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Conserved domains on  [gi|324120958|ref|NP_001191215|]
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mucin-1 isoform 10 precursor [Homo sapiens]

Protein Classification

SEA domain-containing protein( domain architecture ID 10640846)

SEA domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 263-381 2.04e-42

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


:

Pssm-ID: 214554  Cd Length: 121  Bit Score: 146.79  E-value: 2.04e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   263 PQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQG----GFLGLSNIKFRPGSVVVQLTLAFRE 338
Cdd:smart00200   1 PTQSFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKLLEQIYGKTdlkpDFVGTEVIEFRNGSVVVDLGLLFNE 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 324120958   339 GTINVHDVETQFNQYKTEAAsrYNLTISDVSVSDVPFPFSAQS 381
Cdd:smart00200  81 GVTNGQDVEEDLLQVIKQAA--YSLKITNVNVVDVLDPDSADS 121
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 88-184 7.58e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   88 TLAPATEPASGSAATwgqDVTSVPVTRPALGSTtPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGV 167
Cdd:PHA03247 2736 PAAPAPPAVPAGPAT---PGGPARPARPPTTAG-PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV 2811

                          90
                  ....*....|....*..
gi 324120958  168 TSAPDNRPALGSTAPPV 184
Cdd:PHA03247 2812 LAPAAALPPAASPAGPL 2828
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 26-267 2.11e-04

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   26 PATVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPaTEPASGSAATWGQ 105
Cdd:PHA03307   94 TLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASP-AAVASDAASSRQA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  106 DVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPG-STAPPAHGVTSAPDNRPALGSTAPPv 184
Cdd:PHA03307  173 ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGrSAADDAGASSSDSSSSESSGCGWGP- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  185 HNVTSASGSASGSASTLV---HNGTSARATTTPASKSTPFSIPS-----HHSDTPTTLASHSTKTDASSTHHSTVPPLTS 256
Cdd:PHA03307  252 ENECPLPRPAPITLPTRIweaSGWNGPSSRPGPASSSSSPRERSpspspSSPGSGPAPSSPRASSSSSSSRESSSSSTSS 331

                         250
                  ....*....|.
gi 324120958  257 SNHSTSPQLST 267
Cdd:PHA03307  332 SSESSRGAAVS 342
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 263-381 2.04e-42

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 146.79  E-value: 2.04e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   263 PQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQG----GFLGLSNIKFRPGSVVVQLTLAFRE 338
Cdd:smart00200   1 PTQSFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKLLEQIYGKTdlkpDFVGTEVIEFRNGSVVVDLGLLFNE 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 324120958   339 GTINVHDVETQFNQYKTEAAsrYNLTISDVSVSDVPFPFSAQS 381
Cdd:smart00200  81 GVTNGQDVEEDLLQVIKQAA--YSLKITNVNVVDVLDPDSADS 121
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 271-337 1.31e-10

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 58.02  E-value: 1.31e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 324120958  271 FFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQ----GGFLGLSNIKFRP--GSVVVQLTLAFR 337
Cdd:pfam01390   2 YYTGSFKITNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNsslrKQYIKSHVLRLRPdgGSVVVDVVLVFR 74
PHA03247 PHA03247
large tegument protein UL36; Provisional
 88-184 7.58e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   88 TLAPATEPASGSAATwgqDVTSVPVTRPALGSTtPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGV 167
Cdd:PHA03247 2736 PAAPAPPAVPAGPAT---PGGPARPARPPTTAG-PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV 2811

                          90
                  ....*....|....*..
gi 324120958  168 TSAPDNRPALGSTAPPV 184
Cdd:PHA03247 2812 LAPAAALPPAASPAGPL 2828
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 99-269 1.38e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.52  E-value: 1.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   99 SAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPD-NRPAL 177
Cdd:pfam05109 460 APASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNaTSPTL 539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  178 GSTAPpvhnvtsasgsaSGSASTLVHNGTSAR-ATTTPASKSTpfsIPSHHSDTPTTLASHSTKTDASSTHHSTVPPLTS 256
Cdd:pfam05109 540 GKTSP------------TSAVTTPTPNATSPTpAVTTPTPNAT---IPTLGKTSPTSAVTTPTPNATSPTVGETSPQANT 604

