|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
7-536 |
0e+00 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 521.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 7 AERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRP--------- 77
Cdd:PRK09259 3 MSDQLQLTDGFHLVIDALKLNGIDTIYGVVGIPITDLARLAQAEGIRYIGFRHEQSAGNAAAAAGFLTQKPgvcltvsap 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 78 ------------------LLVIGGSSERN----QEtmGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGR 135
Cdd:PRK09259 83 gflngltalanattncfpMIMISGSSEREivdlQQ--GDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVSGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 136 PGACYVDIPADFVNLQVNVN-SIKYMERCMSP-PISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY 213
Cdd:PRK09259 161 PGGVYLDLPAKVLAQTMDADeALTSLVKVVDPaPAQLPAPEAVDRALDLLKKAKRPLIILGKGAAYAQADEQIREFVEKT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 214 KLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVT 293
Cdd:PRK09259 241 GIPFLPMSMAKGLLPDTHPQSAAAARSLALANADVVLLVGARLNWLLSHGKGKTWGADKKFIQIDIEPQEIDSNRPIAAP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 294 LLGNIHAVTKQLLEELDKTPWQYPPEskWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLP--RDCFVVSEG 371
Cdd:PRK09259 321 VVGDIGSVMQALLAGLKQNTFKAPAE--WLDALAERKEKNAAKMAEKLSTDTQPMNFYNALGAIRDVLKenPDIYLVNEG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 372 ANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAkdrspGQWIICVEGDSAFGFSGMEVETICRYNLPIILL 451
Cdd:PRK09259 399 ANTLDLARNIIDMYKPRHRLDCGTWGVMGIGMGYAIAAAVET-----GKPVVAIEGDSAFGFSGMEVETICRYNLPVTVV 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 452 VVNNNGIYQGFDTDTwkemlkfqDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLINIM 531
Cdd:PRK09259 474 IFNNGGIYRGDDVNL--------SGAGDPSPTVLVHHARYDKMMEAFGGVGYNVTTPDELRHALTEAIA-SGKPTLINVV 544
|
....*
gi 548923731 532 IEPQA 536
Cdd:PRK09259 545 IDPAA 549
|
|
| oxalate_oxc |
TIGR03254 |
oxalyl-CoA decarboxylase; In a number of bacteria, including Oxalobacter formigenes from the ... |
12-536 |
2.87e-166 |
|
oxalyl-CoA decarboxylase; In a number of bacteria, including Oxalobacter formigenes from the human gut, a two-gene operon of oxc (oxalyl-CoA decarboxylase) and frc (formyl-CoA transferase) encodes a system for degrading and therefore detoxifying oxalate. Members of this family are the thiamine pyrophosphate (TPP)-containing enzyme oxalyl-CoA decarboxylase. [Cellular processes, Detoxification]
Pssm-ID: 132298 [Multi-domain] Cd Length: 554 Bit Score: 483.56 E-value: 2.87e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRP-------------- 77
Cdd:TIGR03254 1 ALTDGFHLVIDALKLNGINTIYGVVGIPVTDLARLAQAKGMRYIGFRHEQSAGYAAAAAGFLTQKPgvcltvsapgflng 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 78 -------------LLVIGGSSERNQETM--GAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVD 142
Cdd:TIGR03254 81 ltalanattncfpMIMISGSSERHIVDLqqGDYEEMDQLAAAKPFAKAAYRVLRAEDIGIGIARAIRTAVSGRPGGVYLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 143 IPADFVNLQVNVN-SIKYMERCMSP-PISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPT 220
Cdd:TIGR03254 161 LPAAVLGQTMEAEkAKKTLVKVVDPaPKQLPSPDSVDRAVELLKDAKRPLILLGKGAAYAQADEEIREFVEKTGIPFLPM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 221 PMGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHA 300
Cdd:TIGR03254 241 SMAKGLLPDTHPQSAAAARSFALAEADVVMLVGARLNWLLSHGKGKLWGEDAKFIQVDIEPTEMDSNRPIAAPVVGDIGS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 301 VTKQLLEELdKTPWQYPPeSKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPR--DCFVVSEGANTMDIG 378
Cdd:TIGR03254 321 VVQALLSAA-KNGGVKPP-ADWRNAIKTKSEKNVAKMAERLSASESPMNYHGALEAIRDVLKDnpDIYLVNEGANTLDLA 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 379 RTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVvakdrSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGI 458
Cdd:TIGR03254 399 RNVIDMYKPRHRLDVGTWGVMGIGMGYAIAAAV-----ETGKPVVALEGDSAFGFSGMEVETICRYNLPVCVVIFNNGGI 473
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 548923731 459 YQGFDTDTwkemlkfqdATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLINIMIEPQA 536
Cdd:TIGR03254 474 YRGDDVNV---------VGADPAPTVLVHGARYDKMMKAFGGVGYNVTTPDELKAALNEALA-SGKPTLINAVIDPSA 541
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
12-536 |
1.35e-127 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 384.13 E-value: 1.35e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEI--AIAAQQlGIKYIGMRNEQAACYAASAIGYLT--------------- 74
Cdd:COG0028 1 MKMTGADALVEALEAEGVETVFGVPGGAILPLydALRRQS-GIRHILVRHEQGAAFMADGYARATgkpgvclvtsgpgat 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 75 ------------SRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVD 142
Cdd:COG0028 80 nlvtgladaymdSVPVLAITGQVPTSLIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPVVLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 143 IPADFVNLQVNVNSIKYMERCMSPPISmAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:COG0028 160 IPKDVQAAEAEEEPAPPELRGYRPRPA-PDPEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAPVVTTLM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYCVG-------AARSRALQFADVIVLFGARLNWILHFGLPPrYQPDVKFIQVDICAEELGNNVKPAVTLL 295
Cdd:COG0028 239 GKGAFPEDHPLYLGmlgmhgtPAANEALAEADLVLAVGARFDDRVTGNWDE-FAPDAKIIHIDIDPAEIGKNYPVDLPIV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 296 GNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSNEAASKElaskkslPMNYYTVFYHVQEQLPRDCFVVSEGANTM 375
Cdd:COG0028 318 GDAKAVLAALLEALEPRADDRAAWLARIAAWRAEYLAAYAADDG-------PIKPQRVIAALREALPDDAIVVTDVGQHQ 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 376 DIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 455
Cdd:COG0028 391 MWAARYLRFRRPRRFLTSGGLGTMGYGLPAAIGAKLARPDRP----VVAITGDGGFQMNLQELATAVRYGLPVKVVVLNN 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 456 NgiyqGFDTDTWKEMLKFQDAtavvPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLINIMIEPQ 535
Cdd:COG0028 467 G----GLGMVRQWQELFYGGR----YSGTDLPNPDFAKLAEAFGAKGERVETPEELEAALEEALA-SDGPALIDVRVDPE 537
|
.
gi 548923731 536 A 536
Cdd:COG0028 538 E 538
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
350-533 |
2.21e-90 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 274.79 E-value: 2.21e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 350 YYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAkdrsPGQWIICVEGDS 429
Cdd:cd02004 1 PYRVLHELQEALPDDAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALAR----PDKRVVLVEGDG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 430 AFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWkemlkfqDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPE 509
Cdd:cd02004 77 AFGFSGMELETAVRYNLPIVVVVGNNGGWYQGLDGQQL-------SYGLGLPVTTLLPDTRYDLVAEAFGGKGELVTTPE 149
|
170 180
....*....|....*....|....
gi 548923731 510 ELQKSLRQSLAdTTKPSLINIMIE 533
Cdd:cd02004 150 ELKPALKRALA-SGKPALINVIID 172
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
16-537 |
7.87e-74 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 244.63 E-value: 7.87e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 16 GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSR------------------- 76
Cdd:PRK05858 7 AGRLAARRLKAHGVDTMFTLSGGHLFPLYDGAREEGIRLIDVRHEQTAAFAAEAWAKLTRVpgvavltagpgvtngmsam 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 77 --------PLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFV 148
Cdd:PRK05858 87 aaaqfnqsPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFVDFPMDHA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 149 NLQVNVNSIKymERCMSPPISM-AETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 227
Cdd:PRK05858 167 FSMADDDGRP--GALTELPAGPtPDPDALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRGVV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 228 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLpprYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLE 307
Cdd:PRK05858 245 PADHPLAFSRARGKALGEADVVLVVGVPMDFRLGFGV---FGGTAQLVHVDDAPPQRAHHRPVAAGLYGDLSAILSALAG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 308 eldktPWQYPPE-SKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYL 386
Cdd:PRK05858 322 -----AGGDRTDhQGWIEELRTAETAARARDAAELADDRDPIHPMRVYGELAPLLDRDAIVIGDGGDFVSYAGRYIDPYR 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 387 PRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPIIlLVVNNNGIYqGFDTDT 466
Cdd:PRK05858 397 PGCWLDPGPFGCLGTGPGYALAARLARPSRQ----VVLLQGDGAFGFSLMDVDTLVRHNLPVV-SVIGNNGIW-GLEKHP 470
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 548923731 467 wKEMLKFQDATAVvppmcLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLaDTTKPSLINIMIEPQAT 537
Cdd:PRK05858 471 -MEALYGYDVAAD-----LRPGTRYDEVVRALGGHGELVTVPAELGPALERAF-ASGVPYLVNVLTDPSVA 534
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
10-530 |
5.21e-60 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 207.79 E-value: 5.21e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 10 SEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSR------------- 76
Cdd:PRK08617 1 TDKKKYGADLVVDSLINQGVKYVFGIPGAKIDRVFDALEDSGPELIVTRHEQNAAFMAAAIGRLTGKpgvvlvtsgpgvs 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 77 --------------PLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVD 142
Cdd:PRK08617 81 nlatglvtataegdPVVAIGGQVKRADRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 143 IPADFVNLQVNVNSIKYMErcmSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK08617 161 LPQDVVDAPVTSKAIAPLS---KPKLGPASPEDINYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVVETFQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYC----VGAARSRA----LQFADVIVLFG-------ARlNWILHfglppryqPDVKFIQVDICAEELGNN 287
Cdd:PRK08617 238 AAGVISRELEDHffgrVGLFRNQPgdelLKKADLVITIGydpieyePR-NWNSE--------GDATIIHIDVLPAEIDNY 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 288 VKPAVTLLGNIHAVTKQLLEELDktPWQYPPESKwwKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFV 367
Cdd:PRK08617 309 YQPERELIGDIAATLDLLAEKLD--GLSLSPQSL--EILEELRAQLEELAERPARLEEGAVHPLRIIRALQDIVTDDTTV 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 368 vseganTMDIG-------RTvLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAFGFSGMEVET 440
Cdd:PRK08617 385 ------TVDVGshyiwmaRY-FRSYEPRHLLFSNGMQTLGVALPWAIAAALV----RPGKKVVSVSGDGGFLFSAMELET 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 441 ICRYNLPIILLVVNNNgiyqGFDTDTWKEMLKFQDATAV-------VppmcllpnsHYEQvmtAFGGKGYFVQTPEELQK 513
Cdd:PRK08617 454 AVRLKLNIVHIIWNDG----HYNMVEFQEEMKYGRSSGVdfgpvdfV---------KYAE---SFGAKGLRVTSPDELEP 517
|
570
....*....|....*..
gi 548923731 514 SLRQSLaDTTKPSLINI 530
Cdd:PRK08617 518 VLREAL-ATDGPVVIDI 533
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
16-532 |
2.47e-54 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 192.35 E-value: 2.47e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 16 GAKVIAQALKTQDVEYIFGIVG---IPVTEiaiAAQQLGIKYIGMRNEQAACYAASAIGYLTSR---------------- 76
Cdd:PRK08322 3 AADLFVKCLENEGVEYIFGIPGeenLDLLE---ALRDSSIKLILTRHEQGAAFMAATYGRLTGKagvclstlgpgatnlv 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 77 -----------PLLVIGGSSERNQETMGAFQefpQVEACRLY---TKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVD 142
Cdd:PRK08322 80 tgvayaqlggmPMVAITGQKPIKRSKQGSFQ---IVDVVAMMaplTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 143 IPADFVNLQVnvnSIKYMERCMSPPiSMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK08322 157 LPEDIAAEET---DGKPLPRSYSRR-PYASPKAIERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFTTQM 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYCVGAAR-------SRALQFADVIVLFGARLnwiLHFglPP-RYQP--DVKFIQVDICAEELGNNVKPAV 292
Cdd:PRK08322 233 GKGVIPETHPLSLGTAGlsqgdyvHCAIEHADLIINVGHDV---IEK--PPfFMNPngDKKVIHINFLPAEVDPVYFPQV 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 293 TLLGNIHAVTKQLLEELDKTPWQYPPeskWWKTLREKMKSNEAaskELASKKSLPMNYYTVFYHVQEQLPRDCFVVSE-G 371
Cdd:PRK08322 308 EVVGDIANSLWQLKERLADQPHWDFP---RFLKIREAIEAHLE---EGADDDRFPMKPQRIVADLRKVMPDDDIVILDnG 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 372 ANTMDIGRtvlqNYLPRHR----LDAGtFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLP 447
Cdd:PRK08322 382 AYKIWFAR----NYRAYEPntclLDNA-LATMGAGLPSAIAAKLVHPDRK----VLAVCGDGGFMMNSQELETAVRLGLP 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 448 IILLVVNNNgiyqGFDTDTWKEMLKFQDATAVVppmclLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSL 527
Cdd:PRK08322 453 LVVLILNDN----AYGMIRWKQENMGFEDFGLD-----FGNPDFVKYAESYGAKGYRVESADDLLPTLEEALA-QPGVHV 522
|
....*
gi 548923731 528 INIMI 532
Cdd:PRK08322 523 IDCPV 527
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
16-534 |
5.37e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 178.79 E-value: 5.37e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 16 GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAAS--------------------------- 68
Cdd:PRK06276 3 GAEAIIKALEAEGVKIIFGYPGGALLPFYDALYDSDLIHILTRHEQAAAHAADgyarasgkvgvcvatsgpgatnlvtgi 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 AIGYLTSRPLLVIGGSSERNQETMGAFQEfpqVEACRLY---TKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPA 145
Cdd:PRK06276 83 ATAYADSSPVIALTGQVPTKLIGNDAFQE---IDALGIFmpiTKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDLPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 146 DFVNLQVNVNSIKYMERCMSP---PISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK06276 160 DVQEGELDLEKYPIPAKIDLPgykPTTFGHPLQIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVKIPVCTTLM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYCVG-------AARSRALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKFIQVDICAEELGNNVKP 290
Cdd:PRK06276 240 GKGAFPEDHPLALGmvgmhgtKAANYSVTESDVLIAIGCR------FsdrttGDISSFAPNAKIIHIDIDPAEIGKNVRV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 291 AVTLLGNIHAVTKQLLEELDKTpwQYPPESKWWKTLREKMKSneaaSKELASKKSLPMNYYTVFYHVQEQLpRDCFVVSE 370
Cdd:PRK06276 314 DVPIVGDAKNVLRDLLAELMKK--EIKNKSEWLERVKKLKKE----SIPRMDFDDKPIKPQRVIKELMEVL-REIDPSKN 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 371 GANTMDIGRT------VLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAkdrsPGQWIICVEGDSAFGFSGMEVETICRY 444
Cdd:PRK06276 387 TIITTDVGQNqmwmahFFKTSAPRSFISSGGLGTMGFGFPAAIGAKVAK----PDANVIAITGDGGFLMNSQELATIAEY 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 445 NLPIILLVVNNNG---IYQgfdtdtWKEMLKFQDATAV----VPPMCLLPNShyeqvmtaFGGKGYFVQTPEELQKSLRQ 517
Cdd:PRK06276 463 DIPVVICIFDNRTlgmVYQ------WQNLYYGKRQSEVhlgeTPDFVKLAES--------YGVKADRVEKPDEIKEALKE 528
|
570
....*....|....*..
