQAPFEPRVSALSAASQRILERLGAWDGIAARRASPYSEMQVWDGSGTGQIHFSAASVhaEVLGH 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  142 IVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTwpcpfpmadSSPWVhITLGDGSTFQTKLLIGADGHNSGVRQAVGIQ 221
Cdd:PRK05714 108 IVENRVVQDALLERLHDSDIGLLANARLEQMRRS---------GDDWL-LTLADGRQLRAPLVVAADGANSAVRRLAGCA 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  222 NVSWNYDQSAVVATLHLSEAtENNVAWQRFLPSGPIALLPLSDT----LSSLVWSTSHEHAAELVSMDEEKFVDAVNSAF 297
Cdd:PRK05714 178 TREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLERDgdehWCSIVWSTTPEEAERLMALDDDAFCAALERAF 256

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  298 WSdadhtdfidTAGAMLQyavsllkptkvsarqlppsvarvdAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQ 377
Cdd:PRK05714 257 EG---------RLGEVLS------------------------ADPRLCVPLRQRHAKRYVEPGLALIGDAAHTIHPLAGQ 303

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  378 GVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSP 457
Cdd:PRK05714 304 GVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKLVDQMPE 383


                 ..
gi 32967305  458 LK 459
Cdd:PRK05714 384 AK 385
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 86-466 1.29e-64

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 213.31  E-value: 1.29e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   86 RVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSeALIMFDKD--NLDDMGYIVENDVIMHALTKQLEAVSDrV 163
Cdd:PRK08020  51 RISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWET-AHVVFDAAelKLPELGYMVENRVLQLALWQALEAHPN-V 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  164 TVLyrskairytwpCPFPMADSSP----WvHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHlS 239
Cdd:PRK08020 129 TLR-----------CPASLQALQRdddgW-ELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVK-C 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  240 EATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFwsdadhtdfidtagamlqyavs 319
Cdd:PRK08020 196 ENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHF---------------------- 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  320 llkPTKVSArqlppsVARVDAKSrvlFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFN 399
Cdd:PRK08020 254 ---PARLGA------VTPVAAGA---FPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSY 321

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 32967305  400 GKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFA 466
Cdd:PRK08020 322 GEAWASEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYA 388
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 63-466 1.65e-63

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 210.40  E-value: 1.65e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   63 KKILLLEAGPKKVLEKlSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDAcSEALIMFDKD--NLDDMG 140
Cdd:PRK08849  27 RSVAVIEGGEPKAFEP-SQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKRLETWEH-PECRTRFHSDelNLDQLG 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  141 YIVENDVIMHALTKQLEAVsDRVTVLyrskairytwpCPFPMAD---SSPWVHITLGDGSTFQTKLLIGADGHNSGVRQA 217
Cdd:PRK08849 105 YIVENRLIQLGLWQQFAQY-PNLTLM-----------CPEKLADlefSAEGNRVTLESGAEIEAKWVIGADGANSQVRQL 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  218 VGIQNVSWNYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAF 297
Cdd:PRK08849 173 AGIGITAWDYRQHCMLINVE-TEQPQQDITWQQFTPSGPRSFLPLCGNQGSLVWYDSPKRIKQLSAMNPEQLRSEILRHF 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  298 wsDADHTDFidtagAMLQYAVsllkptkvsarqlppsvarvdaksrvlFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQ 377
Cdd:PRK08849 252 --PAELGEI-----KVLQHGS---------------------------FPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQ 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  378 GVNMGFGDISSLAHhlstaAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSP 457
Cdd:PRK08849 298 GVNLGFKDVDVLLA-----ETEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGP 372


                 ....*....
gi 32967305  458 LKEQIMAFA 466
Cdd:PRK08849 373 LKTQVLKYA 381
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 64-462 1.55e-62