                         170
                  ....*....|...
gi 324120958  257 SNHSTSPQLSTGV 269
Cdd:pfam05109 605 TNHTLGGTSSTPV 617
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 26-267 2.11e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   26 PATVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPaTEPASGSAATWGQ 105
Cdd:PHA03307   94 TLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASP-AAVASDAASSRQA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  106 DVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPG-STAPPAHGVTSAPDNRPALGSTAPPv 184
Cdd:PHA03307  173 ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGrSAADDAGASSSDSSSSESSGCGWGP- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  185 HNVTSASGSASGSASTLV---HNGTSARATTTPASKSTPFSIPS-----HHSDTPTTLASHSTKTDASSTHHSTVPPLTS 256
Cdd:PHA03307  252 ENECPLPRPAPITLPTRIweaSGWNGPSSRPGPASSSSSPRERSpspspSSPGSGPAPSSPRASSSSSSSRESSSSSTSS 331

                         250
                  ....*....|.
gi 324120958  257 SNHSTSPQLST 267
Cdd:PHA03307  332 SSESSRGAAVS 342
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 24-267 1.31e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   24 PKPATVVTGS--GHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAA 101
Cdd:pfam17823  67 PAPVTLTKGTsaAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAPR 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  102 TWGQDVTSVPVTRPALGSTTPPaHDVTSAPDNKPAPGSTAPPAHGVTSAPDT--RPAPGSTAPPAHGVTSAPDN-RPALG 178
Cdd:pfam17823 147 AAACRANASAAPRAAIAAASAP-HAASPAPRTAASSTTAASSTTAASSAPTTaaSSAPATLTPARGISTAATATgHPAAG 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  179 STAPPVHNVTSASGSASGSASTLVHN--GTSARATTTPASKSTPFSIPSHHSDTPTtlASHSTKTDASSthHSTVPPLTS 256
Cdd:pfam17823 226 TALAAVGNSSPAAGTVTAAVGTVTPAalATLAAAAGTVASAAGTINMGDPHARRLS--PAKHMPSDTMA--RNPAAPMGA 301

                         250
                  ....*....|.
gi 324120958  257 SNHSTSPQLST 267
Cdd:pfam17823 302 QAQGPIIQVST 312
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
67-259 5.74e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 39.35  E-value: 5.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  67 SSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHG 146
Cdd:COG3469   20 VTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVAT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958 147 VTSAPD---TRPAPGSTAPPAHGVTSAPDNRPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSI 223
Cdd:COG3469  100 STASGAntgTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTP 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 324120958 224 PSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNH 259
Cdd:COG3469  180 SATTTATATTASGATTPSATTTATTTGPPTPGLPKH 215
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 263-381 2.04e-42

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 146.79  E-value: 2.04e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   263 PQLSTGVSFFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQG----GFLGLSNIKFRPGSVVVQLTLAFRE 338
Cdd:smart00200   1 PTQSFGVSLSVLSVEGENLQYSPSLEDPSSEEYQELVRDVEKLLEQIYGKTdlkpDFVGTEVIEFRNGSVVVDLGLLFNE 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 324120958   339 GTINVHDVETQFNQYKTEAAsrYNLTISDVSVSDVPFPFSAQS 381
Cdd:smart00200  81 GVTNGQDVEEDLLQVIKQAA--YSLKITNVNVVDVLDPDSADS 121
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 271-337 1.31e-10

