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Conserved domains on  [gi|225735591|ref|NP_078880|]
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RNA polymerase II-associated protein 3 isoform 1 [Homo sapiens]

Protein Classification

RPAP3_C domain-containing protein( domain architecture ID 13326683)

RPAP3_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPAP3_C pfam13877
Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of ...
 546-636 7.01e-35

Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.


:

Pssm-ID: 464012  Cd Length: 91  Bit Score: 127.01  E-value: 7.01e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  546 PANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFD 625
Cdd:pfam13877   1 PRNAYEFERDWRRLRKSSDRLYLYLKSIPPSNLPKIFKNSLDPDLLGEILKALAEHFIENEDPALVLEILQGLSKVPRFD 80

                          90
                  ....*....|.
gi 225735591  626 MAVMFMSETEK 636
Cdd:pfam13877  81 LAVMFLSKAEK 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
126-372 4.75e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 101.62  E-value: 4.75e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYS 205
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 206 RRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqieaqqnkqqaise 285
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNL-------------------------------------------- 116

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 286 kdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGK 365
Cdd:COG0457  117 ---GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193


                 ....*..
gi 225735591 366 LNEAKQD 372
Cdd:COG0457  194 EVLLALL 200
 
Name Accession Description Interval E-value
RPAP3_C pfam13877
Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of ...
 546-636 7.01e-35

Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.


Pssm-ID: 464012  Cd Length: 91  Bit Score: 127.01  E-value: 7.01e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  546 PANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFD 625
Cdd:pfam13877   1 PRNAYEFERDWRRLRKSSDRLYLYLKSIPPSNLPKIFKNSLDPDLLGEILKALAEHFIENEDPALVLEILQGLSKVPRFD 80

                          90
                  ....*....|.
gi 225735591  626 MAVMFMSETEK 636
Cdd:pfam13877  81 LAVMFLSKAEK 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
126-372 4.75e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 101.62  E-value: 4.75e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYS 205
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 206 RRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqieaqqnkqqaise 285
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNL-------------------------------------------- 116

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 286 kdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGK 365
Cdd:COG0457  117 ---GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193


                 ....*..
gi 225735591 366 LNEAKQD 372
Cdd:COG0457  194 EVLLALL 200
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 136-267 1.16e-14

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 75.98  E-value: 1.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 136 LKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
Cdd:PLN03088   5 LEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLE 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 225735591 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTE 267
Cdd:PLN03088  85 EYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSV 136
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 133-383 1.32e-13

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 73.86  E-value: 1.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPyNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAA-- 210
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAyd 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  211 -----------------------------------RFALQKLEEAKKDYERVL---------------ELEPNNFEATNE 240
Cdd:TIGR00990 206 glgkyadalldltasciidgfrneqsaqaverllkKFAESKAKEILETKPENLpsvtfvgnylqsfrpKPRPAGLEDSNE 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  241 LRK---ISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQ-QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANA 316
Cdd:TIGR00990 286 LDEetgNGQLQLGLKSPESKADESYEEAARAFEKALDLGKLGEkEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVT 365

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 225735591  317 LLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
Cdd:TIGR00990 366 QSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDF 432
TPR_1 pfam00515
Tetratricopeptide repeat;
202-234 2.05e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 44.72  E-value: 2.05e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 225735591  202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNN 234
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 133-166 9.02e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.82  E-value: 9.02e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 225735591   133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN 166
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
RPAP3_C pfam13877
Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of ...
 546-636 7.01e-35

Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.