gi 548923731 518 SLADtTKPSLINIMIEP 534
Cdd:PRK06276 529 AIKS-GEPYLLDIIIDP 544
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
2-536 |
1.35e-47 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 174.56 E-value: 1.35e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 2 PDSNFAERSEEQVsgAKVIAQALKTQDVEYIFGiVGIPvTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRP---- 77
Cdd:PRK06112 4 PLSAPGFTLNGTV--AHAIARALKRHGVEQIFG-QSLP-SALFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVavvt 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 78 --------LLVIGGSS---------------ERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYG 134
Cdd:PRK06112 80 aqngpaatLLVAPLAEalkasvpivalvqdvNRDQTDRNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 135 RPGACYVDIPADFVNlqvnvnsikymERCMSP-----------PI--SMAETSAVCTAASVIRNAKQPLLIIGKGAAYAH 201
Cdd:PRK06112 160 RPGPVVLLLPADLLT-----------AAAAAPaaprsnslghfPLdrTVPAPQRLAEAASLLAQAQRPVVVAGGGVHISG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 202 AEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVG------AARSRALQF------ADVIVLFGARLN------WILhfg 263
Cdd:PRK06112 229 ASAALAALQSLAGLPVATTNMGKGAVDETHPLSLGvvgslmGPRSPGRHLrdlvreADVVLLVGTRTNqngtdsWSL--- 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 264 lpprYQPDVKFIQVDICAEELGNNVKpAVTLLGNIHAVTKQLLEELDKT--PWQYPPESKWWKTLREKMKSNEAASKELA 341
Cdd:PRK06112 306 ----YPEQAQYIHIDVDGEEVGRNYE-ALRLVGDARLTLAALTDALRGRdlAARAGRRAALEPAIAAGREAHREDSAPVA 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 342 SKKSLPMNYYTVFYHVQEQLPRDCFVVSEGA-NTMDIgrtvlQNYLPRHRldAGT-FGT-MGV-GLGFAIAAAVVAKDRS 417
Cdd:PRK06112 381 LSDASPIRPERIMAELQAVLTGDTIVVADASySSIWV-----ANFLTARR--AGMrFLTpRGLaGLGWGVPMAIGAKVAR 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 418 PGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVnNNGIYqGFDTDTwkEMLKFQDATAVVppmcllpnsHYEQV--- 494
Cdd:PRK06112 454 PGAPVICLVGDGGFAHVWAELETARRMGVPVTIVVL-NNGIL-GFQKHA--ETVKFGTHTDAC---------HFAAVdha 520
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 548923731 495 --MTAFGGKGYFVQTPEELQKSLRQSLADTTkPSLINIMIEPQA 536
Cdd:PRK06112 521 aiARACGCDGVRVEDPAELAQALAAAMAAPG-PTLIEVITDPSA 563
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
13-536 |
3.86e-47 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 173.26 E-value: 3.86e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 13 QVSGAKVIAQALKTQDVEYIFGIVGIPVTEI--AIAAQQLGIKYIGMRNEQAACYAASAIGYLTSR-------------- 76
Cdd:PRK08611 3 KIKAGEALVKLLQDWGIDHVYGIPGDSIDAVvdALRKEQDKIKFIQVRHEEVAALAAAAYAKLTGKigvclsiggpgaih 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 77 -------------PLLVIGGSSERNQETMGAFQEfpqVEACRLYTK---FSARPSSIEAIPFVIEKAVRSSiYGRPGACY 140
Cdd:PRK08611 83 llnglydakmdhvPVLALAGQVTSDLLGTDFFQE---VNLEKMFEDvavYNHQIMSAENLPEIVNQAIRTA-YEKKGVAV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 141 VDIPADFVNLQVNvNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAyaHAEESIKKLVEQYKLPFLPT 220
Cdd:PRK08611 159 LTIPDDLPAQKIK-DTTNKTVDTFRPTVPSPKPKDIKKAAKLINKAKKPVILAGLGAK--HAKEELLAFAEKAKIPIIHT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 221 PMGKGVVPDNHPYCVG-------AARSRALQFADVIVLFGArlnwilhfGLPPR-YQPD-VKFIQVDICAEELGNNVKPA 291
Cdd:PRK08611 236 LPAKGIIPDDHPYSLGnlgkigtKPAYEAMQEADLLIMVGT--------NYPYVdYLPKkAKAIQIDTDPANIGKRYPVN 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 292 VTLLGNIHAVTKQLLEELDKTPWQYPPES------KWWKTLREKMksneaaskelaSKKSLPMNYYTVFYHVQEQLPRDC 365
Cdd:PRK08611 308 VGLVGDAKKALHQLTENIKHVEDRRFLEAcqenmaKWWKWMEEDE-----------NNASTPIKPERVMAAIQKIADDDA 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 366 fVVSegantMDIGR-TVlqnYLPRHrLDAGT---------FGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSG 435
Cdd:PRK08611 377 -VLS-----VDVGTvTV---WSARY-LNLGTnqkfiisswLGTMGCGLPGAIAAKIAFPDRQ----AIAICGDGGFSMVM 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 436 MEVETICRYNLPIILLVVNNNGIyqgfdtdtwkEMLKF-QDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKS 514
Cdd:PRK08611 443 QDFVTAVKYKLPIVVVVLNNQQL----------AFIKYeQQAAGELEYAIDLSDMDYAKFAEACGGKGYRVEKAEELDPA 512
|
570 580
....*....|....*....|..
gi 548923731 515 LRQSLAdTTKPSLINIMIEPQA 536
Cdd:PRK08611 513 FEEALA-QDKPVIIDVYVDPNA 533
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
10-536 |
9.45e-47 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 171.88 E-value: 9.45e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 10 SEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAAS--------------------- 68
Cdd:PRK06048 4 STEKMTGARAIIKCLEKEGVEVIFGYPGGAIIPVYDELYDSDLRHILVRHEQAAAHAADgyaratgkvgvcvatsgpgat 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 ------AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVD 142
Cdd:PRK06048 84 nlvtgiATAYMDSVPIVALTGQVPRSMIGNDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLID 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 143 IPADFVNLQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK06048 164 LPKDVTTAEIDFDYPDKVELRGYKPTYKGNPQQIKRAAELIMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTTLM 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYCVGAA-------RSRALQFADVIVLFGARLNWILHfGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLL 295
Cdd:PRK06048 244 GIGAIPTEHPLSLGMLgmhgtkyANYAIQESDLIIAVGARFDDRVT-GKLASFAPNAKIIHIDIDPAEISKNVKVDVPIV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 296 GNihavTKQLLEELDKTpwqypPESKWWKTLREKMKSneaaskelaSKKSLPMNYYT---------VFYHVQEQLPrDCF 366
Cdd:PRK06048 323 GD----AKQVLKSLIKY-----VQYCDRKEWLDKINQ---------WKKEYPLKYKEredvikpqyVIEQIYELCP-DAI 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 367 VVSE-GANTMDIGRTVLQNYlPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYN 445
Cdd:PRK06048 384 IVTEvGQHQMWAAQYFKYKY-PRTFITSGGLGTMGYGFPAAIGAKVGKPDKT----VIDIAGDGSFQMNSQELATAVQND 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 446 LPIILLVVNNNgiYQGFdTDTWKEMLKFQDATAVvppmCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLaDTTKP 525
Cdd:PRK06048 459 IPVIVAILNNG--YLGM-VRQWQELFYDKRYSHT----CIKGSVDFVKLAEAYGALGLRVEKPSEVRPAIEEAV-ASDRP 530
|
570
....*....|.
gi 548923731 526 SLINIMIEPQA 536
Cdd:PRK06048 531 VVIDFIVECEE 541
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
13-535 |
1.74e-46 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 171.42 E-value: 1.74e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 13 QVSGAKVIAQALKTQDVEYIFGIVG---IPVTEIAIAAQQLG-IKYIGMRNEQAA----------------CYAAS---- 68
Cdd:CHL00099 9 EKTGAFALIDSLVRHGVKHIFGYPGgaiLPIYDELYAWEKKGlIKHILVRHEQGAahaadgyarstgkvgvCFATSgpga 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -------AIGYLTSRPLLVIGGSSERNQETMGAFQE-------FPQVEACrlYTKFSARP-SSIEAIPFVIEKavrssiY 133
Cdd:CHL00099 89 tnlvtgiATAQMDSVPLLVITGQVGRAFIGTDAFQEvdifgitLPIVKHS--YVVRDARDiSRIVAEAFYIAK------H 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 134 GRPGACYVDIPADfVNLQ-------VNVNSIKYMERCmsPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESI 206
Cdd:CHL00099 161 GRPGPVLIDIPKD-VGLEkfdyyppEPGNTIIKILGC--RPIYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 207 KKLVEQYKLPFLPTPMGKGVVPDNHPYCVG-------AARSRALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKF 274
Cdd:CHL00099 238 TELAELYKIPVTTTLMGKGIFDEDHPLCLGmlgmhgtAYANFAVSECDLLIALGAR------FddrvtGKLDEFACNAQV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 275 IQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPES--KWwktlREKMKSNEAASKELASKKSLPMNYYT 352
Cdd:CHL00099 312 IHIDIDPAEIGKNRIPQVAIVGDVKKVLQELLELLKNSPNLLESEQtqAW----RERINRWRKEYPLLIPKPSTSLSPQE 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 353 VFYHVQEQLPRDCFvvseganTMDIGRTVL--QNYL---PRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEG 427
Cdd:CHL00099 388 VINEISQLAPDAYF-------TTDVGQHQMwaAQFLkckPRKWLSSAGLGTMGYGLPAAIGAQIA----HPNELVICISG 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 428 DSAFGFSGMEVETICRYNLPIILLVVNNNgiYQGFdTDTWKE-----------MLKFQdatavvppmcllPNshYEQVMT 496
Cdd:CHL00099 457 DASFQMNLQELGTIAQYNLPIKIIIINNK--WQGM-VRQWQQafygeryshsnMEEGA------------PD--FVKLAE 519
|
570 580 590
....*....|....*....|....*....|....*....
gi 548923731 497 AFGGKGYFVQTPEELQKSLRQSLaDTTKPSLINIMIEPQ 535
Cdd:CHL00099 520 AYGIKGLRIKSRKDLKSSLKEAL-DYDGPVLIDCQVIED 557
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
13-533 |
7.25e-46 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 169.51 E-value: 7.25e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 13 QVSGAKVIAQALKTQDVEYIFGIVGIPVT----EIAiaaQQLGIKYIGMRNEQAACYAAS-------------------- 68
Cdd:PRK08527 2 KLSGSQMVCEALKEEGVKVVFGYPGGAILniydEIY---KQNYFKHILTRHEQAAVHAADgyarasgkvgvaivtsgpgf 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -------AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYV 141
Cdd:PRK08527 79 tnavtglATAYMDSIPLVLISGQVPNSLIGTDAFQEIDAVGISRPCVKHNYLVKSIEELPRILKEAFYIARSGRPGPVHI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 142 DIPADfvnLQVNVNSIKYMERCMSP---PISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFL 218
Cdd:PRK08527 159 DIPKD---VTATLGEFEYPKEISLKtykPTYKGNSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 219 PTPMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKFIQVDICAEELGN 286
Cdd:PRK08527 236 ETLMARGVLRSDDPLLLGMlgmhgsyAANMAMSECDLLISLGAR------FddrvtGKLSEFAKHAKIIHVDIDPSSISK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 287 NVKPAVTLLGNIHAVTKQLLEEL-DKTPWQYPPeskWWKTLREKMKSNEAASKElaSKKSLPMNYytVFYHVQEQLPRDC 365
Cdd:PRK08527 310 IVNADYPIVGDLKNVLKEMLEELkEENPTTYKE---WREILKRYNELHPLSYED--SDEVLKPQW--VIERVGELLGDDA 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 366 FVvseganTMDIGRT---VLQNY---LPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVE 439
Cdd:PRK08527 383 II------STDVGQHqmwVAQFYpfnYPRQLATSGGLGTMGYGLPAALGAKLAVPDKV----VINFTGDGSILMNIQELM 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 440 TICRYNLPIILLVVNNN--GIYQGFDTDTWKEMLKFQDATavvppmcLLPNshYEQVMTAFGGKGYFVQTPEELQKSLRQ 517
Cdd:PRK08527 453 TAVEYKIPVINIILNNNflGMVRQWQTFFYEERYSETDLS-------TQPD--FVKLAESFGGIGFRVTTKEEFDKALKE 523
|
570
....*....|....*.
