|
Name |
Accession |
Description |
Interval |
E-value |
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
19-335 |
2.97e-174 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 489.05 E-value: 2.97e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVGQDPEQwTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTI 97
Cdd:pfam01053 1 DTLAVHAGQRPDP-QTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAiTAAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 98 THLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK------------------------- 152
Cdd:pfam01053 80 LALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKavyletptnpllkvvdieaiaklak 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG 214
Cdd:pfam01053 160 khgilvvvdntfaspylqRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 215 LKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLA 294
Cdd:pfam01053 240 LKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDNLKLFSLA 319
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 25453487 295 ESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:pfam01053 320 VSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVG 360
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
16-335 |
2.14e-161 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 457.20 E-value: 2.14e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 16 QHFATQAIHVGQDPEQWTsRAVVPPISLSTTFKQGAPGQ--------HSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAF 87
Cdd:COG0626 1 MGPATRAVHAGRDPDPQT-GAVSPPIYLTSTFVFPSAEAlaarfageEGGYIYSRYGNPTRRALEEALAALEGGEAALAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 88 ASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK-------------- 152
Cdd:COG0626 80 ASGMAAiSAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKlvfletpsnptlev 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -----------------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVP 203
Cdd:COG0626 160 vdiaaiaaiahaagallvvdntfatpllqRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 204 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI 283
Cdd:COG0626 240 SPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAARR 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 25453487 284 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:COG0626 320 FLDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVG 371
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
36-335 |
5.58e-157 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 445.11 E-value: 5.58e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 36 AVVPPISLSTTFKQGAP--------GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQ 106
Cdd:cd00614 2 AVAPPIYQTSTFVFPSPaeaadlfaLREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAiSTVLLALLKAGDH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 107 IICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------------------------- 152
Cdd:cd00614 82 VVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKlvyvesptnptlkvvdieaiaelahehgallvvd 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ---------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRME 223
Cdd:cd00614 162 ntfatpylqRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRME 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 224 KHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESL 303
Cdd:cd00614 242 RHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVESL 321
|
330 340 350
....*....|....*....|....*....|..
gi 25453487 304 AELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:cd00614 322 VEHPASMTHSQLPPEERAAAGITPGLVRLSVG 353
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
13-335 |
5.87e-131 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 379.76 E-value: 5.87e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 13 PHFQHFATQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQ-HSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGL 91
Cdd:PRK07811 8 HANQGFATRAIHAGYEPDPATG-AVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 92 AAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK------------------ 152
Cdd:PRK07811 87 AATdCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKliwvetptnpllsitdia 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -------------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPID 207
Cdd:PRK07811 167 alaelahdagakvvvdntfaspylqQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPFD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 208 CYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKN 287
Cdd:PRK07811 247 AYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGEEAARDFCAR 326
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 25453487 288 LKLFTLAESLGGFESLAELPAIMTHASVLKNDrdvLGISDTLIRLSVG 335
Cdd:PRK07811 327 TKVFTLAESLGGVESLIEHPSAMTHASTAGSQ---LEVPDDLVRLSVG 371
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
20-335 |
1.06e-117 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 345.56 E-value: 1.06e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 20 TQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITH 99
Cdd:PRK07671 5 TKLIHGGIIGDPSTG-AVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 100 LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK--------------------------- 152
Cdd:PRK07671 84 LFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKaiyvetptnpllkitdikkistiakek 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ----------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLK 216
Cdd:PRK07671 164 glltivdntfmtpywqSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 217 TLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIkGTLQHAEIFLKNLKLFTLAES 296
Cdd:PRK07671 244 TLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLAES 322
|
330 340 350
....*....|....*....|....*....|....*....
gi 25453487 297 LGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK07671 323 LGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVG 361
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
17-335 |
1.08e-111 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 330.71 E-value: 1.08e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHvGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT 96
Cdd:PRK06176 2 RMQTKLIH-GGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 97 ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK------------------------ 152
Cdd:PRK06176 81 VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKalyletpsnpllkitdlaqcasva 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 213
Cdd:PRK06176 161 kdhglltivdntfatpyyqNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 214 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQhAEIFLKNLKLFTL 293
Cdd:PRK06176 241 GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSE-AVAFVESLKLFIL 319
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 25453487 294 AESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK06176 320 GESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVG 361
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
19-353 |
5.73e-97 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 292.89 E-value: 5.73e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVGQDPEQWTsrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTIT 98
Cdd:TIGR01329 2 STLLVNTDNKNDPYD--ASSMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVIT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 99 HLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK-------------------------- 152
Cdd:TIGR01329 80 RLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKlvllesptnplqkivdirkisemaha 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -----------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGL 215
Cdd:TIGR01329 160 qnalvvvdntmmspllcNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 216 KTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGcTGMVTFYIKGTLQHAEIFLKNLKLFTLAE 295
Cdd:TIGR01329 240 KTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKG-AGSVLSFETGSVALSKRLVEATKLFSITV 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 25453487 296 SLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 353
Cdd:TIGR01329 319 SFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFVTA 376
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
18-357 |
7.37e-92 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 280.12 E-value: 7.37e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 18 FATQAIH--VGQDPEqwtSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATV 95
Cdd:PRK08064 7 IDTLLLHnqYKHDKQ---TGAVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAIS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 96 TITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK----------------------- 152
Cdd:PRK08064 84 TAFLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKlfyvetpsnpllkvtdirgvvkl 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 --------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 212
Cdd:PRK08064 164 akaigcltfvdntfltpllqKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 213 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFyikgTLQHAEI---FLKNLK 289
Cdd:PRK08064 244 RGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSF----TLQSEEAvrqFVSHVK 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25453487 290 LFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPS 357
Cdd:PRK08064 320 LPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEEPV 387
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
36-335 |
2.70e-90 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 275.91 E-value: 2.70e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 36 AVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVY 114
Cdd:TIGR02080 21 CVVPPIYLSTTYNFTGFNEPRAYDYSRSGNPTRDLLQQALAELEGGAGAVVTNTGMSAiHLVTTALLGPDDLLVAPHDCY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 115 GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI-------------------------------------------TPET 151
Cdd:TIGR02080 101 GGTYRLLNALAKKGCFRVLFVDQGDEQALRAALaqkpklvlietpsnpllrvvdiakichlakavgavvvvdntflSPAL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 152 KRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMA 231
Cdd:TIGR02080 181 QNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTLRGLRTLVARMRLQQRNAQA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 232 VAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMT 311
Cdd:TIGR02080 261 IVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGEQTVRRFLGGLSLFTLAESLGGVESLIAHPATMT 340
|
330 340
....*....|....*....|....