Pssm-ID: 464012  Cd Length: 91  Bit Score: 127.01  E-value: 7.01e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  546 PANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFD 625
Cdd:pfam13877   1 PRNAYEFERDWRRLRKSSDRLYLYLKSIPPSNLPKIFKNSLDPDLLGEILKALAEHFIENEDPALVLEILQGLSKVPRFD 80

                          90
                  ....*....|.
gi 225735591  626 MAVMFMSETEK 636
Cdd:pfam13877  81 LAVMFLSKAEK 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
126-372 4.75e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 101.62  E-value: 4.75e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYS 205
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 206 RRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqieaqqnkqqaise 285
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNL-------------------------------------------- 116

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 286 kdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGK 365
Cdd:COG0457  117 ---GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193


                 ....*..
gi 225735591 366 LNEAKQD 372
Cdd:COG0457  194 EVLLALL 200
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-374 7.38e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 100.85  E-value: 7.38e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 163 DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELr 242
Cdd:COG0457    4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 243 kisqalaskensypkeadivikstegerkqieaqqnkqqaisekdrGNGFFKEGKYERAIECYTRGIAADGANALLPANR 322
Cdd:COG0457   83 ----------------------------------------------GLALQALGRYEEALEDYDKALELDPDDAEALYNL 116

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 225735591 323 AMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFE 374
Cdd:COG0457  117 GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 133-383 2.20e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.41  E-value: 2.20e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARF 212
Cdd:COG2956    8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 213 ALQKLEEAKKDYERVLELEPNNFEATNELRKISQalasKENSYPKEADIVikstegeRKQIEAQQNKQQAISEKdrGNGF 292
Cdd:COG2956   88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYE----QEGDWEKAIEVL-------ERLLKLGPENAHAYCEL--AELY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQD 372
Cdd:COG2956  155 LEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234

                        250
                 ....*....|.
gi 225735591 373 FETVLLLEPGN 383
Cdd:COG2956  235 LRKALELDPSD 245
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
194-397 1.15e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 91.61  E-value: 1.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 194 VALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqi 273
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL-------------------------------- 48

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 274 eaqqnkqqaisekdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAF 353
Cdd:COG0457   49 ---------------GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEAL 113

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 225735591 354 ARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397
Cdd:COG0457  114 YNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
126-336 9.31e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 83.13  E-value: 9.31e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYS 205
Cdd:COG0457   35 LELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALY 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 206 RRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 285
Cdd:COG0457  115 NLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 225735591 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAE 336
Cdd:COG0457  195 VLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
131-310 6.14e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 77.26  E-value: 6.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAA 210
Cdd:COG4785   71 DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 211 RFALQKLEEAKKDYERVLELEPNNFEatnelRKISQALAskensypkeadivikstEGERKQIEAQQNKQQAIsekdrGN 290
Cdd:COG4785  151 LYYLGRYELAIADLEKALELDPNDPE-----RALWLYLA-----------------ERKLDPEKALALLLEDW-----AT 203

                        170       180
                 ....*....|....*....|
gi 225735591 291 GFFKEGKYERAIECYTRGIA 310
Cdd:COG4785  204 AYLLQGDTEEARELFKLALA 223
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 133-337 1.18e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 80.81  E-value: 1.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARF 212
Cdd:COG3914   78 AALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALR 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 213 ALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqieaqqnkqqaisekdrGNGF 292
Cdd:COG3914  158 RLGRLEEAIAALRRALELDPDNAEALNNL-----------------------------------------------GNAL 190

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 225735591 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEK 337
Cdd:COG3914  191 QDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR 235
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 129-377 4.35e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.92  E-value: 4.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRG 208
Cdd:COG2956   72 DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELA 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 209 AARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeADIvikstegerkqieaqqnkqqaisekdr 288
Cdd:COG2956  152 ELYLEQGDYDEAIEALEKALKLDPDCARALLLL-----------------AEL--------------------------- 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 289 gngFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFArrgtartfLGKLNE 368
Cdd:COG2956  188 ---YLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA--------LADLLE 256


                 ....*....
gi 225735591 369 AKQDFETVL 377
Cdd:COG2956  257 RKEGLEAAL 265
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
203-381 5.14e-15

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 74.57  E-value: 5.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 203 AYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEgerkqieAQQNKQQA 282
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDR-------ALALPDLA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 283 ISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
Cdd:COG4785   74 QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYY 153

                        170
                 ....*....|....*....
gi 225735591 363 LGKLNEAKQDFETVLLLEP 381
Cdd:COG4785  154 LGRYELAIADLEKALELDP 172
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 136-267 1.16e-14