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 207.94  E-value: 1.55e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305    64 KILLLEAgpkKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNmRYRAFRRMQVWDACSEALIMFDKD--NLDDMGY 141
Cdd:TIGR01984  25 KIALIEA---NSPSAAQPGFDARSLALSYGSKQILEKLGLWPKLAP-FATPILDIHVSDQGHFGATHLRASefGLPALGY 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   142 IVENDVIMHALTKQLeavsDRVTVLyrskairyTWPCPFPMADSSP---WVHITLGDGSTFQTKLLIGADGHNSGVRQAV 218
Cdd:TIGR01984 101 VVELADLGQALLSRL----ALLTNI--------QLYCPARYKEIIRnqdYVRVTLDNGQQLRAKLLIAADGANSKVRELL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   219 GIQNVSWNYDQSAVVATLHLSEATENnVAWQRFLPSGPIALLPLSD-TLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAF 297
Cdd:TIGR01984 169 SIPTEEHDYNQTALIANIRHEQPHQG-CAFERFTPHGPLALLPLKDnYRSSLVWCLPSKQADTIANLPDAEFLAELQQAF 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   298 WSDAdhtdfidtaGAMLQyavsllkptkVSARQLppsvarvdaksrvlFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQ 377
Cdd:TIGR01984 248 GWRL---------GKITQ----------VGERKT--------------YPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQ 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   378 GVNMGFGDISSLAHHLSTAAfngKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSP 457
Cdd:TIGR01984 295 GFNLGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPP 371


                  ....*
gi 32967305   458 LKEQI 462
Cdd:TIGR01984 372 LKKRL 376
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
62-460 1.24e-61

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 205.98  E-value: 1.24e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   62 DKKILLLEAGPKKVLEKlsetySNRVSSISPGSATLLSSFGAWDHICNmRYRAFRRMQVWDACSE-----ALIMFDKDNL 136
Cdd:PRK07333  26 HLPVTVVDAAPAGAWSR-----DPRASAIAAAARRMLEALGVWDEIAP-EAQPITDMVITDSRTSdpvrpVFLTFEGEVE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  137 DD--MGYIVENDVIMHALTKQLEAVSdrVTVLYRSKAIRYTwpcpfpmADSSPwVHITLGDGSTFQTKLLIGADGHNSGV 214
Cdd:PRK07333 100 PGepFAHMVENRVLINALRKRAEALG--IDLREATSVTDFE-------TRDEG-VTVTLSDGSVLEARLLVAADGARSKL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  215 RQAVGIQNVSWNYDQSAVVATL-HlsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAV 293
Cdd:PRK07333 170 RELAGIKTVGWDYGQSGIVCTVeH--ERPHGGRAEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAEL 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  294 NSAFWsdadhtdfidtagamlqyavslLKPTKVsarqlppsvaRVDAKSRVlFPLGLGHAAEYVRPRVALIGDAAHRVHP 373
Cdd:PRK07333 248 EQRFG----------------------HRLGEL----------KVLGKRRA-FPLGLTLARSFVAPRFALVGDAAHGIHP 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  374 LAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATN 453
Cdd:PRK07333 295 IAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVD 374


                 ....*..
gi 32967305  454 AVSPLKE 460
Cdd:PRK07333 375 RLPKLKS 381
PRK08013 PRK08013
oxidoreductase; Provisional
 75-463 6.29e-59

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 198.73  E-value: 6.29e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   75 VLEK-------LSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDN--LDDMGYIVEN 145
Cdd:PRK08013  31 VLEQrvpeplaADAPPALRVSAINAASEKLLTRLGVWQDILARRASCYHGMEVWDKDSFGRIAFDDQSmgYSHLGHIIEN 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  146 DVIMHALTKQLEAVSDrVTVLYRSKAIRYTWpcpfpmadSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSW 225
Cdd:PRK08013 111 SVIHYALWQKAQQSSD-ITLLAPAELQQVAW--------GENEAFLTLKDGSMLTARLVVGADGANSWLRNKADIPLTFW 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  226 NYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSD-TLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFwsdaDHt 304
Cdd:PRK08013 182 DYQHHALVATIR-TEEPHDAVARQVFHGDGILAFLPLSDpHLCSIVWSLSPEEAQRMQQAPEEEFNRALAIAF----DN- 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  305 dfidtagamlqyavSLLKPTKVSARQlppsvarvdaksrvLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFG 384
Cdd:PRK08013 256 --------------RLGLCELESERQ--------------VFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFM 307

