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Conserved domains on  [gi|762205493|ref|NP_001292085|]
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serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PPP2R3C cd21505
serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma; Heterotrimeric ...
 3-327 0e+00

serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. This subfamily includes protein phosphatase subunit G5PR (also known as serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, G4-1, G5pr, GDRM, SPGF36, or C14orf10) that is encoded by the PPP2R3C gene. It is involved in the control of the dynamic organization of the cortical cytoskeleton and plays an important role in the organization of interphase microtubule arrays in part through the regulation of nucleation geometry. G5PR is involved in the ontogeny of multiple organs, especially critical for testis development and spermatogenesis. PPP2R3C gene variants cause syndromic 46,XY gonadal dysgenesis and impaired spermatogenesis in humans, and thus is emerging as a potential therapeutic target for male infertility.


:

Pssm-ID: 410338 [Multi-domain]  Cd Length: 382  Bit Score: 640.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493   3 GEEAMINYENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESD 82
Cdd:cd21505   58 GEEERINYEDFLKVREEAGPKCRPFFTPSVFLKLLRDDPYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVDGDGFLTESD 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  83 LENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSA 162
Cdd:cd21505  138 LENYILELIPTLPQLSGLEESFYSFYVCTAVRKFFFFLDPLRRGKIRIKDILASPFLDELLELRDEELSEELQESNWFSA 217

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 163 PSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKL 242
Cdd:cd21505  218 PSALRVYGQYLNLDKDHNGMLSKQELSRYGKGTLTSVFIDRVFQECLTYNGEMDYKTFLDFVLAMENRKEPQALQYFFRI 297

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 243 LDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWT 322
Cdd:cd21505  298 LDLKGQGYLTPFTLNYFFRAIQEKMKEHGQEPVSFEDVKDEIFDMVKPKDPLKITLQDLINSGQGDTVVSILIDLNGFWA 377


                 ....*
gi 762205493 323 YENRE 327
Cdd:cd21505  378 YENRE 382
 
Name Accession Description Interval E-value
PPP2R3C cd21505
serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma; Heterotrimeric ...
 3-327 0e+00

serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. This subfamily includes protein phosphatase subunit G5PR (also known as serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, G4-1, G5pr, GDRM, SPGF36, or C14orf10) that is encoded by the PPP2R3C gene. It is involved in the control of the dynamic organization of the cortical cytoskeleton and plays an important role in the organization of interphase microtubule arrays in part through the regulation of nucleation geometry. G5PR is involved in the ontogeny of multiple organs, especially critical for testis development and spermatogenesis. PPP2R3C gene variants cause syndromic 46,XY gonadal dysgenesis and impaired spermatogenesis in humans, and thus is emerging as a potential therapeutic target for male infertility.


Pssm-ID: 410338 [Multi-domain]  Cd Length: 382  Bit Score: 640.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493   3 GEEAMINYENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESD 82
Cdd:cd21505   58 GEEERINYEDFLKVREEAGPKCRPFFTPSVFLKLLRDDPYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVDGDGFLTESD 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  83 LENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSA 162
Cdd:cd21505  138 LENYILELIPTLPQLSGLEESFYSFYVCTAVRKFFFFLDPLRRGKIRIKDILASPFLDELLELRDEELSEELQESNWFSA 217

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 163 PSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKL 242
Cdd:cd21505  218 PSALRVYGQYLNLDKDHNGMLSKQELSRYGKGTLTSVFIDRVFQECLTYNGEMDYKTFLDFVLAMENRKEPQALQYFFRI 297

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 243 LDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWT 322
Cdd:cd21505  298 LDLKGQGYLTPFTLNYFFRAIQEKMKEHGQEPVSFEDVKDEIFDMVKPKDPLKITLQDLINSGQGDTVVSILIDLNGFWA 377


                 ....*
gi 762205493 323 YENRE 327
Cdd:cd21505  378 YENRE 382
EF-hand_13 pfam17958
EF-hand domain; This entry represents an EF-hand domain found in one of the regulatory B ...
 74-148 3.71e-04

EF-hand domain; This entry represents an EF-hand domain found in one of the regulatory B subunits of PP2A.


Pssm-ID: 465586 [Multi-domain]  Cd Length: 90  Bit Score: 38.88  E-value: 3.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 762205493   74 GQGYLRESDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDE 148
Cdd:pfam17958  14 GKNYLSREDFYPFVQDVVDTHPGLEFLREAeeFQDKYIQTVIARIFYVVNRSWSGKITLLELRKSDLLKAVRQLDEE 90
 
Name Accession Description Interval E-value
PPP2R3C cd21505
serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma; Heterotrimeric ...
 3-327 0e+00

serine/threonine protein phosphatase 2A regulatory subunit B" subunit gamma; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. This subfamily includes protein phosphatase subunit G5PR (also known as serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, G4-1, G5pr, GDRM, SPGF36, or C14orf10) that is encoded by the PPP2R3C gene. It is involved in the control of the dynamic organization of the cortical cytoskeleton and plays an important role in the organization of interphase microtubule arrays in part through the regulation of nucleation geometry. G5PR is involved in the ontogeny of multiple organs, especially critical for testis development and spermatogenesis. PPP2R3C gene variants cause syndromic 46,XY gonadal dysgenesis and impaired spermatogenesis in humans, and thus is emerging as a potential therapeutic target for male infertility.