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 75.98  E-value: 1.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 136 LKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
Cdd:PLN03088   5 LEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLE 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 225735591 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTE 267
Cdd:PLN03088  85 EYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEEKDLVQPVPSDLPSSV 136
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 90-232 1.80e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 71.53  E-value: 1.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  90 YEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVL 169
Cdd:COG5010   11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 225735591 170 PTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 140-247 2.08e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 70.42  E-value: 2.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 140 GNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                         90       100
                 ....*....|....*....|....*...
gi 225735591 220 AKKDYERVLELEPNNFEATNELRKISQA 247
Cdd:COG4235  104 AIAAWQKLLALLPADAPARLLEASIAEA 131
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 293-431 7.85e-14

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 73.28  E-value: 7.85e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQD 372
Cdd:PLN03088  13 FVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAA 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 225735591 373 FETVLLLEPGN---KQAVTELS-KIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKP 431
Cdd:PLN03088  93 LEKGASLAPGDsrfTKLIKECDeKIAEEEKDLVQPVPSDLPSSVTAPPVEEADATPVVPPSKP 155
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 133-383 1.32e-13

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 73.86  E-value: 1.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPyNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAA-- 210
Cdd:TIGR00990 127 AAKLKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAyd 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  211 -----------------------------------RFALQKLEEAKKDYERVL---------------ELEPNNFEATNE 240
Cdd:TIGR00990 206 glgkyadalldltasciidgfrneqsaqaverllkKFAESKAKEILETKPENLpsvtfvgnylqsfrpKPRPAGLEDSNE 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  241 LRK---ISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQ-QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANA 316
Cdd:TIGR00990 286 LDEetgNGQLQLGLKSPESKADESYEEAARAFEKALDLGKLGEkEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVT 365

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 225735591  317 LLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383
Cdd:TIGR00990 366 QSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDF 432
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 130-252 4.75e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.75  E-value: 4.75e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGA 209
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 225735591 210 ARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
Cdd:COG4783   81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPD 123
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 129-234 5.88e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.37  E-value: 5.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRG 208
Cdd:COG4783   34 DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLA 113

                         90       100
                 ....*....|....*....|....*.
gi 225735591 209 AARFALQKLEEAKKDYERVLELEPNN 234
Cdd:COG4783  114 RAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 126-248 3.36e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 3.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYS 205
Cdd:COG2956  103 LELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 225735591 206 RRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
Cdd:COG2956  183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
143-233 5.42e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.11  E-value: 5.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 143 YFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAEsDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 222
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|.
gi 225735591 223 DYERVLELEPN 233
Cdd:COG3063   81 YLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 173-356 5.57e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.87  E-value: 5.57e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaske 252
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL----------- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 253 nsypkeadivikstegerkqieaqqnkqqaisekdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKY 332
Cdd:COG3914  153 ------------------------------------GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRL 196

                        170       180
                 ....*....|....*....|....
gi 225735591 333 EEAEKDCTQAILLDGSYSKAFARR 356
Cdd:COG3914  197 EEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 203-383 9.42e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.90  E-value: 9.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 203 AYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIsqalaskensypkeadivikstegerkqieaqqnkqqa 282
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEI-------------------------------------- 47

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 283 isekdrgngFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
Cdd:COG4783   48 ---------LLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRA 118

                        170       180
                 ....*....|....*....|.
gi 225735591 363 LGKLNEAKQDFETVLLLEPGN 383
Cdd:COG4783  119 LGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 209-386 2.40e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.94  E-value: 2.40e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 209 AARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEkDR 288
Cdd:COG3914    6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLE-LA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 289 GNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNE 368
Cdd:COG3914   85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                        170
                 ....*....|....*...
gi 225735591 369 AKQDFETVLLLEPGNKQA 386
Cdd:COG3914  165 AIAALRRALELDPDNAEA 182
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 247-381 2.62e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 62.29  E-value: 2.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 247 ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAY 326
Cdd:COG5010   19 KLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLY 98