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 32967305  385 DISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:PRK08013 308 DAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKPQLI 386
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
86-458 7.75e-56

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 190.46  E-value: 7.75e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   86 RVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEALIMFDKDNL--DDMGYIVENDVIMHALTKQLEAVSDRV 163
Cdd:PRK08773  51 RVYAFAADNAALLDRLGVWPAVRAARAQPYRRMRVWDAGGGGELGFDADTLgrEQLGWIVENDLLVDRLWAALHAAGVQL 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  164 TVLYRSKAIRytwpcpfPMADSspwVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVA---TLHLSE 240
Cdd:PRK08773 131 HCPARVVALE-------QDADR---VRLRLDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAfvdTEHPHQ 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  241 ATennvAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFwsdadhtdfidtaGAMLQyAVSL 320
Cdd:PRK08773 201 AT----AWQRFLPTGPLALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQAF-------------AARLG-EVRV 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  321 LKPtkvsarqlppsvarvdaksRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNG 400
Cdd:PRK08773 263 ASP-------------------RTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARR 323

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 32967305  401 KDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPL 458
Cdd:PRK08773 324 ADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPL 381
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 83-459 2.16e-54

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 186.60  E-value: 2.16e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   83 YSNRVSSISPGSATLLSSFGAWDHIcNMRYRAFRRMQVWDACSEALIMFDKD--NLDDMGYIVENdvimHALTKQLEAVS 160
Cdd:PRK05732  48 FDARAIALAAGTCQQLARLGVWQAL-ADCATPITHIHVSDRGHAGFVRLDAEdyGVPALGYVVEL----HDVGQRLFALL 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  161 DrvtvlyrsKAIRYTWPCPFPMADSSP---WVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLH 237
Cdd:PRK05732 123 D--------KAPGVTLHCPARVANVERtqgSVRVTLDDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIANVT 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  238 LSEAtENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAF-WSdadhtdfidtAGAMlqy 316
Cdd:PRK05732 195 TSEA-HQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWSDAQFLAELQQAFgWR----------LGRI--- 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  317 avsllkpTKVSARQlppsvarvdaksrvLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTA 396
Cdd:PRK05732 261 -------THAGKRS--------------AYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQA 319

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32967305  397 AFNGKDLGSVSHLTGYETERQ--RHNTalLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLK 459
Cdd:PRK05732 320 LARGEDIGDYAVLQRYQQRRQqdREAT--IGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPAR 382
PRK09126 PRK09126
FAD-dependent hydroxylase;
49-462 7.18e-43

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 155.87  E-value: 7.18e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   49 AMACALGYdihfHDKKILLLEAGPKKVLEklSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQVWDACSEAL 128
Cdd:PRK09126  17 SFARSLAG----SGLKVTLIERQPLAALA--DPAFDGREIALTHASREILQRLGAWDRIPEDEISPLRDAKVLNGRSPFA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  129 IMFDKDN--LDDMGYIVENDVIMHALtkqLEAVS--DRVTVL--YRSKAIRytwpcpfpmaDSSPWVHITLGDGSTFQTK 202
Cdd:PRK09126  91 LTFDARGrgADALGYLVPNHLIRRAA---YEAVSqqDGIELLtgTRVTAVR----------TDDDGAQVTLANGRRLTAR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  203 LLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELV 282
Cdd:PRK09126 158 LLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMR-HELPHHHTAWEWFGYGQTLALLPLNGHLSSLVLTLPPDQIEALL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  283 SMDEEKFVDAVNSAFWsdadhtdfiDTAGAMlqyavsllkpTKVSARQLPPSVARvdaksrvlfplglgHAAEYVRPRVA 362
Cdd:PRK09126 237 ALDPEAFAAEVTARFK---------GRLGAM----------RLVSSRHAYPLVAV--------------YAHRFVAKRFA 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  363 LIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHNTALLAATDLLKRLYSTSASPLV 442
Cdd:PRK09126 284 LIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLLERYERKHRLATRPLYHATNAIAALYTDDRPPAR 363