gi 548923731 518 SLaDTTKPSLINIMIE 533
Cdd:PRK08527 524 AL-ESDKVALIDVKID 538
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
12-549 |
1.87e-45 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 168.46 E-value: 1.87e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQL-GIKYIGMRNEQAACYAAS---------------------- 68
Cdd:PRK08979 2 EMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHEKsGIEHILVRHEQAAVHMADgyaratgkvgvvlvtsgpgatn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -----AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK08979 82 titgiATAYMDSIPMVVLSGQVPSNLIGNDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVIDL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PADFVNLQVnVNSIKYME----RCMSPPISmAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLP 219
Cdd:PRK08979 162 PKDCLNPAI-LHPYEYPEsikmRSYNPTTS-GHKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVVS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 220 TPMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILHFGLpPRYQPDVKFIQVDICAEELGNNVKPAV 292
Cdd:PRK08979 240 TLMGLGAFPGTHKNSLGMlgmhgryEANMAMHNADLIFGIGVRFDDRTTNNL-EKYCPNATILHIDIDPSSISKTVRVDI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 293 TLLGNIHAVTKQLLEELDKTPWQYPPES--KWWKTLrEKMKSNEAASKELASKKSLPMNYYTVFYHVQEQlprDCFVVSe 370
Cdd:PRK08979 319 PIVGSADKVLDSMLALLDESGETNDEAAiaSWWNEI-EVWRSRNCLAYDKSSERIKPQQVIETLYKLTNG---DAYVAS- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 371 gantmDIGRTVLQNYL------PRHRLDAGTFGTMGVGLgfaiAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRY 444
Cdd:PRK08979 394 -----DVGQHQMFAALyypfdkPRRWINSGGLGTMGFGL----PAAMGVKFAMPDETVVCVTGDGSIQMNIQELSTALQY 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 445 NLPIILLVVNN----------NGIYQGFDTDTWkemlkfqdatavvppMCLLPNshYEQVMTAFGGKGYFVQTPEELQKS 514
Cdd:PRK08979 465 DIPVKIINLNNrflgmvkqwqDMIYQGRHSHSY---------------MDSVPD--FAKIAEAYGHVGIRISDPDELESG 527
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 548923731 515 LRQSLADTTKPSLINIMIE------PQATR-KAQDFHWLTRS 549
Cdd:PRK08979 528 LEKALAMKDRLVFVDINVDetehvyPMQIRgGAMNEMWLSKT 569
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
12-528 |
2.57e-45 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 168.11 E-value: 2.57e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLG-IKYIGMRNEQAACYAAS---------------------- 68
Cdd:PRK07979 2 EMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGgIDHVLVRHEQAAVHMADglaratgevgvvlvtsgpgatn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -----AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK07979 82 aitgiATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PADFVNLQVNVNSI---KYMERCMSPPISmAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPT 220
Cdd:PRK07979 162 PKDILNPANKLPYVwpeSVSMRSYNPTTQ-GHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVVSS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 221 PMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILHFGLPpRYQPDVKFIQVDICAEELGNNVKPAVT 293
Cdd:PRK07979 241 LMGLGAFPATHRQSLGMlgmhgtyEANMTMHNADVIFAVGVRFDDRTTNNLA-KYCPNATVLHIDIDPTSISKTVTADIP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 294 LLGNIHAVTKQLLEELDKTPWQYPPES--KWWKTLrEKMKSNEAASKELASKKSLPMNYYTVFYHVQEQlprDCFVVSeg 371
Cdd:PRK07979 320 IVGDARQVLEQMLELLSQESAHQPLDEirDWWQQI-EQWRARQCLKYDTHSEKIKPQAVIETLWRLTKG---DAYVTS-- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 372 antmDIGRTVLQNYL------PRHRLDAGTFGTMGVGLgfaiAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYN 445
Cdd:PRK07979 394 ----DVGQHQMFAALyypfdkPRRWINSGGLGTMGFGL----PAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYE 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 446 LPIILLVVNNNgiYQGFdTDTWKEMLKFQDATAVVppMCLLPNshYEQVMTAFGGKGYFVQTPEELQKSLRQSLADTTKP 525
Cdd:PRK07979 466 LPVLVLNLNNR--YLGM-VKQWQDMIYSGRHSQSY--MQSLPD--FVRLAEAYGHVGIQISHPDELESKLSEALEQVRNN 538
|
...
gi 548923731 526 SLI 528
Cdd:PRK07979 539 RLV 541
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
179-305 |
2.72e-45 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 156.18 E-value: 2.72e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 179 AASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVG-------AARSRALQFADVIVL 251
Cdd:pfam00205 4 AAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGmlgmhgtPAANEALEEADLVLA 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 548923731 252 FGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQL 305
Cdd:pfam00205 84 VGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVDVPIVGDAKETLEAL 137
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
15-536 |
5.47e-45 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 167.32 E-value: 5.47e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 15 SGAKVIAQALKTQDVEYIFGIVGIPVTEIAIA----AQQLGIKYIGMRNEQAACYAASA--------------------- 69
Cdd:PRK06456 3 TGARILVDSLKREGVKVIFGIPGLSNMQIYDAfvedLANGELRHVLMRHEQAAAHAADGyarasgvpgvctatsgpgttn 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 70 ------IGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK06456 83 lvtgliTAYWDSSPVIAITGQVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVVIDI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PADFVNLQvnVNSIKYMERCMSPPI----SMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLP 219
Cdd:PRK06456 163 PRDIFYEK--MEEIKWPEKPLVKGYrdfpTRIDRLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIPIVS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 220 TPMGKGVVPDNHPYCVG-------AARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAV 292
Cdd:PRK06456 241 TFPGKTAIPHDHPLYFGpmgyygrAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDGEKAIKVDV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 293 TLLGNihavTKQLLEELDKTPWQYPPE---SKWWKTLREkmksneaaSKElaskkslpmnYYTVFYHVQEQ--------- 360
Cdd:PRK06456 321 GIYGN----AKIILRELIKAITELGQKrdrSAWLKRVKE--------YKE----------YYSQFYYTEENgklkpwkim 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 361 ------LPRDCfVVSEGANTMDIGRTVLQNYL-PRHRLDAGTFGTMGVGLgfaiAAAVVAKDRSPGQWIICVEGDSAFGF 433
Cdd:PRK06456 379 ktirqaLPRDA-IVTTGVGQHQMWAEVFWEVLePRTFLTSSGMGTMGFGL----PAAMGAKLARPDKVVVDLDGDGSFLM 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 434 SGMEVETICRYNLPIILLVvnnngiyqgFDTDTWKEMLKFQDA--TAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEEL 511
Cdd:PRK06456 454 TGTNLATAVDEHIPVISVI---------FDNRTLGLVRQVQDLffGKRIVGVDYGPSPDFVKLAEAFGALGFNVTTYEDI 524
|
570 580
....*....|....*....|....*
gi 548923731 512 QKSLRQSLADTTkPSLINIMIEPQA 536
Cdd:PRK06456 525 EKSLKSAIKEDI-PAVIRVPVDKEE 548
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
12-533 |
3.99e-44 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 164.41 E-value: 3.99e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEI--AIAAQQLGIKYIGMRNEQAACY------------------------ 65
Cdd:PRK08266 2 TTMTGGEAIVAGLVAHGVDTVFGLPGAQLYWLfdALYKAGDRIRVIHTRHEQAAGYmafgyarstgrpgvcsvvpgpgvl 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 66 ---AASAIGYLTSRPLLVIGGS--SERNQETMGAFQEFP-QVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGAC 139
Cdd:PRK08266 82 nagAALLTAYGCNSPVLCLTGQipSALIGKGRGHLHEMPdQLATLRSFTKWAERIEHPSEAPALVAEAFQQMLSGRPRPV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 140 YVDIPADFVNLQVNVNSIKYMERCMSPPIsmaETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEesIKKLVEQYKLPFLP 219
Cdd:PRK08266 162 ALEMPWDVFGQRAPVAAAPPLRPAPPPAP---DPDAIAAAAALIAAAKNPMIFVGGGAAGAGEE--IRELAEMLQAPVVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 220 TPMGKGVVPDNHP-YCVGAARSRALQFADVIVLFGARLnwILHFGLPPrYQPD-VKFIQVDICAEELGNnVKPAVTLLGN 297
Cdd:PRK08266 237 FRSGRGIVSDRHPlGLNFAAAYELWPQTDVVIGIGSRL--ELPTFRWP-WRPDgLKVIRIDIDPTEMRR-LKPDVAIVAD 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 298 IHAVTKQLLEELDKTPWQYPPEskwwktlREKMKSNEAASKELASKKSLPMNYYTVfyhVQEQLPRDCFVVSEGANTMDI 377
Cdd:PRK08266 313 AKAGTAALLDALSKAGSKRPSR-------RAELRELKAAARQRIQAVQPQASYLRA---IREALPDDGIFVDELSQVGFA 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 378 GRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNG 457
Cdd:PRK08266 383 SWFAFPVYAPRTFVTCGYQGTLGYGFPTALGAKVANPDRP----VVSITGDGGFMFGVQELATAVQHNIGVVTVVFNNNA 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 458 ----------IYQG--FDTDtwkemlkfqdatavvppmclLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKP 525
Cdd:PRK08266 459 ygnvrrdqkrRFGGrvVASD--------------------LVNPDFVKLAESFGVAAFRVDSPEELRAALEAALA-HGGP 517
|
....*...
gi 548923731 526 SLINIMIE 533
Cdd:PRK08266 518 VLIEVPVP 525
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
12-530 |
5.14e-44 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 165.22 E-value: 5.14e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVG---IPV-TEIAIAAQQLGIKYIGMRNEQAACYAAS------------------- 68
Cdd:PRK07418 17 QRATGAYALMDSLKRHGVKHIFGYPGgaiLPIyDELYKAEAEGWLKHILVRHEQGAAHAADgyaratgkvgvcfgtsgpg 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 --------AIGYLTSRPLLVIGGSSERNQETMGAFQE-------FPQVeacrlytKFS------ARPSSIEAIPFVIEka 127
Cdd:PRK07418 97 atnlvtgiATAQMDSVPMVVITGQVPRPAIGTDAFQEtdifgitLPIV-------KHSyvvrdpSDMARIVAEAFHIA-- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 128 vrSSiyGRPGACYVDIPADfVNLQ------VNVNSIKYmeRCMSPPISmAETSAVCTAASVIRNAKQPLLIIGKGAAYAH 201
Cdd:PRK07418 168 --SS--GRPGPVLIDIPKD-VGQEefdyvpVEPGSVKP--PGYRPTVK-GNPRQINAALKLIEEAERPLLYVGGGAISAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 202 AEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVG-------AARSRALQFADVIVLFGARlnwilhF-----GLPPRYQ 269
Cdd:PRK07418 240 AHAELKELAERFQIPVTTTLMGKGAFDEHHPLSVGmlgmhgtAYANFAVTECDLLIAVGAR------FddrvtGKLDEFA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 270 PDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQyPPESKW------WKT---LREKMKSNEAASKEl 340
Cdd:PRK07418 314 SRAKVIHIDIDPAEVGKNRRPDVPIVGDVRKVLVKLLERSLEPTTP-PRTQAWlerinrWKQdypLVVPPYEGEIYPQE- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 341 askkslpmnyytVFYHVQEQLPrDCFVvseganTMDIGRTVL--QNYL---PRHRLDAGTFGTMGVGLGFAIAAAVVAKD 415
Cdd:PRK07418 392 ------------VLLAVRDLAP-DAYY------TTDVGQHQMwaAQFLrngPRRWISSAGLGTMGFGMPAAMGVKVALPD 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 416 RSpgqwIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNgiYQGFdTDTWKEmlKFQD----ATAVVPPMcllPNshY 491
Cdd:PRK07418 453 EE----VICIAGDASFLMNIQELGTLAQYGINVKTVIINNG--WQGM-VRQWQE--SFYGerysASNMEPGM---PD--F 518
|
570 580 590
....*....|....*....|....*....|....*....
gi 548923731 492 EQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLINI 530
Cdd:PRK07418 519 VKLAEAFGVKGMVISERDQLKDAIAEALA-HDGPVLIDV 556
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
15-531 |
9.76e-44 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 163.44 E-value: 9.76e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 15 SGAKVIAQALKTQDVEYIFGIvgiPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLT-------------------- 74
Cdd:PRK06154 21 KVAEAVAEILKEEGVELLFGF---PVNELFDAAAAAGIRPVIARTERVAVHMADGYARATsgervgvfavqygpgaenaf 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 75 ---------SRPLLVIGGSSERNQETMGAfqEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPA 145
Cdd:PRK06154 98 ggvaqaygdSVPVLFLPTGYPRGSTDVAP--NFESLRNYRHITKWCEQVTLPDEVPELMRRAFTRLRNGRPGPVVLELPV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 146 DFVNLQVNVNSIKYmercmSPP---ISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK06154 176 DVLAEELDELPLDH-----RPSrrsRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEIPVMTTLN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYCVGAArSRA--------LQFADVIVLFGARLNWIlHFGLP-PRyqpDVKFIQVDICAEELGNNVKPAVT 293
Cdd:PRK06154 251 GKSAFPEDHPLALGSG-GRArpatvahfLREADVLFGIGCSLTRS-YYGLPmPE---GKTIIHSTLDDADLNKDYPIDHG 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 294 LLGNIHAVTKQLLEELDKTPWQYPPESKwwKTLREKMKSNEAASKELASK---KSLPMNYYTVFYHVQEQL-PRDCFVVS 369
Cdd:PRK06154 326 LVGDAALVLKQMIEELRRRVGPDRGRAQ--QVAAEIEAVRAAWLAKWMPKltsDSTPINPYRVVWELQHAVdIKTVIITH 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 370 EGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAFGFSGMEVETICRYNLPIi 449
Cdd:PRK06154 404 DAGSPRDQLSPFYVASRPGSYLGWGKTTQLGYGLGLAMGAKLA----RPDALVINLWGDAAFGMTGMDFETAVRERIPI- 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 450 LLVVNNNGIYQGFDTDTWKEMLKFQdATAVvppmcllpNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSL--ADTTKPSL 527
Cdd:PRK06154 479 LTILLNNFSMGGYDKVMPVSTTKYR-ATDI--------SGDYAAIARALGGYGERVEDPEMLVPALLRALrkVKEGTPAL 549
|
....