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 225735591 327 LKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP 381
Cdd:COG5010   99 SRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 173-346 4.91e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 4.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaske 252
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNL----------- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 253 nsypkeadivikstegerkqieaqqnkqqaisekdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKY 332
Cdd:COG4783   79 ------------------------------------GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRP 122

                        170
                 ....*....|....
gi 225735591 333 EEAEKDCTQAILLD 346
Cdd:COG4783  123 DEAIAALEKALELD 136
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 280-397 7.16e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.59  E-value: 7.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTA 359
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 225735591 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRAL 119
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 202-386 2.53e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 2.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqieaqqnkqq 281
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNL---------------------------------------- 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 282 aisekdrGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTART 361
Cdd:COG3914  119 -------GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                        170       180
                 ....*....|....*....|....*
gi 225735591 362 FLGKLNEAKQDFETVLLLEPGNKQA 386
Cdd:COG3914  192 DLGRLEEAIAAYRRALELDPDNADA 216
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 289-388 3.82e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.09  E-value: 3.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 289 GNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNE 368
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                         90       100
                 ....*....|....*....|
gi 225735591 369 AKQDFETVLLLEPGNKQAVT 388
Cdd:COG4235  104 AIAAWQKLLALLPADAPARL 123
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 247-400 4.87e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 62.69  E-value: 4.87e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  247 ALASKENSYPKEADIVIKSTEGE-----RKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADgANALLPAN 321
Cdd:TIGR00990  87 KTEEKKSTAPKNAPVEPADELPEidessVANLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECK-PDPVYYSN 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  322 RAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFeTVLLLEPG--------------NKQAV 387
Cdd:TIGR00990 166 RAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDL-TASCIIDGfrneqsaqaverllKKFAE 244

                         170
                  ....*....|...
gi 225735591  388 TELSKIKKELIEK 400
Cdd:TIGR00990 245 SKAKEILETKPEN 257
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 132-386 6.78e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.41  E-value: 6.78e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  132 KALVLKekGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAAR 211
Cdd:TIGR02917 194 DALLLK--GDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  212 FALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVikstegerKQIEAQQN--KQQAISEkdrg 289
Cdd:TIGR02917 272 FQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQIL--------KYAPNSHQarRLLASIQ---- 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  290 ngfFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEA 369
Cdd:TIGR02917 340 ---LRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEA 416

                         250
                  ....*....|....*..
gi 225735591  370 KQDFETVLLLEPGNKQA 386
Cdd:TIGR02917 417 IADLETAAQLDPELGRA 433
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 126-234 2.68e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 2.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYS 205
Cdd:COG2956  137 LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP 216

                         90       100
                 ....*....|....*....|....*....
gi 225735591 206 RRGAARFALQKLEEAKKDYERVLELEPNN 234
Cdd:COG2956  217 RLAELYEKLGDPEEALELLRKALELDPSD 245
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 140-394 8.64e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.94  E-value: 8.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  140 GNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  220 AKKDYERVLELEPNN----------FEATNELRKISQAL--ASKENSYPKEADIVIKSTegerkqieaqqnkqqaisekd 287
Cdd:TIGR02917 382 AAEYLAKATELDPENaaartqlgisKLSQGDPSEAIADLetAAQLDPELGRADLLLILS--------------------- 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  288 rgngFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLN 367
Cdd:TIGR02917 441 ----YLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPD 516

                         250       260
                  ....*....|....*....|....*..
gi 225735591  368 EAKQDFETVLLLEPGNKQAVTELSKIK 394
Cdd:TIGR02917 517 DAIQRFEKVLTIDPKNLRAILALAGLY 543
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 143-390 9.49e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 9.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  143 YFKQGKYDEAIDCYT-KGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRsyTKAYSRRGAARFALQ--KLEE 219
Cdd:TIGR02917 100 YLLQGKFQQVLDELPgKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDP--RSLYAKLGLAQLALAenRFDE 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  220 AKKDYERVLELEP-----------------NNFEATNELRKISQALASKENSYPKEADIVIKSTEGE--RKQIEA--QQN 278
Cdd:TIGR02917 178 ARALIDEVLTADPgnvdalllkgdlllslgNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEeaEKHADAllKKA 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  279 KQQAISEKDRGNGFFKEGKYERAIECYTRG--IAADGANALL------------------------------PANR--AM 324
Cdd:TIGR02917 258 PNSPLAHYLKALVDFQKKNYEDARETLQDAlkSAPEYLPALLlagaseyqlgnleqayqylnqilkyapnshQARRllAS 337

