NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|312222777|ref|NP_001185923|]
View 

NAD kinase isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
pnk super family cl28462
bifunctional NADP phosphatase/NAD kinase;
200-578 1.14e-86

bifunctional NADP phosphatase/NAD kinase;


The actual alignment was detected with superfamily member PLN02727:

Pssm-ID: 333282 [Multi-domain]  Cd Length: 986  Bit Score: 289.48  E-value: 1.14e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 200 QRLTWNKSPKSVLVIKKMRDAsllqpfkelcthLMEArgaggkgawgahgvggasihitAPRVGSAggmsrlaLCFQENM 279
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE------------LMEE----------------------AKEVASF-------LYHQEKM 708

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 280 IVYVEKKVLEdpAIASDESFGAVKkkfcTF-REDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLT 358
Cdd:PLN02727 709 NVLVEPDVHD--IFARIPGFGFVQ----TFySQDTSDLHERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLT 782

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 359 PFSFENFQSQVTQVIEGNAA-----VVLRSRLKVRVVKelrgkktavhnglgeNGSQAAGLDMDVgkqamqyqvLNEVVI 433
Cdd:PLN02727 783 SHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR---------------NGKAMPGKVFDV---------LNEVVV 838

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 434 DRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVP--AGVEL 511
Cdd:PLN02727 839 DRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLEL 918

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 312222777 512 KImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQ 578
Cdd:PLN02727 919 KI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTGDWFRSLIRCLNWNERLDQ 983
 
Name Accession Description Interval E-value
PLN02727 PLN02727
NAD kinase
 200-578 1.14e-86

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 289.48  E-value: 1.14e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 200 QRLTWNKSPKSVLVIKKMRDAsllqpfkelcthLMEArgaggkgawgahgvggasihitAPRVGSAggmsrlaLCFQENM 279
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE------------LMEE----------------------AKEVASF-------LYHQEKM 708

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 280 IVYVEKKVLEdpAIASDESFGAVKkkfcTF-REDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLT 358
Cdd:PLN02727 709 NVLVEPDVHD--IFARIPGFGFVQ----TFySQDTSDLHERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLT 782

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 359 PFSFENFQSQVTQVIEGNAA-----VVLRSRLKVRVVKelrgkktavhnglgeNGSQAAGLDMDVgkqamqyqvLNEVVI 433
Cdd:PLN02727 783 SHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR---------------NGKAMPGKVFDV---------LNEVVV 838

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 434 DRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVP--AGVEL 511
Cdd:PLN02727 839 DRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLEL 918

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 312222777 512 KImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQ 578
Cdd:PLN02727 919 KI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTGDWFRSLIRCLNWNERLDQ 983
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
312-575 6.50e-56

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 189.96  E-value: 6.50e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 312 DYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVK 391
Cdd:COG0061   45 PLEELGEEADLVIVLGGDGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDR 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 392 ElrgkktavhnglgengsqaagldmdvGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTgsta 471
Cdd:COG0061  125 D--------------------------GEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgsta 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 472 yaaaagasMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTSCYPLp 551
Cdd:COG0061  179 ynlsaggpIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRP-AVLVADGQEVRDLEPGDRVEIRRSPKPV- 256

                        250       260
                 ....*....|....*....|....
gi 312222777 552 SIcVRDPVSDWFESLAQCLHWNVR 575
Cdd:COG0061  257 RL-LRLKDHSFFERLREKLGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 428-553 6.31e-31

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 117.02  E-value: 6.31e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777  428 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPA 507
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 312222777  508 GVELKIMlsPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSI 553
Cdd:pfam20143  81 SSKLRIR--VLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
 
Name Accession Description Interval E-value
PLN02727 PLN02727
NAD kinase
 200-578 1.14e-86

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 289.48  E-value: 1.14e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 200 QRLTWNKSPKSVLVIKKMRDAsllqpfkelcthLMEArgaggkgawgahgvggasihitAPRVGSAggmsrlaLCFQENM 279
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE------------LMEE----------------------AKEVASF-------LYHQEKM 708

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 280 IVYVEKKVLEdpAIASDESFGAVKkkfcTF-REDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLT 358
Cdd:PLN02727 709 NVLVEPDVHD--IFARIPGFGFVQ----TFySQDTSDLHERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLT 782