gi 548923731 528 INIM 531
Cdd:PRK06154 550 LEVI 553
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
29-532 |
1.46e-43 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 163.63 E-value: 1.46e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 29 VEYIFGIVG---IPVTEIAIAAqqlGIKYIGMRNEQAACYAASAIGYLTSRPLLVIGG---------------------- 83
Cdd:PRK07525 21 ITHAFGIIGsafMDASDLFPPA---GIRFIDVAHEQNAGHMADGYTRVTGRMGMVIGQngpgitnfvtavataywahtpv 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 84 ---SSERNQETMG--AFQEFPQVEACRLYTKFSAR---PSSI-EAIPFVIEKAVRSSiygrpGACYVDIPADFVNLQVNV 154
Cdd:PRK07525 98 vlvTPQAGTKTIGqgGFQEAEQMPMFEDMTKYQEEvrdPSRMaEVLNRVFDKAKRES-----GPAQINIPRDYFYGVIDV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 155 N--SIKYMERCMSPPISMAEtsavctAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHP 232
Cdd:PRK07525 173 EipQPVRLERGAGGEQSLAE------AAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGYLHNDAFPGSHP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 233 -------YCVGAARSRALQFADVIVLFGARLNwilHFGLPPRYQ----P-DVKFIQVDICAEELGNNVKPAVTLLGNIHA 300
Cdd:PRK07525 247 lwvgplgYNGSKAAMELIAKADVVLALGTRLN---PFGTLPQYGidywPkDAKIIQVDINPDRIGLTKKVSVGICGDAKA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 301 VTKQLLEEL-DKTPWQYPPE----------SKWWKTLREKMKSNEAAS----KELASKKSLPMNYYTVFYHVQEQLPRDC 365
Cdd:PRK07525 324 VARELLARLaERLAGDAGREerkaliaaekSAWEQELSSWDHEDDDPGtdwnEEARARKPDYMHPRQALREIQKALPEDA 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 366 FVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYN 445
Cdd:PRK07525 404 IVSTDIGNNCSIANSYLRFEKGRKYLAPGSFGNCGYAFPAIIGAKIACPDRP----VVGFAGDGAWGISMNEVMTAVRHN 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 446 LPIILLVVNNngiYQgfdtdtW----KEMLKFQDATAVVPPmcLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAD 521
Cdd:PRK07525 480 WPVTAVVFRN---YQ------WgaekKNQVDFYNNRFVGTE--LDNNVSYAGIAEAMGAEGVVVDTQEELGPALKRAIDA 548
|
570
....*....|...
gi 548923731 522 TT--KPSLINIMI 532
Cdd:PRK07525 549 QNegKTTVIEIMC 561
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
12-533 |
8.13e-43 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 161.24 E-value: 8.13e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLG-IKYIGMRNEQAAC-----YAAS----------------- 68
Cdd:PRK06882 2 KKLSGAEMVVQSLRDEGVEYVFGYPGGSVLDIYDAIHTLGgIEHVLVRHEQAAVhmadgYARStgkvgcvlvtsgpgatn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -----AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK06882 82 aitgiATAYTDSVPLVILSGQVPSNLIGTDAFQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVIDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PADFVNlQVNVNSIKYME----RCMSPPISmAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLP 219
Cdd:PRK06882 162 PKDMVN-PANKFTYEYPEevslRSYNPTVQ-GHKGQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 220 TPMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILHFGLpPRYQPDVKFIQVDICAEELGNNVKPAV 292
Cdd:PRK06882 240 SLMGLGAYPSTDKQFLGMlgmhgtyEANNAMHESDLILGIGVRFDDRTTNNL-AKYCPNAKVIHIDIDPTSISKNVPAYI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 293 TLLGNIHAVTKQ---LLEELDKTPWQYPPESkWWKTLREkMKSNEAASKELASKKSLPMNYYTVFYHVQEQlprDCFVVS 369
Cdd:PRK06882 319 PIVGSAKNVLEEflsLLEEENLAKSQTDLTA-WWQQINE-WKAKKCLEFDRTSDVIKPQQVVEAIYRLTNG---DAYVAS 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 370 egantmDIGRTVLQNYL------PRHRLDAGTFGTMGVGLgfaiAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICR 443
Cdd:PRK06882 394 ------DVGQHQMFAALhypfdkPRRWINSGGAGTMGFGL----PAAIGVKFAHPEATVVCVTGDGSIQMNIQELSTAKQ 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 444 YNLPIILLVVNNNgiYQGFdTDTWKEMLKFQDATAVVppMCLLPNshYEQVMTAFGGKGYFVQTPEELQKSLRQSLADTT 523
Cdd:PRK06882 464 YDIPVVIVSLNNR--FLGM-VKQWQDLIYSGRHSQVY--MNSLPD--FAKLAEAYGHVGIQIDTPDELEEKLTQAFSIKD 536
|
570
....*....|
gi 548923731 524 KPSLINIMIE 533
Cdd:PRK06882 537 KLVFVDVNVD 546
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
12-520 |
1.56e-41 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 157.44 E-value: 1.56e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAAS----------------------- 68
Cdd:PRK06725 13 EEVTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYESGLKHILTRHEQAAIHAAEgyarasgkvgvvfatsgpgatnl 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 ----AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIP 144
Cdd:PRK06725 93 vtglADAYMDSIPLVVITGQVATPLIGKDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGRPGPVLIDIP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 145 ADFVNLQVnvnSIKYMERCMSP---PISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 221
Cdd:PRK06725 173 KDVQNEKV---TSFYNEVVEIPgykPEPRPDSMKLREVAKAISKAKRPLLYIGGGVIHSGGSEELIEFARENRIPVVSTL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 222 MGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILHfGLPPRYQPDVKFIQVDICAEELGNNVKPAVTL 294
Cdd:PRK06725 250 MGLGAYPPGDPLFLGMlgmhgtyAANMAVTECDLLLALGVRFDDRVT-GKLELFSPHSKKVHIDIDPSEFHKNVAVEYPV 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 295 LGNIHAVTKQLLEELDKTPW-QYPPESKWWKtlREKMKSNEAASKELASKKSLPMnyytvfyhVQEQLPRDCFVVSEGAN 373
Cdd:PRK06725 329 VGDVKKALHMLLHMSIHTQTdEWLQKVKTWK--EEYPLSYKQKESELKPQHVINL--------VSELTNGEAIVTTEVGQ 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 374 TMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVvAKdrsPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVV 453
Cdd:PRK06725 399 HQMWAAHFYKAKNPRTFLTSGGLGTMGFGFPAAIGAQL-AK---EEELVICIAGDASFQMNIQELQTIAENNIPVKVFII 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 454 NNNgiYQGFdTDTWKEML---KFQDATAVVPpmcllpnsHYEQVMTAFGGKGYFVQTPEELQKSLRQSLA 520
Cdd:PRK06725 475 NNK--FLGM-VRQWQEMFyenRLSESKIGSP--------DFVKVAEAYGVKGLRATNSTEAKQVMLEAFA 533
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
17-530 |
6.62e-41 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 155.13 E-value: 6.62e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 17 AKVIAQALKTQDVEYIFGIVGIPVTEI--AIAAQqlGIKYIGMRNEQAA----------------CY---------AASA 69
Cdd:PRK07524 5 GEALVRLLEAYGVETVFGIPGVHTVELyrGLAGS--GIRHVTPRHEQGAgfmadgyarvsgkpgvCFiitgpgmtnIATA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 70 IG--YLTSRPLLVIGGSSERNQ--ETMGAFQEFP-QVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIP 144
Cdd:PRK07524 83 MGqaYADSIPMLVISSVNRRASlgKGRGKLHELPdQRAMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIEIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 145 ADFVNLQVNVNSIKYMERCMSPPismAETSAVCTAASVIRNAKQPLLIIGKGAAyaHAEESIKKLVEQYKLPFLPTPMGK 224
Cdd:PRK07524 163 LDVLAAPADHLLPAPPTRPARPG---PAPAALAQAAERLAAARRPLILAGGGAL--AAAAALRALAERLDAPVALTINAK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 225 GVVPDNHPYCVGAARS----RAL-QFADVIVLFGARLN-------WILHFGLPPRyqpdvkFIQVDICAEELGNNVKPAV 292
Cdd:PRK07524 238 GLLPAGHPLLLGASQSlpavRALiAEADVVLAVGTELGetdydvyFDGGFPLPGE------LIRIDIDPDQLARNYPPAL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 293 TLLGNIHAVTKQLLEELdktpwQYPPESKWWKTLREkmksnEAASKELASKKSLPMNYYTVFYH-VQEQLPRDCFV---- 367
Cdd:PRK07524 312 ALVGDARAALEALLARL-----PGQAAAADWGAARV-----AALRQALRAEWDPLTAAQVALLDtILAALPDAIFVgdst 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 368 --VSEGANTMDIGRtvlqnylPRHRLDAGT-FGTMGVGLGFAIAAAVVAKDRsPGqwiICVEGDSAFGFSGMEVETICRY 444
Cdd:PRK07524 382 qpVYAGNLYFDADA-------PRRWFNASTgYGTLGYGLPAAIGAALGAPER-PV---VCLVGDGGLQFTLPELASAVEA 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 445 NLPIILLVVNNNGiyqgfdtdtWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRqSLADTTK 524
Cdd:PRK07524 451 DLPLIVLLWNNDG---------YGEIRRYMVARDIEPVGVDPYTPDFIALARAFGCAAERVADLEQLQAALR-AAFARPG 520
|
....*.
gi 548923731 525 PSLINI 530
Cdd:PRK07524 521 PTLIEV 526
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
12-534 |
2.32e-40 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 154.13 E-value: 2.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAA-QQLGIKYIGMRNEQAACYAAS---------------------- 68
Cdd:PRK06466 2 ELLSGAEMLVRALRDEGVEYIYGYPGGAVLHIYDALfKQDKVEHILVRHEQAATHMADgyaratgktgvvlvtsgpgatn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -----AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK06466 82 aitgiATAYMDSIPMVVLSGQVPSTLIGEDAFQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRPGPVVVDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PADFVNLQVNVNSI---KYMERCMSPPiSMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPT 220
Cdd:PRK06466 162 PKDMTNPAEKFEYEypkKVKLRSYSPA-VRGHSGQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHLLNLPVTNT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 221 PMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILHFGlPPRYQPDVKFIQVDICAEELGNNVKPAVT 293
Cdd:PRK06466 241 LMGLGGFPGTDRQFLGMlgmhgtyEANMAMHHADVILAVGARFDDRVTNG-PAKFCPNAKIIHIDIDPASISKTIKADIP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 294 LLGNIHAVTKQLLE---ELDKTPWQyPPESKWWKTLREKMKSNEAASKELASKKSL-PMNYYTVFYHVQEQlprDCFVVS 369
Cdd:PRK06466 320 IVGPVESVLTEMLAilkEIGEKPDK-EALAAWWKQIDEWRGRHGLFPYDKGDGGIIkPQQVVETLYEVTNG---DAYVTS 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 370 egantmDIGRTVL---QNYL---PRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICR 443
Cdd:PRK06466 396 ------DVGQHQMfaaQYYKfnkPNRWINSGGLGTMGFGLPAAMGVKLAFPDQD----VACVTGEGSIQMNIQELSTCLQ 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 444 YNLPIILLVVNNNGIyqGFdTDTWKEMLkfQDATAVVPPMCLLPNshYEQVMTAFGGKGYFVQTPEELQKSLRQSLADTT 523
Cdd:PRK06466 466 YGLPVKIINLNNGAL--GM-VRQWQDMQ--YEGRHSHSYMESLPD--FVKLAEAYGHVGIRITDLKDLKPKLEEAFAMKD 538
|
570
....*....|.
gi 548923731 524 KPSLINIMIEP 534
Cdd:PRK06466 539 RLVFIDIYVDR 549
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
12-456 |
2.43e-39 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 151.01 E-value: 2.43e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIA-AQQLGIKYIGMRNEQAA----------------CYAASAIG--- 71
Cdd:PRK08155 11 KRFTGAELIVRLLERQGIRIVTGIPGGAILPLYDAlSQSTQIRHILARHEQGAgfiaqgmarttgkpavCMACSGPGatn 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 72 --------YLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK08155 91 lvtaiadaRLDSIPLVCITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWIDI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PADFVNLQVNVNSIKYMERCMSPPisMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMG 223
Cdd:PRK08155 171 PKDVQTAVIELEALPAPAEKDAAP--AFDEESIRDAAAMINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTLMA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 224 KGVVPDNHPYCVG-----AARSR--ALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKFIQVDICAEELGNNVKPA 291
Cdd:PRK08155 249 LGMLPKAHPLSLGmlgmhGARSTnyILQEADLLIVLGAR------FddraiGKTEQFCPNAKIIHVDIDRAELGKIKQPH 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 292 VTLLGNIHAVTKQLLeeldktPWQYPPESKWWKTLREKMKSNEAASKELASKkslPMNYYTVFYHVQEQLPRDCFVvseg 371
Cdd:PRK08155 323 VAIQADVDDVLAQLL------PLVEAQPRAEWHQLVADLQREFPCPIPKADD---PLSHYGLINAVAACVDDNAII---- 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 372 anTMDIGRT---VLQNY---LPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYN 445
Cdd:PRK08155 390 --TTDVGQHqmwTAQAYplnRPRQWLTSGGLGTMGFGLPAAIGAALANPERK----VLCFSGDGSLMMNIQEMATAAENQ 463
|
490
....*....|.