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 225735591  325 AYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTEL 390
Cdd:TIGR02917 338 IQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQL 403
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
292-381 1.13e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.87  E-value: 1.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 292 FFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKdCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQ 371
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|
gi 225735591 372 DFETVLLLEP 381
Cdd:COG3063   81 YLERALELDP 90
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
315-386 1.28e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.69  E-value: 1.28e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 225735591 315 NALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386
Cdd:COG4785   72 LAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA 143
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
166-346 2.51e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.92  E-value: 2.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 166 NPVLPTNRASAYFRLKKFAVAESDCNLA------VALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATN 239
Cdd:COG4785   32 AAVLALAIALADLALALAAAALAAAALAaeridrALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYN 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 240 elrkisqalaskensypkeadivikstegerkqieaqqnkqqaisekDRGNGFFKEGKYERAIECYTRGIAAD--GANAL 317
Cdd:COG4785  112 -----------------------------------------------NRGLAYLLLGDYDAALEDFDRALELDpdYAYAY 144

                        170       180
                 ....*....|....*....|....*....
gi 225735591 318 LpaNRAMAYLKIQKYEEAEKDCTQAILLD 346
Cdd:COG4785  145 L--NRGIALYYLGRYELAIADLEKALELD 171
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 289-404 3.30e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 3.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 289 GNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNE 368
Cdd:COG2956   49 GNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK 128

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 225735591 369 AKQDFETVLLLEPGNKQAVTELSKIkkeLIEKGHWD 404
Cdd:COG2956  129 AIEVLERLLKLGPENAHAYCELAEL---YLEQGDYD 161
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 300-386 6.40e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 6.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 300 RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLL 379
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*..
gi 225735591 380 EPGNKQA 386
Cdd:COG4235   81 DPDNPEA 87
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 151-237 7.33e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 7.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 151 EAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLEL 230
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*..
gi 225735591 231 EPNNFEA 237
Cdd:COG4235   81 DPDNPEA 87
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 133-374 1.53e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 54.60  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARF 212
Cdd:TIGR00990 331 AIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHF 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  213 ALQKLEEAKKDYERVLELEPNNFEATNELrkisQALASKENSYpkeADIVIKSTEGERKQIEAQQNKQQAisekdrGNGF 292
Cdd:TIGR00990 411 IKGEFAQAGKDYQKSIDLDPDFIFSHIQL----GVTQYKEGSI---ASSMATFRRCKKNFPEAPDVYNYY------GELL 477

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  293 FKEGKYERAIECYTRGIAADG------ANALLPANRAMAYLK-IQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGK 365
Cdd:TIGR00990 478 LDQNKFDEAIEKFDTAIELEKetkpmyMNVLPLINKALALFQwKQDFIEAENLCEKALIIDPECDIAVATMAQLLLQQGD 557


                  ....*....
gi 225735591  366 LNEAKQDFE 374
Cdd:TIGR00990 558 VDEALKLFE 566
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 140-239 3.17e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.46  E-value: 3.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 140 GNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEV 232

                         90       100
                 ....*....|....*....|
gi 225735591 220 AKKDYERVLELEPNNFEATN 239
Cdd:COG3914  233 YDRFEELLAALARGPSELSP 252
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 143-391 4.47e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.16  E-value: 4.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  143 YFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 222
Cdd:TIGR02917 543 YLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVS 622

