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Conserved domains on  [gi|119120877|ref|NP_597731|]
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zinc finger protein 721 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 12142358)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
218-608 5.89e-12

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.95  E-value: 5.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 218 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKC--KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKH 295
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 296 RRIHT----GEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYV-HRRIHTGEKPYKCEDCGKAF 370
Cdd:COG5048  111 SSSSSnsndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLISS 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 371 GRYTALNQHKKIHTGEKPYK----CEECGKaFNSSTNLTAHKRIHTREKPYTCEdRGRAFGLSTNLNEYKKIHTGDKPYk 446
Cdd:COG5048  191 NVSTSIPSSSENSPLSSSYSipssSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSSSDSSSSASESPRSSLPT- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 447 ckecgKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR--IHTGE--KPFECLE--CGKAFTSSTTLTKH 519
Cdd:COG5048  268 -----ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 520 RRIHTGEKPYTC--EVCGKAFRQSAILY-----VHRRIHTGEKPYTCE--ECGKTFRQSANLYVHRRIHTGEKP--YKCE 588
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNP 422

                        410       420
                 ....*....|....*....|
gi 119120877 589 ECGKAFGRYTDLNQHKKIHT 608
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
442-885 5.60e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.87  E-value: 5.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 442 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKC--KQCGKVITSSSSFAKHKRIHTGEKPFECLECG------KAFTSS 513
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsnskASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 514 TTLTKHRRIHTGEKPYTCevCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYV-HRRIHTGEKPYKCEECGK 592
Cdd:COG5048  111 SSSSSNSNDNNLLSSHSL--PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 593 AFGRYTDLNQHKKIHTGEKLYKceecgkdfvwYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 672
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYS----------IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 673 ECGKAFGWSIALNQHKKIHTGE-------KPYKCEECGKAFSRSRNLTTHRRvhtrekpykcedrgrsfgwstnlneyKK 745
Cdd:COG5048  259 ESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLR--------------------------SV 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 746 IHTGDKL--YKCKE--CGKVFKQSSHLNRHEKIHTGKKPYKCK--ECGKVITSSS------SFAKHKRIHTgEKPFKCL- 812
Cdd:COG5048  313 NHSGESLkpFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLs 391

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119120877 813 -ECGKAFTSSTTLTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKPYTCgECGKTFRQSANLYAHKK 885
Cdd:COG5048  392 nSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
151-176 3.23e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.23e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  151 DLNQHKKIHTGEKPYKCEECGKAFNR 176
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 161-241 1.46e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 161 GEKPYKCE--ECGKAFNRSTNLTAHKRI-HNREKAYTGEDRDRAFGWSTNlneykkihtgDKPYKCKECGKAFMHSSHLN 237
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPSPEKMNIFSAK----------DKPYRCEVCDKRYKNLNGLK 415


                 ....
gi 119120877 238 KHEK 241
Cdd:COG5189  416 YHRK 419
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
218-608 5.89e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.95  E-value: 5.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 218 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKC--KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKH 295
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 296 RRIHT----GEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYV-HRRIHTGEKPYKCEDCGKAF 370
Cdd:COG5048  111 SSSSSnsndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLISS 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 371 GRYTALNQHKKIHTGEKPYK----CEECGKaFNSSTNLTAHKRIHTREKPYTCEdRGRAFGLSTNLNEYKKIHTGDKPYk 446
Cdd:COG5048  191 NVSTSIPSSSENSPLSSSYSipssSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSSSDSSSSASESPRSSLPT- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 447 ckecgKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR--IHTGE--KPFECLE--CGKAFTSSTTLTKH 519
Cdd:COG5048  268 -----ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 520 RRIHTGEKPYTC--EVCGKAFRQSAILY-----VHRRIHTGEKPYTCE--ECGKTFRQSANLYVHRRIHTGEKP--YKCE 588
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNP 422

