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Conserved domains on  [gi|28274703|ref|NP_777561|]
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protein FAM9C [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cor1 super family cl04763
Cor1/Xlr/Xmr conserved region; Cor1 is a component of the chromosome core in the meiotic ...
 78-158 3.59e-06

Cor1/Xlr/Xmr conserved region; Cor1 is a component of the chromosome core in the meiotic prophase chromosomes. Xlr is a lymphoid cell specific protein. Xlm is abundantly transcribed in testis in a tissue-specific and developmentally regulated manner. The protein is located in the nuclei of spermatocytes, early in the prophase of the first meiotic division, and later becomes concentrated in the XY nuclear subregion where it is in particular associated with the axes of sex chromosomes.


The actual alignment was detected with superfamily member pfam04803:

Pssm-ID: 461436  Cd Length: 124  Bit Score: 43.76  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28274703    78 LAAKRKRIEKIAKA-CSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKeeqIKIFQEQQKRW 156
Cdd:pfam04803   3 LLAKRKRLETFTKAsLKSSNEKIEHVWKTQQEQRQKLNEEYSQQFLTLFQQWDTDVQKTKEQEEKL---SNLFQQQQKLF 79


                  ..
gi 28274703   157 QQ 158
Cdd:pfam04803  80 QQ 81
 
Name Accession Description Interval E-value
Cor1 pfam04803
Cor1/Xlr/Xmr conserved region; Cor1 is a component of the chromosome core in the meiotic ...
 78-158 3.59e-06

Cor1/Xlr/Xmr conserved region; Cor1 is a component of the chromosome core in the meiotic prophase chromosomes. Xlr is a lymphoid cell specific protein. Xlm is abundantly transcribed in testis in a tissue-specific and developmentally regulated manner. The protein is located in the nuclei of spermatocytes, early in the prophase of the first meiotic division, and later becomes concentrated in the XY nuclear subregion where it is in particular associated with the axes of sex chromosomes.


Pssm-ID: 461436  Cd Length: 124  Bit Score: 43.76  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28274703    78 LAAKRKRIEKIAKA-CSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKeeqIKIFQEQQKRW 156
Cdd:pfam04803   3 LLAKRKRLETFTKAsLKSSNEKIEHVWKTQQEQRQKLNEEYSQQFLTLFQQWDTDVQKTKEQEEKL---SNLFQQQQKLF 79


                  ..
gi 28274703   157 QQ 158
Cdd:pfam04803  80 QQ 81
 
Name Accession Description Interval E-value
Cor1 pfam04803
Cor1/Xlr/Xmr conserved region; Cor1 is a component of the chromosome core in the meiotic ...
 78-158 3.59e-06

Cor1/Xlr/Xmr conserved region; Cor1 is a component of the chromosome core in the meiotic prophase chromosomes. Xlr is a lymphoid cell specific protein. Xlm is abundantly transcribed in testis in a tissue-specific and developmentally regulated manner. The protein is located in the nuclei of spermatocytes, early in the prophase of the first meiotic division, and later becomes concentrated in the XY nuclear subregion where it is in particular associated with the axes of sex chromosomes.


Pssm-ID: 461436  Cd Length: 124  Bit Score: 43.76  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28274703    78 LAAKRKRIEKIAKA-CSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKeeqIKIFQEQQKRW 156
Cdd:pfam04803   3 LLAKRKRLETFTKAsLKSSNEKIEHVWKTQQEQRQKLNEEYSQQFLTLFQQWDTDVQKTKEQEEKL---SNLFQQQQKLF 79


                  ..
gi 28274703   157 QQ 158
Cdd:pfam04803  80 QQ 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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