gi 548923731 446 LPIILLVVNNN 456
Cdd:PRK08155 464 LDVKIILMNNE 474
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
11-532 |
2.64e-39 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 151.13 E-value: 2.64e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 11 EEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEI--AIAAQQlGIKYIGMRNEQAAC-----YAAS--------------- 68
Cdd:PRK07282 7 ESPKSGSDLVLETLRDLGVDTIFGYPGGAVLPLydAIYNFE-GIRHILARHEQGALheaegYAKStgklgvavvtsgpga 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -------AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYV 141
Cdd:PRK07282 86 tnaitgiADAMSDSVPLLVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVVI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 142 DIPADFVNLQVN-VNSIKYMERCMSPPISmAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPT 220
Cdd:PRK07282 166 DLPKDVSALETDfIYDPEVNLPSYQPTLE-PNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 221 PMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILhFGLPPRYQPDVKFIQVDICAEELGNNVKPAVT 293
Cdd:PRK07282 245 LLGQGTIATSHPLFLGMggmhgsyAANIAMTEADFMINIGSRFDDRL-TGNPKTFAKNAKVAHIDIDPAEIGKIIKTDIP 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 294 LLGNIHAVTKQLLEElDKTPWQYppeSKWWKTL---REKMKSNEAASKELASKKSLPMnyytvfyhVQEQLPRDCFVVSe 370
Cdd:PRK07282 324 VVGDAKKALQMLLAE-PTVHNNT---EKWIEKVtkdKNRVRSYDKKERVVQPQAVIER--------IGELTNGDAIVVT- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 371 gantmDIGRTVL--QNYLP----RHRLDAGTFGTMgvglGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRY 444
Cdd:PRK07282 391 -----DVGQHQMwaAQYYPyqneRQLVTSGGLGTM----GFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELAILNIY 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 445 NLPIILLVVNNNGIyqGFdTDTWKEmlKFQDATAVVPPMCLLPNshYEQVMTAFGGKGYFVQTPEELQKSLRQSLADttK 524
Cdd:PRK07282 462 KVPIKVVMLNNHSL--GM-VRQWQE--SFYEGRTSESVFDTLPD--FQLMAQAYGIKHYKFDNPETLAQDLEVITED--V 532
|
....*...
gi 548923731 525 PSLINIMI 532
Cdd:PRK07282 533 PMLIEVDI 540
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
16-536 |
1.40e-38 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 148.87 E-value: 1.40e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 16 GAKVIAQALKTQDVEYIFGIVG---IPVTEiAIAAQQlGIKYIGMRNEQAACYAASAIGYLTSRP--------------- 77
Cdd:PRK08199 10 GGQILVDALRANGVERVFCVPGesyLAVLD-ALHDET-DIRVIVCRQEGGAAMMAEAYGKLTGRPgicfvtrgpgatnas 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 78 -------------LLVIG--GSSERNQEtmgAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVD 142
Cdd:PRK08199 88 igvhtafqdstpmILFVGqvARDFRERE---AFQEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGRPGPVVLA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 143 IPADFVNLQVNVNSIKYMERCMSPPiSMAETSAVctaASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK08199 165 LPEDVLSETAEVPDAPPYRRVAAAP-GAADLARL---AELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAFR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 GKGVVPDNHPYCVG----------AARSRAlqfADVIVLFGARLNWILHFGL----PPRyqPDVKFIQVDICAEELGNNV 288
Cdd:PRK08199 241 RQDLFDNRHPNYAGdlglginpalAARIRE---ADLVLAVGTRLGEVTTQGYtlldIPV--PRQTLVHVHPDAEELGRVY 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 289 KPAVTllgnIHAVTKQLLEELDKtpWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNyyTVFYHVQEQLPRDcFVV 368
Cdd:PRK08199 316 RPDLA----IVADPAAFAAALAA--LEPPASPAWAEWTAAAHADYLAWSAPLPGPGAVQLG--EVMAWLRERLPAD-AII 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 369 SEGAntmdiGR--TVLQNYLPRHRLD---AGTFGTMGVGLgfaiAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICR 443
Cdd:PRK08199 387 TNGA-----GNyaTWLHRFFRFRRYRtqlAPTSGSMGYGL----PAAIAAKLLFPERTVVAFAGDGCFLMNGQELATAVQ 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 444 YNLPIILLVVnNNGIYQGFDTDTWKEMLKFQDATAvvppmclLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTT 523
Cdd:PRK08199 458 YGLPIIVIVV-NNGMYGTIRMHQEREYPGRVSGTD-------LTNPDFAALARAYGGHGETVERTEDFAPAFERALA-SG 528
|
570
....*....|...
gi 548923731 524 KPSLINIMIEPQA 536
Cdd:PRK08199 529 KPALIEIRIDPEA 541
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
16-455 |
4.93e-36 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 141.56 E-value: 4.93e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 16 GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAAcyAASAIGY----------------------- 72
Cdd:PRK08978 3 GAQWVVHALRAQGVDTVFGYPGGAIMPVYDALYDGGVEHLLCRHEQGA--AMAAIGYaratgkvgvciatsgpgatnlit 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 73 ------LTSRPLLVIGG--SSErnqeTMG--AFQE---FPQVEACrlyTKFSARPSSIEAIPFVIEKAVRSSIYGRPGAC 139
Cdd:PRK08978 81 gladalLDSVPVVAITGqvSSP----LIGtdAFQEidvLGLSLAC---TKHSFLVQSLEELPEIMAEAFEIASSGRPGPV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 140 YVDIPADfvnLQVNVNSIK-YMERCMSPPisMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFL 218
Cdd:PRK08978 154 LVDIPKD---IQLAEGELEpHLTTVENEP--AFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 219 PTPMGKGVVPDNHPYCVG--------AArSRALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKFIQVDICAEELG 285
Cdd:PRK08978 229 ATLKGLGAVEADHPYYLGmlgmhgtkAA-NLAVQECDLLIAVGAR------FddrvtGKLNTFAPHAKVIHLDIDPAEIN 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 286 NNVKPAVTLLGNIHAVTKQLLEELDKTPWQyppesKWWKTLREKMKSNEAASKELASKKSLpmnyytvFYHVQEQLPRDC 365
Cdd:PRK08978 302 KLRQAHVALQGDLNALLPALQQPLNIDAWR-----QHCAQLRAEHAWRYDHPGEAIYAPAL-------LKQLSDRKPADT 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 366 FVvseganTMDIGRT---VLQNYL---PRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAFGFSGMEVE 439
Cdd:PRK08978 370 VV------TTDVGQHqmwVAQHMRftrPENFITSSGLGTMGFGLPAAIGAQVA----RPDDTVICVSGDGSFMMNVQELG 439
|
490
....*....|....*.
gi 548923731 440 TICRYNLPIILLVVNN 455
Cdd:PRK08978 440 TIKRKQLPVKIVLLDN 455
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
12-455 |
1.19e-34 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 138.19 E-value: 1.19e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVG---IPVTEIAIAAQQLgiKYIGMRNEQAACYAAS-------------------- 68
Cdd:PRK07789 29 ERMTGAQAVVRSLEELGVDVVFGIPGgaiLPVYDPLFDSTKV--RHVLVRHEQGAGHAAEgyaqatgrvgvcmatsgpga 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -------AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYV 141
Cdd:PRK07789 107 tnlvtpiADANMDSVPVVAITGQVGRGLIGTDAFQEADIVGITMPITKHNFLVTDADDIPRVIAEAFHIASTGRPGPVLV 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 142 DIPADFVNLQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 221
Cdd:PRK07789 187 DIPKDALQAQTTFSWPPRMDLPGYRPVTKPHGKQIREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 222 MGKGVVPDNHPYCVG-------AARSRALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKFIQVDICAEELGNNVK 289
Cdd:PRK07789 267 MARGAFPDSHPQHLGmpgmhgtVAAVAALQRSDLLIALGAR------FddrvtGKLDSFAPDAKVIHADIDPAEIGKNRH 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 290 PAVTLLGNIHAVTKQLLEEL--DKTPWQYPPESKWWKTLReKMKSNEAASKELASKKSL-PMnyytvfyHVQEQL----- 361
Cdd:PRK07789 341 ADVPIVGDVKEVIAELIAALraEHAAGGKPDLTAWWAYLD-GWRETYPLGYDEPSDGSLaPQ-------YVIERLgeiag 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 362 PRDCFVVSEGANTMDIGRTVlqNY-LPRHRLDAGTFGTMgvglGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVET 440
Cdd:PRK07789 413 PDAIYVAGVGQHQMWAAQFI--DYeKPRTWLNSGGLGTM----GYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELAT 486
|
490
....*....|....*
gi 548923731 441 ICRYNLPIILLVVNN 455
Cdd:PRK07789 487 CAIEGIPIKVALINN 501
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
19-145 |
1.45e-34 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 127.65 E-value: 1.45e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 19 VIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSR---------------------- 76
Cdd:cd07035 2 ALVEALKAEGVDHVFGVPGGAILPLLDALARSGIRYILVRHEQGAVGMADGYARATGKpgvvlvtsgpgltnavtglana 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 548923731 77 -----PLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPA 145
Cdd:cd07035 82 yldsiPLLVITGQRPTAGEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLPK 155
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
9-534 |
1.50e-33 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 134.50 E-value: 1.50e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 9 RSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPLLVIG--GSSE 86
Cdd:PRK07710 11 TEEKLMTGAQMLIEALEKEGVEVIFGYPGGAVLPLYDALYDCGIPHILTRHEQGAIHAAEGYARISGKPGVVIAtsGPGA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 87 RNQET-----------------------MG--AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYV 141
Cdd:PRK07710 91 TNVVTgladamidslplvvftgqvatsvIGsdAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPVLI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 142 DIPADFVNLQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 221
Cdd:PRK07710 171 DIPKDMVVEEGEFCYDVQMDLPGYQPNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQEIPVVHTL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 222 MGKGVVPDNHPYCVGAA-------RSRALQFADVIVLFGARLNWILHFGLpPRYQPDVKFIQVDICAEELGNNVKPAVTL 294
Cdd:PRK07710 251 LGLGGFPADHPLFLGMAgmhgtytANMALYECDLLINIGARFDDRVTGNL-AYFAKEATVAHIDIDPAEIGKNVPTEIPI 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 295 LGNIHAVTKQLLEELDKtpwqyPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHvqeqlprdcFVVSEGANT 374
Cdd:PRK07710 330 VADAKQALQVLLQQEGK-----KENHHEWLSLLKNWKEKYPLSYKRNSESIKPQKAIEMLYE---------ITKGEAIVT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 375 MDIGRTVL--QNYLPRHRLD----AGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPI 448
Cdd:PRK07710 396 TDVGQHQMwaAQYYPFKTPDkwvtSGGLGTMGFGLPAAIGAQLAKPDET----VVAIVGDGGFQMTLQELSVIKELSLPV 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 449 ILLVVNNNGIYQgfdTDTWKEMLKFQDATAvvppmCLLPNS-HYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSL 527
Cdd:PRK07710 472 KVVILNNEALGM---VRQWQEEFYNQRYSH-----SLLSCQpDFVKLAEAYGIKGVRIDDELEAKEQLQHAIE-LQEPVV 542
|
....*..