                        410       420
                 ....*....|....*....|
gi 119120877 589 ECGKAFGRYTDLNQHKKIHT 608
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
442-885 5.60e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.87  E-value: 5.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 442 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKC--KQCGKVITSSSSFAKHKRIHTGEKPFECLECG------KAFTSS 513
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsnskASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 514 TTLTKHRRIHTGEKPYTCevCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYV-HRRIHTGEKPYKCEECGK 592
Cdd:COG5048  111 SSSSSNSNDNNLLSSHSL--PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 593 AFGRYTDLNQHKKIHTGEKLYKceecgkdfvwYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 672
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYS----------IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 673 ECGKAFGWSIALNQHKKIHTGE-------KPYKCEECGKAFSRSRNLTTHRRvhtrekpykcedrgrsfgwstnlneyKK 745
Cdd:COG5048  259 ESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLR--------------------------SV 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 746 IHTGDKL--YKCKE--CGKVFKQSSHLNRHEKIHTGKKPYKCK--ECGKVITSSS------SFAKHKRIHTgEKPFKCL- 812
Cdd:COG5048  313 NHSGESLkpFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLs 391

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119120877 813 -ECGKAFTSSTTLTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKPYTCgECGKTFRQSANLYAHKK 885
Cdd:COG5048  392 nSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
683-708 3.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.17e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  683 ALNQHKKIHTGEKPYKCEECGKAFSR 708
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
375-400 3.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.17e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  375 ALNQHKKIHTGEKPYKCEECGKAFNS 400
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
151-176 3.23e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.23e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  151 DLNQHKKIHTGEKPYKCEECGKAFNR 176
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 161-241 1.46e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 161 GEKPYKCE--ECGKAFNRSTNLTAHKRI-HNREKAYTGEDRDRAFGWSTNlneykkihtgDKPYKCKECGKAFMHSSHLN 237
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPSPEKMNIFSAK----------DKPYRCEVCDKRYKNLNGLK 415


                 ....
gi 119120877 238 KHEK 241
Cdd:COG5189  416 YHRK 419
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
218-608 5.89e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.95  E-value: 5.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 218 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKC--KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKH 295
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 296 RRIHT----GEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYV-HRRIHTGEKPYKCEDCGKAF 370
Cdd:COG5048  111 SSSSSnsndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLISS 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 371 GRYTALNQHKKIHTGEKPYK----CEECGKaFNSSTNLTAHKRIHTREKPYTCEdRGRAFGLSTNLNEYKKIHTGDKPYk 446
Cdd:COG5048  191 NVSTSIPSSSENSPLSSSYSipssSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSSSDSSSSASESPRSSLPT- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 447 ckecgKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR--IHTGE--KPFECLE--CGKAFTSSTTLTKH 519
Cdd:COG5048  268 -----ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 520 RRIHTGEKPYTC--EVCGKAFRQSAILY-----VHRRIHTGEKPYTCE--ECGKTFRQSANLYVHRRIHTGEKP--YKCE 588
Cdd:COG5048  343 ILLHTSISPAKEklLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNP 422

                        410       420
                 ....*....|....*....|
gi 119120877 589 ECGKAFGRYTDLNQHKKIHT 608
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
442-885 5.60e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.87  E-value: 5.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 442 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKC--KQCGKVITSSSSFAKHKRIHTGEKPFECLECG------KAFTSS 513
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsnskASSSSL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 514 TTLTKHRRIHTGEKPYTCevCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYV-HRRIHTGEKPYKCEECGK 592
Cdd:COG5048  111 SSSSSNSNDNNLLSSHSL--PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPpLPANSLSKDPSSNLSLLI 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 593 AFGRYTDLNQHKKIHTGEKLYKceecgkdfvwYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 672
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYS----------IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSAS 258

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 673 ECGKAFGWSIALNQHKKIHTGE-------KPYKCEECGKAFSRSRNLTTHRRvhtrekpykcedrgrsfgwstnlneyKK 745
Cdd:COG5048  259 ESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLR--------------------------SV 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 746 IHTGDKL--YKCKE--CGKVFKQSSHLNRHEKIHTGKKPYKCK--ECGKVITSSS------SFAKHKRIHTgEKPFKCL- 812
Cdd:COG5048  313 NHSGESLkpFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLs 391