                        410       420
                 ....*....|....*....|
gi 32967305  443 LLRTWGLQATNAVSPLKEQI 462
Cdd:PRK09126 364 LLRRAVLRAANRFPPLKQAI 383
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 75-459 1.33e-40

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 148.16  E-value: 1.33e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  75 VLEKLSETYSN-RVSSISPGSATLLSSFGAWDHICnMRYRAFRRMQVWDACS-EALIMFD-KDNLDDMGYIVENDVIMHA 151
Cdd:COG0654  31 VVERAPPPRPDgRGIALSPRSLELLRRLGLWDRLL-ARGAPIRGIRVRDGSDgRVLARFDaAETGLPAGLVVPRADLERA 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 152 LTKQLEAvsDRVTVLYRSKAIRYTwpcpfPMADSspwVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSA 231
Cdd:COG0654 110 LLEAARA--LGVELRFGTEVTGLE-----QDADG---VTVTLADGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRA 179

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 232 VVATLHlseatennVAWQRFLpsgpiallplsdtlsslvwstshehaaelvsmdeekfvdavnsafwsdadhtdfidtag 311
Cdd:COG0654 180 LWAGVR--------TELRARL----------------------------------------------------------- 192

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 312 amlqyavsllkptkvsaRQLPPSVARV-DAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLA 390
Cdd:COG0654 193 -----------------AAAGPRLGELlELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALA 255

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 32967305 391 HHLStAAFNGKDLGSVshLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLK 459
Cdd:COG0654 256 WKLA-AALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
85-463 2.90e-38

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 143.12  E-value: 2.90e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   85 NRVSSISPGSATLLSSFGAWDHiCNMRYRAFRRMQVWDACSEAL----IMFDKD--NLDDMGYIVENDVIMHALTKQLEA 158
Cdd:PRK07494  45 LRTTALLGPSIRFLERLGLWAR-LAPHAAPLQSMRIVDATGRLIrapeVRFRAAeiGEDAFGYNIPNWLLNRALEARVAE 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  159 VS--DRVTVLYRSKAIRytwpcpfpmADSspwVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVV-AT 235
Cdd:PRK07494 124 LPniTRFGDEAESVRPR---------EDE---VTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVlNF 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  236 LHlsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFvdavnsafwsdadhtdfidtAGAMLQ 315
Cdd:PRK07494 192 TH--SRPHQNVSTEFHTEGGPFTQVPLPGRRSSLVWVVRPAEAERLLALSDAAL--------------------SAAIEE 249

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  316 YAVSLLKPTKVSARqlppsvarvdaksRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAhhlST 395
Cdd:PRK07494 250 RMQSMLGKLTLEPG-------------RQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLV---EI 313

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  396 AAFNGKDLGSVSHLTGYetERQRHNTALL--AATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIM 463
Cdd:PRK07494 314 VEDRPEDPGSAAVLAAY--DRARRPDILSrtASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
86-462 4.66e-33

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 129.04  E-value: 4.66e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   86 RVSSISPGSATLLSSFGAW-------DHI-CNMRYRAFRrmqvwdacseALIMFDKDNLDDMGYIVENDVIMHALTKQLE 157
Cdd:PRK06996  57 RAIALSHGSRVLLETLGAWpadatpiEHIhVSQRGHFGR----------TLIDRDDHDVPALGYVVRYGSLVAALARAVR 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  158 AVsdRVTVLYRSKAirytwPCPFPMADSSPWVHITLGDGSTFQTKLLIGADGH-NSGVRQAVGIQNVSWNYDQSAVVATL 236
Cdd:PRK06996 127 GT--PVRWLTSTTA-----HAPAQDADGVTLALGTPQGARTLRARIAVQAEGGlFHDQKADAGDSARRRDYGQTAIVGTV 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  237 HLSeATENNVAWQRFLPSGPIALLPLSDTLS---SLVWSTSHEHAAELVSMDEEKFVDAVNSAFWsdadhtdfiDTAGAM 313
Cdd:PRK06996 200 TVS-APRPGWAWERFTHEGPLALLPLGGPRQadyALVWCCAPDEAARRAALPDDAFLAELGAAFG---------TRMGRF 269