gi 25453487 312 HASVLKNDRDVLGISDTLIRLSVG 335
Cdd:TIGR02080 341 HAAMGPEARAEAGISDTLLRLSVG 364
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
16-335 |
2.55e-88 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 270.42 E-value: 2.55e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 16 QHFATQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATV 95
Cdd:PRK08247 3 STIETKLAQIGNRSDERTG-TVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 96 TITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK----------------------- 152
Cdd:PRK08247 82 LVMSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKaifietptnplmqetdiaaiaki 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 --------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 212
Cdd:PRK08247 162 akkhglllivdntfytpvlqRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLLI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 213 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLpshpqhelvkrqctgcTGMVTFyikgTLQHAE---IFLKNLK 289
Cdd:PRK08247 242 RGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYPGR----------------GGMLSF----RLQDEEwvnPFLKSLK 301
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 25453487 290 LFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08247 302 LITFAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVG 347
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
18-335 |
4.56e-88 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 270.93 E-value: 4.56e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 18 FATQAIHVGQDPE-QWTSRAVvpPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFA 88
Cdd:PRK06234 9 FATKAIHGGHIGDkQFGSLAT--PIYQTSTFifdsaEQGGrrfAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 89 SGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK--------------- 152
Cdd:PRK06234 87 SGMGAiSSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKvvyletpanptlkvt 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ------------------------------RPLALGADISMYSATKYMNGHSDVVMGLVsVNCESLHNRLRF--LQNSLG 200
Cdd:PRK06234 167 dikaisniahennkeclvfvdntfctpyiqRPLQLGADVVVHSATKYLNGHGDVIAGFV-VGKEEFINQVKLfgIKDMTG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 201 AVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQH 280
Cdd:PRK06234 246 SVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEE 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 25453487 281 AEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK06234 326 GKVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVG 380
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
13-335 |
1.05e-87 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 270.75 E-value: 1.05e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 13 PHFQHFATQAIHVGQDPEQwTSRAVVPPISLSTTFK-----QGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC 84
Cdd:COG2873 3 EKKYGFETLALHAGQEPDP-TTGARAVPIYQTTSYVfddaeHAAdlfALKEPGNIYTRIMNPTTDVLEKRIAALEGGVAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 85 LAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK----------- 152
Cdd:COG2873 82 LATASGQAAiTLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKaifgetignpa 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 --------------------------------RPLALGADISMYSATKYMNGHSDVVMGLVsVNC--------------- 185
Cdd:COG2873 162 ldvldieaiaeiahehgvplivdntfatpylcRPIEHGADIVVHSATKYIGGHGTSIGGVI-VDGgnfdwaangkfpelt 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 186 ---ESLHN----------------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVI 246
Cdd:COG2873 241 epdPSYHGlvyteafgnaafitkaRVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 247 YPGLPSHPQHELVKRQCT-GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGI 325
Cdd:COG2873 320 YPGLPSHPYHELAQKYLPkGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGV 399
|
410
....*....|
gi 25453487 326 SDTLIRLSVG 335
Cdd:COG2873 400 TPDLIRLSVG 409
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
36-335 |
4.29e-86 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 268.05 E-value: 4.29e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 36 AVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYG 115
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYG 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 116 GTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK------------------------------------------- 152
Cdd:PLN02509 183 GSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKlvwlesptnprqqisdirkiaemahaqgalvlvdnsimspvls 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAV 232
Cdd:PLN02509 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKI 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 233 AQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGcTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTH 312
Cdd:PLN02509 343 AMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKG-AGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSH 421
|
330 340
....*....|....*....|...