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 58.02  E-value: 1.31e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 324120958  271 FFFLSFHISNLQFNSSLEDPSTDYYQELQRDISEMFLQIYKQ----GGFLGLSNIKFRP--GSVVVQLTLAFR 337
Cdd:pfam01390   2 YYTGSFKITNLQYTPDLGNPSSQEFKSLSRRIESLLNELFRNsslrKQYIKSHVLRLRPdgGSVVVDVVLVFR 74
PHA03247 PHA03247
large tegument protein UL36; Provisional
 88-184 7.58e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   88 TLAPATEPASGSAATwgqDVTSVPVTRPALGSTtPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGV 167
Cdd:PHA03247 2736 PAAPAPPAVPAGPAT---PGGPARPARPPTTAG-PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV 2811

                          90
                  ....*....|....*..
gi 324120958  168 TSAPDNRPALGSTAPPV 184
Cdd:PHA03247 2812 LAPAAALPPAASPAGPL 2828
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 99-269 1.38e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.52  E-value: 1.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   99 SAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPD-NRPAL 177
Cdd:pfam05109 460 APASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNaTSPTL 539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  178 GSTAPpvhnvtsasgsaSGSASTLVHNGTSAR-ATTTPASKSTpfsIPSHHSDTPTTLASHSTKTDASSTHHSTVPPLTS 256
Cdd:pfam05109 540 GKTSP------------TSAVTTPTPNATSPTpAVTTPTPNAT---IPTLGKTSPTSAVTTPTPNATSPTVGETSPQANT 604

                         170
                  ....*....|...
gi 324120958  257 SNHSTSPQLSTGV 269
Cdd:pfam05109 605 TNHTLGGTSSTPV 617
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 90-188 1.61e-04

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 44.31  E-value: 1.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  90 APATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDN--KPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGV 167
Cdd:PLN02217 567 GSTNSTPTGSAASSNTTFSSDSPSTVVAPSTSPPAGHLGSPPATpsKIVSPSTSPPASHLGSPSTTPSSPESSIKVASTE 646

                         90       100
                 ....*....|....*....|.
gi 324120958 168 TSAPDNRPALGSTAPPVHNVT 188
Cdd:PLN02217 647 TASPESSIKVASTESSVSMVS 667
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 26-267 2.11e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   26 PATVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPaTEPASGSAATWGQ 105
Cdd:PHA03307   94 TLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASP-AAVASDAASSRQA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  106 DVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPG-STAPPAHGVTSAPDNRPALGSTAPPv 184
Cdd:PHA03307  173 ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGrSAADDAGASSSDSSSSESSGCGWGP- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  185 HNVTSASGSASGSASTLV---HNGTSARATTTPASKSTPFSIPS-----HHSDTPTTLASHSTKTDASSTHHSTVPPLTS 256
Cdd:PHA03307  252 ENECPLPRPAPITLPTRIweaSGWNGPSSRPGPASSSSSPRERSpspspSSPGSGPAPSSPRASSSSSSSRESSSSSTSS 331

                         250
                  ....*....|.
gi 324120958  257 SNHSTSPQLST 267
Cdd:PHA03307  332 SSESSRGAAVS 342
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2-233 4.41e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 4.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958    2 TPGTQSPFFLLLLLTVLTATTAPKPATVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSST 81
Cdd:PHA03247 2600 APVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP 2679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   82 TQG-QDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSA----PDTRPA 156
Cdd:PHA03247 2680 PQRpRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAtpggPARPAR 2759

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 324120958  157 PGSTA-PPAHGVTSAPDNRPALGSTAPPVHNVTSASGSASGSASTLVHngtsARATTTPASKSTPFSIPSHHSDTPTT 233
Cdd:PHA03247 2760 PPTTAgPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP----PAAVLAPAAALPPAASPAGPLPPPTS 2833
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2-224 5.65e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 5.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958    2 TPGTQSPFFLLLLLTVLTATTAPKPATvvtgsgHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSST 81
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVP------AGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLS 2792

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   82 TQGQDVTLAPAtePASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTA 161
Cdd:PHA03247 2793 ESRESLPSPWD--PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRS 2870

