|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
267-770 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 788.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 267 KTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGR--CHTTHSMALIHNRS 344
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPreCQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 345 LFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPirVNPRVSNVKSVYK--THIDVIHYR 422
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVKGLPVfaTYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 423 KTDAKRLHGLDEEAEQKlFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGrgKFRA 502
Cdd:smart00350 159 KLDYKRSFEDSSFSVQS-LSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGM--KIRG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 503 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNES 582
Cdd:smart00350 236 DINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 583 TRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRL 662
Cdd:smart00350 316 DRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDREL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 663 AHHLVALYYQS---EEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYP---RQLES 736
Cdd:smart00350 396 AKHVVDLHRYShpeEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTESRSSIPitvRQLES 475
|
490 500 510
....*....|....*....|....*....|....
gi 33469919 737 LIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALK 770
Cdd:smart00350 476 IIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
163-850 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 626.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 163 KENFQRFLQRFIdplakeeenvgiditeplYMQRLGEI--NVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMA 240
Cdd:COG1241 6 VDKFEEFLRRYK------------------YRDEILELaqEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 241 VNEIffDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRG 320
Cdd:COG1241 68 LREI--DLEPYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 321 RIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIR 400
Cdd:COG1241 146 KLQEPHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRT 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 401 VnprvSNVKS-VYKTHIDVIHYRKTDaKRLhgldEEAEqklFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKG 479
Cdd:COG1241 226 S----GRGKStIFDLYLEANSIEVEE-KEF----EEIE---ITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEA 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 480 ILLQLFGGTRK---DFSHTgrgkfRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE-TRQ 555
Cdd:COG1241 294 IALQLFGGVPKvlpDGSRI-----RGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 556 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQ 635
Cdd:COG1241 369 WTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQID 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 636 LPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAV---------LKDYIAYAHSTIMPRLSEEA 706
Cdd:COG1241 449 LPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGELLEQEIEEETEEvkpeidpdlLRKYIAYARRNVFPVLTEEA 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 707 SQALIEAYVDMRKIGSS-RGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISI 785
Cdd:COG1241 529 KDLIEDFYVDMRKKGEDeDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDV 608
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33469919 786 LTTGMSATSRKRKEELAEALKKLiLSKGKTPAlKYQQLFEDIRGQsdiAITKDMFEEALRALADD 850
Cdd:COG1241 609 IETGTSKSQRDKMKLIKDIIKEL-EEESSGGA-PIEDVIEEAEEE---GIDREKAEELIEKLKRK 668
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
461-768 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 599.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFsHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDF-TKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 620
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQS-EEQAEEELLDMAVLKDYIAYAHSTIM 699
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDtPEHIQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 700 PRLSEEASQALIEAYVDMRKIGSS-RGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
163-847 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 570.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 163 KENFQRFLQRFIDPLAKEEenvgiditeplYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVN 242
Cdd:NF040949 2 GEKFKEFIRTFRDSFGNEK-----------YKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 243 EIFFDRYPDSILEHQ-IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRV----EM 317
Cdd:NF040949 71 EIVEEEDPEYAEEVAkFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWpeeeEE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 318 DRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAV 397
Cdd:NF040949 151 SYEIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 398 PIRVNPRvsNVKSVYKTHIDVIHYrktdakrlhgldeEAEQKLF-----SEKRVELLKELSRKPDIYERLASALAPSIYE 472
Cdd:NF040949 231 PDSSLKK--GSRPIFKNYIEANHI-------------EVSQKELeeveiTEEDEEKILELAKDPWIREKIIASIAPSIYG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 473 HEDIKKGILLQLFGGTRKDFSHTGRgkFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE 552
Cdd:NF040949 296 HWEIKEAIALLLFGGVPKVLPDGTR--IRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 553 TRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIE 632
Cdd:NF040949 374 TGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAE 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 633 NIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYyqSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 712