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  314 LQyavsllkptkvsarqlppsvarvdAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHL 393
Cdd:PRK06996 270 TR------------------------IAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADAL 325

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  394 STAAFNGKDLGSVShltgyetERQRHNTALLA-ATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQI 462
Cdd:PRK06996 326 SDHGATPLALATFA-------ARRALDRRVTIgATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHAL 388
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 86-466 7.34e-28

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 114.25  E-value: 7.34e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   86 RVSSISPGSATLLSSFGAWDHIcnmrYRAFRRMQ-VWDACSEALIMFDKDNLDD--MGYIVENdvimhaltkqleavSDR 162
Cdd:PRK06617  45 RTTALTPHSKNFLFSIDIWEEL----EKFVAEMQdIYVVDNKASEILDLRNDADavLGYVVKN--------------SDF 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  163 VTVLYrSKAIrytwpcpfpmadSSPWvhITLGDGSTFQ-------------------TKLLIGADGHNSGVRQAVGIQNV 223
Cdd:PRK06617 107 KKILL-SKIT------------NNPL--ITLIDNNQYQevishndysiikfddkqikCNLLIICDGANSKVRSHYFANEI 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  224 SWNYDQSAVVATLHlsEATENNVAWQRFLPSGPIALLPLSDTL-SSLVWSTSHEHAAELVSMDEEKfvdavnsafwsdad 302
Cdd:PRK06617 172 EKPYQTALTFNIKH--EKPHENCAMEHFLPLGPFALLPLKDQYaSSVIWSTSSDQAALIVNLPVEE-------------- 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  303 hTDFIdtagamlqyavsllkptkvSARQLPPSVARVDAKSRVL-FPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNM 381
Cdd:PRK06617 236 -VRFL-------------------TQRNAGNSLGKITIDSEISsFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQ 295

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  382 GFGDISSLAHHLSTaafNGKdlgsvshLTGYETERQRHNTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQ 461
Cdd:PRK06617 296 GIKDIEILSMIVSN---NGT-------LQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNL 365


                 ....*
gi 32967305  462 IMAFA 466
Cdd:PRK06617 366 ITSYA 370
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 194-427 8.31e-12

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 66.19  E-value: 8.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   194 GDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLS------EATENNVAWQRFLPSGPIALLPL-SDTL 266
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWrSAGR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   267 SSLVWS-TSHEHAAElvsmDEEKFVDAVNSAFWSDADHTDFIDTagamlqyavsllKPTKVSArqlppsvarVDAKSRVl 345
Cdd:pfam01494 223 ERYYVQvPWDEEVEE----RPEEFTDEELKQRLRSIVGIDLALV------------EILWKSI---------WGVASRV- 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305   346 fplglghAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLStAAFNGKdlGSVSHLTGYETERQRHNTALLA 425
Cdd:pfam01494 277 -------ATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ--AGESLLDTYSAERLPVAWAVVD 346


                  ..
gi 32967305   426 AT 427
Cdd:pfam01494 347 FA 348
PRK06834 PRK06834
hypothetical protein; Provisional
 189-385 3.39e-09

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 58.88  E-value: 3.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  189 VHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNV--------AWQRFLPSGPIALl 260
Cdd:PRK06834 133 VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWGVhrdalgihAFGRLEDEGPVRV- 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  261 plsdtlsslVWSTSHEHAAELVSMDEEKfvDAVNSAFWSDadhtdfidtagamlqYAVSllKPTKVS-----ARQlppsv 335
Cdd:PRK06834 212 ---------MVTEKQVGATGEPTLDDLR--EALIAVYGTD---------------YGIH--SPTWISrftdmARQ----- 258

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 32967305  336 arvdaksrvlfplglghAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGD 385
Cdd:PRK06834 259 -----------------AASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
PRK07045 PRK07045
putative monooxygenase; Reviewed
 191-446 1.13e-08