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 359 PFSFENFQSQVTQVIEGNAA-----VVLRSRLKVRVVKelrgkktavhnglgeNGSQAAGLDMDVgkqamqyqvLNEVVI 433
Cdd:PLN02727 783 SHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR---------------NGKAMPGKVFDV---------LNEVVV 838

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 434 DRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVP--AGVEL 511
Cdd:PLN02727 839 DRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPdsARLEL 918

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 312222777 512 KImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQ 578
Cdd:PLN02727 919 KI--PDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTGDWFRSLIRCLNWNERLDQ 983
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 202-578 1.41e-80

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 262.46  E-value: 1.41e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 202 LTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEargaggkgawgahgvggasihitaprvgsaggmsrlalcfQENMIV 281
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLRE----------------------------------------QKGLNI 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 282 YVEKKVLEDpAIASDESFGAVKKkfCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFS 361
Cdd:PLN02935 228 YVEPRVKKE-LLSESSYFNFVQT--WEDEKEILLLHTKVDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFH 304

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 362 FENFQSQVTQVIEGNAAVVLRSRLKVRVVKElrgkktAVHNGLGENGSqaagldmdvgkqamqYQVLNEVVIDRGPSSYL 441
Cdd:PLN02935 305 SEQYRDCLDAILKGPISITLRHRLQCHIIRD------AAKNEYETEEP---------------ILVLNEVTIDRGISSFL 363

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 442 SNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARN 521
Cdd:PLN02935 364 TNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRG 443

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 312222777 522 TAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQ 578
Cdd:PLN02935 444 QAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVESTNDFLRSIHDGLHWNLRKTQ 500
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
312-575 6.50e-56

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 189.96  E-value: 6.50e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 312 DYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVK 391
Cdd:COG0061   45 PLEELGEEADLVIVLGGDGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDR 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 392 ElrgkktavhnglgengsqaagldmdvGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTgsta 471
Cdd:COG0061  125 D--------------------------GEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgsta 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 472 yaaaagasMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSISITTSCYPLp 551
Cdd:COG0061  179 ynlsaggpIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRP-AVLVADGQEVRDLEPGDRVEIRRSPKPV- 256

                        250       260
                 ....*....|....*....|....
gi 312222777 552 SIcVRDPVSDWFESLAQCLHWNVR 575
Cdd:COG0061  257 RL-LRLKDHSFFERLREKLGWGGD 279
ppnK PRK01231
NAD(+) kinase;
321-575 4.55e-36

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 136.63  E-value: 4.55e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 321 DFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVrvvkELRGKKTAV 400
Cdd:PRK01231  64 DLVIVVGGDGSLLGAARALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEA----EVRRGGEVI 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 401 HNGLGengsqaagldmdvgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASM 480
Cdd:PRK01231 140 GQGDA----------------------LNDVVLHPGKSTRMIEFELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPI 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 481 IHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDpvS 560
Cdd:PRK01231 198 MHPKLDAIVLVPMFPHTLSSRPIVVDGNSEIKIVISKDNRTYPRVSCDGQNSVTLAPGDTVTIRKKPQKLRLIHPLD--Y 275

                        250
                 ....*....|....*
gi 312222777 561 DWFESLAQCLHWNVR 575
Cdd:PRK01231 276 NYYETCRTKLGWGSR 290
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
272-546 3.12e-35

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 139.86  E-value: 3.12e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 272 ALCFQENMIVYVEKKVLE---DPAIASdesfgAVKKKFCTFREDYDDISNqIDFIICLGGDGTLLYASSLFQGSVPPVMA 348
Cdd:PRK14076 304 AINLALKIIKYLDSKGIPyelESFLYN-----KLKNRLNEECNLIDDIEE-ISHIISIGGDGTVLRASKLVNGEEIPIIC 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 349 FHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKelrgkktavhnglgengsqaagldmdVGKQAMQYQVL 428
Cdd:PRK14076 378 INMGTVGFLTEFSKEEIFKAIDSIISGEYEIEKRTKLSGFILK--------------------------DGHQNILPSAL 431

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 429 NEVVI-DRGPSSYLsNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPA 507
Cdd:PRK14076 432 NEVVItTKNPAKML-HFEVYVNGELVEEVRADGIIISTPTGSTAYSLSAGGPIVEPTVDGFIIVPICPFKLSSRPLVVSA 510

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 312222777 508 GVELKIMLSpeaRNTAWVSFDGRKRQEIRHGDSISITTS 546
Cdd:PRK14076 511 NSEIKIKLL---KKSALVVIDGSIEFEAKKGDEIIFRKS 546
ppnK PRK02155
NAD kinase;
312-573 1.80e-31