Cdd:NF040949 454 NIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH--SGKEKVKPEIDPDLLKKYIAYARKYVRPKLTEEAKKLIED 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 713 AYVDMRK-IGSSRGMVSAYP---RQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTT 788
Cdd:NF040949 532 FYVEMRKsSKSSEDPDSPIPitaRQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMT 611
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 33469919 789 GMSATSRKRKEELAEALKKLILSKGKTPalkyqqLFEDIRGQSDIAITKDMFEEALRAL 847
Cdd:NF040949 612 GKPKSKREKMSKIVEIIKELEEEEECVK------IKELIKEAEKKGIDEEKVEELISDL 664
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
156-847 |
1.48e-163 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 499.91 E-value: 1.48e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 156 DVNVAACKENFQRFLQRFI---DPLAKEEENVGI-DITEPLYMQRLgeINVIGE-------------PFlNVNCEHIKSF 218
Cdd:PTZ00111 82 DNRLEELSERFTNFLKNFTefsDVLEFKDEQQSKpEYTELYYLWKL--MNFIKEnlrdhstgysrilPF-EVDLMHVYSF 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 219 DKNLYRQLISYPQEVIPTFDMAV----NEIFFDRYPDSILEHQI---QVRPFNALKTKNMRNLNPEDIDQLITISGMVIR 291
Cdd:PTZ00111 159 DKVLYKLLVTFPADCIAELDKVLvklfNELLSKHYSDLSLENNSffpRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVR 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 292 TSQLIPEMQEAFFQC-----------QVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPED 360
Cdd:PTZ00111 239 QTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQGEVNEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSS 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 361 MPAGQTP--------------------HTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIH 420
Cdd:PTZ00111 319 LNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIH 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 421 YR---KTDAKR-LHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGG--TRKDFSH 494
Cdd:PTZ00111 399 VKvinSTNANQpEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGnkNSSDFNK 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 495 TGRG-----KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYV-MKDPETRQLVLQTGALVLSDN 568
Cdd:PTZ00111 479 SPDAcykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANG 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 569 GICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIF 648
Cdd:PTZ00111 559 GVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIY 638
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 649 LLLDPQDE---------------------------AYDRRLAHHLVALYYQSEEQAEEELLDMavLKDYIAYAHSTIMPR 701
Cdd:PTZ00111 639 LVLDHIDQdtdqlislsiakdfllphmtgsgndedTYDRSNTMHVEDESLRSEKDYNKNDLDM--LRMYIKFSKLHCFPK 716
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 702 LSEEASQALIEAYVDMRKIG------------------------SSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAID 757
Cdd:PTZ00111 717 LSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPAD 796
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 758 VEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQL----------FEDI 827
Cdd:PTZ00111 797 ALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSVLTRSSNQDSNKSLDLnevlslchktFKDN 876
|
810 820
....*....|....*....|
gi 33469919 828 RGQSDIAITKdMFEEALRAL 847
Cdd:PTZ00111 877 RDHKDGEIYK-LISEVLNKM 895
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
445-670 |
6.74e-136 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 403.45 E-value: 6.74e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 445 RVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKdfSHTGRGKFRAEINILLCGDPGTSKSQLLQYVY 524
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKK--ILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 525 NLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGII 604
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33469919 605 CQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALY 670
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
163-264 |
1.19e-18 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 81.57 E-value: 1.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 163 KENFQRFLQRFidplaKEEENvgidiTEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVN 242
Cdd:pfam14551 1 KRKFKDFLEEF-----REDGD-----GEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALK 70
|
90 100
....*....|....*....|....*
gi 33469919 243 EIFFDRYPDS---ILEHQIQVRPFN 264
Cdd:pfam14551 71 EVVKELSEDPdyaEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
267-770 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 788.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 267 KTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGR--CHTTHSMALIHNRS 344
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPreCQSPTPFSLNHERS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 345 LFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPirVNPRVSNVKSVYK--THIDVIHYR 422
Cdd:smart00350 81 TFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP--YGFKLNTVKGLPVfaTYIEANHVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 423 KTDAKRLHGLDEEAEQKlFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGrgKFRA 502
Cdd:smart00350 159 KLDYKRSFEDSSFSVQS-LSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGM--KIRG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 503 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNES 582
Cdd:smart00350 236 DINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 583 TRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRL 662
Cdd:smart00350 316 DRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDREL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 663 AHHLVALYYQS---EEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYP---RQLES 736
Cdd:smart00350 396 AKHVVDLHRYShpeEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEDSQTESRSSIPitvRQLES 475
|
490 500 510
....*....|....*....|....*....|....