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  223 DYERVLELEPNNFEATNELRKISQ--------------ALASKENSYpkEADIVIKSTEGERKQIEA---------QQNK 279
Cdd:TIGR02917 623 SFKKLLALQPDSALALLLLADAYAvmknyakaitslkrALELKPDNT--EAQIGLAQLLLAAKRTESakkiakslqKQHP 700

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGaNALLPANRAMAYLKIQKYEEAEKDCTQailldgsYSKAFARRGTA 359
Cdd:TIGR02917 701 KAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP-SSQNAIKLHRALLASGNTAEAVKTLEA-------WLKTHPNDAVL 772

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 225735591  360 RTFLG-------KLNEAKQDFETVLLLEPGNKQAVTELS 391
Cdd:TIGR02917 773 RTALAelylaqkDYDKAIKHYQTVVKKAPDNAVVLNNLA 811
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 161-346 1.28e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.80  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 161 DADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240
Cdd:COG5010   14 LLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 241 LrkisqalaskensypkeadivikstegerkqieaqqnkqqaisekdrGNGFFKEGKYERAIECYTRGIAADGANALLPA 320
Cdd:COG5010   94 L-----------------------------------------------ALLYSRSGDKDEAKEYYEKALALSPDNPNAYS 126

                        170       180
                 ....*....|....*....|....*.
gi 225735591 321 NRAMAYLKIQKYEEAEKDCTQAILLD 346
Cdd:COG5010  127 NLAALLLSLGQDDEAKAALQRALGTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
176-241 1.53e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 1.53e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 225735591 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKdYERVLELEPNNFEATNEL 241
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNL 65
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 313-405 1.85e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 1.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 313 GANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSK 392
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                         90
                 ....*....|...
gi 225735591 393 IkkeLIEKGHWDD 405
Cdd:COG4783   81 A---LLKAGDYDE 90
TPR_1 pfam00515
Tetratricopeptide repeat;
202-234 2.05e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 44.72  E-value: 2.05e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 225735591  202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNN 234
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 307-404 3.28e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 3.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 307 RGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386
Cdd:COG5010   45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNA 124

                         90
                 ....*....|....*...
gi 225735591 387 VTELSKIkkeLIEKGHWD 404
Cdd:COG5010  125 YSNLAAL---LLSLGQDD 139
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 142-247 5.94e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.75  E-value: 5.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 142 KYFKQGKYDEAIDCYTKGMDADPYNPVLPT---NRASAYFRLKKFAVAESDCNLAVALNRSYTK---AYSRRGAARFALQ 215
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELG 81

                         90       100       110
                 ....*....|....*....|....*....|..
gi 225735591 216 KLEEAKKDYERVLELEPNNFEATNELRKISQA 247
Cdd:COG1729   82 DYDKARATLEELIKKYPDSEAAKEARARLARL 113
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 133-166 9.02e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.82  E-value: 9.02e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 225735591   133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN 166
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
133-166 1.74e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.02  E-value: 1.74e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 225735591  133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN 166
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 140-338 4.60e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 4.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  140 GNKYFKQGKYDEAIDCYTK----GMDADPYNPVLptnrASAYFRLKKF--AVAESDcNLAVALNRSYTKAYSRRGAARFA 213
Cdd:TIGR02917  63 GKIYLALGDYAAAEKELRKalslGYPKNQVLPLL----ARAYLLQGKFqqVLDELP-GKTLLDDEGAAELLALRGLAYLG 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  214 LQKLEEAKKDYERVLELEPNNFEAtnelrKISQA-LASKENSYPKEADIVIKSTEGERKQIEAQQNKqqaisekdrGNGF 292
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYA-----KLGLAqLALAENRFDEARALIDEVLTADPGNVDALLLK---------GDLL 203

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 225735591  293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKD 338
Cdd:TIGR02917 204 LSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH 249
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
325-397 5.44e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 5.44e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 225735591 325 AYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQdFETVLLLEPGNKQAVTELSKIKKEL 397
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 202-234 6.88e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.12  E-value: 6.88e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 225735591   202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNN 234
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_11 pfam13414
TPR repeat;
140-180 7.77e-05