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 123.90  E-value: 1.80e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 312 DYDDISNQIDFIICLGGDGTLL-YASSLFQGSVPPVMAFHlGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVV 390
Cdd:PRK02155  56 TPEEIGARADLAVVLGGDGTMLgIGRQLAPYGVPLIGINH-GRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVV 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 391 KElrgkktavhnglgengsqaagldmdvGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGST 470
Cdd:PRK02155 135 RD--------------------------GEPIFHALAFNDVVVNRSGFSGMVELRVSVDGRFMYNQRSDGLIVATPTGST 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 471 AYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSpEARNTAwVSFDGRKRQEIRHGDSISITTSCYpl 550
Cdd:PRK02155 189 AYALSAGGPILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQIV-GGRDVS-VNFDMQSLTSLELGDRIEVRRSPH-- 264

                        250       260
                 ....*....|....*....|....
gi 312222777 551 pSICVRDPVS-DWFESLAQCLHWN 573
Cdd:PRK02155 265 -TVRFLHPVGySYYATLRKKLHWN 287
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 428-553 6.31e-31

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 117.02  E-value: 6.31e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777  428 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPA 507
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 312222777  508 GVELKIMlsPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSI 553
Cdd:pfam20143  81 SSKLRIR--VLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 276-575 2.45e-28

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 114.95  E-value: 2.45e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 276 QENMIVYVEKKVLEDPAIASDESFGavkkkfCTFReDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLG 355
Cdd:PRK04539  32 QHGFTVYLDEVGIKEGCIYTQDTVG------CHIV-NKTELGQYCDLVAVLGGDGTFLSVAREIAPRAVPIIGINQGHLG 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 356 FLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKElrgkktavhnglgengsqaagldmdvGKQAMQYQVLNEVVIDR 435
Cdd:PRK04539 105 FLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIRE--------------------------GKTAERALALNDAVLSR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 436 GPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIML 515
Cdd:PRK04539 159 GGAGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILV 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 312222777 516 SP--EARntawVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDpvSDWFESLAQCLHWNVR 575
Cdd:PRK04539 239 TQggDAR----VHFDGQTHIDVQNLDRITIRRYRNPLRILHPTD--YQYFKTLRQKLHWGEQ 294
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 276-530 5.87e-28

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 113.87  E-value: 5.87e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 276 QENMIVYVEKKVLEdpAIASDESFgavKKKFCTFrEDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLG 355
Cdd:PRK01911  27 ERGAEVLIEEKFLD--FLKQDLKF---HPSYDTF-SDNEELDGSADMVISIGGDGTFLRTATYVGNSNIPILGINTGRLG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 356 FLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKELRGkktavhnglgenGSQAAgldmdvgkqamqyqvLNEVVIDR 435
Cdd:PRK01911 101 FLATVSKEEIEETIDELLNGDYTIEERSLLQLESNPKLFG------------ELNFA---------------LNEIAILK 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 436 GPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVElkIML 515
Cdd:PRK01911 154 RDTSSMITVHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPDDTE--ITL 231

                        250
                 ....*....|....*.
gi 312222777 516 SPEARNTAW-VSFDGR 530
Cdd:PRK01911 232 EVESRSDNFlVSLDSR 247
ppnK PRK01185
NAD(+) kinase;
321-546 1.18e-27

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 112.21  E-value: 1.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 321 DFIICLGGDGTLLYASSLFQGsvpPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVvkelrgkktav 400
Cdd:PRK01185  54 DVIITIGGDGTILRTLQRAKG---PILGINMGGLGFLTEIEIDEVGSAIKKLIRGEYFIDERMKLKVYI----------- 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 401 hnglgeNGSQAagldmdvgkqamqYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASM 480
Cdd:PRK01185 120 ------NGERL-------------EDCTNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSSSAGGPI 180

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 312222777 481 IHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTawVSFDGRKRQEIRHGDSISITTS 546
Cdd:PRK01185 181 LLPNLEGMVISYIAPYSSRPKSVVVPSESTVEIKIAGDQSSL--LILDGQYEYKISKGDTVEISKS 244
ppnK PRK03708
NAD(+) kinase;
304-546 1.19e-26