gi 548923731 528 INIMIEP 534
Cdd:PRK07710 543 IDCRVLQ 549
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
10-523 |
1.93e-33 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 134.55 E-value: 1.93e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 10 SEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAA-QQLGIKYIGMRNEQAACYAAS-------------------- 68
Cdd:PRK06965 17 PAADSIGAEILMKALAAEGVEFIWGYPGGAVLYIYDELyKQDKIQHVLVRHEQAAVHAADgyaratgkvgvalvtsgpgv 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 69 -------AIGYLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYV 141
Cdd:PRK06965 97 tnavtgiATAYMDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFYIARTGRPGPVVV 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 142 DIPADfvnlqVNVNSIKY-----MERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLP 216
Cdd:PRK06965 177 DIPKD-----VSKTPCEYeypksVEMRSYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELRQLADLLGYP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 217 FLPTPMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWIL-----HFGLPPRyqpdvKFIQVDICAEEL 284
Cdd:PRK06965 252 VTNTLMGLGAYPASDKKFLGMlgmhgtyEANMAMQHCDVLIAIGARFDDRVignpaHFASRPR-----KIIHIDIDPSSI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 285 GNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPE--SKWWKTLrEKMKSNEAASKELASKKSLPMnyytvfyHVQEQL- 361
Cdd:PRK06965 327 SKRVKVDIPIVGDVKEVLKELIEQLQTAEHGPDADalAQWWKQI-EGWRSRDCLKYDRESEIIKPQ-------YVVEKLw 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 362 ---PRDCFVVSegantmDIGRTVL---QNYL---PRHRLDAGTFGTMGVGLGFAIAAavvaKDRSPGQWIICVEGDSAFG 432
Cdd:PRK06965 399 eltDGDAFVCS------DVGQHQMwaaQFYRfnePRRWINSGGLGTMGVGLPYAMGI----KMAHPDDDVVCITGEGSIQ 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 433 FSGMEVETICRYNLPIILLVVNNNgiYQGFdTDTWKEM-------LKFQDAtavvppmclLPNshYEQVMTAFGGKGYFV 505
Cdd:PRK06965 469 MCIQELSTCLQYDTPVKIISLNNR--YLGM-VRQWQEIeyskrysHSYMDA---------LPD--FVKLAEAYGHVGMRI 534
|
570 580
....*....|....*....|
gi 548923731 506 QTPEELQKSLRQS--LADTT 523
Cdd:PRK06965 535 EKTSDVEPALREAlrLKDRT 554
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
15-537 |
2.43e-32 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 130.72 E-value: 2.43e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 15 SGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPLLVIGGS---------- 84
Cdd:PRK06457 3 SVAEVIIRVLEDNGIQRIYGIPGDSIDPLVDAIRKSKVKYVQVRHEEGAALAASVEAKITGKPSACMGTSgpgsihllng 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 85 --------------SERNQETMGAFQEFPQVEACRLY---TKFSARPSSIEAIPFVIEKAVRSSIYGRpGACYVDIPADF 147
Cdd:PRK06457 83 lydakmdhapvialTGQVESDMIGHDYFQEVNLTKLFddvAVFNQILINPENAEYIIRRAIREAISKR-GVAHINLPVDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 148 VNLQVNVNSIKYMERC---MSPPISMAEtsavctaaSVIRNAKQPLLIIGKGAAyAHAEEsIKKLVEQYKLPFLPTPMGK 224
Cdd:PRK06457 162 LRKSSEYKGSKNTEVGkvkYSIDFSRAK--------ELIKESEKPVLLIGGGTR-GLGKE-INRFAEKIGAPIIYTLNGK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 225 GVVPDNHPYCVGA-------ARSRALQFADVIVLFGARLNWILHFglppryQPDVKFIQVDICAEELGNNVKPAVTLLGN 297
Cdd:PRK06457 232 GILPDLDPKVMGGigllgtkPSIEAMDKADLLIMLGTSFPYVNFL------NKSAKVIQVDIDNSNIGKRLDVDLSYPIP 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 298 ihaVTKQLLEELDKTPWQYPPESKwwktlREKMKSNEAASKeLASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGAN-TMd 376
Cdd:PRK06457 306 ---VAEFLNIDIEEKSDKFYEELK-----GKKEDWLDSISK-QENSLDKPMKPQRVAYIVSQKCKKDAVIVTDTGNvTM- 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 377 igrtvlqnYLPRHRLDAG--TF------GTMGVGLGFAIAAAVVAKDRspgQWIICVEGDSAFGFSGMEVETICRYNLPI 448
Cdd:PRK06457 376 --------WTARHFRASGeqTFifsawlGSMGIGVPGSVGASFAVENK---RQVISFVGDGGFTMTMMELITAKKYDLPV 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 449 ILLVVNNNGIyqgfdtdtwkEMLKFQDATAVVPPMCL-LPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLaDTTKPSL 527
Cdd:PRK06457 445 KIIIYNNSKL----------GMIKFEQEVMGYPEWGVdLYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFL-NTKGPAV 513
|
570
....*....|
gi 548923731 528 INIMIEPQAT 537
Cdd:PRK06457 514 LDAIVDPNER 523
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
20-535 |
5.16e-32 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 129.51 E-value: 5.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 20 IAQALKTQDVEYIFGIVGIPVTEI--AIAAQQlGIKYIGMRNEQAACYAA---------------------SAI-----G 71
Cdd:COG3961 11 LLDRLAELGIRHIFGVPGDYNLPFldAIEAHP-GIRWVGCCNELNAGYAAdgyarvnglgalvttygvgelSAIngiagA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 72 YLTSRPLLVIGG---SSERNQETM-------GAFQEFpqveaCRLYTKFSARPSSIEA------IPFVIEKAVRssiYGR 135
Cdd:COG3961 90 YAERVPVVHIVGapgTRAQRRGPLlhhtlgdGDFDHF-----LRMFEEVTVAQAVLTPenaaaeIDRVLAAALR---EKR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 136 PGacYVDIPADFVNLQVNVNSIKYMercMSPPISMAET--SAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQY 213
Cdd:COG3961 162 PV--YIELPRDVADAPIEPPEAPLP---LPPPASDPAAlaAAVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAEKT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 214 KLPFLPTPMGKGVVPDNHPYCVG-----AARSRALQF---ADVIVLFGARLN----WILHFGLPPRyqpdvKFIQVDICA 281
Cdd:COG3961 237 GIPVATTLLGKSVLDESHPQFIGtyagaASSPEVREYvenADCVLCLGVVFTdtntGGFTAQLDPE-----RTIDIQPDS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 282 EELGNNVKPAVTLlgniHAVTKQLLEELDKTPWQYPPESKwwktlreKMKSNEAASKElaskkslPMNYYTVFYHVQEQL 361
Cdd:COG3961 312 VRVGGHIYPGVSL----ADFLEALAELLKKRSAPLPAPAP-------PPPPPPAAPDA-------PLTQDRLWQRLQAFL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 362 PRDCFVVSE------GANTMDI--GRTVL-QNYlprhrldagtFGTMGVGLGFAIAAAVVAKDRSPgqwIICVeGDSAFG 432
Cdd:COG3961 374 DPGDIVVADtgtslfGAADLRLpeGATFIaQPL----------WGSIGYTLPAALGAALAAPDRRV---ILLV-GDGAFQ 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 433 FSGMEVETICRYNLPIILLVVNNNG-----IYQGFDTDtwkemlkFQDatavvppmclLPNSHYEQVMTAFGGKGYF--- 504
Cdd:COG3961 440 LTAQELSTMLRYGLKPIIFVLNNDGytierAIHGPDGP-------YND----------IANWDYAKLPEAFGGGNALgfr 502
|
570 580 590
....*....|....*....|....*....|.
gi 548923731 505 VQTPEELQKSLRQSLADTTKPSLINIMIEPQ 535
Cdd:COG3961 503 VTTEGELEEALAAAEANTDRLTLIEVVLDKM 533
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
2-455 |
1.06e-31 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 129.09 E-value: 1.06e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 2 PDSNFAErsEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIA-AQQLGIKYIGMRNEQAACYAASaiGY-------- 72
Cdd:PLN02470 3 FQSRFAP--DEPRKGADILVEALEREGVDTVFAYPGGASMEIHQAlTRSNCIRNVLCRHEQGEVFAAE--GYakasgkvg 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 73 ---------------------LTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSS 131
Cdd:PLN02470 79 vciatsgpgatnlvtgladalLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 132 IYGRPGACYVDIPADfVNLQVNV----NSIK---YMERCMSPPismaETSAVCTAASVIRNAKQPLLIIGKGAayAHAEE 204
Cdd:PLN02470 159 SSGRPGPVLVDIPKD-IQQQLAVpnwnQPMKlpgYLSRLPKPP----EKSQLEQIVRLISESKRPVVYVGGGC--LNSSE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 205 SIKKLVEQYKLPFLPTPMGKGVVPDNHPYCV------GAARSR-ALQFADVIVLFGARLNWILHfGLPPRYQPDVKFIQV 277
Cdd:PLN02470 232 ELREFVELTGIPVASTLMGLGAFPASDELSLqmlgmhGTVYANyAVDSADLLLAFGVRFDDRVT-GKLEAFASRASIVHI 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 278 DICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKmksneaaskelasKKSLPMNYYTVF--- 354
Cdd:PLN02470 311 DIDPAEIGKNKQPHVSVCADVKLALQGLNKLLEERKAKRPDFSAWRAELDEQ-------------KEKFPLSYPTFGdai 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 355 ---YHVQ--EQLPRDCFVVSEGANTMDIGRTVLQNY-LPRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGD 428
Cdd:PLN02470 378 ppqYAIQvlDELTDGNAIISTGVGQHQMWAAQWYKYkEPRRWLTSGGLGAMGFGLPAAIGAAAA----NPDAIVVDIDGD 453
|
490 500
....*....|....*....|....*..
gi 548923731 429 SAFGFSGMEVETICRYNLPIILLVVNN 455
Cdd:PLN02470 454 GSFIMNIQELATIHVENLPVKIMVLNN 480
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
357-532 |
6.63e-31 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 118.13 E-value: 6.63e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 357 VQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGM 436
Cdd:cd00568 6 LRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRP----VVCIAGDGGFMMTGQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 437 EVETICRYNLPIILlVVNNNGIYQgfdtDTWKEMLKFQDATavvPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLR 516
Cdd:cd00568 82 ELATAVRYGLPVIV-VVFNNGGYG----TIRMHQEAFYGGR---VSGTDLSNPDFAALAEAYGAKGVRVEDPEDLEAALA 153
|
170
....*....|....*.
gi 548923731 517 QSLAdTTKPSLINIMI 532
Cdd:cd00568 154 EALA-AGGPALIEVKT 168
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
371-530 |
2.88e-30 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 115.76 E-value: 2.88e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 371 GANTMDIGRtVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPIIL 450
Cdd:pfam02775 3 GCHQMWAAQ-YYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRP----VVAIAGDGGFQMNLQELATAVRYNLPITV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 451 LVVNNNGiyQGFdTDTWKEMlkFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLINI 530
Cdd:pfam02775 78 VVLNNGG--YGM-TRGQQTP--FGGGRYSGPSGKILPPVDFAKLAEAYGAKGARVESPEELEEALKEALE-HDGPALIDV 151
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
12-533 |
4.55e-29 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 121.35 E-value: 4.55e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAA-QQLGIKYIGMRNEQAACYAASAIGYLTSRP--LLVIGGSSERN 88
Cdd:PRK09107 9 RQMTGAEMVVQALKDQGVEHIFGYPGGAVLPIYDEIfQQDDIQHILVRHEQGAGHAAEGYARSTGKPgvVLVTSGPGATN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 89 QET-----------------------MG--AFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDI 143
Cdd:PRK09107 89 AVTplqdalmdsiplvcitgqvpthlIGsdAFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSGRPGPVVVDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 144 PAD-------FVNLQVNVNSIKYmercmsPPISMAETSAVCTAASVIRNAKQPLLIIGKGA--AYAHAEESIKKLVEQYK 214
Cdd:PRK09107 169 PKDvqfatgtYTPPQKAPVHVSY------QPKVKGDAEAITEAVELLANAKRPVIYSGGGVinSGPEASRLLRELVELTG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 215 LPFLPTPMGKGVVPDNHPYCVGA-------ARSRALQFADVIVLFGARlnwilhF-----GLPPRYQPDVKFIQVDICAE 282
Cdd:PRK09107 243 FPITSTLMGLGAYPASGKNWLGMlgmhgtyEANMAMHDCDVMLCVGAR------FddritGRLDAFSPNSKKIHIDIDPS 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 283 ELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPE--SKWWKTLREKMKSNEAASKElasKKSLPMNYYTVfyhvqEQ 360
Cdd:PRK09107 317 SINKNVRVDVPIIGDVGHVLEDMLRLWKARGKKPDKEalADWWGQIARWRARNSLAYTP---SDDVIMPQYAI-----QR 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 361 L-----PRDCFVVSE-GANTMdigrTVLQNY---LPRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAF 431
Cdd:PRK09107 389 LyeltkGRDTYITTEvGQHQM----WAAQFFgfeEPNRWMTSGGLGTMGYGLPAALGVQIA----HPDALVIDIAGDASI 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 432 GFSGMEVETICRYNLPIILLVVNNNgiYQGFdTDTWKEML-------KFQDAtavvppmclLPNshYEQVMTAFGGKGYF 504
Cdd:PRK09107 461 QMCIQEMSTAVQYNLPVKIFILNNQ--YMGM-VRQWQQLLhgnrlshSYTEA---------MPD--FVKLAEAYGAVGIR 526
|
570 580
....*....|....*....|....*....
gi 548923731 505 VQTPEELQKSLRQSLaDTTKPSLINIMIE 533
Cdd:PRK09107 527 CEKPGDLDDAIQEMI-DVDKPVIFDCRVA 554
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
16-153 |
1.68e-28 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 111.17 E-value: 1.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 16 GAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQ-QLGIKYIGMRNEQAACYAASAIGYLT-------------------- 74
Cdd:pfam02776 1 GAEALADVLKALGVDTVFGVPGGHILPLLDALAkSPGIRYVLTRHEQGAAFAADGYARATgkpgvvlvtsgpgatnaltg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 75 -------SRPLLVIGGSSERNQETMGAFQ-EFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPAD 146
Cdd:pfam02776 81 lanayvdSVPLLVISGQRPRSLVGRGALQqELDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPLD 160
|
....*..
gi 548923731 147 FVNLQVN 153
Cdd:pfam02776 161 VLLEEVD 167
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
12-457 |
7.08e-27 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 114.32 E-value: 7.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 12 EQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIA-AQQLGIKYIGMRNEQAACYAASAIGY--------LTS------- 75
Cdd:PRK07064 1 EKVTVGELIAAFLEQCGVKTAFGVISIHNMPILDAiGRRGKIRFVPARGEAGAVNMADAHARvsgglgvaLTStgtgagn 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 76 ------------RPLLVIGGSSERN--QETMGAFQEFP-QVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACY 140
Cdd:PRK07064 81 aagalvealtagTPLLHITGQIETPylDQDLGYIHEAPdQLTMLRAVSKAAFRVRSAETALATIREAVRVALTAPTGPVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 141 VDIPADfvnlqvnvnsIKYMERCMS-------PPISMAETSAVCTAASVIRNAKQPLLIIGKGAayAHAEESIKKLVEqY 213
Cdd:PRK07064 161 VEIPID----------IQAAEIELPddlapvhVAVPEPDAAAVAELAERLAAARRPLLWLGGGA--RHAGAEVKRLVD-L 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 214 KLPFLPTPMGKGVVPDNHPYCVGA----ARSRAL-QFADVIVLFGARL--NWILHFGLP-PRyqpdvKFIQVDICAEELG 285
Cdd:PRK07064 228 GFGVVTSTQGRGVVPEDHPASLGAfnnsAAVEALyKTCDLLLVVGSRLrgNETLKYSLAlPR-----PLIRVDADAAADG 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 286 NNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPpesKWWKTLREKMKSNEAA-SKELASKKSLPmnyytvfYHVQEQLPRD 364
Cdd:PRK07064 303 RGYPNDLFVHGDAARVLARLADRLEGRLSVDP---AFAADLRAAREAAVADlRKGLGPYAKLV-------DALRAALPRD 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 365 CFVVSegantmDI---GRTVLQNYLPRHRLDAGTF---GTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAFGFSGMEV 438
Cdd:PRK07064 373 GNWVR------DVtisNSTWGNRLLPIFEPRANVHalgGGIGQGLAMAIGAALA----GPGRKTVGLVGDGGLMLNLGEL 442
|
490
....*....|....*....
