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Conserved domains on  [gi|1045961244|ref|NP_001316545|]
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SCAN domain-containing protein 3 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4371 super family cl46273
Domain of unknown function (DUF4371);
711-827 4.44e-04

Domain of unknown function (DUF4371);


The actual alignment was detected with superfamily member pfam14291:

Pssm-ID: 480613  Cd Length: 236  Bit Score: 43.37  E-value: 4.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045961244  711 KKVAQ-VPLSNDTIARRIQE-----LANDMEDQLIEQIKlAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSA 784
Cdd:pfam14291  112 KKVLKnAPKNNTYTSPPIQNdivncFSNEVTRSIIEEMD-NDVFGILVDETADASDKEQMAIVFRYVDKYGVPIERFIGV 190

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1045961244  785 SLPTNTTSSELYEAVKNyIVNKCGLEFKFCVGVCSDGAASMTG 827
Cdd:pfam14291  191 IHVQETSSLSLKSAIDS-LLKSLGISLKKLRSQCYDGASNMSG 232
Dimer_Tnp_hAT super family cl05324
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1097-1144 7.26e-03

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


The actual alignment was detected with superfamily member pfam05699:

Pssm-ID: 399013  Cd Length: 83  Bit Score: 36.86  E-value: 7.26e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1045961244 1097 SFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1144
Cdd:pfam05699   21 EWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRL 68
 
Name Accession Description Interval E-value
DUF4371 pfam14291
Domain of unknown function (DUF4371);
711-827 4.44e-04

Domain of unknown function (DUF4371);


Pssm-ID: 405048  Cd Length: 236  Bit Score: 43.37  E-value: 4.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045961244  711 KKVAQ-VPLSNDTIARRIQE-----LANDMEDQLIEQIKlAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSA 784
Cdd:pfam14291  112 KKVLKnAPKNNTYTSPPIQNdivncFSNEVTRSIIEEMD-NDVFGILVDETADASDKEQMAIVFRYVDKYGVPIERFIGV 190

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1045961244  785 SLPTNTTSSELYEAVKNyIVNKCGLEFKFCVGVCSDGAASMTG 827
Cdd:pfam14291  191 IHVQETSSLSLKSAIDS-LLKSLGISLKKLRSQCYDGASNMSG 232
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1097-1144 7.26e-03

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 36.86  E-value: 7.26e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1045961244 1097 SFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1144
Cdd:pfam05699   21 EWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRL 68
 
Name Accession Description Interval E-value
DUF4371 pfam14291
Domain of unknown function (DUF4371);
711-827 4.44e-04

Domain of unknown function (DUF4371);


Pssm-ID: 405048  Cd Length: 236  Bit Score: 43.37  E-value: 4.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1045961244  711 KKVAQ-VPLSNDTIARRIQE-----LANDMEDQLIEQIKlAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSA 784
Cdd:pfam14291  112 KKVLKnAPKNNTYTSPPIQNdivncFSNEVTRSIIEEMD-NDVFGILVDETADASDKEQMAIVFRYVDKYGVPIERFIGV 190

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1045961244  785 SLPTNTTSSELYEAVKNyIVNKCGLEFKFCVGVCSDGAASMTG 827
Cdd:pfam14291  191 IHVQETSSLSLKSAIDS-LLKSLGISLKKLRSQCYDGASNMSG 232
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1097-1144 7.26e-03

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 36.86  E-value: 7.26e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1045961244 1097 SFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1144
Cdd:pfam05699   21 EWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRL 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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