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 324120958  162 PPAhgVTSAPDNRPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIP 224
Cdd:PHA03247 2871 PAA--KPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 95-270 6.55e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.47  E-value: 6.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   95 PASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAhgvTSAPDNR 174
Cdd:PHA03307   55 VVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPA---SPPPSPA 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  175 PALGSTAPPVHNVTSASGSASGSAStlVHNGTSARATTTPASKSTPFSIPSHHSDTPTTlASHSTKTDASSTHHSTVPPL 254
Cdd:PHA03307  132 PDLSEMLRPVGSPGPPPAASPPAAG--ASPAAVASDAASSRQAALPLSSPEETARAPSS-PPAEPPPSTPPAAASPRPPR 208

                         170
                  ....*....|....*.
gi 324120958  255 TSSNHSTSPQLSTGVS 270
Cdd:PHA03307  209 RSSPISASASSPAPAP 224
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 24-267 1.31e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.10  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958   24 PKPATVVTGS--GHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAA 101
Cdd:pfam17823  67 PAPVTLTKGTsaAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAPR 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  102 TWGQDVTSVPVTRPALGSTTPPaHDVTSAPDNKPAPGSTAPPAHGVTSAPDT--RPAPGSTAPPAHGVTSAPDN-RPALG 178
Cdd:pfam17823 147 AAACRANASAAPRAAIAAASAP-HAASPAPRTAASSTTAASSTTAASSAPTTaaSSAPATLTPARGISTAATATgHPAAG 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  179 STAPPVHNVTSASGSASGSASTLVHN--GTSARATTTPASKSTPFSIPSHHSDTPTtlASHSTKTDASSthHSTVPPLTS 256
Cdd:pfam17823 226 TALAAVGNSSPAAGTVTAAVGTVTPAalATLAAAAGTVASAAGTINMGDPHARRLS--PAKHMPSDTMA--RNPAAPMGA 301

                         250
                  ....*....|.
gi 324120958  257 SNHSTSPQLST 267
Cdd:pfam17823 302 QAQGPIIQVST 312
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 101-184 1.87e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 41.03  E-value: 1.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  101 ATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAhgvtSAPDTRPAPGSTAPPAHGVTSAPDNRPALGST 180
Cdd:PRK12270   34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAA----AAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPA 109


                  ....
gi 324120958  181 APPV 184
Cdd:PRK12270  110 AAAV 113
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 90-184 3.97e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 3.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  90 APATEPASGSAATwgqDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTA---PPAHGVTSAPDTRPAPGSTAPPAHG 166
Cdd:PRK14951 396 QAAAAPAPAAAPA---AAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAvalAPAPPAQAAPETVAIPVRVAPEPAV 472

                         90
                 ....*....|....*...
gi 324120958 167 VTSAPDnrPALGSTAPPV 184
Cdd:PRK14951 473 ASAAPA--PAAAPAAARL 488
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
95-238 4.04e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 4.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  95 PASGSAATwgqDVTSVPVTRPALGSTTPPAhdvtSAPDNKPAPGSTAPPAHGVTSAPDTR-PAPGSTAPPAHGVTSAPDN 173
Cdd:PRK12323 374 PATAAAAP---VAQPAPAAAAPAAAAPAPA----APPAAPAAAPAAAAAARAVAAAPARRsPAPEALAAARQASARGPGG 446

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 324120958 174 RPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPShHSDTPTTLASHS 238
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP-WEELPPEFASPA 510
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
92-253 4.28e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.83  E-value: 4.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  92 ATEPA-SGSAATWGQDVTSVPVTRPALGSTTPPAhdvtsapdnkpAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSA 170
Cdd:PRK07003 357 AFEPAvTGGGAPGGGVPARVAGAVPAPGARAAAA-----------VGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEA 425