gi 548923731 439 ETICRYNLPIILLVVNNNG 457
Cdd:PRK07064 443 ATAVQENANMVIVLMNDGG 461
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
65-533 |
6.36e-25 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 108.91 E-value: 6.36e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 65 YAASAigylTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIP 144
Cdd:PRK11269 88 YSASA----DSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLP 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 145 ADfvnlqVNVNSIKYMERCMSP-PISMAETS--AVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 221
Cdd:PRK11269 164 FD-----VQVAEIEFDPDTYEPlPVYKPAATraQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIPTL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 222 MGKGVVPDNHPYCVGAArsrALQFA-----------DVIVLFGARlnWI-LHFGLPPRYQPDVKFIQVDICAEELGNNVK 289
Cdd:PRK11269 239 MGWGAIPDDHPLMAGMV---GLQTShrygnatllasDFVLGIGNR--WAnRHTGSVEVYTKGRKFVHVDIEPTQIGRVFG 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 290 PAVTLLGNIHAVTKQLLEELD--KTPWQYPPESKWWKTLREKmksneaasKELASKKS----LPMNYYTVFYHVQEQLPR 363
Cdd:PRK11269 314 PDLGIVSDAKAALELLVEVARewKAAGRLPDRSAWVADCQER--------KRTLLRKThfdnVPIKPQRVYEEMNKAFGR 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 364 D-CFVVSEGANTMdIGRTVLQNYLPRHRLDAGTFGTmgvgLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETIC 442
Cdd:PRK11269 386 DtCYVSTIGLSQI-AAAQFLHVYKPRHWINCGQAGP----LGWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELAVGA 460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 443 RYNLPIILLVVNNN--G-IYQ---GFDTDtWKEMLKFQDATAvvPPMCLLPNSHYeQVMTAFGGKGYFVQTPEELQKSLR 516
Cdd:PRK11269 461 QFNLPYIHVLVNNAylGlIRQaqrAFDMD-YCVQLAFENINS--PELNGYGVDHV-KVAEGLGCKAIRVFKPEDIAPALE 536
|
490 500
....*....|....*....|
gi 548923731 517 QS---LADTTKPSLINIMIE 533
Cdd:PRK11269 537 QAkalMAEFRVPVVVEVILE 556
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
17-536 |
7.20e-24 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 105.46 E-value: 7.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 17 AKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQ-LGIKYIGMRNEQAACYAASAIGYLTSR------------------- 76
Cdd:PRK06546 6 AEQLVEQLVAAGVKRIYGIVGDSLNPIVDAVRRtGGIEWVHVRHEEAAAFAAAAEAQLTGKlavcagscgpgnlhlingl 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 77 --------PLLVIGGSSERNQETMGAFQE-FPQveacRLYTK---FSARPSSIEAIPFVIEKAVRSSIyGRPGACYVDIP 144
Cdd:PRK06546 86 ydahrsgaPVLAIASHIPSAQIGSGFFQEtHPD----RLFVEcsgYCEMVSSAEQAPRVLHSAIQHAV-AGGGVSVVTLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 145 ADFVNLQVNVNSIKYMERCmSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEesIKKLVEQYKLPFLPTPMGK 224
Cdd:PRK06546 161 GDIADEPAPEGFAPSVISP-RRPTVVPDPAEVRALADAINEAKKVTLFAGAGVRGAHAE--VLALAEKIKAPVGHSLRGK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 225 GVVPDNHPYCVG-------AARSRALQFADVIVLFGARLnwilhfglpPRYQ--PDVKFIQVDICAEELGNNVKPAVTLL 295
Cdd:PRK06546 238 EWIQYDNPFDVGmsgllgyGAAHEAMHEADLLILLGTDF---------PYDQflPDVRTAQVDIDPEHLGRRTRVDLAVH 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 296 GNIHAVTKQLLEELD-KTPWQYPPeskwwKTLREKMKSNEAASKELASK--KSLPMNYYTVFYHVQEQLPRDC-FVVSEG 371
Cdd:PRK06546 309 GDVAETIRALLPLVKeKTDRRFLD-----RMLKKHARKLEKVVGAYTRKveKHTPIHPEYVASILDELAADDAvFTVDTG 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 372 ANTMDIGRTVLQNylPRHRLdAGTF--GTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAFGFSGMEVETICRYNLPII 449
Cdd:PRK06546 384 MCNVWAARYITPN--GRRRV-IGSFrhGSMANALPHAIGAQLA----DPGRQVISMSGDGGLSMLLGELLTVKLYDLPVK 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 450 LLVVNNNGIyqgfdtdtwkEMLKFQDATAVVPPMCL-LPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLI 528
Cdd:PRK06546 457 VVVFNNSTL----------GMVKLEMLVDGLPDFGTdHPPVDYAAIAAALGIHAVRVEDPKDVRGALREAFA-HPGPALV 525
|
....*...
gi 548923731 529 NIMIEPQA 536
Cdd:PRK06546 526 DVVTDPNA 533
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
17-535 |
7.82e-24 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 105.46 E-value: 7.82e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 17 AKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLG-IKYIGMRNEQAACYAASAIGYLTSRpLLVIGGS----------- 84
Cdd:PRK09124 6 ADYIAKTLEQAGVKRIWGVTGDSLNGLSDSLRRMGtIEWMHTRHEEVAAFAAGAEAQLTGE-LAVCAGScgpgnlhling 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 85 ---SERNQETM--------------GAFQE-FPQ--VEACRLYTKFSARPssiEAIPFVIEKAVRSSIyGRPGACYVDIP 144
Cdd:PRK09124 85 lfdCHRNHVPVlaiaahipsseigsGYFQEtHPQelFRECSHYCELVSNP---EQLPRVLAIAMRKAI-LNRGVAVVVLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 145 ADfVNLQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEesIKKLVEQYKLPFLPTPMGK 224
Cdd:PRK09124 161 GD-VALKPAPERATPHWYHAPQPVVTPAEEELRKLAALLNGSSNITLLCGSGCAGAHDE--LVALAETLKAPIVHALRGK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 225 GVVPDNHPYCVG-------AARSRALQFADVIVLFGARlnwilhFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGN 297
Cdd:PRK09124 238 EHVEYDNPYDVGmtgligfSSGYHAMMNCDTLLMLGTD------FPYRQFYPTDAKIIQIDINPGSLGRRSPVDLGLVGD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 298 IHAVTKQLLEELD-KTPWQYppeskwwktLREKMKSNEAASKEL-----ASKKSLPMnyytvfyHVQeQLPRdcfVVSEG 371
Cdd:PRK09124 312 VKATLAALLPLLEeKTDRKF---------LDKALEHYRKARKGLddlavPSDGGKPI-------HPQ-YLAR---QISEF 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 372 AN-----TMDIGRTVL--QNYLP---RHRLdAGTF--GTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSafGFSGM--E 437
Cdd:PRK09124 372 AAddaifTCDVGTPTVwaARYLKmngKRRL-LGSFnhGSMANAMPQALGAQAAHPGRQ----VVALSGDG--GFSMLmgD 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 438 VETICRYNLPIILLVVNNNGIyqGFdtdTWKEMlkfqDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQ 517
Cdd:PRK09124 445 FLSLVQLKLPVKIVVFNNSVL--GF---VAMEM----KAGGYLTDGTDLHNPDFAAIAEACGITGIRVEKASELDGALQR 515
|
570
....*....|....*...
gi 548923731 518 SLAdTTKPSLINIMIEPQ 535
Cdd:PRK09124 516 AFA-HDGPALVDVVTAKQ 532
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
77-533 |
8.70e-23 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 101.96 E-value: 8.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 77 PLLVIGGSSERN---QETM-GAFQ--EFPqveacRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADfvnl 150
Cdd:PRK07092 101 PLVITAGQQARSilpFEPFlAAVQaaELP-----KPYVKWSIEPARAEDVPAAIARAYHIAMQPPRGPVFVSIPYD---- 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 151 qvnvnsiKYMERCmsPPISMAETSAVC--------TAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 222
Cdd:PRK07092 172 -------DWDQPA--EPLPARTVSSAVrpdpaalaRLGDALDAARRPALVVGPAVDRAGAWDDAVRLAERHRAPVWVAPM 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 223 -GKGVVPDNHPYCVG---AAR---SRALQFADVIVLFGARLNwILHFGLPPRYQPD-VKFIQVDICAEELGnnVKPAVT- 293
Cdd:PRK07092 243 sGRCSFPEDHPLFAGflpASRekiSALLDGHDLVLVIGAPVF-TYHVEGPGPHLPEgAELVQLTDDPGEAA--WAPMGDa 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 294 LLGNIHAVTKQLLEELDKTPWQYPPEskwwktlREKMKSNEAASKelaskkslPMNYYTVFYHVQEQLPRDCFVVSEGAN 373
Cdd:PRK07092 320 IVGDIRLALRDLLALLPPSARPAPPA-------RPMPPPAPAPGE--------PLSVAFVLQTLAALRPADAIVVEEAPS 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 374 TmdigRTVLQNYLPRHRldAGTFGTMGVG-LGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLV 452
Cdd:PRK07092 385 T----RPAMQEHLPMRR--QGSFYTMASGgLGYGLPAAVGVALAQPGRRVIGLIGDGSAMYSIQALWSAAQLKLPVTFVI 458
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 453 VNNN--GIYQGFDTdtwkeMLKFQDAtavvpPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADtTKPSLINI 530
Cdd:PRK07092 459 LNNGryGALRWFAP-----VFGVRDV-----PGLDLPGLDFVALARGYGCEAVRVSDAAELADALARALAA-DGPVLVEV 527
|
...
gi 548923731 531 MIE 533
Cdd:PRK07092 528 EVA 530
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
14-524 |
1.17e-22 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 101.62 E-value: 1.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 14 VSGAKVIAQALKTQDVEYIFGIVG---IPVTEIAIAAQQLGIK---YIGMRNEQAAcyAASAIGY--------------- 72
Cdd:PRK08327 7 YTAAELFLELLKELGVDYIFINSGtdyPPIIEAKARARAAGRPlpeFVICPHEIVA--ISMAHGYalvtgkpqavmvhvd 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 73 -------------LTSR-PLLVIGGSSERNQEtmGAF----------QE-FPQVEACRLYTKFSARPSSIEAIPFVIEKA 127
Cdd:PRK08327 85 vgtanalggvhnaARSRiPVLVFAGRSPYTEE--GELgsrntrihwtQEmRDQGGLVREYVKWDYEIRRGDQIGEVVARA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 128 VRSSIYGRPGACYVDIPADFVNLQVNVNSIkYMERCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIK 207
Cdd:PRK08327 163 IQIAMSEPKGPVYLTLPREVLAEEVPEVKA-DAGRQMAPAPPAPDPEDIARAAEMLAAAERPVIITWRAGRTAEGFASLR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 208 KLVEQYKLP---FLPTPMgkgVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPryqPDVKFIQVDIcaeel 284
Cdd:PRK08327 242 RLAEELAIPvveYAGEVV---NYPSDHPLHLGPDPRADLAEADLVLVVDSDVPWIPKKIRPD---ADARVIQIDV----- 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 285 gNNVKPAVTLLG-----NIHAVTK---QLLEELDKTPWQYPPESKWWKTLREKMKSNEAASKELASKKSL----PMNYYT 352
Cdd:PRK08327 311 -DPLKSRIPLWGfpcdlCIQADTStalDQLEERLKSLASAERRRARRRRAAVRELRIRQEAAKRAEIERLkdrgPITPAY 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 353 VFYHVQEQLPRDCFVVSEgantmdigRTVLQNYLPRHRldAGTFGTMGV--GLGFAIAAAVVAKDRSPGQWIICVEGDSA 430
Cdd:PRK08327 390 LSYCLGEVADEYDAIVTE--------YPFVPRQARLNK--PGSYFGDGSagGLGWALGAALGAKLATPDRLVIATVGDGS 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 431 FGFSgmeVETIC-----RYNLPiILLVVNNNGIYQGFDTDTwKEMlkFQDATAV----VPPMCLLPNSHYEQVMTAFGGK 501
Cdd:PRK08327 460 FIFG---VPEAAhwvaeRYGLP-VLVVVFNNGGWLAVKEAV-LEV--YPEGYAArkgtFPGTDFDPRPDFAKIAEAFGGY 532
|
570 580
....*....|....*....|...
gi 548923731 502 GYFVQTPEELQKSLRQSLADTTK 524
Cdd:PRK08327 533 GERVEDPEELKGALRRALAAVRK 555
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
346-536 |
4.32e-21 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 91.42 E-value: 4.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 346 LPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGvglgFAIAAAVVAKDRSPGQWIICV 425
Cdd:cd02013 2 NPMHPRQVLRELEKAMPEDAIVSTDIGNICSVANSYLRFEKPRSFIAPLSFGNCG----YALPAIIGAKAAAPDRPVVAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 426 EGDSAFGFSGMEVETICRYNLPIILLVvnnngiyqgFDTDTW----KEMLKFQDATAVVPPmclLPNSHYEQVMTAFGGK 501
Cdd:cd02013 78 AGDGAWGMSMMEIMTAVRHKLPVTAVV---------FRNRQWgaekKNQVDFYNNRFVGTE---LESESFAKIAEACGAK 145
|
170 180 190
....*....|....*....|....*....|....*..
gi 548923731 502 GYFVQTPEELQKSLRQSLADTT--KPSLINIMIEPQA 536
Cdd:cd02013 146 GITVDKPEDVGPALQKAIAMMAegKTTVIEIVCDQEL 182
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
347-536 |
6.56e-21 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 90.28 E-value: 6.56e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 347 PMNYYTVFYHVQEQLPRDC-FVVSEGANTMDIGRtvlqnYLPRHR----LDAGTFGTMGVGLGFAIAAAVVAKDRSpgqw 421
Cdd:cd02014 1 PIHPERVAAELNKRAPDDAiFTIDVGNVTVWAAR-----HLRMNGkqrfILSGLLATMGNGLPGAIAAKLAYPDRQ---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 422 IICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIyqGFdtDTWKEMLKFQDATAVVppmclLPNSHYEQVMTAFGGK 501
Cdd:cd02014 72 VIALSGDGGFAMLMGDLITAVKYNLPVIVVVFNNSDL--GF--IKWEQEVMGQPEFGVD-----LPNPDFAKIAEAMGIK 142
|
170 180 190
....*....|....*....|....*....|....*
gi 548923731 502 GYFVQTPEELQKSLRQSLAdTTKPSLINIMIEPQA 536
Cdd:cd02014 143 GIRVEDPDELEAALDEALA-ADGPVVIDVVTDPNE 176
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
357-536 |
1.73e-19 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 86.40 E-value: 1.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 357 VQEQLPRDCFVVSE-GANTMDIGRTvLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSG 435
Cdd:cd02015 10 LSELTPGDAIVTTDvGQHQMWAAQY-YRFKKPRSWLTSGGLGTMGFGLPAAIGAKVARPDKT----VICIDGDGSFQMNI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 436 MEVETICRYNLPIILLVVNNNgiYQGfdtdtwkeMLK-FQDA------TAVVPPMCllPNshYEQVMTAFGGKGYFVQTP 508
Cdd:cd02015 85 QELATAAQYNLPVKIVILNNG--SLG--------MVRqWQELfyegrySHTTLDSN--PD--FVKLAEAYGIKGLRVEKP 150
|
170 180
....*....|....*....|....*...