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.15  E-value: 7.77e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 225735591  140 GNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
126-199 1.69e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.69e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 225735591 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDcYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRS 199
Cdd:COG3063   19 LELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 202-233 1.94e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.04  E-value: 1.94e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 225735591  202 KAYSRRGAARFALQKLEEAKKDYERVLELEPN 233
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 163-335 3.96e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 42.32  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  163 DPYNPVLPTNRASA----------YFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232
Cdd:TIGR02521  17 DVPRSSRTTDRNKAakirvqlalgYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  233 NNFEATN-------ELRKISQALASKEnsypkeadivikstegerKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECY 305
Cdd:TIGR02521  97 NNGDVLNnygtflcQQGKYEQAMQQFE------------------QAIEDPLYPQPARSLENAGLCALKAGDFDKAEKYL 158

                         170       180       190
                  ....*....|....*....|....*....|..
gi 225735591  306 TRGIAADGANAllPANRAMA--YLKIQKYEEA 335
Cdd:TIGR02521 159 TRALQIDPQRP--ESLLELAelYYLRGQYKDA 188
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
210-348 6.42e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 6.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 210 ARFALQKLEEAKKDYERVLELEPNNFEATNELrkisqalaskensypkeadivikstegerkqieaqqnkqqaisekdrG 289
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNL-----------------------------------------------G 33

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 225735591 290 NGFFKEGKYERAIEcYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 348
Cdd:COG3063   34 LLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 274-405 7.13e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 7.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 274 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQK---YEEAEKDCTQAILLDGSYS 350
Cdd:COG3914   33 EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQAlgrYEEALALYRRALALNPDNA 112

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 225735591 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIkkeLIEKGHWDD 405
Cdd:COG3914  113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEA---LRRLGRLEE 164
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 193-337 8.86e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 8.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNfeatnelrkiSQALAskensypkeadivikstegerkq 272
Cdd:COG4235    9 ALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN----------ADALL----------------------- 55

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 225735591 273 ieaqqnkqqaisekDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEK 337
Cdd:COG4235   56 --------------DLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIA 106
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 133-164 1.16e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 36.73  E-value: 1.16e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 225735591  133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADP 164
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
321-349 1.19e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.63  E-value: 1.19e-03
                          10        20
                  ....*....|....*....|....*....
gi 225735591  321 NRAMAYLKIQKYEEAEKDCTQAILLDGSY 349
Cdd:pfam00515   6 NLGNAYFKLGKYDEALEYYEKALELNPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 292-395 1.90e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.43  E-value: 1.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591 292 FFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSK---AFARRGTARTFLGK 365
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGD 82

                         90       100       110
                 ....*....|....*....|....*....|
gi 225735591 366 LNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
Cdd:COG1729   83 YDKARATLEELIKKYPDSEAAKEARARLAR 112
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 129-393 1.99e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKA----- 203
Cdd:TIGR02917 359 DPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRAdllli 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  204 -----------------------------YSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQalaskens 254
Cdd:TIGR02917 439 lsylrsgqfdkalaaakklekkqpdnaslHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI-------- 510

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225735591  255 ypKEADIVIKSTEGERKQIEAQQNKQ--QAISEKdrgngFFKEGKYERAIECYTRGIAADganallPANRAMAYLKIQKY 332
Cdd:TIGR02917 511 --QEGNPDDAIQRFEKVLTIDPKNLRaiLALAGL-----YLRTGNEEEAVAWLEKAAELN------PQEIEPALALAQYY 577

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 225735591  333 EEaEKDCTQAILLDGSYSK-------AFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKI 393
Cdd:TIGR02917 578 LG-KGQLKKALAILNEAADaapdspeAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADA 644
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 321-349 5.52e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 5.52e-03
                           10        20
                   ....*....|....*....|....*....
gi 225735591   321 NRAMAYLKIQKYEEAEKDCTQAILLDGSY 349
Cdd:smart00028   6 NLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_11 pfam13414
TPR repeat;
289-328 6.71e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 34.75  E-value: 6.71e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 225735591  289 GNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLK 328
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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