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 109.80  E-value: 1.19e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 304 KKFCTFRE-DYDDISN-QIDFIICLGGDGTLLYASSLFQGSVpPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVvl 381
Cdd:PRK03708  40 EHLPEFSEeDVLPLEEmDVDFIIAIGGDGTILRIEHKTKKDI-PILGINMGTLGFLTEVEPEETFFALSRLLEGDYFI-- 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 382 RSRLKVRVvkelrgkktaVHNglGENGSQAagldmdvgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGV 461
Cdd:PRK03708 117 DERIKLRV----------YIN--GENVPDA----------------LNEVVILTGIPGKIIHLKYYVDGELADEVRADGL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 462 IVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNtAWVSFDGRKRQEIRHGDSI 541
Cdd:PRK03708 169 IISTPTGSTAYAMSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSRIDVKLLRTGRE-IILVIDGQYYEELPPDTEI 247


                 ....*
gi 312222777 542 SITTS 546
Cdd:PRK03708 248 TIKKS 252
ppnK PRK02645
NAD(+) kinase;
317-572 3.93e-24

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 103.07  E-value: 3.93e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 317 SNQIDFIICLGGDGTLLYAS-SLFQGSVPpVMAFHLG-SLGFLT-PFSFENFQSQVTQVIEGNAAVVLRSRLKVRVvkeL 393
Cdd:PRK02645  55 SELIDLAIVLGGDGTVLAAArHLAPHDIP-ILSVNVGgHLGFLThPRDLLQDESVWDRLQEDRYAIERRMMLQARV---F 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 394 RGKKTavhnglgengsqaagldmDVGKQAMQYQVLNE-----VVIDRGPSSYLsnvDVYLDGHLITTVQGDGVIVSTPTG 468
Cdd:PRK02645 131 EGDRS------------------NEEPVSESYYALNDfylkpASEDRSPTCIL---ELEIDGEVVDQYQGDGLIVSTPTG 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 469 STAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAG--VELKIMLSPEARNTAWVsfDGRKRQEIRHGDSISITTS 546
Cdd:PRK02645 190 STAYTMAAGGPILHPGIDAIIVTPICPMSLSSRPIVIPPGsrVVIWPLGDYDLNIKLWK--DGVLATSIWPGQRCVIQKA 267

                        250       260
                 ....*....|....*....|....*.
gi 312222777 547 CYPLPSICVRDPVSdWFESLAQCLHW 572
Cdd:PRK02645 268 RHPAKFIILEESYS-YYRTLREKLHW 292
pnk PRK14077
NAD(+) kinase;
314-572 5.21e-24

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 102.17  E-value: 5.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 314 DDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKEl 393
Cdd:PRK14077  59 DELFKISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEIEKPYMLSVFLEKK- 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 394 RGKktavhnglgengsqaagldmdvgkqAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 473
Cdd:PRK14077 138 QGK-------------------------ILEKLAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGDGVIVATPAGSTAYN 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 474 AAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMlspeARNTAWVSFDGRKRQEIRHGDSISITTScyPLPSI 553
Cdd:PRK14077 193 MSANGPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEFK----TKSDCILCIDGQDRYKMNDFKSIKVGLS--DKNVA 266

                        250
                 ....*....|....*....
gi 312222777 554 CVRDPVSDWFESLAQCLHW 572
Cdd:PRK14077 267 LIRHKNRDYFQILKEKLHW 285
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 315-550 3.35e-22

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 96.93  E-value: 3.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 315 DISNQIDFIICLGGDGTLLYAS---SLFQGSVPPVmafHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVK 391
Cdd:PRK03378  59 EIGQQADLAIVVGGDGNMLGAArvlARYDIKVIGI---NRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCR 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 392 elrgkktavHNGLGENGSqaagldmdvgkqamqyqVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTA 471
Cdd:PRK03378 136 ---------HGQQKRIST-----------------AINEVVLHPGKVAHMIEFEVYIDDNFAFSQRSDGLIISTPTGSTA 189

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 312222777 472 YAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEaRNTAWVSFDGRKRQEIRHGDSISITTSCYPL 550
Cdd:PRK03378 190 YSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSPN-RSDLEISCDSQIALPIQPGEEVLIRRSDYHL 267
ppnK PRK02649
NAD(+) kinase;
320-572 1.59e-18