gi 548923731 509 EELQKSLRQSLaDTTKPSLINIMIEPQA 536
Cdd:cd02015 151 EELEAALKEAL-ASDGPVLLDVLVDPEE 177
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
353-533 |
5.79e-18 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 81.57 E-value: 5.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 353 VFYHVQEQLPRDCFVVSE-GANTMDIGRtVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAF 431
Cdd:cd02010 4 IVHDLRAVMGDDDIVLLDvGAHKIWMAR-YYRTYAPNTCLISNGLATMGVALPGAIGAKLV----YPDRKVVAVSGDGGF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 432 GFSGMEVETICRYNLPIILLVVNNNgiyqGFDTDTWKEMLKFQDATAVVppmclLPNSHYEQVMTAFGGKGYFVQTPEEL 511
Cdd:cd02010 79 MMNSQELETAVRLKIPLVVLIWNDN----GYGLIKWKQEKEYGRDSGVD-----FGNPDFVKYAESFGAKGYRIESADDL 149
|
170 180
....*....|....*....|..
gi 548923731 512 QKSLRQSLADtTKPSLINIMIE 533
Cdd:cd02010 150 LPVLERALAA-DGVHVIDCPVD 170
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
115-534 |
1.42e-16 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 82.65 E-value: 1.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 115 SSIEAIPFVIEKAVRSSIYGRPGACyVDIPADFVNLQVN---------VNSIKYmercmSPPISMAETSAVCTAASVIRN 185
Cdd:PRK08273 134 TVPEQLRHLVDRAVRTALAERTVTA-VILPNDVQELEYEppphahgtvHSGVGY-----TRPRVVPYDEDLRRAAEVLNA 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 186 AKQPLLIIGKGAAYAHAEesIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVGAarsralqfadvIVLFGARLNW------- 258
Cdd:PRK08273 208 GRKVAILVGAGALGATDE--VIAVAERLGAGVAKALLGKAALPDDLPWVTGS-----------IGLLGTKPSYelmrecd 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 259 -ILHFG--------LPPRYQpdVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTP---WQYPPES---KWW 323
Cdd:PRK08273 275 tLLMVGssfpysefLPKEGQ--ARGVQIDIDGRMLGLRYPMEVNLVGDAAETLRALLPLLERKKdrsWRERIEKwvaRWW 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 324 KTLREKmkSNEAASkelaskkslPMNYYTVFYHVQEQLPRDCFVvseganTMDIGRTVlqNYLPRH---RLDA-----GT 395
Cdd:PRK08273 353 ETLEAR--AMVPAD---------PVNPQRVFWELSPRLPDNAIL------TADSGSCA--NWYARDlrmRRGMmaslsGT 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 396 FGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGM-EVETICRY-----NLPIILLVVNNNGIYQgfdtDTW-- 467
Cdd:PRK08273 414 LATMGPAVPYAIAAKFAHPDRP----VIALVGDGAMQMNGMaELITVAKYwrqwsDPRLIVLVLNNRDLNQ----VTWeq 485
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 468 KEML---KFQDATAvvppmclLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLAdTTKPSLINIMIEP 534
Cdd:PRK08273 486 RVMEgdpKFEASQD-------LPDVPYARFAELLGLKGIRVDDPEQLGAAWDEALA-ADRPVVLEVKTDP 547
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
394-534 |
2.19e-15 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 74.49 E-value: 2.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 394 GTFGTMGVGLGFAIAAAVVAKDRSPgqwiICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGiYqgfdtdtwkEMLK- 472
Cdd:cd02005 47 PLWGSIGYSVPAALGAALAAPDRRV----ILLVGDGSFQMTVQELSTMIRYGLNPIIFLINNDG-Y---------TIERa 112
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 548923731 473 FQDATA---VVPPMcllpnsHYEQVMTAFG----GKGYFVQTPEELQKSLRQSLADTTKPSLINIMIEP 534
Cdd:cd02005 113 IHGPEAsynDIANW------NYTKLPEVFGggggGLSFRVKTEGELDEALKDALFNRDKLSLIEVILPK 175
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
348-532 |
2.60e-15 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 74.17 E-value: 2.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 348 MNYYTVFYHVQEQLPRDCFVVSEGANTmdigRTVLQNYLPRHRLDaGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEG 427
Cdd:cd02002 1 LTPEYLAAALAAALPEDAIIVDEAVTN----GLPLRDQLPLTRPG-SYFTLRGGGLGWGLPAAVGAALANPDRKVVAIIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 428 DSAFGFSGMEVETICRYNLPIILLVVNNNG--IYQGFDTDTWKEMLKFQdatAVVPPMCLLPNSHYEQVMTAFGGKGYFV 505
Cdd:cd02002 76 DGSFMYTIQALWTAARYGLPVTVVILNNRGygALRSFLKRVGPEGPGEN---APDGLDLLDPGIDFAAIAKAFGVEAERV 152
|
170 180
....*....|....*....|....*..
gi 548923731 506 QTPEELQKSLRQSLADtTKPSLINIMI 532
Cdd:cd02002 153 ETPEELDEALREALAE-GGPALIEVVV 178
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
17-147 |
1.32e-13 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 68.73 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 17 AKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQ-QLGIKYIGMRNEQAACYAASAIGYLTSR------------------- 76
Cdd:cd07039 3 ADVIVETLENWGVKRVYGIPGDSINGLMDALRrEGKIEFIQVRHEEAAAFAASAEAKLTGKlgvclgssgpgaihllngl 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 548923731 77 --------PLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIyGRPGACYVDIPADF 147
Cdd:cd07039 83 ydakrdraPVLAIAGQVPTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRAIRTAI-AKRGVAVLILPGDV 160
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
346-533 |
7.17e-08 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 53.05 E-value: 7.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 346 LPMNYYTVFYHVQEQLPRD-CFVVSEGANTMdIGRTVLQNYLPRHRLDAGTFGTmgvgLGFAIAAAVVAKDRSPGQWIIC 424
Cdd:cd02006 6 VPIKPQRVYEEMNKAFGRDvRYVTTIGLSQI-AGAQMLHVYKPRHWINCGQAGP----LGWTVPAALGVAAADPDRQVVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 425 VEGDSAFGFSGMEVETICRYNLPIILLVVNNNGI------YQGFDTDtWKEMLKFQDATAvvPPMCLLPNSHYeQVMTAF 498
Cdd:cd02006 81 LSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLglirqaQRAFDMD-YQVNLAFENINS--SELGGYGVDHV-KVAEGL 156
|
170 180 190
....*....|....*....|....*....|....*...
gi 548923731 499 GGKGYFVQTPEELQKSLRQS---LADTTKPSLINIMIE 533
Cdd:cd02006 157 GCKAIRVTKPEELAAAFEQAkklMAEHRVPVVVEAILE 194
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
163-457 |
9.41e-08 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 54.71 E-value: 9.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 163 CMSPPIS--MAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVG---A 237
Cdd:PLN02573 199 FLTPRLSnkMSLEAAVEAAAEFLNKAVKPVLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPHFIGtywG 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 238 ARSRA-----LQFADVIVLFGARLNWILHFGLPPRYQPDvKFIQVDICAEELGNnvKPAvtlLGNIhaVTKQLLEELDKt 312
Cdd:PLN02573 279 AVSTPfcaeiVESADAYLFAGPIFNDYSSVGYSLLLKKE-KAIIVQPDRVTIGN--GPA---FGCV--LMKDFLEALAK- 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 313 pwqyppeskwwktlreKMKSNEAA-----------SKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEganTMDIGRTV 381
Cdd:PLN02573 350 ----------------RVKKNTTAyenykrifvpeGEPLKSEPGEPLRVNVLFKHIQKMLSGDTAVIAE---TGDSWFNC 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 382 LQNYLPR-----HRLDAGTFG-TMGVGLGFAIAAavvakdrsPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 455
Cdd:PLN02573 411 QKLKLPEgcgyeFQMQYGSIGwSVGATLGYAQAA--------PDKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFLINN 482
|
..
gi 548923731 456 NG 457
Cdd:PLN02573 483 GG 484
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
389-534 |
2.64e-05 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 45.37 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 389 HRL-DAGTFGTMGVGLGFA-----IAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGI---- 458
Cdd:cd02003 30 HKLwRARTPGGYHLEYGYScmgyeIAAGLGAKLAKPDREVYVLVGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFgcin 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 459 -------YQGFDTDtwkemLKFQDATAVVPPMCLLPnSHYEQVMTAFGGKGYFVQTPEELQKSLRQSlADTTKPSLINIM 531
Cdd:cd02003 110 nlqestgSGSFGTE-----FRDRDQESGQLDGALLP-VDFAANARSLGARVEKVKTIEELKAALAKA-KASDRTTVIVIK 182
|
...
gi 548923731 532 IEP 534
Cdd:cd02003 183 TDP 185
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
166-532 |
1.18e-04 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 44.84 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 166 PPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEES---------IKKLVEQYklpflPTPM--GKGVVP-DNHPY 233
Cdd:PRK07586 177 PAPAAVDPAAVEAAAAALRSGEPTVLLLGGRALRERGLAAaariaaatgARLLAETF-----PARMerGAGRPAvERLPY 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 234 CVGAARsRALQFADVIVLFGAR--LNWILHFGLPPRYQPDvkfiqvdicaeelGNNVkpaVTLLG---NIHAVTKQLLEE 308
Cdd:PRK07586 252 FAEQAL-AQLAGVRHLVLVGAKapVAFFAYPGKPSRLVPE-------------GCEV---HTLAGpgeDAAAALEALADA 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 309 LDKTPwQYPPeskwwktlrekmksneAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTmdiGR---TVLQNy 385
Cdd:PRK07586 315 LGAKP-AAPP----------------LAAPARPPLPTGALTPEAIAQVIAALLPENAIVVDESITS---GRgffPATAG- 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 386 LPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPIIlLVVNNNGIYQ----- 460
Cdd:PRK07586 374 AAPHDWLTLTGGAIGQGLPLATGAAVACPDRK----VLALQGDGSAMYTIQALWTQARENLDVT-TVIFANRAYAilrge 448
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 548923731 461 ------GFDTDTWKEMLKFQDatavvppmcllPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADtTKPSLINIMI 532
Cdd:PRK07586 449 larvgaGNPGPRALDMLDLDD-----------PDLDWVALAEGMGVPARRVTTAEEFADALAAALAE-PGPHLIEAVV 514
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
18-145 |
3.24e-04 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 41.18 E-value: 3.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 18 KVIAQALKTQDVEYIFGIVGIPVTEI--AIAAQQlGIKYIGMRNEQAACYAASAIG------------------------ 71
Cdd:cd06586 1 AAFAEVLTAWGVRHVFGYPGDEISSLldALREGD-KRIIDTVIHELGAAGAAAGYAraggppvvivtsgtgllnaingla 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 548923731 72 --YLTSRPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSiYGRPGACYVDIPA 145
Cdd:cd06586 80 daAAEHLPVVFLIGARGISAQAKQTFQSMFDLGMYRSIPEANISSPSPAELPAGIDHAIRTA-YASQGPVVVRLPR 154
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
369-532 |
1.01e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 41.78 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 369 SEGANTMDIGRTVLQNYLPRhrldagTFGTMGVGLGFAIAAAVVAKDRSpgqwIICVEGDSAFGFSGMEVETICRYNLPI 448
Cdd:PRK12474 367 SGLFFDMSYDRARPHTHLPL------TGGSIGQGLPLAAGAAVAAPDRK----VVCPQGDGGAAYTMQALWTMARENLDV 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 449 ILLVVNNNGIyqgfdTDTWKEMLKFQDATAVVPPMCLL----PNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADtTK 524
Cdd:PRK12474 437 TVVIFANRSY-----AILNGELQRVGAQGAGRNALSMLdlhnPELNWMKIAEGLGVEASRATTAEEFSAQYAAAMAQ-RG 510
|
....*...
gi 548923731 525 PSLINIMI 532
Cdd:PRK12474 511 PRLIEAMI 518
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
397-530 |
1.03e-03 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 40.27 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 397 GTMGVGLGFAIAAavvakdrspGQWIICVEGDSAF-----GFSGMEVETicrynLPIILLVVNNNG--IyqgFDTdtwKE 469
Cdd:cd02009 55 GTLSTALGIALAT---------DKPTVLLTGDLSFlhdlnGLLLGKQEP-----LNLTIVVINNNGggI---FSL---LP 114
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 548923731 470 MLKFQDATAVVPPMCLlpNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLaDTTKPSLINI 530
Cdd:cd02009 115 QASFEDEFERLFGTPQ--GLDFEHLAKAYGLEYRRVSSLDELEQALESAL-AQDGPHVIEV 172
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
376-456 |
5.17e-03 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 38.03 E-value: 5.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 548923731 376 DIGRTVLQNYLPRHRLDagTFGTMGVGLGFAIAAAVVakdrSPGQWIICVEGDSAFGFSGME--VETIcrYN-LPIILLV 452
Cdd:cd02008 32 DIGCYTLGALPPLNAID--TCTCMGASIGVAIGMAKA----SEDKKVVAVIGDSTFFHSGILglINAV--YNkANITVVI 103
|
....
gi 548923731 453 VNNN 456
Cdd:cd02008 104 LDNR 107
|
|
| |
