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Conserved domains on  [gi|4503759|ref|NP_002013|]
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dimethylaniline monooxygenase [N-oxide-forming] 4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-531 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 1003.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759      2 AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNF 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     82 MNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFP 161
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    162 GIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCS 241
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    242 FIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAK-FIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEEN 320
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKePVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    321 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPP 400
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    401 SQKLMMEATEK-EQLIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKW 479
Cdd:pfam00743 401 QSEMMAEINKRqEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 4503759    480 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMShYLKAWGAPVLLASLLLIC 531
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSF-TLKIFGLPVVLVAIFLIL 531
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-531 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 1003.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759      2 AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNF 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     82 MNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFP 161
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    162 GIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCS 241
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    242 FIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAK-FIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEEN 320
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKePVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    321 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPP 400
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    401 SQKLMMEATEK-EQLIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKW 479
Cdd:pfam00743 401 QSEMMAEINKRqEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 4503759    480 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMShYLKAWGAPVLLASLLLIC 531
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSF-TLKIFGLPVVLVAIFLIL 531
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-395 7.17e-80

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 256.71  E-value: 7.17e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    5 VAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFtesskdgmtRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNH 84
Cdd:COG2072   9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRD---------NRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   85 EKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRpdfSETGQWDVVTETeGKQNRAvfDAVMVCTGHFLNPHLPleAFPGIH 164
Cdd:COG2072  80 DEILAYLEAYADKFGLRRPIRFGTEVTSARWD---EADGRWTVTTDD-GETLTA--RFVVVATGPLSRPKIP--DIPGLE 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  165 KFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGR---SSDWGYPYNMMVTRrccs 241
Cdd:COG2072 152 DFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnyDPERGRPANYLGLE---- 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  242 FIAQVLPSRFLNWIqERKLNKRFNHEDYGL---SITKGKKaKFIVNDELPNCILCGAITMKTSVIE-FTETSAVFEDGTV 317
Cdd:COG2072 228 APPALNRRDARAWL-RRLLRAQVKDPELGLltpDYPPGCK-RPLLSTDYYEALRRGNVELVTGGIErITEDGVVFADGTE 305

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  318 EEnIDVVIFTTGYTFSFPFFEEPlkslctkKIF---------LYKQVFPLNLERatLAIIGLIGLKG--SILSGTELQAR 386
Cdd:COG2072 306 HE-VDVIVWATGFRADLPWLAPL-------DVRgrdgrsgprAYLGVVVPGFPN--LFFLGPNSPSGhsSLTLGAERQAR 375


                ....*....
gi 4503759  387 WVTRVFKGL 395
Cdd:COG2072 376 YIARLIAHM 384
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 2-407 6.58e-41

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 153.86  E-value: 6.58e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     2 AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFT-ESSKDGM----------TRVYKSLVTNVCKEMSCYS 70
Cdd:PLN02172  10 SQHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTpKSESDPLsldptrsivhSSVYESLRTNLPRECMGYR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    71 DFPF-------HEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITkrpdfSETGQWDVVTETEGK-QNRAVFDA 142
Cdd:PLN02172  90 DFPFvprfddeSRDSRRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKNSGGfSKDEIFDA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   143 VMVCTGHFLNPHLPleAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTgtwvlg 222
Cdd:PLN02172 165 VVVCNGHYTEPNVA--HIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASRA------ 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   223 RSSDwgypynmmvtrrccSFIAQVLPSRFLnWIQERklnKRFNHEDyglsitkgkkakfivndelpncilcGAItmktsv 302
Cdd:PLN02172 237 SESD--------------TYEKLPVPQNNL-WMHSE---IDTAHED-------------------------GSI------ 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   303 ieftetsaVFEDGTVEEnIDVVIFTTGYTFSFPFFE------------EPlkslctkkifLYKQVFPLNLErATLAIIGL 370
Cdd:PLN02172 268 --------VFKNGKVVY-ADTIVHCTGYKYHFPFLEtngymridenrvEP----------LYKHVFPPALA-PGLSFIGL 327

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 4503759   371 IGLkGSILSGTELQARWVTRVFKGLCKIpPSQKLMME 407
Cdd:PLN02172 328 PAM-GIQFVMFEIQSKWVAAVLSGRVTL-PSEDKMME 362
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-531 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 1003.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759      2 AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNF 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     82 MNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFP 161
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    162 GIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCS 241
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    242 FIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAK-FIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEEN 320
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKePVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    321 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPP 400
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    401 SQKLMMEATEK-EQLIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKW 479
Cdd:pfam00743 401 QSEMMAEINKRqEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 4503759    480 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMShYLKAWGAPVLLASLLLIC 531
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSF-TLKIFGLPVVLVAIFLIL 531
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-395 7.17e-80