gi 25453487 313 ASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PLN02509 422 ASIPAEVREARGLTEDLVRISAG 444
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
18-356 |
6.01e-86 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 265.51 E-value: 6.01e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 18 FATQAIHVGQDPEQwTSRAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFAS 89
Cdd:PRK07503 10 FSTRAIHHGYDPLD-HGGALVPPVYLTATFafptaEYGAecfAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALAS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 90 GLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------- 152
Cdd:PRK07503 89 GMGAiTATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRmvyfetpanpnmrlvd 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ---------------------------RPLALGADISMYSATKYMNGHSDVVMGLVsVNCESLHNRLRF--LQNSLGAVP 203
Cdd:PRK07503 169 iaavaeiahgagakvvvdntyctpylqRPLELGADLVVHSATKYLGGHGDITAGLV-VGGKALADRIRLegLKDMTGAVM 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 204 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI 283
Cdd:PRK07503 248 SPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAAGRR 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25453487 284 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPP 356
Cdd:PRK07503 328 FMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALDACAVA 400
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
16-351 |
3.71e-80 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 250.14 E-value: 3.71e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 16 QHFATQAIHVGQDPEQWTSrAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAF 87
Cdd:PRK06767 4 KHMETALIHHGYTSEEHKG-SLTPPLFQTSTFtfetaQQGEasfAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 88 ASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK-------------- 152
Cdd:PRK06767 83 GSGMAAiSATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKlifvetpinptmkl 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -----------------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVP 203
Cdd:PRK06767 163 idlkqvirvakrngllvivdntfcspylqRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 204 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYpglpshPQHELVKRQCTGCTGMVTFYIKGTLQHAEI 283
Cdd:PRK06767 243 APFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEETQA 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25453487 284 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 351
Cdd:PRK06767 317 FINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALK 384
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
15-335 |
2.13e-77 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 242.89 E-value: 2.13e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 15 FQHFATQAIHVGQ--DPEQWTsraVVPPISLSTTF------KQGAPGQHSG--FEYSRSGNPTRNCLEKAVAALDGAKYC 84
Cdd:PRK06434 6 LNGFNTRAVQSGElrDPRFGN---VTTPIFETSTFvypnseKEAYMDSTRGmpYIYTRWGNPTVQAFEEKYAVLENAEHA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 85 LAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLE-----------AAIT---- 148
Cdd:PRK06434 83 LSFSSGMGAiTSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLDfdpsnydliyaESITnptl 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 149 -------------------------PETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVP 203
Cdd:PRK06434 163 kvpdiknvssfchendvivdatfasPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 204 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLpshpqhELVKRQCTGCTGMVTFYIKgTLQHAEI 283
Cdd:PRK06434 243 DPIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELR-SMEDVHK 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 25453487 284 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK06434 316 FIRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIG 367
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
17-335 |
2.73e-77 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 243.36 E-value: 2.73e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQDPEQwTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT 96
Cdd:PRK08776 12 SAATAAVRAGIDRDT-AYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 97 ITH-LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIK------------------------------LLEA 145
Cdd:PRK08776 91 VLNaLLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRsladalaqspklvlietpsnpllritdlrfVIEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 146 A-------------ITPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 212
Cdd:PRK08776 171 AhkvgaltvvdntfLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLTL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 213 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFT 292
Cdd:PRK08776 251 RGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVDGLRYFT 330
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 25453487 293 LAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08776 331 LAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVG 373
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
17-335 |
9.78e-75 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 236.05 E-value: 9.78e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQD--PEQWTSRAVVPpiSLSTTFKQGA------PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFA 88
Cdd:PRK08133 6 GFDTLAVRAGQLrsPFGEHSEALFL--TSSFVFESAAeaaarfAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 89 SGLAATVTIT-HLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK--------------- 152
Cdd:PRK08133 84 SGMAAILAVVmALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKlffletpsnpltela 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ----------------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQnSLGAVPS 204
Cdd:PRK08133 164 diaalaeiahaagallvvdncfctpalqQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFLR-TAGPTLS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 205 PIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIF 284
Cdd:PRK08133 243 PFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAWRV 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 25453487 285 LKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08133 323 IDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVG 373
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
19-335 |
5.34e-74 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 234.40 E-value: 5.34e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVGQDPEQwTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTI 97
Cdd:PRK08861 7 ATIAVRTGIESDS-QYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSAlNLWV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 98 THLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI------------------------------ 147
Cdd:PRK08861 86 SALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALakkpklilletpsnplvrvvdiaelcqkak 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 -------------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG 214
Cdd:PRK08861 166 avgalvavdntflTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTLRG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 215 LKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLA 294
Cdd:PRK08861 246 IRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKVFVKALALFSLA 325
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 25453487 295 ESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08861 326 ESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVG 366
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
19-335 |
1.18e-72 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 230.72 E-value: 1.18e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAI--HVGQDPeqwtSRAVVPPISLSTTFKQGAPGQHS--GFE--YSRSGNPTRNCLEKAVAALDGAKYCLAFASGLA 92
Cdd:PRK08574 4 GTDAVrgYRGSDP----YGSLQPPIYLTALFRQEGEAYPSdrGFDlkYSREENPTLRPLEEALAKLEGGVDALAFNSGMA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 93 ATVTI-THLLKAGDQIICMDDVYGGTNRYFRQVaSEFGLK-----------ISFVDCSK--------------------- 139
Cdd:PRK08574 80 AISTLfFSLLKAGDRVVLPMEAYGTTLRLLKSL-EKFGVKvvlaypstediIEAIKEGRtklvfietmtnptlkvidvpe 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 140 ----IKLLEAAI-------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDC 208
Cdd:PRK08574 159 vakaAKELGAILvvdntfaTPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 209 YLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKR--QCTGCTGMVTFYIKGTLQHAEIFLK 286
Cdd:PRK08574 239 YLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRlfGKDLYGGVVSFRVKGGRDAVLKFLR 318
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 25453487 287 NLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08574 319 SLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVG 367
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
17-335 |
1.25e-71 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 227.40 E-value: 1.25e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT 96
Cdd:PRK07269 6 HINTILAQAGIKSDEATG-ALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAIVL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 97 ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFglKISFVDCSKIKLLEAAITPET------------------------- 151
Cdd:PRK07269 85 AFSVFPVGSKVVAVRDLYGGSFRWFNQQEKEG--RFHFTYANTEEELIAAIEEDTdivyietptnplmvefdiekvakla 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 152 ------------------KRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 213