Pssm-ID: 410338 [Multi-domain]  Cd Length: 382  Bit Score: 640.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493   3 GEEAMINYENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESD 82
Cdd:cd21505   58 GEEERINYEDFLKVREEAGPKCRPFFTPSVFLKLLRDDPYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVDGDGFLTESD 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  83 LENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSA 162
Cdd:cd21505  138 LENYILELIPTLPQLSGLEESFYSFYVCTAVRKFFFFLDPLRRGKIRIKDILASPFLDELLELRDEELSEELQESNWFSA 217

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 163 PSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKL 242
Cdd:cd21505  218 PSALRVYGQYLNLDKDHNGMLSKQELSRYGKGTLTSVFIDRVFQECLTYNGEMDYKTFLDFVLAMENRKEPQALQYFFRI 297

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 243 LDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWT 322
Cdd:cd21505  298 LDLKGQGYLTPFTLNYFFRAIQEKMKEHGQEPVSFEDVKDEIFDMVKPKDPLKITLQDLINSGQGDTVVSILIDLNGFWA 377


                 ....*
gi 762205493 323 YENRE 327
Cdd:cd21505  378 YENRE 382
PPP2R3 cd21339
serine/threonine protein phosphatase 2A regulatory subunit B"; Heterotrimeric serine/threonine ...
 61-323 9.81e-137

serine/threonine protein phosphatase 2A regulatory subunit B"; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. This family includes PP2A regulatory B'' subunits alpha, beta and gamma, encoded by PPP2R3A, PPP2R3B and PPP2R3C, respectively. It also includes subunit delta encoded by PPP2R3D in mouse. These B-family regulatory subunits play various roles including regulation of cytoskeletal assembly, neuronal differentiation, mitogen-activated protein kinase signaling, and apoptosis. Subunits alpha and beta contain two-domain elongated structure with two calcium EF-hands which mediate Ca2+-dependent changes in phosphatase activity.


Pssm-ID: 410336  Cd Length: 259  Bit Score: 388.86  E-value: 9.81e-137
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  61 HQTRIGLSLYDvAGQGYLRESDLENYILELIPTLPQLDGLEK--SFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSF 138
Cdd:cd21339    1 DATKFGLLLYD-PGCGYLRQEDFEPYLQDVVPTHPGLDFLKKapEFHSRYITTVIQRIFYFVNRSWSGKITIQEIRASSF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 139 LDDLLELRDEELSKesQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTY------D 212
Cdd:cd21339   80 LQDLALLEEEEDIN--QETNWFSYEHFYVIYCKFWELDTDHDLMISKEDLSRYNDAAMSNVFIDRIFSGAVTRgktiqkE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 213 GEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKD 292
Cdd:cd21339  158 GEMSYADFVWFLISEEDKKEPTSIEYWFRCLDIDGDGYLSVFELEYFYEEQCERMKIHGIEPLPFQDVLCQILDLVKPKD 237

                        250       260       270
                 ....*....|....*....|....*....|.
gi 762205493 293 PLKISLQDLINSNqgdtvttilIDLNGFWTY 323
Cdd:cd21339  238 PGKITLQDLKRCN---------IALNFFDTF 259
PPP2R3A cd21506
serine/threonine protein phosphatase 2A regulatory subunit B" subunit alpha; Heterotrimeric ...
 74-327 1.77e-33

serine/threonine protein phosphatase 2A regulatory subunit B" subunit alpha; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. This group contains protein phosphatase subunit PR130 (also known as protein phosphatase 2A regulatory subunit B'' subunit alpha, PR72, or PPP2R3) that is encoded by the PPP2R3A gene. PR130 and PR72 subunits are derived from the same gene through differential splicing; they harbor specific N-terminal domains of different lengths that are encoded by alternatively spliced exons and have identical C-termini. The common C-terminus contains a two-domain elongated structure with two calcium EF-hands which mediate Ca2+-dependent changes in phosphatase activity. The PR130 subunit has been shown to interact with the LIM domain of lipoma-preferred partner (LPP) through a conserved Zn2+-finger-like motif in the N-terminus of PR130.