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 256.71  E-value: 7.17e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    5 VAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFtesskdgmtRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNH 84
Cdd:COG2072   9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRD---------NRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   85 EKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRpdfSETGQWDVVTETeGKQNRAvfDAVMVCTGHFLNPHLPleAFPGIH 164
Cdd:COG2072  80 DEILAYLEAYADKFGLRRPIRFGTEVTSARWD---EADGRWTVTTDD-GETLTA--RFVVVATGPLSRPKIP--DIPGLE 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  165 KFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGR---SSDWGYPYNMMVTRrccs 241
Cdd:COG2072 152 DFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnyDPERGRPANYLGLE---- 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  242 FIAQVLPSRFLNWIqERKLNKRFNHEDYGL---SITKGKKaKFIVNDELPNCILCGAITMKTSVIE-FTETSAVFEDGTV 317
Cdd:COG2072 228 APPALNRRDARAWL-RRLLRAQVKDPELGLltpDYPPGCK-RPLLSTDYYEALRRGNVELVTGGIErITEDGVVFADGTE 305

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  318 EEnIDVVIFTTGYTFSFPFFEEPlkslctkKIF---------LYKQVFPLNLERatLAIIGLIGLKG--SILSGTELQAR 386
Cdd:COG2072 306 HE-VDVIVWATGFRADLPWLAPL-------DVRgrdgrsgprAYLGVVVPGFPN--LFFLGPNSPSGhsSLTLGAERQAR 375


                ....*....
gi 4503759  387 WVTRVFKGL 395
Cdd:COG2072 376 YIARLIAHM 384
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 2-407 6.58e-41

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 153.86  E-value: 6.58e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     2 AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFT-ESSKDGM----------TRVYKSLVTNVCKEMSCYS 70
Cdd:PLN02172  10 SQHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTpKSESDPLsldptrsivhSSVYESLRTNLPRECMGYR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    71 DFPF-------HEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITkrpdfSETGQWDVVTETEGK-QNRAVFDA 142
Cdd:PLN02172  90 DFPFvprfddeSRDSRRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKNSGGfSKDEIFDA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   143 VMVCTGHFLNPHLPleAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTgtwvlg 222
Cdd:PLN02172 165 VVVCNGHYTEPNVA--HIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASRA------ 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   223 RSSDwgypynmmvtrrccSFIAQVLPSRFLnWIQERklnKRFNHEDyglsitkgkkakfivndelpncilcGAItmktsv 302
Cdd:PLN02172 237 SESD--------------TYEKLPVPQNNL-WMHSE---IDTAHED-------------------------GSI------ 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   303 ieftetsaVFEDGTVEEnIDVVIFTTGYTFSFPFFE------------EPlkslctkkifLYKQVFPLNLErATLAIIGL 370
Cdd:PLN02172 268 --------VFKNGKVVY-ADTIVHCTGYKYHFPFLEtngymridenrvEP----------LYKHVFPPALA-PGLSFIGL 327

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 4503759   371 IGLkGSILSGTELQARWVTRVFKGLCKIpPSQKLMME 407
Cdd:PLN02172 328 PAM-GIQFVMFEIQSKWVAAVLSGRVTL-PSEDKMME 362
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
89-352 1.90e-17

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 83.04  E-value: 1.90e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     89 DYLQEFAEHFDLLkyIQFKTTVCSITKrpdfsETGQWDVVTetegkqNRAVFDA--VMVCTGHFLNPHLPleAFPGIHKf 166
Cdd:pfam13738  79 EYLRRVADHFELP--INLFEEVTSVKK-----EDDGFVVTT------SKGTYQAryVIIATGEFDFPNKL--GVPELPK- 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    167 kgqilHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWvLGRSSDwgypynmmvtrrccsfiaqv 246
Cdd:pfam13738 143 -----HYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEW-EDRDSD-------------------- 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    247 lPSRFLN-WIQERklnkrfnhedyglsitkgkkakfivndeLPNCILCGAITM--KTSVIEFTETSAV----FEDGTVEE 319
Cdd:pfam13738 197 -PSYSLSpDTLNR----------------------------LEELVKNGKIKAhfNAEVKEITEVDVSykvhTEDGRKVT 247

                         250       260       270
                  ....*....|....*....|....*....|...
gi 4503759    320 NIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLY 352
Cdd:pfam13738 248 SNDDPILATGYHPDLSFLKKGLFELDEDGRPVL 280
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 81-215 1.16e-08

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 56.82  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     81 FMNHEKFW-------DYLQEFAEHFDllKYIQFKTTVCSITKRPDfSETGQWDVVTETEGKQNRAVF-DAVMVCTGhfLN 152
Cdd:pfam13434  84 FYNLETFFpsrrefnDYLQWAASHLP--NRLRFGQEVESVEPDAE-RGEPLLRVRVRDADGEETTFLaRNLVLGTG--GE 158

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4503759    153 PHLPlEAFPGihkfKGQILHSQEY--KIPEGFQGKRVLVIGLGNTGGDIAVELSRT--AAQVLLSTR 215
Cdd:pfam13434 159 PYIP-ECARG----GERVFHSSEYleRIDRLAAKKRIAVVGSGQSAAEIFRDLLRRgpAYELTWVTR 220
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
4-215 2.56e-07