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 86.57  E-value: 1.59e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 320 IDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVvkeLRGKKTa 399
Cdd:PRK02649  69 MKFAIVLGGDGTVLSAARQLAPCGIPLLTINTGHLGFLTEAYLNQLDEAIDQVLAGQYTIEERTMLTVSV---MRGDQL- 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 400 vhngLGENGSqaagldmdvgkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGAS 479
Cdd:PRK02649 145 ----RWEALS------------------LNEMVLHREPLTSMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGP 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 480 MIHPNVPAIMITPICPHSLSFRPIVVPAGVELKImlSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPv 559
Cdd:PRK02649 203 VITPDVPVLQLTPICPHSLASRALVFSDSEPVTV--FPATPERLVMVVDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDP- 279

                        250
                 ....*....|...
gi 312222777 560 sDWFESLAQCLHW 572
Cdd:PRK02649 280 -EFFRVLREKLGW 291
pnk PRK14075
NAD(+) kinase;
320-506 1.34e-15

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 77.08  E-value: 1.34e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 320 IDFIICLGGDGTLLYASSLFQGsvpPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKelrgkkta 399
Cdd:PRK14075  42 ADLIIVVGGDGTVLKAAKKVGT---PLVGFKAGRLGFLSSYTLEEIDRFLEDLKNWNFREEKRWFLKIESEL-------- 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 400 vhnglgengsqaagldmdvgkqaMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGAS 479
Cdd:PRK14075 111 -----------------------GNHLALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGSTAYSLSLGGP 167

                        170       180
                 ....*....|....*....|....*..
gi 312222777 480 MIHPNVPAIMITPICPHSLSFRPIVVP 506
Cdd:PRK14075 168 IILPNCEVFEITPIAPQFLATRSIVIP 194
ppnK PRK02231
NAD(+) kinase;
314-572 1.36e-15

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 77.15  E-value: 1.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 314 DDISNQIDFIICLGGDGTLL-YASSLFQGSVPpVMAFHLGSLGFLTPFSFENFQSQVTQVIE-GNAAVVLRSRLKVRVvk 391
Cdd:PRK02231  37 EEIGQRAQLAIVIGGDGNMLgRARVLAKYDIP-LIGINRGNLGFLTDIDPKNAYEQLEACLErGEFFVEERFLLEAKI-- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 392 ELRGKKTAVHNGLgengsqaagldmdvgkqamqyqvlNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTA 471
Cdd:PRK02231 114 ERNGKIIATSNAL------------------------NEVVIHPAKIAHMIDFHVYIDDKFAFSQRSDGLIISTPTGSTA 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 472 YAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITTSCYPLP 551
Cdd:PRK02231 170 YSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVIDGDSKISLRFAEYNTPQLEVSCDSQIALPFTPDDRVHVQKSPDKLR 249

                        250       260
                 ....*....|....*....|.
gi 312222777 552 SICVRDpvSDWFESLAQCLHW 572
Cdd:PRK02231 250 LLHLKN--YNYYNVLSSKLGW 268
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 320-374 7.58e-15

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 71.24  E-value: 7.58e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 312222777  320 IDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIE 374
Cdd:pfam01513  74 VDLIIVLGGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 287-550 7.49e-13

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 69.56  E-value: 7.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 287 VLEDPAIASDESFGAV---KKKFCTFREDyDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFE 363
Cdd:PRK03372  38 RVLDAEAVDLGATHPApddFRAMEVVDAD-PDAADGCELVLVLGGDGTILRAAELARAADVPVLGVNLGHVGFLAEAEAE 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 364 NFQSQVTQVIEGNAAVVLRSRLKVRVvkelRGKKTAVHNGLGengsqaagldmdvgkqamqyqvLNEVVIDRGPSSYLSN 443
Cdd:PRK03372 117 DLDEAVERVVDRDYRVEERMTLDVTV----RVGGEIVWRGWA----------------------LNEASLEKADREGMLE 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 444 VDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEArNTA 523
Cdd:PRK03372 171 VVLEVDGRPVSSFGCDGVLVSTPTGSTAYAFSAGGPVVWPDLEALLVVPLNAHALFARPLVVSPTSTVAVEILADT-SDA 249

                        250       260
                 ....*....|....*....|....*..
gi 312222777 524 WVSFDGRKRQEIRHGDSISITTSCYPL 550
Cdd:PRK03372 250 VLWCDGRRSVDLPPGARVEVRRGATPV 276
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 303-543 8.52e-11