Cdd:PRK07269 163 hakgakvivdntfyspiyQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLMR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 214 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLpshpqhelvkrqctgcTGMVTFYI--KGTLQHaeiFLKNLKLF 291
Cdd:PRK07269 243 GLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGK----------------GGMISFKVadETRIPH---ILNSLKVF 303
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 25453487 292 TLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK07269 304 TFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIG 347
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
19-335 |
4.30e-71 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 226.70 E-value: 4.30e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVG-QDPEQWTsrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAAT-VT 96
Cdd:PRK08045 6 ATIAVRSGlNDDEQYG--CVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIhLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 97 ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS-------------KIKLLE------------AAI---- 147
Cdd:PRK08045 84 TTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGdeqalraalaekpKLVLVEspsnpllrvvdiAKIchla 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 --------------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 213
Cdd:PRK08045 164 reagavsvvdntflSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 214 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTL 293
Cdd:PRK08045 244 GLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTL 323
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 25453487 294 AESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08045 324 AESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTG 365
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
17-335 |
4.93e-71 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 226.93 E-value: 4.93e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQDpEQWTSRAVVPPISLSTTFK--------QGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFA 88
Cdd:PRK08249 8 GVGTKAVWAGEK-EYLPYGATQVPVVLSVAYGyddidewyDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 89 SGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI-------------------- 147
Cdd:PRK08249 87 TGMAAiSNTLYTFLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIakgcdllyletptnptlkiv 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 -----------------------TPETKRPLALGADISMYSATKYMNGHSDVvMGLVSVNCESLHNRLRFLQNSLGAVPS 204
Cdd:PRK08249 167 dierlaaaakkvgalvvvdntfaTPINQNPLALGADLVIHSATKFLSGHADA-LGGVVCGSKELMEQVYHYREINGATMD 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 205 PIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIF 284
Cdd:PRK08249 246 PMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKRL 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 25453487 285 LKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK08249 326 LPKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVG 376
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
17-335 |
2.41e-70 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 225.70 E-value: 2.41e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQDPEQWT-SRAVvpPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAF 87
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTgSRAV--PIYQTTSYvfdstEHAAALfglQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 88 ASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK-------------- 152
Cdd:TIGR01326 79 ASGQAAiTYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKavfaetignpqinv 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -----------------------------RPLALGADISMYSATKYMNGHSDVVMGLV----------------SVNCES 187
Cdd:TIGR01326 159 ldieaiaevahrhgiplivdntfatpylcRPIKHGADIVVHSATKYIGGHGTAIGGVIvdggkfdwnngrfplfTTPDPS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 188 LHN----------------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLP 251
Cdd:TIGR01326 239 YHGlvftetlgnpafilkaRVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 252 SHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 330
Cdd:TIGR01326 318 SHPHHALAKKYLPKGFGAVlSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLI 397
|
....*
gi 25453487 331 RLSVG 335
Cdd:TIGR01326 398 RLSVG 402
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
53-335 |
3.94e-66 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 213.94 E-value: 3.94e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 53 GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLK 131
Cdd:TIGR01325 41 GELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMAAIFAaLMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 132 ISFVDCSKIKLLEAAITPETK-------------------------------------------RPLALGADISMYSATK 168
Cdd:TIGR01325 121 TVFVDGTDLSAWEAALKPNTKavfvetpsnplqelvdiaavaelahaagakvvvdnvfatpllqQPLKLGADVVVYSATK 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 169 YMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYP 248
Cdd:TIGR01325 201 HIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPFNAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYP 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 249 GLPSHPQHELVKRQCTGCTGMVTFYIKGTlQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDT 328
Cdd:TIGR01325 281 GLPSHPQHELAKRQMSGGGTVVTFDLDCR-QAAFKVLDAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDG 359
|
....*..
gi 25453487 329 LIRLSVG 335
Cdd:TIGR01325 360 LVRLSVG 366
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
14-335 |
3.59e-63 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 207.22 E-value: 3.59e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 14 HFQHFATQAIHVGQDPEqWTSRAVVPPISLSTTF------------------KQGAPGQHSGFEYSRSGNPTRNCLEKAV 75
Cdd:PRK07049 14 RELHPETQMLNYGYDPE-LSEGAVKPPVFLTSTFvfrsaedgrdffdyvsgrKEPPAGEGAGLVYSRFNHPNSEIVEDRL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 76 AALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLK-ISFVDCSKIKLLEAAI------ 147
Cdd:PRK07049 93 AVYEGAESAALFSSGMSAiATTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaak 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 ---------TPET---------------------------------------KRPLALGADISMYSATKYMNGHSDVVMG 179
Cdd:PRK07049 173 grvslilieTPANptnslvdvaavrrvadaiearqghrpiiacdntllgpvfQKPLEHGADLSVYSLTKYVGGHSDLVAG 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 180 LVSVNcESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGL--PSHPQHE 257
Cdd:PRK07049 253 AVLGR-KALIRQVRALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGA 331
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25453487 258 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK07049 332 VYKRQCTGAGSTFSFDIKGGQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIG 409
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
19-335 |
4.43e-63 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 205.84 E-value: 4.43e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVGQDPEqwtSRAVVPPISLSTTFKqgAPGQHSgFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTI 97
Cdd:PRK06460 4 ATRTVREDIDEA---TGAITTPIYQTTAYH--YPEGEK-YRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAiSTTA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 98 THLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI------------------------------ 147
Cdd:PRK06460 78 LALLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKskrydvvfvenitnpllrvvditelskvck 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 -------------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCEsLHNRLRFLQNSLGAVPSPIDCYLCNRG 214
Cdd:PRK06460 158 engsilivdatfsTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGK-LLNVIDQMRRTLGTSLDPHAAYLTLRG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 215 LKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLA 294
Cdd:PRK06460 237 IKTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIPA 316
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 25453487 295 ESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK06460 317 QTLGGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVG 357
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
20-353 |
1.88e-58 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 195.06 E-value: 1.88e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 20 TQAIHVGQDPEQWT-SRAVvpPISLSTT--FKQGAPG------QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASG 90
Cdd:PRK08248 11 TLAIHAGQEIDPTTgSRAV--PIYQTTSygFRDSEHAanlfslKEFGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 91 LAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK----------------- 152
Cdd:PRK08248 89 QAAiTYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKalfaetignpkgdvldi 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 --------------------------RPLALGADISMYSATKYMNGHSDVVMGLVS------------------------ 182
Cdd:PRK08248 169 eavaaiahehgiplivdntfaspyllRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsgkfpgltepdpsyh 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 183 --VNCESL-------HNRLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSH 253
Cdd:PRK08248 249 glVYTDAVgeaayitKARVQLLRD-LGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPSH 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 254 PQHELVKRQC-TGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRL 332
Cdd:PRK08248 328 PSYELAKKYLpKGQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVRL 407
|
410 420
....*....|....*....|.