Pssm-ID: 410339  Cd Length: 284  Bit Score: 125.05  E-value: 1.77e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  74 GQGYLRESDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEEls 151
Cdd:cd21506   23 NCSYLEQEDFIPLLQDIVDTHPGLTFLKDApeFHSRYITTVIQRIFYTVNRSWSGKITLTELRKSNFLQTLALLEEED-- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 152 KESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTY------DGEMDYKTYLDFVL 225
Cdd:cd21506  101 DINQITDYFSYEHFYVIYCKFWELDTDHDLYIDQKDLARYNDQASSSRIIERIFSGAVTRgnsvqkEGRMSYADFVWFLI 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 226 ALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSN 305
Cdd:cd21506  181 SEEDKRNPTSIEYWFRCMDLDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPEVDGKITLRDLKRCR 260

                        250       260
                 ....*....|....*....|..
gi 762205493 306 QGDTVTTILIDLNGFWTYENRE 327
Cdd:cd21506  261 MAHIFYDTFFNLEKYLDHEQRD 282
PPP2R3A_B-like cd21504
serine/threonine protein phosphatase 2A regulatory subunit B" alpha and beta subunits, and ...
 77-320 2.35e-33

serine/threonine protein phosphatase 2A regulatory subunit B" alpha and beta subunits, and similar proteins; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. These B-family regulatory subunits play various roles including regulation of cytoskeletal assembly, neuronal differentiation, mitogen-activated protein kinase signaling, and apoptosis. This subfamily includes protein phosphatase 2A regulatory subunit B'' subunits alpha and beta, encoded by PPP2R3A and PPP2R3B. It also includes subunit delta encoded by PPP2R3D in mouse. They contain two-domain elongated structures with two calcium EF-hands which mediate Ca2+-dependent changes in phosphatase activity.


Pssm-ID: 410337  Cd Length: 274  Bit Score: 124.20  E-value: 2.35e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  77 YLRESDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEElsKES 154
Cdd:cd21504   26 YLVPEDFKPFLQDLLDTHPGLEFLQDTpeFQERYAETVIYRIFYSVNRSWSGRITLRELRRSNLLQALLLLDEEE--DIN 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 155 QETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLT-----YDGEMDYKTYLDFVLALEN 229
Cdd:cd21504  104 KVLRYFSYEHFYVIYCKFWELDTDHDLLIDKDDLLRYGDHALSPRIVDRIFSGAVRrfksgKEGKMSYEDFVWFILSEED 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 230 RKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDT 309
Cdd:cd21504  184 KTSPTSIEYWFRCMDLDGDGVLSMYEMEYFYEEQLQRMECLGIEPVPFEDILCQMLDMIKPENEGKITLRDLKRCKLAGN 263

                        250
                 ....*....|.
gi 762205493 310 VTTILIDLNGF 320
Cdd:cd21504  264 FFNTLFNLNKF 274
PPP2R3B cd21507
serine/threonine protein phosphatase 2A regulatory subunit B" subunit beta; Heterotrimeric ...
 67-301 8.09e-29

serine/threonine protein phosphatase 2A regulatory subunit B" subunit beta; Heterotrimeric serine/threonine protein phosphatase 2A (PP2A) consists of scaffolding (A), catalytic (C), and variable (B, B', and B") subunits. The variable subunits dictate subcellular localization and substrate specificity of the PP2A holoenzyme. This group contains protein phosphatase subunit PR70 (also known as protein phosphatase 2 regulatory subunit B'' subunit beta, PR48, NYREN8, PPP2R3L, or PPP2R3LY) that is encoded by the PPP2R3B gene. This substrate-recognizing subunit of PP2A has a two-domain elongated structure with two calcium EF-hands, each displaying different affinities to Ca2+. PPP2R3B/PR70 is a gonosomal melanoma tumor suppressor gene; PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing the cell division cycle 6 (CDC6)-chromatin licensing and DNA replication factor 1 (CDT1) interaction, which delays the firing of origins of DNA replication.


Pssm-ID: 410340  Cd Length: 355  Bit Score: 114.28  E-value: 8.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493  67 LSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLE 144
Cdd:cd21507   90 VHLLMKPGCNYLVQEDFIPFLQDVVNTHPGLSFLKEAseFHSRYITTVIQRIFYTVNRSWSGRITCTELRRSSFLQNVAL 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 145 LRDEElsKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTY------DGEMDYK 218
Cdd:cd21507  170 LEEEA--DINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQKDLARHNDHAISNRMIERIFSGAVTRgrkaqkEGKISYA 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 762205493 219 TYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISL 298
Cdd:cd21507  248 DFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMYELEYFYEEQCQKLDNMAIEPLPFEDCLCQMLDLVKPRTEGKITL 327


                 ...
gi 762205493 299 QDL 301
Cdd:cd21507  328 HDL 330
EF-hand_13 pfam17958
EF-hand domain; This entry represents an EF-hand domain found in one of the regulatory B ...
 74-148 3.71e-04

EF-hand domain; This entry represents an EF-hand domain found in one of the regulatory B subunits of PP2A.


Pssm-ID: 465586 [Multi-domain]  Cd Length: 90  Bit Score: 38.88  E-value: 3.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 762205493   74 GQGYLRESDLENYILELIPTLPQLDGLEKS--FYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDE 148
Cdd:pfam17958  14 GKNYLSREDFYPFVQDVVDTHPGLEFLREAeeFQDKYIQTVIARIFYVVNRSWSGKITLLELRKSDLLKAVRQLDEE 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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