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958 171 PDNRPALGSTAPPVHNVTSASGSASGSASTLVH-NGTSARATTTPASKSTPFSIPShhSDTPTTLASHSTKTDASSTHHS 249
Cdd:PRK07003 426 PPAAPAPPATADRGDDAADGDAPVPAKANARASaDSRCDERDAQPPADSGSASAPA--SDAPPDAAFEPAPRAAAPSAAT 503


                 ....
gi 324120958 250 TVPP 253
Cdd:PRK07003 504 PAAV 507
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
87-182 4.52e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.47  E-value: 4.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  87 VTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVT-SAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAH 165
Cdd:PRK12323 395 AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAArQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAA 474

                         90
                 ....*....|....*..
gi 324120958 166 GVTSAPDNRPALGSTAP 182
Cdd:PRK12323 475 AAAAAPARAAPAAAPAP 491
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
90-175 5.01e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.47  E-value: 5.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  90 APATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGsTAPPAHGVTSAPDTRPAPGSTAPPAHGVTS 169
Cdd:PRK12323 413 AAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAA-ARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491


                 ....*.
gi 324120958 170 APDNRP 175
Cdd:PRK12323 492 ADDDPP 497
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 85-188 5.21e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 39.46  E-value: 5.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  85 QDVTLAPATEPASGSAATWGQdVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPpa 164
Cdd:PRK07994 362 AAPLPEPEVPPQSAAPAASAQ-ATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKA-- 438

                         90       100
                 ....*....|....*....|....
gi 324120958 165 hgvtsaPDNRPALGSTAPPVHNVT 188
Cdd:PRK07994 439 ------KKSEPAAASRARPVNSAL 456
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
67-259 5.74e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 39.35  E-value: 5.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  67 SSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHG 146
Cdd:COG3469   20 VTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVAT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958 147 VTSAPD---TRPAPGSTAPPAHGVTSAPDNRPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSI 223
Cdd:COG3469  100 STASGAntgTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTP 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 324120958 224 PSHHSDTPTTLASHSTKTDASSTHHSTVPPLTSSNH 259
Cdd:COG3469  180 SATTTATATTASGATTPSATTTATTTGPPTPGLPKH 215
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 86-183 5.94e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.02  E-value: 5.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  86 DVTLAPATEPASGSAAtwgqdVTSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAhGVTSAPDTRPAPGS--TAPP 163
Cdd:PRK14950 357 EALLVPVPAPQPAKPT-----AAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPP-PVPPRPVAPPVPHTpeSAPK 430

                         90       100
                 ....*....|....*....|
gi 324120958 164 AHGVTSAPDNRPALGSTAPP 183
Cdd:PRK14950 431 LTRAAIPVDEKPKYTPPAPP 450
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 81-174 6.17e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 39.06  E-value: 6.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  81 TTQGQDVTLAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKP-------APGSTAPPAHGVTSAPDT 153
Cdd:COG3266  272 LGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKpvvtetaAPAAPAPEAAAAAAAPAA 351

                         90       100
                 ....*....|....*....|.
gi 324120958 154 RPAPGSTAPPAHGVTSAPDNR 174
Cdd:COG3266  352 PAVAKKLAADEQWLASQPASH 372
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
89-162 8.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 38.60  E-value: 8.34e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 324120958  89 LAPATEPASGSAATWGQDVTSVPVTRPALGSTTPPAHDVTSAPDNKPA-----PGSTAPPAHGVTSAPDTRPAPGSTAP 162
Cdd:PRK14971 386 PAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAavpvnPPSTAPQAVRPAQFKEEKKIPVSKVS 464
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 28-184 8.50e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 38.81  E-value: 8.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 324120958  28 TVVTGSGHASSTPGGEKETSATQRSSVPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDV 107
Cdd:PRK07764 583 QVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDA 662

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 324120958 108 TSVPVTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSAPDNRPALGSTAPPV 184
Cdd:PRK07764 663 SDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPV 739
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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