gi 33469919 737 LIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALK 770
Cdd:smart00350 476 IIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
163-850 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 626.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 163 KENFQRFLQRFIdplakeeenvgiditeplYMQRLGEI--NVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMA 240
Cdd:COG1241 6 VDKFEEFLRRYK------------------YRDEILELaqEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 241 VNEIffDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRG 320
Cdd:COG1241 68 LREI--DLEPYDVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 321 RIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIR 400
Cdd:COG1241 146 KLQEPHECPGCGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRT 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 401 VnprvSNVKS-VYKTHIDVIHYRKTDaKRLhgldEEAEqklFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKG 479
Cdd:COG1241 226 S----GRGKStIFDLYLEANSIEVEE-KEF----EEIE---ITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEA 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 480 ILLQLFGGTRK---DFSHTgrgkfRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE-TRQ 555
Cdd:COG1241 294 IALQLFGGVPKvlpDGSRI-----RGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFgTGR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 556 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQ 635
Cdd:COG1241 369 WTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQID 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 636 LPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAV---------LKDYIAYAHSTIMPRLSEEA 706
Cdd:COG1241 449 LPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGELLEQEIEEETEEvkpeidpdlLRKYIAYARRNVFPVLTEEA 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 707 SQALIEAYVDMRKIGSS-RGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISI 785
Cdd:COG1241 529 KDLIEDFYVDMRKKGEDeDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFDIDV 608
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33469919 786 LTTGMSATSRKRKEELAEALKKLiLSKGKTPAlKYQQLFEDIRGQsdiAITKDMFEEALRALADD 850
Cdd:COG1241 609 IETGTSKSQRDKMKLIKDIIKEL-EEESSGGA-PIEDVIEEAEEE---GIDREKAEELIEKLKRK 668
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
461-768 |
0e+00 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 599.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFsHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDF-TKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 620
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQS-EEQAEEELLDMAVLKDYIAYAHSTIM 699
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDtPEHIQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 700 PRLSEEASQALIEAYVDMRKIGSS-RGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKMGSDaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
163-847 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 570.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 163 KENFQRFLQRFIDPLAKEEenvgiditeplYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVN 242
Cdd:NF040949 2 GEKFKEFIRTFRDSFGNEK-----------YKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 243 EIFFDRYPDSILEHQ-IQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRV----EM 317
Cdd:NF040949 71 EIVEEEDPEYAEEVAkFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWpeeeEE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 318 DRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAV 397
Cdd:NF040949 151 SYEIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 398 PIRVNPRvsNVKSVYKTHIDVIHYrktdakrlhgldeEAEQKLF-----SEKRVELLKELSRKPDIYERLASALAPSIYE 472
Cdd:NF040949 231 PDSSLKK--GSRPIFKNYIEANHI-------------EVSQKELeeveiTEEDEEKILELAKDPWIREKIIASIAPSIYG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 473 HEDIKKGILLQLFGGTRKDFSHTGRgkFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPE 552
Cdd:NF040949 296 HWEIKEAIALLLFGGVPKVLPDGTR--IRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 553 TRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIE 632
Cdd:NF040949 374 TGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAE 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 633 NIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYyqSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 712
Cdd:NF040949 454 NIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVH--SGKEKVKPEIDPDLLKKYIAYARKYVRPKLTEEAKKLIED 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 713 AYVDMRK-IGSSRGMVSAYP---RQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTT 788
Cdd:NF040949 532 FYVEMRKsSKSSEDPDSPIPitaRQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIDVETGKIDIDTIMT 611
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 33469919 789 GMSATSRKRKEELAEALKKLILSKGKTPalkyqqLFEDIRGQSDIAITKDMFEEALRAL 847
Cdd:NF040949 612 GKPKSKREKMSKIVEIIKELEEEEECVK------IKELIKEAEKKGIDEEKVEELISDL 664
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
156-847 |
1.48e-163 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 499.91 E-value: 1.48e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 156 DVNVAACKENFQRFLQRFI---DPLAKEEENVGI-DITEPLYMQRLgeINVIGE-------------PFlNVNCEHIKSF 218
Cdd:PTZ00111 82 DNRLEELSERFTNFLKNFTefsDVLEFKDEQQSKpEYTELYYLWKL--MNFIKEnlrdhstgysrilPF-EVDLMHVYSF 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 219 DKNLYRQLISYPQEVIPTFDMAV----NEIFFDRYPDSILEHQI---QVRPFNALKTKNMRNLNPEDIDQLITISGMVIR 291
Cdd:PTZ00111 159 DKVLYKLLVTFPADCIAELDKVLvklfNELLSKHYSDLSLENNSffpRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVR 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 292 TSQLIPEMQEAFFQC-----------QVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPED 360