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 56.84  E-value: 1.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  191 ITLGDGSTFQTKLLIGADGHNSGVRQAV-GIQNVSWNYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSL 269
Cdd:PRK07045 144 VTLSDGERVAPTVLVGADGARSMIRDDVlRMPAERVPYATPMAFGTIALTDSVRECNRLYVDSNQGLAYFYPIGDQATRL 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  270 VWSTSHEHAAELVSMDEEKFVDAVNSAFWSDadhtdfiDTAGAMlqyavsllkptkvsarqlppsvARVDAKSRV-LFPL 348
Cdd:PRK07045 224 VVSFPADEMQGYLADTTRTKLLARLNEFVGD-------ESADAM----------------------AAIGAGTAFpLIPL 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  349 GLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVshLTGYETERQRHNTALLAATD 428
Cdd:PRK07045 275 GRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHLSGQIALADA--LERFERIRRPVNEAVISYGH 352

                        250
                 ....*....|....*...
gi 32967305  429 LLKRLYSTSASPLVLLRT 446
Cdd:PRK07045 353 ALATTYHDRAALVANFRS 370
PRK08244 PRK08244
monooxygenase;
197-465 3.66e-07

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 52.44  E-value: 3.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  197 STFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEATENNVAwQRFLPSGPIALLPLSDTLSSLVWSTSHE 276
Cdd:PRK08244 144 RTLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVL-SLCTREGGVMIVPLSGGIYRVLIIDPER 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  277 HAA---ELVSMDEEKfvdavnsafwsdadhTDFIDTAGAMLqyavSLLKPTKVSarqlppsvaRVDAKSRvlfplglgHA 353
Cdd:PRK08244 223 PQVpkdEPVTLEELK---------------TSLIRICGTDF----GLNDPVWMS---------RFGNATR--------QA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  354 AEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLStAAFNGKDLGSVshLTGYETERQRHNTALLAATDLLKRL 433
Cdd:PRK08244 267 ERYRSGRIFLAGDAAHIHFPAGGQGLNVGLQDAMNLGWKLA-AAIKGWAPDWL--LDSYHAERHPVGTALLRNTEVQTKL 343

                        250       260       270
                 ....*....|....*....|....*....|....
gi 32967305  434 YSTSASPLVLLRTWG--LQATNAVSPLKEQIMAF 465
Cdd:PRK08244 344 FDFTRPGLALRSMLSdlLGFPEVNRYLAGQISAL 377
PRK06184 PRK06184
hypothetical protein; Provisional
 194-417 2.32e-05

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 46.52  E-value: 2.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  194 GDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQS-AVVATLHLSEATENnvAWQRFLPS--GPIALLPLSDTlsslv 270
Cdd:PRK06184 150 AGEETVRARYLVGADGGRSFVRKALGIGFPGETLGIDrMLVADVSLTGLDRD--AWHQWPDGdmGMIALCPLPGT----- 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  271 wsTSHEHAAELvsmDEEKFVDAvnsafwSDADHTDFIDTAGAMLQYAVSllKPTKVSARQlpPSVARVDAksrvlfplgl 350
Cdd:PRK06184 223 --DLFQIQAPL---PPGGEPDL------SADGLTALLAERTGRTDIRLH--SVTWASAFR--MNARLADR---------- 277

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32967305  351 ghaaeYVRPRVALIGDAAHrVHPLAG-QGVNMGFGDisslahhlstaAFN-GKDLGSVSH------LTGYETERQ 417
Cdd:PRK06184 278 -----YRVGRVFLAGDAAH-VHPPAGgQGLNTSVQD-----------AYNlGWKLAAVLAgapealLDTYEEERR 335
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
75-418 6.02e-05