gi 25453487 333 SVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK08248 408 SVGTEAIDDILDDLRQAIRQS 428
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
18-353 |
1.09e-55 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 188.02 E-value: 1.09e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 18 FATQAIHVGQDPEQWT-SRAVvpPISLSTTF-----KQGAP---GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFA 88
Cdd:PRK08134 9 FDTLALHAGAAPDPATgARAV--PIHLTTSFvfrdsDHAAAlfnLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 89 SGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK--------------- 152
Cdd:PRK08134 87 SGQAAlHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRllfgetlgnpglevl 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ----------------------------RPLALGADISMYSATKYMNGHSDVVMGLV----------SVNCESL------ 188
Cdd:PRK08134 167 diptvaaiaheagvpllvdstfttpyllRPFEHGADLVYHSATKFLGGHGTAIGGVLvdggrfdweaSGKFPELtepyag 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 189 -HNR------------LRFLQNSL---GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPS 252
Cdd:PRK08134 247 fHGMvfaeestvaaflLRARREGLrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELES 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 253 HPQHELVKRQC-TGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIR 331
Cdd:PRK08134 327 HPDHALAKRLLpRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIR 406
|
410 420
....*....|....*....|..
gi 25453487 332 LSVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK08134 407 LSIGLEDADDLIDDLKRALKAA 428
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
19-335 |
8.88e-55 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 183.66 E-value: 8.88e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIH-VGQDPEQWTSraVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKyCLAFASGLAA-TVT 96
Cdd:PRK07582 5 GTRSVHaGGPEAVPGEP--VLPGPVFAAPYHLSPGEPTGPDTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAAiTAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 97 ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS----------KIKLLE------------AAI------- 147
Cdd:PRK07582 82 LRALLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREAPTAgmaeaalagaDLVLAEtpsnpgldvcdlAALaaaahaa 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 -----------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLK 216
Cdd:PRK07582 162 gallvvdnttaTPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 217 TLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIkGTLQHAEIFLKNLKLFTLAES 296
Cdd:PRK07582 242 TLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASRLVVAATS 320
|
330 340 350
....*....|....*....|....*....|....*....
gi 25453487 297 LGGFESLAELPAIMTHAsvlkndrdvlgISDTLIRLSVG 335
Cdd:PRK07582 321 FGGVHTSADRRARWGDA-----------VPEGFVRLSCG 348
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
53-353 |
1.30e-54 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 184.19 E-value: 1.30e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 53 GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLK 131
Cdd:PRK07504 52 GEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAvTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 132 ISFVDCSKIKLLEAAITPETK-------------------------------------------RPLALGADISMYSATK 168
Cdd:PRK07504 132 STLVDGLDLDNWEKAVRPNTKvfflesptnptlevidiaavakianqagaklvvdnvfatplfqKPLELGAHIVVYSATK 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 169 YMNGHSDVVMGLV-SVNC---ESLHNRLRFLQNSLgavpSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEK 244
Cdd:PRK07504 212 HIDGQGRCLGGVVlSDKAwieEHLQDYFRHTGPSL----SPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVAR 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 245 VIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLG 324
Cdd:PRK07504 288 VIYPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELG 367
|
330 340
....*....|....*....|....*....
gi 25453487 325 ISDTLIRLSVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK07504 368 ISEGFLRLSAGLEDTDDLIEDLAAALKKV 396
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
20-335 |
3.21e-54 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 183.09 E-value: 3.21e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 20 TQAIHVGQDPEQWTSrAVVPPISLSTT--FKQGAP--GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-T 94
Cdd:PRK05967 15 TRLAHDGNDPGDYHG-FVNPPVVHASTvlFPDAETmaTRGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAvT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 95 VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------------- 152
Cdd:PRK05967 94 VPFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKvvhteapgsntfemqdipaiae 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ---------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNcESLHNRLRFLQNSLGAVPSPIDCYLC 211
Cdd:PRK05967 174 aahrhgaivmmdntwatplyfRPLDFGVDISIHAATKYPSGHSDILLGTVSAN-EKCWPQLLEAHGTLGLCAGPDDTYQI 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 212 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTL----QHAEIFLKN 287
Cdd:PRK05967 253 LRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPekgkAKAHAFLDA 332
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 25453487 288 LKLFTLAESLGGFESLAeLPAIMTHASVLKNDRDvlgisDTLIRLSVG 335
Cdd:PRK05967 333 LEIFGLGYSWGGYESLA-LHVKLGDRTVAKAPYA-----GPVIRLQIG 374
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
17-335 |
3.89e-54 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 184.18 E-value: 3.89e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQDPEQWT-SRAVvpPI--SLSTTFKQGAPGQ------HSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAF 87
Cdd:PRK07812 13 SFETKQIHAGQTPDPATnARAL--PIyqTTSYTFDDTDHAAalfglaEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 88 ASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV-DCSKIKLLEAAITPETK------------- 152
Cdd:PRK07812 91 ASGQAAeTFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKaffaetisnpqid 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ------------------------------RPLALGADISMYSATKYMNGHSDVVMGLV----------------SVNCE 186