Cdd:PTZ00111 239 QTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQGEVNEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSS 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 361 MPAGQTP--------------------HTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIH 420
Cdd:PTZ00111 319 LNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIH 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 421 YR---KTDAKR-LHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGG--TRKDFSH 494
Cdd:PTZ00111 399 VKvinSTNANQpEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGnkNSSDFNK 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 495 TGRG-----KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYV-MKDPETRQLVLQTGALVLSDN 568
Cdd:PTZ00111 479 SPDAcykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANG 558
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 569 GICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIF 648
Cdd:PTZ00111 559 GVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIY 638
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 649 LLLDPQDE---------------------------AYDRRLAHHLVALYYQSEEQAEEELLDMavLKDYIAYAHSTIMPR 701
Cdd:PTZ00111 639 LVLDHIDQdtdqlislsiakdfllphmtgsgndedTYDRSNTMHVEDESLRSEKDYNKNDLDM--LRMYIKFSKLHCFPK 716
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 702 LSEEASQALIEAYVDMRKIG------------------------SSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAID 757
Cdd:PTZ00111 717 LSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPAD 796
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 758 VEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQL----------FEDI 827
Cdd:PTZ00111 797 ALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQMYEQVLSVLTRSSNQDSNKSLDLnevlslchktFKDN 876
|
810 820
....*....|....*....|
gi 33469919 828 RGQSDIAITKdMFEEALRAL 847
Cdd:PTZ00111 877 RDHKDGEIYK-LISEVLNKM 895
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
461-768 |
2.18e-137 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 410.97 E-value: 2.18e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFShtGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILE--DGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 620
Cdd:cd17706 79 AGLTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALY------YQSEEQAEEELLDMAVLKDYIAYA 694
Cdd:cd17706 159 GGRYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHrgsdpeEQVKPEEDGIPIDIELLRKYILYA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 33469919 695 hSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768
Cdd:cd17706 239 -RQIHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
445-670 |
6.74e-136 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 403.45 E-value: 6.74e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 445 RVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKdfSHTGRGKFRAEINILLCGDPGTSKSQLLQYVY 524
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKK--ILPDGTRLRGDINVLLVGDPGTAKSQLLKYVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 525 NLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGII 604
Cdd:pfam00493 79 KIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33469919 605 CQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALY 670
Cdd:pfam00493 159 ATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
461-764 |
1.51e-123 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 374.82 E-value: 1.51e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKdfshTGRG-KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSS 539
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDK----RGDGmKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 540 AVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANP 619
Cdd:cd17758 77 GVGLTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 620 IESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE-ELLDMAVLKDYIAYAhSTI 698
Cdd:cd17758 157 AYGRYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDfEPLDPKLLRAYIALA-KRK 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33469919 699 MPRLSEEASQALIEAYVDMRKiGSSRGMVSAY--PRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRL 764
Cdd:cd17758 236 RPTVPPALADYIVQAYVEMRQ-EAKRSKDFTFttPRTLLAILRLSQALARLRLSDSVEIDDVEEALRL 302
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
461-772 |
1.51e-120 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 367.08 E-value: 1.51e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKdfSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHK--ITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 620
Cdd:cd17757 79 AGLTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALyYQSEEQAEEELLDMAVLKDYIAYAHsTIMP 700
Cdd:cd17757 159 GGRYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDL-HSKREEAIEPPFTAEQLKRYIAYAR-TFKP 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 33469919 701 RLSEEASQALIEAYVDMRKIGSSRGMVSAYP---RQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLhreaLKQS 772
Cdd:cd17757 237 KLTKEAKDELVEQYKELRQDDASGSTRSSYRitvRQLESLIRLSEAIARLHCSDEVTPEHVEEAARL----LKKS 307
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
461-764 |
3.76e-120 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 366.32 E-value: 3.76e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKdfsHTGRG-KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSS 539
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRK---RLPDGmRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 540 AVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANP 619
Cdd:cd17756 78 AAGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 620 IESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEEL----LDMAVLKDYIAYAH 695