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119120877 813 -ECGKAFTSSTTLTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKPYTCgECGKTFRQSANLYAHKK 885
Cdd:COG5048  392 nSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
155-569 1.83e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.33  E-value: 1.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 155 HKKIHTGEKPYKC--EECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEY-KKIHTGDKPYKCKECGKAFM 231
Cdd:COG5048   52 HIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLsSSSSNSNDNNLLSSHSLPPS 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 232 HSSHLNKHEKIHTGEKPYKCKEC-GKVISSSSSFAKHKRIHTGEKPFKclecgkAFNISTTLTKHRRIHTGEKPYTCEVC 310
Cdd:COG5048  132 SRDPQLPDLLSISNLRNNPLPGNnSSSVNTPQSNSLHPPLPANSLSKD------PSSNLSLLISSNVSTSIPSSSENSPL 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 311 GKAFRQSANLYVHRRIHTgEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGE---- 386
Cdd:COG5048  206 SSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssek 284

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 387 ---KPYKCEECGKAFNSSTNLTAHKR--IHTREkpytcedrgrafglstnlneykkihtGDKPYKCKE--CGKAFIHSLH 459
Cdd:COG5048  285 gfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGE--------------------------SLKPFSCPYslCGKLFSRNDA 338

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 460 LNKHEKIHTGKKPYKCK--QCGKVITSSS------SFAKHKRIHTgEKPFECL--ECGKAFTSSTTLTKHRRIHTGEKPY 529
Cdd:COG5048  339 LKRHILLHTSISPAKEKllNSSSKFSPLLnneppqSLQQYKDLKN-DKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPY 417

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|..
gi 119120877 530 TCE--VCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQS 569
Cdd:COG5048  418 NCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
499-905 2.40e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 2.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 499 KPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQS--AILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHR 576
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 577 RIHTGE-KPYKCEECGKAFGRY---TDLNQHKKIHTGEKLYKCEECGKDFVWYTDLNQQKKIYtgekpykcEECGKAFAP 652
Cdd:COG5048  112 SSSSNSnDNNLLSSHSLPPSSRdpqLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN--------SLSKDPSSN 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 653 STDLNQHTKILTGEQSYKCEECGKAfgWSI-ALNQHKKIHTGEKPYKCEECGKAF-------SRSRNLTTHRRVHTREKP 724
Cdd:COG5048  184 LSLLISSNVSTSIPSSSENSPLSSS--YSIpSSSSDQNLENSSSSLPLTTNSQLSpksllsqSPSSLSSSDSSSSASESP 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 725 YKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRH--EKIHTGK--KPYKCKE--CGKVITSSSSFAK 798
Cdd:COG5048  262 RSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCPYslCGKLFSRNDALKR 341

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 799 HKRIHTGEKPFKC--LECGKAFTSSTT-----LTKHRRIHTGEKPYTCE--ECGKAFRQSAILYVHRRIHTGEKP--YTC 867
Cdd:COG5048  342 HILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKN 421

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 119120877 868 GECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQS 905
Cdd:COG5048  422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
303-735 7.44e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.78  E-value: 7.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 303 KPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCG--ECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAfgRYTALNQHK 380
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPL--SNSKASSSS 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 381 KIHTGEKPYKCE-ECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLH 459
Cdd:COG5048  110 LSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLIS 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 460 LNKhekIHTGKKPYKCKQCGKVI------------TSSSSFAKHKRIHTGEKPFECleCGKAFTSSTTLTKHRRIHtgek 527
Cdd:COG5048  190 SNV---STSIPSSSENSPLSSSYsipssssdqnleNSSSSLPLTTNSQLSPKSLLS--QSPSSLSSSDSSSSASES---- 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 528 pYTCEVCGKAFRQSAILYVHRRIHTG-EKPYTCEECGKTFRQSANLYVHRR--IHTGE--KPYKCEE--CGKAFGRYTDL 600
Cdd:COG5048  261 -PRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDAL 339

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 601 NQHKKIHTGEKLYKCeecgkdfvwytDLNQQKKIYTGEKPYKceecgkafaPSTDLNQHTKILTGEQSYKCEECGKAFGW 680
Cdd:COG5048  340 KRHILLHTSISPAKE-----------KLLNSSSKFSPLLNNE---------PPQSLQQYKDLKNDKKSETLSNSCIRNFK 399