Cdd:PRK07812 171 vldipgvaevaheagvplivdntiatpyliRPLEHGADIVVHSATKYLGGHGTAIAGVIvdggtfdwtqgrfpgfTTPDP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 187 SLHN---------------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLP 251
Cdd:PRK07812 251 SYHGvvfaelgppayalkaRVQLLRD-LGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLP 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 252 SHPQHELVKRQCTGCTG-MVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 330
Cdd:PRK07812 330 SSPWYERAKRLAPKGTGaVLSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLV 409
|
....*
gi 25453487 331 RLSVG 335
Cdd:PRK07812 410 RLAVG 414
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
20-335 |
2.47e-53 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 180.46 E-value: 2.47e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 20 TQAIHVGQDPEQWtSRAVVPPISLSTT--FKQGAP--GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-T 94
Cdd:TIGR01324 1 TRLIHSGRQPRFS-QGSVNPPLQRASTvlFDSHAAqrRAKGELTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAvT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 95 VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------------- 152
Cdd:TIGR01324 80 NSILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKvlfleapssitfeiqdipaiak 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ---------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVnCESLHNRLRFLQNSLGAVPSPIDCYLC 211
Cdd:TIGR01324 160 aarnpgivimidntwaagllfKPLEHGVDISIQAGTKYLVGHSDIMIGTVVA-NARTWDQLREHSYLMGQMVDADDAYTT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 212 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHA-EIFLKNLKL 290
Cdd:TIGR01324 239 LRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRLTQKQvHAFLDHLQL 318
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 25453487 291 FTLAESLGGFESLAeLP--AIMTHASVLKNDrdvlgISDTLIRLSVG 335
Cdd:TIGR01324 319 FGLGYSWGGYESLA-LCnqPELGHRPNIKRN-----LEGPLIRVHIG 359
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
20-353 |
3.01e-53 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 181.25 E-value: 3.01e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 20 TQAIHVGQDPEQwTSRAVVPPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGL 91
Cdd:PRK06084 5 TLAIHAGYSPDP-TTKAVAVPIYQTTSYafddtQHGADLfdlKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVASGM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 92 AA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK------------------ 152
Cdd:PRK06084 84 AAiTYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKavfcesignpagniidiq 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -------------------------RPLALGADISMYSATKYMNGHSDVVMGLV------------------SVNCESLH 189
Cdd:PRK06084 164 aladaahrhgvplivdntvatpvlcRPFEHGADIVVHSLTKYIGGHGTSIGGIVvdsgkfpwaehkerfallNTPDPSYH 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 190 N--------------RLRFLQ-NSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHP 254
Cdd:PRK06084 244 GvtyteafgpaafigRCRVVPlRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPDHP 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 255 QHELVKRQCTGC-TGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVlkNDRDVL--GISDTLIR 331
Cdd:PRK06084 324 EHELARRYMGGKpASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQL--NDEELEkaGVSRDMVR 401
|
410 420
....*....|....*....|..
gi 25453487 332 LSVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK06084 402 LSIGIEHIDDIIADLAQALDAS 423
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
8-353 |
4.20e-53 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 179.89 E-value: 4.20e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 8 SQGFLPHfqhfaTQAIHVGQDPEQWTSRAVVPPI---SLsTTFKQGAP------GQHSGFEYSRSGNPTRNCLEKAVAAL 78
Cdd:PRK05968 2 NDGLDPF-----DLAALITAHDEGNAFDAVVPPIfqtSL-FTFDSYDEmedvyaGEKVRPIYSRGDNPTVRAFEEMLAKL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 79 DGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS------------KIKLLE- 144
Cdd:PRK05968 76 EGAEDARGFASGMAAiSSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRdeeavakalpgaKLLYLEs 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 145 --------------AAI---------------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVsVNCESLHNRLRFL 195
Cdd:PRK05968 156 ptswvfelqdvaalAALakrhgvvtmidnswaSPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVV-AGSKEHIARINAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 196 QNS-LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELvkrqcTGCTGMVTFYI 274
Cdd:PRK05968 235 AYPyLGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSFIF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 275 KGTLQHAEiFLKNLKLFTLAESLGGFESLAeLPA-IMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK05968 310 REGIDVRA-FADALKLFRLGVSWGGHESLV-VPAeVVLQQKAQPNSAARFGVSPRSVRLHVGLEGTEALWADLEQALAAA 387
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
18-353 |
3.61e-51 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 176.06 E-value: 3.61e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 18 FATQAIHVGQDPEQwTSRAVVPPISLSTTF-----KQGAP--G-QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFAS 89
Cdd:PRK05994 8 FATLAVHAGAQPDP-TTGARATPIYQTTSFvfndaDHAASlfGlQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVAS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 90 GLAATVTITH-LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------- 152
Cdd:PRK05994 87 GHAAQFLVFHtLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKaifiesianpggtvtd 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ---------------------------RPLALGADISMYSATKYMNGHSDVVMGLVsVNC-------------------- 185
Cdd:PRK05994 167 iaaiaevahraglplivdntlaspyliRPIEHGADIVVHSLTKFLGGHGNSMGGII-VDGgtfdwsksgkypmlseprpe 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 186 -------ESLHN-------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLP 251
Cdd:PRK05994 246 yhglvlhETFGNfafaiaaRVLGLRD-LGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLP 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 252 SHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 330
Cdd:PRK05994 325 DDPYHALAQKYSPKGAGAVfTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVV 404
|
410 420
....*....|....*....|...