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 52.43  E-value: 2.56e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    4 KVAVIGAGVSGLSSIKCCVDEDLEPTCFERsDDIGG-LWKFTESskdgmtrvykslvtnvckemscysdfpfhEDYPNFM 82
Cdd:COG0492   2 DVVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGGqLATTKEI-----------------------------ENYPGFP 51

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   83 NHEKFWDYLQEF---AEHFDllkyIQFKTT-VCSITKrpdfsETGQWDVVTEtEGKQNRAvfDAVMVCTGHFLNPhLPLe 158
Cdd:COG0492  52 EGISGPELAERLreqAERFG----AEILLEeVTSVDK-----DDGPFRVTTD-DGTEYEA--KAVIIATGAGPRK-LGL- 117

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759  159 afPGIHKFKGQILHsqeYKIP-EGFQ--GKRVLVIGLGNTGGDIAVELSRTAAQVLLSTR 215
Cdd:COG0492 118 --PGEEEFEGRGVS---YCATcDGFFfrGKDVVVVGGGDSALEEALYLTKFASKVTLIHR 172
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 3-207 9.57e-06

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 48.24  E-value: 9.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759     3 KKVAVIGAGVSGLSsikcCVDEdL-----EPTCFERSDDIGGLWKFtesskdGMtrvykslvtnvckemscysdfpfhed 77
Cdd:PRK12810 144 KKVAVVGSGPAGLA----AADQ-LaraghKVTVFERADRIGGLLRY------GI-------------------------- 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    78 yPNF-MnhEKfwdylqEFAEH-FDLLKY--IQFKTTVcsitkrpdfsETGQwDVVTEtegkQNRAVFDAVMVCTGHFLNP 153
Cdd:PRK12810 187 -PDFkL--EK------EVIDRrIELMEAegIEFRTNV----------EVGK-DITAE----ELLAEYDAVFLGTGAYKPR 242

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4503759   154 HLPL--EAFPGIHK---FKGQILHSQEYKIPEGF---QGKRVLVIGlgntGGDIAVELSRTA 207
Cdd:PRK12810 243 DLGIpgRDLDGVHFamdFLIQNTRRVLGDETEPFisaKGKHVVVIG----GGDTGMDCVGTA 300
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 3-207 1.45e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 44.36  E-value: 1.45e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759    3 KKVAVIGAGVSGLSsikcCVDeDL-----EPTCFERSDDIGGLwkftesskdgMTrvykslvtnvckemscysdfpfhed 77
Cdd:COG0493 122 KKVAVVGSGPAGLA----AAY-QLaraghEVTVFEALDKPGGL----------LR------------------------- 161

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   78 Y--PNF-MnhEKfwDYLQefAEHfDLLK--YIQFKTTVcSITKrpDFSetgqwdvvteteGKQNRAVFDAVMVCTG---- 148
Cdd:COG0493 162 YgiPEFrL--PK--DVLD--REI-ELIEalGVEFRTNV-EVGK--DIT------------LDELLEEFDAVFLATGagkp 219

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 4503759  149 HFLNphLPLEAFPGIHK---F-KGQILHSQEYKIPegFQGKRVLVIGLGNTGGDIAvelsRTA 207
Cdd:COG0493 220 RDLG--IPGEDLKGVHSamdFlTAVNLGEAPDTIL--AVGKRVVVIGGGNTAMDCA----RTA 274
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-40 4.76e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 42.90  E-value: 4.76e-04
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 4503759    3 KKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGL 40
Cdd:COG1232   2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGL 39
PRK07233 PRK07233
hypothetical protein; Provisional
 4-40 8.69e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 41.80  E-value: 8.69e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 4503759     4 KVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGL 40
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGL 37
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-41 3.80e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 35.97  E-value: 3.80e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 4503759      7 VIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLW 41
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNA 35
PRK07208 PRK07208
hypothetical protein; Provisional
 1-40 4.45e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 39.87  E-value: 4.45e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 4503759     1 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGL 40
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGI 42
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 140-262 5.73e-03

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 39.20  E-value: 5.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4503759   140 FDAVMVCTGHFLN--PHLPLEAFPGI-------HKFKG-QILHSQEYKIPEgFQGKRVLVIGLGNTGGDIAVELSRT-AA 208
Cdd:PRK12770 119 YDAVLIATGTWKSrkLGIPGEDLPGVysaleylFRIRAaKLGYLPWEKVPP-VEGKKVVVVGAGLTAVDAALEAVLLgAE 197

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 4503759   209 QVLLSTRtgtwvlgRSSDWGYPYNMMVTR---RCCSFIAQVLPSRFL--NWIQERKLNK 262
Cdd:PRK12770 198 KVYLAYR-------RTINEAPAGKYEIERliaRGVEFLELVTPVRIIgeGRVEGVELAK 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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