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Conserved domains on  [gi|385719204|ref|NP_001245325|]
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coiled-coil domain-containing protein 103 isoform 1 [Homo sapiens]

Protein Classification

Dynein_attach_N and RPAP3_C domain-containing protein( domain architecture ID 11239486)

Dynein_attach_N and RPAP3_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Dynein_attach_N pfam15867
Dynein attachment factor N-terminus; This family represents the N-terminus of a dynein arm ...
 7-74 2.43e-33

Dynein attachment factor N-terminus; This family represents the N-terminus of a dynein arm attachment factor which is required for dynein arm assembly and cilia motility.


:

Pssm-ID: 464912  Cd Length: 68  Bit Score: 115.02  E-value: 2.43e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 385719204    7 INFKALEKELQAALTADEKYKRENAAKLRAVeQRVASYEEFRGIVLASHLKPLERKDKMGGKRT-VPWN 74
Cdd:pfam15867   1 IDFAKLEKELQRALEKDEKYWRENDAKLRAV-QKVASYEEFRDIVLAAHLKPLEKKDKANAKKKnRIWN 68
RPAP3_C pfam13877
Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of ...
 99-188 5.44e-22

Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.


:

Pssm-ID: 464012  Cd Length: 91  Bit Score: 86.57  E-value: 5.44e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385719204   99 PETSADFYRDWRRHLPSGPERYQALLQLGGPRLGCLFQTDVGFGLLGELLVALADHVGP-ADRAAVLGILCSLASTGRFT 177
Cdd:pfam13877   1 PRNAYEFERDWRRLRKSSDRLYLYLKSIPPSNLPKIFKNSLDPDLLGEILKALAEHFIEnEDPALVLEILQGLSKVPRFD 80

                          90
                  ....*....|.
gi 385719204  178 LNLSLLSRAER 188
Cdd:pfam13877  81 LAVMFLSKAEK 91
 
Name Accession Description Interval E-value
Dynein_attach_N pfam15867
Dynein attachment factor N-terminus; This family represents the N-terminus of a dynein arm ...
 7-74 2.43e-33

Dynein attachment factor N-terminus; This family represents the N-terminus of a dynein arm attachment factor which is required for dynein arm assembly and cilia motility.


Pssm-ID: 464912  Cd Length: 68  Bit Score: 115.02  E-value: 2.43e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 385719204    7 INFKALEKELQAALTADEKYKRENAAKLRAVeQRVASYEEFRGIVLASHLKPLERKDKMGGKRT-VPWN 74
Cdd:pfam15867   1 IDFAKLEKELQRALEKDEKYWRENDAKLRAV-QKVASYEEFRDIVLAAHLKPLEKKDKANAKKKnRIWN 68
RPAP3_C pfam13877
Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of ...
 99-188 5.44e-22

Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.


Pssm-ID: 464012  Cd Length: 91  Bit Score: 86.57  E-value: 5.44e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385719204   99 PETSADFYRDWRRHLPSGPERYQALLQLGGPRLGCLFQTDVGFGLLGELLVALADHVGP-ADRAAVLGILCSLASTGRFT 177
Cdd:pfam13877   1 PRNAYEFERDWRRLRKSSDRLYLYLKSIPPSNLPKIFKNSLDPDLLGEILKALAEHFIEnEDPALVLEILQGLSKVPRFD 80

                          90
                  ....*....|.
gi 385719204  178 LNLSLLSRAER 188
Cdd:pfam13877  81 LAVMFLSKAEK 91
 
Name Accession Description Interval E-value
Dynein_attach_N pfam15867
Dynein attachment factor N-terminus; This family represents the N-terminus of a dynein arm ...
 7-74 2.43e-33

Dynein attachment factor N-terminus; This family represents the N-terminus of a dynein arm attachment factor which is required for dynein arm assembly and cilia motility.


Pssm-ID: 464912  Cd Length: 68  Bit Score: 115.02  E-value: 2.43e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 385719204    7 INFKALEKELQAALTADEKYKRENAAKLRAVeQRVASYEEFRGIVLASHLKPLERKDKMGGKRT-VPWN 74
Cdd:pfam15867   1 IDFAKLEKELQRALEKDEKYWRENDAKLRAV-QKVASYEEFRDIVLAAHLKPLEKKDKANAKKKnRIWN 68
RPAP3_C pfam13877
Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of ...
 99-188 5.44e-22

Potential Monad-binding region of RPAP3; This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.


Pssm-ID: 464012  Cd Length: 91  Bit Score: 86.57  E-value: 5.44e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 385719204   99 PETSADFYRDWRRHLPSGPERYQALLQLGGPRLGCLFQTDVGFGLLGELLVALADHVGP-ADRAAVLGILCSLASTGRFT 177
Cdd:pfam13877   1 PRNAYEFERDWRRLRKSSDRLYLYLKSIPPSNLPKIFKNSLDPDLLGEILKALAEHFIEnEDPALVLEILQGLSKVPRFD 80

                          90
                  ....*....|.
gi 385719204  178 LNLSLLSRAER 188
Cdd:pfam13877  81 LAVMFLSKAEK 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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