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 119120877 681 S---IALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFG 735
Cdd:COG5048  400 RdsnLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRR 457
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
93-492 1.62e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.62  E-value: 1.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877  93 FANSNKDKTrhtgekhFKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYT----------------DLNQHK 156
Cdd:COG5048   25 KSLSNAPRP-------DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplelsrhlrthhnnpsDLNSKS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 157 KIHTGEKPYKCEECGKAFNRSTNL-----------------TAHKRIHNREKAYTGEdrdraFGWSTNLNEY-KKIHTGD 218
Cdd:COG5048   98 LPLSNSKASSSSLSSSSSNSNDNNllsshslppssrdpqlpDLLSISNLRNNPLPGN-----NSSSVNTPQSnSLHPPLP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 219 KPYKCKECGKAFMHSSHLNKhekIHTGEKPYKCKECGKVISSSSSFAKHKRIHTgEKPFKCLECGKAFNISTTLTKHRRI 298
Cdd:COG5048  173 ANSLSKDPSSNLSLLISSNV---STSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 299 HTGEKPYTCEVCGKAFRQSANLYVHRRIHTGE-------KPYTCGECGKTFRQSANLYVHRR--IHTGE--KPYKC--ED 365
Cdd:COG5048  249 SSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySL 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 366 CGKAFGRYTALNQHKKIHTGEKPYKC--EECGKAFNSSTN-----LTAHKRIHTREKPYTCEDRG--RAFGLSTNLNEYK 436
Cdd:COG5048  329 CGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLSNSciRNFKRDSNLSLHI 408

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 119120877 437 KIHTGDKP--YKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHK 492
Cdd:COG5048  409 ITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 164-324 2.44e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.71  E-value: 2.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 164 PYKCEECGKAFNRSTNL--TAHKRIHNREKAYTGEDRDRAfGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLN---- 237
Cdd:COG5189  260 PSNEEMLYKYISPSQGSaeLFEESSLGFDYEFIHKSVGNK-EIRGGISTGEMIDVRKLPCTNSSSNGKLAHGGERNidtp 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 238 KHEKIHTGEKPYKCK--ECGKVISSSSSFaKHKRIHTgekpfkclECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFR 315
Cdd:COG5189  339 SRMLKVKDGKPYKCPveGCNKKYKNQNGL-KYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYK 409


                 ....*....
gi 119120877 316 QSANLYVHR 324
Cdd:COG5189  410 NLNGLKYHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 637-716 2.98e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 2.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 637 GEKPYKCE--ECGKAFAPSTDLNQHtkILTGEQSYKCEEcgkafgwSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTT 714
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYH--MLHGHQNQKLHE-------NPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 119120877 715 HR 716
Cdd:COG5189  417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
683-708 3.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.17e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  683 ALNQHKKIHTGEKPYKCEECGKAFSR 708
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
375-400 3.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.17e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  375 ALNQHKKIHTGEKPYKCEECGKAFNS 400
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
151-176 3.23e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.23e-04
                          10        20
                  ....*....|....*....|....*.
gi 119120877  151 DLNQHKKIHTGEKPYKCEECGKAFNR 176
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 296-381 3.92e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 3.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 296 RRIHT-GEKPYTCEV--CGKAFRQSANLYVHRrIHtgekpytcGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGR 372
Cdd:COG5189  340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM-LH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKN 410


                 ....*....
gi 119120877 373 YTALNQHKK 381
Cdd:COG5189  411 LNGLKYHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
571-594 1.27e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.27e-03
                          10        20
                  ....*....|....*....|....
gi 119120877  571 NLYVHRRIHTGEKPYKCEECGKAF 594
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 367-465 1.32e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.40  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 367 GKAFGRYTALNQHKKihtGEKPYKCE--ECGKAFNSSTNLTAHkRIHTREKPYTCEDRGRafgLSTNLNEYKkihtgDKP 444
Cdd:COG5189  331 GERNIDTPSRMLKVK---DGKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQKLHENPSP---EKMNIFSAK-----DKP 398

                         90       100
                 ....*....|....*....|.
gi 119120877 445 YKCKECGKAFIHSLHLNKHEK 465
Cdd:COG5189  399 YRCEVCDKRYKNLNGLKYHRK 419
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 520-601 1.42e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 520 RRIHT-GEKPYTCEV--CGKAFRQSAILYVHRrIHTGEKPYTCEECGKtfrQSANLYVHRrihtgEKPYKCEECGKafgR 596
Cdd:COG5189  340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM-LHGHQNQKLHENPSP---EKMNIFSAK-----DKPYRCEVCDK---R 407