gi 25453487 331 RLSVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK05994 405 RLSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
19-335 |
5.03e-49 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 169.53 E-value: 5.03e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVGQDpEQWTSRAVVPPISLSTTF--------KQGAPGQHSG-FEYSRSGNPTRNCLEKAVAALDGAKYCLAFAS 89
Cdd:PRK09028 6 ATKIVSAGRD-KKWTKGVINPPVFRASTVvfdtvaemRHAAKNRANGeMFYGRRGTPTHFAFQAAIVELEGGAGTALYPS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 90 GLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------- 152
Cdd:PRK09028 85 GAAAiSNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKvlflespgsitmevqd 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ---------------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNcESLHNRLRFLQNSLGAVPSP 205
Cdd:PRK09028 165 vptlsriahehdivvmldntwaspinsRPFEMGVDISIQAATKYIVGHSDVMLGTATAN-EKHWDQLREHSYLMGQCTSP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 206 IDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIK-GTLQHAEIF 284
Cdd:PRK09028 244 DDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDPKAVTAL 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 25453487 285 LKNLKLFTLAESLGGFESLaelpaIMTHASVlKNDRDVL--GISDTLIRLSVG 335
Cdd:PRK09028 324 VEGMQHFKMGFSWGGFESL-----ILGVFGI-NKLRTATnwDFSKPLIRLHIG 370
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
12-335 |
3.26e-48 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 167.60 E-value: 3.26e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 12 LPHFQHFATQAIHVGQDPEQWTSRAvvPPISLSTTF--------KQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY 83
Cdd:PRK07810 10 LPDGVSQATIGVRGGLLRSGFEETA--EALYLTSGYvyesaaaaEAAFTGELDRFVYSRYGNPTVSMFEERLRLIEGAEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 84 CLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI--------------- 147
Cdd:PRK07810 88 CFATASGMSAVFTaLGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALsvptqavffetpsnp 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 148 ----------------------------TPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSL 199
Cdd:PRK07810 168 mqslvdiaavselahaagakvvldnvfaTPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRHT 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 200 GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTL- 278
Cdd:PRK07810 248 GPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPEd 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 279 ---QHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PRK07810 328 aakKRAFEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVG 387
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
36-353 |
1.31e-47 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 165.63 E-value: 1.31e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 36 AVVPPISLSTTFK-----------QGAPGqhsGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKA 103
Cdd:PRK05939 9 AVHKPIHTSVTYGyedardlidvfQGKKP---GFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAiAAVFLTLLRA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 104 GDQIICMDDVYGGTNRYFRQVAsEFGLKISFVDCSKIKLLEAAITPETK------------------------------- 152
Cdd:PRK05939 86 GDHLVSSQFLFGNTNSLFGTLR-GLGVEVTMVDATDVQNVAAAIRPNTRmvfvetianpgtqvadlagigalcrerglly 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ------------RPLALGADISMYSATKYMNGHSDVVMGLVS----------VNCESLHNR---------------LRfl 195
Cdd:PRK05939 165 vvdntmtspwlfRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwsayPNIFPAYRKgdpqqwgltqirkkgLR-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 196 qnSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIK 275
Cdd:PRK05939 243 --DMGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25453487 276 GTLQHAEiFLKNLKLFTLAESLGGFESLAeLPAIMT-HASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 353
Cdd:PRK05939 321 DGIDCFD-FLNRLKLVIKATHLGDTRTLV-IPVAPTiYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
17-335 |
6.06e-46 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 161.43 E-value: 6.06e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 17 HFATQAIHVGQD-PEQWTSraVVPPISLSTT--FKQGAP------GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAF 87
Cdd:PRK07050 9 ALQTRIVQPDDQiPPGFRS--FVTPVARASTvvFPDLATmraldwRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 88 ASGLAATVTITH-LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD-------------CSKIKLLEA-------- 145
Cdd:PRK07050 87 PSGLAAISLVYFgLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDpligagiadliqpNTRLIWLEApgsvtmev 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 146 ----AITPETK------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVP 203
Cdd:PRK07050 167 pdvpAITAAARargvvtaidntysaglafKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIGV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 204 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGM--VTFYIKGTLQHA 281
Cdd:PRK07050 247 SADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLfsVVFDERYSPAQV 326
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 25453487 282 EIFLKNLKLFTLAESLGGFESLAeLPAIMTHASVLKNDRDvlgisDTLIRLSVG 335
Cdd:PRK07050 327 DAFVEALELFAIGWSWGGACSLA-MPYDVASMRTAKWPHR-----GTLVRLYIG 374
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
18-335 |
4.61e-43 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 154.64 E-value: 4.61e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 18 FATQAIHVGQDPEQWTSRAVVPpISLSTTF--------KQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFAS 89
Cdd:PRK05613 14 FETRSIHAGQSVDSDTSARNLP-IYQTTSYvfdsaehaKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFAS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 90 GLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV-DCSKIKLLEAAITPETK--------------- 152
Cdd:PRK05613 93 GQAAeTAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKaffgetfanpqadvl 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 ----------------------------RPLALGADISMYSATKYMNGHSDVVMGLVS--------------------VN 184
Cdd:PRK05613 173 dipavaevahrnqvplivdntiataalvRPLELGADVVVASLTKFYTGNGSGLGGVLIdggkfdwtverdgkpvfpyfVT 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 185 CESLHNRLRF---------------LQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPG 249
Cdd:PRK05613 253 PDPAYHGLKYadlgapafglkaragLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAG 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 250 LPSHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDT 328
Cdd:PRK05613 333 LKDSPWYATKEKLGLKYTGSVlSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQA 412
|
....*..