Cdd:cd17756 158 VFGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSQEnegeIPISKLKRYIAYCR 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 33469919 696 STIMPRLSEEASQALIEAYVDMRK----IGSSRGMVSAYP---RQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRL 764
Cdd:cd17756 238 AKCAPRLSEEAAEKLSNHYVTIRKdvrqNELESDNRSSIPitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
460-766 |
5.71e-115 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 352.52 E-value: 5.71e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 460 ERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRgkFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSS 539
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTR--IRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGST 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 540 AVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANP 619
Cdd:cd17761 79 AAGLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 620 IESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIM 699
Cdd:cd17761 159 KFGRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPEIDPDLLRKYIAYARKNVR 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33469919 700 PRLSEEASQALIEAYVDMRKIGSSRGM-VSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHR 766
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
462-768 |
4.45e-107 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 331.74 E-value: 4.45e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 462 LASALAPSIYEHEDIKKGILLQLFGGTRKDFshTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAV 541
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNL--ENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 542 GLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIE 621
Cdd:cd17754 80 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 622 SQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQseeqaeeelldMAVLKDYIAYAHSTIMPR 701
Cdd:cd17754 160 GRYDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY-----------IKFLRKYIHYAKERIKPK 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 33469919 702 LSEEASQALIEAYVDMRKIGS----SRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768
Cdd:cd17754 229 LTQEAAEYIAEEYADLRNDDNtktdKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
461-764 |
1.19e-104 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 326.33 E-value: 1.19e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFShtGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPG--GKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 620
Cdd:cd17753 79 VGLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE-------------------EL 681
Cdd:cd17753 159 GGRYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEdregeeeknqrqrpketkvEP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 682 LDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEA 761
Cdd:cd17753 239 IPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMA 318
|
...
gi 33469919 762 KRL 764
Cdd:cd17753 319 IRV 321
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
461-768 |
6.03e-90 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 286.35 E-value: 6.03e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 461 RLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNeSTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPI 620
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMG-SQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHlvalyyqseeqaeeelldMAVLKDYIAYAHSTIMP 700
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH------------------HQLLRKYISYARQYVNP 221
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33469919 701 RLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768
Cdd:cd17759 222 VLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
462-758 |
1.74e-75 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 248.23 E-value: 1.74e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 462 LASALAPSIYEHEDIKKGILLQLFGGT-RKDFSHTgrgKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSA 540
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVqRIDASGT---RVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 541 VGLTAYVMKDpeTRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPi 620
Cdd:cd17760 79 AGLTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 621 ESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHhlVALYYQSEEQAEEELLDMAVLKDYIAYAhSTIMP 700
Cdd:cd17760 156 KGQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISS--FILENKGEPSKSSKLWSMEKMRTYFCLI-KNLRP 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 33469919 701 RLSEEASQALIeAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDV 758
Cdd:cd17760 233 VLSDEANAILL-RYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDA 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
270-398 |
3.21e-54 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 183.45 E-value: 3.21e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 270 NMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVemdrgRIAEPSVCGR--CHTTHSMALIHNRSLFS 347
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGV-----KITEPTKCPNpeCGNKDPFKLVHEKSKFV 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 33469919 348 DKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVP 398
Cdd:pfam17207 76 DFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
687-769 |
1.62e-30 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 114.95 E-value: 1.62e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 687 LKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGS-SRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLH 765
Cdd:pfam17855 3 LRKYIAYAREKIKPKLSEEAREKLVDAYVELRKESTgSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRLL 82
|
....
