NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|52856421|ref|NP_777553|]
View 

chromatin complexes subunit BAP18 isoform 2 [Homo sapiens]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10446569)

SANT/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.20.58.1880
Gene Ontology:  GO:0003677|GO:0006355|GO:0003700
PubMed:  8882580
SCOP:  4000317

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 41-77 7.80e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.64  E-value: 7.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 52856421    41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIK 77
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCK 39
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 41-77 7.80e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.64  E-value: 7.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 52856421    41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIK 77
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCK 39
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 41-77 1.24e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 35.24  E-value: 1.24e-03
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 52856421  41 KWTETEIEMLRAAVKRFG-DDLNHISCVIKERTVAQIK 77
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCR 38
 
Name Accession Description Interval E-value
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 41-77 7.80e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.64  E-value: 7.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 52856421    41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIK 77
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCK 39
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 41-77 1.24e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 35.24  E-value: 1.24e-03
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 52856421  41 KWTETEIEMLRAAVKRFG-DDLNHISCVIKERTVAQIK 77
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCR 38
Myb_DNA-bind_7 pfam15963
Myb DNA-binding like;
41-82 5.78e-03

Myb DNA-binding like;


Pssm-ID: 464956 [Multi-domain]  Cd Length: 85  Bit Score: 34.44  E-value: 5.78e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 52856421    41 KWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKATVKR 82
Cdd:pfam15963  10 RWSKEETELFYKALSMFGTDFSLIAQLFPGRTRRQIKLKFKR 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH