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Conserved domains on  [gi|666335617|ref|NP_001287964|]
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ETS domain-containing transcription factor ERF isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ets super family cl02599
Ets-domain;
1-36 5.49e-17

Ets-domain;


The actual alignment was detected with superfamily member smart00413:

Pssm-ID: 470627  Cd Length: 87  Bit Score: 75.77  E-value: 5.49e-17
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 666335617     1 MNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL 36
Cdd:smart00413  52 MNYEKLSRALRYYYKKNILEKVPGKRLVYKFVKNPL 87
PHA03247 super family cl33720
large tegument protein UL36; Provisional
51-308 3.32e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 3.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617   51 GAVPQSAPPVPSGgshfRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPR 130
Cdd:PHA03247 2693 GSLTSLADPPPPP----PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA 2768
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  131 ARPPGPPdlgafRGPPLARLPHdPGVFRVYPRPRGGPEPLSPFPV-SPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLS 209
Cdd:PHA03247 2769 PAPPAAP-----AAGPPRRLTR-PAVASLSESRESLPSPWDPADPpAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  210 PmypsggGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVynyhlSPRAFLHYPGLVVPQP---QRPDKCPLPPMAPETPPVP 286
Cdd:PHA03247 2843 P------GPPPPSLPLGGSVAPGGDVRRRPPSRSPAA-----KPAAPARPPVRRLARPavsRSTESFALPPDQPERPPQP 2911
                         250       260
                  ....*....|....*....|..
gi 666335617  287 SSASSSSSSSSSPFKFKLQPPP 308
Cdd:PHA03247 2912 QAPPPPQPQPQPPPPPQPQPPP 2933
 
Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
1-36 5.49e-17

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 75.77  E-value: 5.49e-17
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 666335617     1 MNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL 36
Cdd:smart00413  52 MNYEKLSRALRYYYKKNILEKVPGKRLVYKFVKNPL 87
Ets pfam00178
Ets-domain;
1-31 4.53e-16

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 72.91  E-value: 4.53e-16
                          10        20        30
                  ....*....|....*....|....*....|.
gi 666335617    1 MNYDKLSRALRYYYNKRILHKTKGKRFTYKF 31
Cdd:pfam00178  50 MTYEKLSRALRYYYKKGILEKVPGKRLTYRF 80
PHA03247 PHA03247
large tegument protein UL36; Provisional
51-308 3.32e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 3.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617   51 GAVPQSAPPVPSGgshfRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPR 130
Cdd:PHA03247 2693 GSLTSLADPPPPP----PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA 2768
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  131 ARPPGPPdlgafRGPPLARLPHdPGVFRVYPRPRGGPEPLSPFPV-SPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLS 209
Cdd:PHA03247 2769 PAPPAAP-----AAGPPRRLTR-PAVASLSESRESLPSPWDPADPpAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  210 PmypsggGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVynyhlSPRAFLHYPGLVVPQP---QRPDKCPLPPMAPETPPVP 286
Cdd:PHA03247 2843 P------GPPPPSLPLGGSVAPGGDVRRRPPSRSPAA-----KPAAPARPPVRRLARPavsRSTESFALPPDQPERPPQP 2911
                         250       260
                  ....*....|....*....|..
gi 666335617  287 SSASSSSSSSSSPFKFKLQPPP 308
Cdd:PHA03247 2912 QAPPPPQPQPQPPPPPQPQPPP 2933
 
Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
1-36 5.49e-17

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 75.77  E-value: 5.49e-17
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 666335617     1 MNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKL 36
Cdd:smart00413  52 MNYEKLSRALRYYYKKNILEKVPGKRLVYKFVKNPL 87
Ets pfam00178
Ets-domain;
1-31 4.53e-16

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 72.91  E-value: 4.53e-16
                          10        20        30
                  ....*....|....*....|....*....|.
gi 666335617    1 MNYDKLSRALRYYYNKRILHKTKGKRFTYKF 31
Cdd:pfam00178  50 MTYEKLSRALRYYYKKGILEKVPGKRLTYRF 80
PHA03247 PHA03247
large tegument protein UL36; Provisional
51-308 3.32e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 3.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617   51 GAVPQSAPPVPSGgshfRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPR 130
Cdd:PHA03247 2693 GSLTSLADPPPPP----PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPA 2768
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  131 ARPPGPPdlgafRGPPLARLPHdPGVFRVYPRPRGGPEPLSPFPV-SPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLS 209
Cdd:PHA03247 2769 PAPPAAP-----AAGPPRRLTR-PAVASLSESRESLPSPWDPADPpAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  210 PmypsggGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVynyhlSPRAFLHYPGLVVPQP---QRPDKCPLPPMAPETPPVP 286
Cdd:PHA03247 2843 P------GPPPPSLPLGGSVAPGGDVRRRPPSRSPAA-----KPAAPARPPVRRLARPavsRSTESFALPPDQPERPPQP 2911
                         250       260
                  ....*....|....*....|..
gi 666335617  287 SSASSSSSSSSSPFKFKLQPPP 308
Cdd:PHA03247 2912 QAPPPPQPQPQPPPPPQPQPPP 2933
PHA03247 PHA03247
large tegument protein UL36; Provisional
51-299 2.11e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617   51 GAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPA-----------------CSSSSSSLFSAVVARRLGRGSVSD 113
Cdd:PHA03247 2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPpspspaanepdphppptVPPPERPRDDPAPGRVSRPRRARR 2669
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  114 CSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPlarlphDPGvfrvyPRPRGGPEPLS---PFPVSPLAGPGSLLPPQLS 190
Cdd:PHA03247 2670 LGRAAQASSPPQRPRRRAARPTVGSLTSLADPP------PPP-----PTPEPAPHALVsatPLPPGPAAARQASPALPAA 2738
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 666335617  191 PALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQ--PQ 268
Cdd:PHA03247 2739 PAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPaaAL 2818
                         250       260       270
                  ....*....|....*....|....*....|.
gi 666335617  269 RPDKCPLPPMAPETPPVPSSASSSSSSSSSP 299
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPS 2849
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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