gi 33469919 766 REAL 769
Cdd:pfam17855 83 KESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
163-264 |
1.19e-18 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 81.57 E-value: 1.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 163 KENFQRFLQRFidplaKEEENvgidiTEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVN 242
Cdd:pfam14551 1 KRKFKDFLEEF-----REDGD-----GEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALK 70
|
90 100
....*....|....*....|....*
gi 33469919 243 EIFFDRYPDS---ILEHQIQVRPFN 264
Cdd:pfam14551 71 EVVKELSEDPdyaEEEKEFQVRFYN 95
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
505-644 |
8.13e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.44 E-value: 8.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 505 NILLCGDPGTSKSQLLQYVYNLVPRGQYTsgkgssAVGLTAYVMKDPETRQLVLQTGALVLSDN---------GICCIDE 575
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVF------YVQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 576 FDKMNESTRSVLHEVMEQQTLSIAKAGIICQL-NARTSVLAAANPIESQWNPkkttieniqLPHTLLSRF 644
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGELVKAaPDGFRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
505-650 |
3.34e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 41.75 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 505 NILLCGDPGTSKSQLLQYVYNLVPRGQYT--SGKGSSAVGLTAYVMKDpETRQLVLQTGALVLSDNGICCIDEFDKMNES 582
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPGAPflYLNASDLLEGLVVAELF-GHFLVRLLFELAEKAKPGVLFIDEIDSLSRG 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 33469919 583 TRSVLHEVMEQQTLSIAKagiicqlNARTSVLAAANPIESqwnpkkttienIQLPHTLLSRFDLIFLL 650
Cdd:cd00009 100 AQNALLRVLETLNDLRID-------RENVRVIGATNRPLL-----------GDLDRALYDRLDIRIVI 149
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
506-770 |
1.67e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 41.31 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 506 ILLCGDPGTSKSQLLQYV-------YNLVprgQYTSG-KGSSAVGLTAYvmkDPETRQLVLQTGAL----VLsdngiccI 573
Cdd:COG0714 34 LLLEGVPGVGKTTLAKALaralglpFIRI---QFTPDlLPSDILGTYIY---DQQTGEFEFRPGPLfanvLL-------A 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 574 DEFDKMNESTRSVLHEVMEQQTLSIAkaGIICQLNARTSVLAAANPIESQwnpkkTTIEniqLPHTLLSRFdLIFLLLDP 653
Cdd:COG0714 101 DEINRAPPKTQSALLEAMEERQVTIP--GGTYKLPEPFLVIATQNPIEQE-----GTYP---LPEAQLDRF-LLKLYIGY 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33469919 654 QDeaydrrlahhlvalyyqseeqAEEELldmAVLKDYIAYAHSTIMPRLSEE---ASQALIEA-YVD-------MRKIGS 722
Cdd:COG0714 170 PD---------------------AEEER---EILRRHTGRHLAEVEPVLSPEellALQELVRQvHVSeavldyiVDLVRA 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 33469919 723 SRGMVSAY----PRQLESLIRLAEAHAKVRLSNKVEAIDVeeaKRLHREALK 770
Cdd:COG0714 226 TREHPDLRkgpsPRASIALLRAARALALLDGRDYVTPDDV---KAVAGPVLK 274
|
|
| |