gi 25453487 329 LIRLSVG 335
Cdd:PRK05613 413 TVRLSVG 419
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
16-335 |
3.91e-41 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 148.70 E-value: 3.91e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 16 QHFATQAIHVGQDPeQWTSRAVVPPI--SLSTTF------KQGAPGQHSG--FeYSRSGNPTRNCLEKAVAALDGAKYCL 85
Cdd:PRK08114 4 KKLDTQLVNAGRSK-KYTQGSVNSVIqrASSLVFdsveakKHATRNRANGelF-YGRRGTLTHFSLQEAMCELEGGAGCA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 86 AFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD-------------CSKIKLLEA--AITP 149
Cdd:PRK08114 82 LYPCGAAAvANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDpligadiakliqpNTKVVFLESpgSITM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 150 ETK------------------------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNcESLHNRLRflQNS- 198
Cdd:PRK08114 162 EVHdvpaivaavrsvnpdavimidntwaagvlfKALDFGIDISIQAGTKYLVGHSDAMIGTAVAN-ARCWEQLR--ENSy 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 199 -LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGT 277
Cdd:PRK08114 239 lMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKK 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25453487 278 LQHAEI--FLKNLKLFTLAESLGGFESL------AELPAIMTHASVlkndrdvlGISDTLIRLSVG 335
Cdd:PRK08114 319 LTDEQLanYLDNFSLFSMAYSWGGFESLilanqpEEIAAIRPAGEV--------DFTGTLIRLHIG 376
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
19-335 |
1.01e-36 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 137.49 E-value: 1.01e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 19 ATQAIHVGQDPEQWTSRavVPPISLSTTFKQGAPG--------QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASG 90
Cdd:PRK06702 8 GTICVQGGYTPKNGEPR--VLPLYQSTTYKYDTSDdlaalfnlEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 91 LAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS------------KIKLLEAA----------- 146
Cdd:PRK06702 86 QAAiMLAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNltadeivalandKTKLVYAEslgnpamnvln 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 147 ---------------------ITPETKRPLALGADISMYSATKYMNGHSDVVMGLVS---------------VNCESLHN 190
Cdd:PRK06702 166 fkefsdaakelevpfivdntlATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelVEPDPSYH 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 191 RLRFLQN----------------SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHP 254
Cdd:PRK06702 246 GVSYVQNfgaaayivkarvqllrDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 255 QHELVKRQCT-GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLS 333
Cdd:PRK06702 326 NYSLAQKYLKkGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLS 405
|
..
gi 25453487 334 VG 335
Cdd:PRK06702 406 VG 407
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
36-335 |
2.47e-32 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 125.26 E-value: 2.47e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 36 AVVPPISLSTTFKqGAPGQHSGFE-YSRSGNPTRNCLEKAVAALDG--AKYCLAfaSGLAA-TVTITHLLKAGDQIICMD 111
Cdd:PLN02242 46 TVMEPDTMRRMFS-GELGPDRDFYiYSRHFNPTVLNLGRQMAALEGteAAYCTA--SGMSAiSSVLLQLCSSGGHVVASN 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 112 DVYGGTNRYFRQ-VASEFGLKISFVDCSKIKLLEAAITP-ETK------------------------------------- 152
Cdd:PLN02242 123 TLYGGTHALLAHfLPRKCNITTTFVDITDLEAVKKAVVPgKTKvlyfesisnptltvadipelariahekgvtvvvdntf 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 153 -----RPLALGADISMYSATKYMNGHSDVVMGLVsvnC--ESLHNRLRFLQNS----LGAVPSPIDCYLCNRGLKTLHVR 221
Cdd:PLN02242 203 apmvlSPARLGADVVVHSISKFISGGADIIAGAV---CgpAELVNSMMDLHHGalmlLGPTMNPKVAFELSERLPHLSLR 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 222 MEKHFKNGMAVAQFLESNPWveKVIYPGLPSHPQHELVKRQ---CTGCTGMVTFYIkGTLQHAEIFLKNLKLFT----LA 294
Cdd:PLN02242 280 MKEHCRRAMEYAKRMKELGL--KVIYPGLEDHPQHALLKSMankGYGFGGLLCLDM-DTEERANRLMRYLQNSTqfgfMA 356
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 25453487 295 ESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 335
Cdd:PLN02242 357 VSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVG 397
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
71-152 |
1.60e-06 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 49.46 E-value: 1.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 71 LEKAVAALDGAKYCLAFASGLAATVTITHLL--KAGDQIICmddvyggTNRYFrqVAS-----EFGLKISFVDCSK---- 139
Cdd:cd00616 23 FEKAFAEYLGVKYAVAVSSGTAALHLALRALgiGPGDEVIV-------PSFTF--VATanailLLGATPVFVDIDPdtyn 93
|
90
....*....|....*
gi 25453487 140 --IKLLEAAITPETK 152
Cdd:cd00616 94 idPELIEAAITPRTK 108
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
71-152 |
1.14e-05 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 46.60 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 71 LEKAVAALDGAKYCLAFASGLAATVTITHLL--KAGDQIICmddvyggTNRYFrqVAS-----EFGLKISFVDCSK---- 139
Cdd:COG0399 35 FEEEFAAYLGVKHAVAVSSGTAALHLALRALgiGPGDEVIT-------PAFTF--VATanailYVGATPVFVDIDPdtyn 105
|
90
....*....|....*
gi 25453487 140 --IKLLEAAITPETK 152
Cdd:COG0399 106 idPEALEAAITPRTK 120
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
71-152 |
1.48e-04 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 43.43 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25453487 71 LEKAVAALDGAKYCLAFASGLAATVTITHLLKA--GDQIICMDDVYGGTNryfrQVASEFGLKISFVD------CSKIKL 142
Cdd:pfam01041 29 FERAFAAYLGVKHAIAVSSGTAALHLALRALGVgpGDEVITPSFTFVATA----NAALRLGAKPVFVDidpdtyNIDPEA 104
|
90
....*....|
gi 25453487 143 LEAAITPETK 152
Cdd:pfam01041 105 IEAAITPRTK 114
|
|
| |