                 ....*
gi 119120877 597 YTDLN 601
Cdd:COG5189  408 YKNLN 412
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
668-922 1.43e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 668 SYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSR--NLTTHRRVHTREKPYKCEDRGR------------- 732
Cdd:COG5048   33 PDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRplELSRHLRTHHNNPSDLNSKSLPlsnskasssslss 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 733 -------------------SFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLN-RHEKIHTGKKPYKCKE---CGKV 789
Cdd:COG5048  113 sssnsndnnllsshslppsSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHpPLPANSLSKDPSSNLSlliSSNV 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 790 ITSSSSFAK-HKRIHTGEKPFKCLECGKaFTSSTTLTKHRRIHTGEKPYTCE---------------ECGKAFRQSAILY 853
Cdd:COG5048  193 STSIPSSSEnSPLSSSYSIPSSSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQspsslsssdssssasESPRSSLPTASSQ 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 854 VHRRIHTGE-------KPYTCGECGKTFRQSANLYAHK--KIHTGE--KPYTCG--DCGKTFRQSANLYAHKKIHTGDKT 920
Cdd:COG5048  272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISP 351


                 ..
gi 119120877 921 IQ 922
Cdd:COG5048  352 AK 353
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 161-241 1.46e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 161 GEKPYKCE--ECGKAFNRSTNLTAHKRI-HNREKAYTGEDRDRAFGWSTNlneykkihtgDKPYKCKECGKAFMHSSHLN 237
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGLKYHMLHgHQNQKLHENPSPEKMNIFSAK----------DKPYRCEVCDKRYKNLNGLK 415


                 ....
gi 119120877 238 KHEK 241
Cdd:COG5189  416 YHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
347-370 2.13e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.13e-03
                          10        20
                  ....*....|....*....|....
gi 119120877  347 NLYVHRRIHTGEKPYKCEDCGKAF 370
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 469-548 2.37e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119120877 469 GKKPYKCK--QCGKVITSSSSFaKHKRIHTgekpfeclECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYV 546
Cdd:COG5189  346 DGKPYKCPveGCNKKYKNQNGL-KYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ..
gi 119120877 547 HR 548
Cdd:COG5189  417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
795-820 3.59e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 3.59e-03
                          10        20
                  ....*....|....*....|....*.
gi 119120877  795 SFAKHKRIHTGEKPFKCLECGKAFTS 820
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
824-848 3.66e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 3.66e-03
                          10        20
                  ....*....|....*....|....*
gi 119120877  824 LTKHRRIHTGEKPYTCEECGKAFRQ 848
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
767-788 4.54e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.54e-03
                          10        20
                  ....*....|....*....|..
gi 119120877  767 HLNRHEKIHTGKKPYKCKECGK 788
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGK 22
zf-H2C2_2 pfam13465
Zinc-finger double domain;
292-316 4.63e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.63e-03
                          10        20
                  ....*....|....*....|....*
gi 119120877  292 LTKHRRIHTGEKPYTCEVCGKAFRQ 316
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
516-540 4.63e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.63e-03
                          10        20
                  ....*....|....*....|....*
gi 119120877  516 LTKHRRIHTGEKPYTCEVCGKAFRQ 540
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
487-512 5.42e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.42e-03
                          10        20
                  ....*....|....*....|....*.
gi 119120877  487 SFAKHKRIHTGEKPFECLECGKAFTS 512
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 753-775 5.66e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 5.66e-03
                          10        20
                  ....*....|....*....|...
gi 119120877  753 YKCKECGKVFKQSSHLNRHEKIH 775
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
319-344 5.86e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.86e-03
                          10        20
                  ....*....|....*....|....*.
gi 119120877  319 NLYVHRRIHTGEKPYTCGECGKTFRQ 344
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
263-287 5.98e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.98e-03
                          10        20
                  ....*....|....*....|....*
gi 119120877  263 SFAKHKRIHTGEKPFKCLECGKAFN 287
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
544-568 6.04e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.04e-03
                          10        20
                  ....*....|....*....|....*
gi 119120877  544 LYVHRRIHTGEKPYTCEECGKTFRQ 568
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
235-256 7.49e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.49e-03
                          10        20
                  ....*....|....*....|..
gi 119120877  235 HLNKHEKIHTGEKPYKCKECGK 256
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGK 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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