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 44.57  E-value: 6.02e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  75 VLEKLSE-TYSNRVSSISPGSATLLSSFGAWDHICnmryRAFRRMQVWdACSEALIMFDKDNldDMGYIVENDVIMHALT 153
Cdd:COG0644  21 LLEKGSFpGDKICGGGLLPRALEELEPLGLDEPLE----RPVRGARFY-SPGGKSVELPPGR--GGGYVVDRARFDRWLA 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 154 KQleAVSDRVTVLYRSKAIRYTWpcpfpmadSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGiqnvswnydqsavv 233
Cdd:COG0644  94 EQ--AEEAGAEVRTGTRVTDVLR--------DDGRVVVRTGDGEEIRADYVVDADGARSLLARKLG-------------- 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 234 ATLHLSEATENNVAWQrflpsgpiallplsdtlsslvwstshehaaELVSMDEEKFVDAVNSAFWSDADHTDFidtagam 313
Cdd:COG0644 150 LKRRSDEPQDYALAIK------------------------------EHWELPPLEGVDPGAVEFFFGEGAPGG------- 192

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305 314 lqYA-VSLLKPTKVSarqlppsvarvdaksrVLFPLGlGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFgdISslAHH 392
Cdd:COG0644 193 --YGwVFPLGDGRVS----------------VGIPLG-GPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAM--KS--GRL 249

                       330       340
                ....*....|....*....|....*...
gi 32967305 393 LSTAAFNGKDLGSVSH--LTGYETERQR 418
Cdd:COG0644 250 AAEAIAEALEGGDFSAeaLAEYERRLRE 277
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
353-447 6.27e-05

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 45.28  E-value: 6.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  353 AAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLStAAFNGK---DLgsvshLTGYETERQRHNTALLAATDL 429
Cdd:PRK06183 280 ADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDAANLAWKLA-AVLRGRagdAL-----LDTYEQERRPHARAMIDLAVR 353

                         90
                 ....*....|....*...
gi 32967305  430 LKRLYSTSASPLVLLRTW 447
Cdd:PRK06183 354 LGRVICPTDRLAAALRDA 371
PRK07236 PRK07236
hypothetical protein; Provisional
 189-425 1.71e-03

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 40.68  E-value: 1.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  189 VHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQN-------VSWNydqsAVVATLHLSEAT----ENNVAWQR------- 250
Cdd:PRK07236 131 VTARFADGRRETADLLVGADGGRSTVRAQLLPDVrptyagyVAWR----GLVDEAALPPEAraalRDRFTFQLgpgshil 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  251 -FLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMdeekfvdavnsafwsdadhtdFIDTAGAMLQYAVS--LLKPTKVS 327
Cdd:PRK07236 207 gYPVPGEDGSTEPGKRRYNWVWYRNAPAGEELDEL---------------------LTDRDGTRRPFSVPpgALRDDVLA 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  328 ------ARQLPPSVAR-VDAKSRVLFPLGLGHAAE-YVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAfn 399
Cdd:PRK07236 266 elrddaAELLAPVFAElVEATAQPFVQAIFDLEVPrMAFGRVALLGDAAFVARPHTAAGVAKAAADAVALAEALAAAA-- 343

                        250       260
                 ....*....|....*....|....*..
gi 32967305  400 gkdlGSV-SHLTGYETERQRHNTALLA 425
Cdd:PRK07236 344 ----GDIdAALAAWEAERLAVGAAIVA 366
PRK06185 PRK06185
FAD-dependent oxidoreductase;
358-417 4.40e-03

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 39.46  E-value: 4.40e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 32967305  358 RPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKdlGSVSHLTGYETERQ 417
Cdd:PRK06185 283 RPGLLCIGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGR--VSDRDLAAVQRRRE 340
PRK08294 PRK08294
phenol 2-monooxygenase; Provisional
 359-417 8.82e-03

phenol 2-monooxygenase; Provisional


Pssm-ID: 236223 [Multi-domain]  Cd Length: 634  Bit Score: 38.43  E-value: 8.82e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 32967305  359 PRVALIGDAAHRVHPLAGQGVNMGFGDisslahhlstaAFN-GKDLGSV-------SHLTGYETERQ 417
Cdd:PRK08294 340 PRVFIAGDACHTHSAKAGQGMNVSMQD-----------GFNlGWKLAAVlsgrsppELLHTYSAERQ 395
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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