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 62.91  E-value: 8.52e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 303 KKKFCTFREDYDDisNQIDFIICLGGDGTLLYASSLFQGSVPPVmAF---HLGSLGFLT---PFSFENFqsqVTQVIEGN 376
Cdd:PRK04885  21 KKYLKDFGFILDE--KNPDIVISVGGDGTLLSAFHRYENQLDKV-RFvgvHTGHLGFYTdwrPFEVDKL---VIALAKDP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 377 AAVVLRSRLKVRVVKElrgkktavhnglgeNGSQAAgldmdvgkqamqYQVLNEVVIDRgPSSYLSnVDVYLDGHLITTV 456
Cdd:PRK04885  95 GQVVSYPLLEVKITYE--------------DGEKEK------------YLALNEATIKR-IEGTLV-ADVYINGVLFERF 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 457 QGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICphSLS---FR----PIVVPAGVelKIMLSPEARNTAWVSFDg 529
Cdd:PRK04885 147 RGDGLCVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIA--SINnrvFRtlgsPLILPKHH--TITLKPVNDDDYQITVD- 221

                        250
                 ....*....|....
gi 312222777 530 rkRQEIRHGDSISI 543
Cdd:PRK04885 222 --HLTIKHKNVKSI 233
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 313-546 3.72e-04

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 42.50  E-value: 3.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 313 YDDIS-NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFL-TPFSFENFQSQVtqviegNAAVVLRSRLKVRVV 390
Cdd:PRK04761  18 YGDVPiEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLmNEYSEDDLLERI------AAAEPTVLHPLRMTA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 391 KELRGKktaVHNGLGEN-------GSQAAGLDMDV-GKQAMQyqvlnEVVidrgpssylsnvdvyldghlittvqGDGVI 462
Cdd:PRK04761  92 TDVSGE---VHEALAINevslfrqTRQAAKLRISIdGKVRME-----ELV-------------------------CDGVL 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 463 VSTPTGSTAYAAAAGASMIHPNVPAIMITPICPhslsFRP-----IVVPAGVELKI-MLSPEARNTAWVSfDGRkrqEIR 536
Cdd:PRK04761 139 VATPAGSTAYNLSAHGPILPLGSNLLALTPISP----FRPrrwrgALLPNSATVRFdVLEPDKRPVSAVA-DNT---EVR 210

                        250
                 ....*....|
gi 312222777 537 HGDSISITTS 546
Cdd:PRK04761 211 DVVEVTIRED 220
ppnK PRK03501
NAD kinase;
421-467 4.56e-03

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 39.19  E-value: 4.56e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 312222777 421 QAMQYQVLNEVVIDrgpSSYLSN--VDVYLDGHLITTVQGDGVIVSTPT 467
Cdd:PRK03501 113 GSTSFYCLNEFSIR---SSIIKTfvIDVYIDDLHFETFRGDGMVVSTPT 158
PLN02929 PLN02929
NADH kinase
 307-389 5.74e-03

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 39.25  E-value: 5.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 307 CTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPvmafhLG----------------------SLGFLTPFSFEN 364
Cdd:PLN02929  52 CVLRNELSQPIRDVDLVVAVGGDGTLLQASHFLDDSIPV-----LGvnsdptqkdeveeysdefdarrSTGHLCAATAED 126

                         90       100
                 ....*....|....*....|....*
gi 312222777 365 FQSQVTQVIEGNAAVVLRSRLKVRV 389
Cdd:PLN02929 127 FEQVLDDVLFGRLKPTELSRISTVV 151
ppnK PRK00561
NAD(+) kinase;
318-543 8.94e-03

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 38.32  E-value: 8.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 318 NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSF----ENFQSQVTQviegnaavvlrsrLKVRVVKEL 393
Cdd:PRK00561  32 DGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNEtdldQNFANKLDQ-------------LKFTQIDLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312222777 394 RgkktavhnglgengsqaagldmdVGKQAMQYQVLNEVVIDrgpSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYA 473
Cdd:PRK00561  99 E-----------------------VQIDDQIHLVLNELAVY---TNTAYPINIFIDNEFWEKYRGSGLLIGPRTGSTALA 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 312222777 474 AAAGASMIHPNVPAIMITPICP--HSlSF----RPIVVPAGVELKIMLSPEARNTAWVSF--DGRKRQEIRHGDSISI 543
Cdd:PRK00561 153 KSAKGAVIFPRIDVIQIIELNPllHP-NQttiqSPIILPIDTKVEFEIKKAFDHDQFPRFyaDGAKLRLGNSDTTIEI 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH