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solute carrier family 12 member 5 isoform 1 [Homo sapiens]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
44-1139
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1339.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 44 N PKESS P F I NSTDTEK G KEYDGK N MALF EE EM D TSPM V S SLL SG LA N YTN LP QG SR EHEEAE NN EG G K K KP V - Q A PRM G T 122
Cdd:TIGR00930 1 N TVDAV P R I EHYRNSE G QGGPKR N RPSL EE LH D LLDK V V SLL GP LA D YTN NG QG MK EHEEAE DA EG T K E KP P a G A VKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 123 F MGV YL PCL Q NI F GVILFLRL T W V VG I AGI ME S FCMVFI CC SC T ML T AI SMSAIATNGVV PA GG S YY M ISRSLGPEFGG A 202
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AGI GL S LLIILL CC CV T TI T GL SMSAIATNGVV KG GG A YY L ISRSLGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 203 V GL C F YLGTTF A G AMY IL G TI E IL L A ylfpama IFK a E DA S GEAAAML N NM R V YGT CVLTCMATVV F V G VKYV NK FALV F 282
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L D ------- LLR - E NG S KIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQVL F 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 283 L GC V I LSIL A I YA G V I KS AFD P P NFPICL LGN RTL S RH gfdvcaklawegnetvttrlwglfcssrflnatcdeyftrnn 362
Cdd:TIGR00930 233 L VI V L LSIL N I FV G T I IP AFD K P AKGFFG LGN EIF S EN ------------------------------------------ 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 363 vt E I Q GIPG AAS G likenlwssyltkgviversgmtsvgladgtpidmdhpyvfsdmtsy F TL L V GI Y FPSVTGI M AG S N 442
Cdd:TIGR00930 271 -- F I P GIPG PEG G ----------------------------------------------- F FS L F GI F FPSVTGI L AG A N 301
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 443 R SGDL R D A QK S IP T GT I LAI A TT SA VY IS SVVLFGAC IEGVVLR DK FGEA V N --------------------- G NL V V GT 501
Cdd:TIGR00930 302 I SGDL K D P QK A IP K GT L LAI L TT TV VY LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS 381
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 502 L AW P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA ISR D G I V PFLQ V FG H G KA - NGEP TW A L LLTA C I C E IG ILIA S L DEV 580
Cdd:TIGR00930 382 L VS P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LCK D N I Y PFLQ F FG K G YG k NGEP LR A Y LLTA F I A E GF ILIA E L NTI 461
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 581 API L S M FFL MC Y MFV N LA C AVQT LLR T P N WRPRF R YYHW T LS F LG M SLC L A L MF IC SW YY ALVAM L IA GLI YKY IE Y RGA 660
Cdd:TIGR00930 462 API I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKP 541
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 661 EKE WG DGIRG LS L S A A R Y A LLRLEE GPP H T KNWRPQ L LVL VRVD qdqn V VH P Q LL SLT SQ LKA GKGL T I V GSV LE G TF LE 740
Cdd:TIGR00930 542 DVN WG SSTQA LS Y S L A L Y S LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL DFA SQ FTK GKGL M I C GSV IQ G PR LE 617
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 741 NHPQ AQ R AE ES I RRLM E AE KVK G F CQ VV ISSN LR D GV S HLIQ SG GLG GLQH NT VLV G WPRN WRQ k EDHQT W RNF I ELVRE 820
Cdd:TIGR00930 618 CVKE AQ A AE AK I QTWL E KN KVK A F YA VV VADD LR E GV R HLIQ AS GLG RMKP NT LVM G YKKD WRQ - AEPRA W ETY I GIIHD 696
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 821 TTAG HLA LL V TK N VSMF P GNP -------------------------------------- ERFSE G S IDVWW I V H DGG MLM 862
Cdd:TIGR00930 697 AFDA HLA VV V VR N SEGL P ISV lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL 776
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 863 LLP F LL RHH KVW R KCK M RIF TV AQ M DD N S I Q M KKD LT T F LY HL RI T AEV E VV E M hes DI S A yt YEK T LV ME QRSQILKQM 942
Cdd:TIGR00930 777 LLP Y LL TTK KVW K KCK I RIF VG AQ K DD R S E Q E KKD MA T L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEEMIRPF 851
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 943 H L T K N E RE RE I qsitdesrgsirrknpantrlrlnvpeetagdseekpeeevqlihdqsapscpssspspgeepegege T 1022
Cdd:TIGR00930 852 R L H K T E KD RE A -------------------------------------------------------------------- K 863
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 1023 DP ekv HL TWTK DKSVAEKN kgpspvssegikdffsmkpewenl N QSNVR RMHTA VRLNE VIVKK SRDA K LV L L NM P G P PR 1102
Cdd:TIGR00930 864 DP --- KM TWTK PWKITDAE ------------------------ L QSNVR KSYRQ VRLNE LLLEY SRDA A LV V L SL P V P RK 916
1130 1140 1150
....*....|....*....|....*....|....*..
gi 198041678 1103 NRNG DE N YM EF LEVL T E H L DR V M LVRG GG R E V I T I YS 1139
Cdd:TIGR00930 917 GSIP DE L YM AW LEVL S E D L PP V L LVRG NH R N V L T F YS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
44-1139
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1339.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 44 N PKESS P F I NSTDTEK G KEYDGK N MALF EE EM D TSPM V S SLL SG LA N YTN LP QG SR EHEEAE NN EG G K K KP V - Q A PRM G T 122
Cdd:TIGR00930 1 N TVDAV P R I EHYRNSE G QGGPKR N RPSL EE LH D LLDK V V SLL GP LA D YTN NG QG MK EHEEAE DA EG T K E KP P a G A VKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 123 F MGV YL PCL Q NI F GVILFLRL T W V VG I AGI ME S FCMVFI CC SC T ML T AI SMSAIATNGVV PA GG S YY M ISRSLGPEFGG A 202
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AGI GL S LLIILL CC CV T TI T GL SMSAIATNGVV KG GG A YY L ISRSLGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 203 V GL C F YLGTTF A G AMY IL G TI E IL L A ylfpama IFK a E DA S GEAAAML N NM R V YGT CVLTCMATVV F V G VKYV NK FALV F 282
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L D ------- LLR - E NG S KIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQVL F 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 283 L GC V I LSIL A I YA G V I KS AFD P P NFPICL LGN RTL S RH gfdvcaklawegnetvttrlwglfcssrflnatcdeyftrnn 362
Cdd:TIGR00930 233 L VI V L LSIL N I FV G T I IP AFD K P AKGFFG LGN EIF S EN ------------------------------------------ 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 363 vt E I Q GIPG AAS G likenlwssyltkgviversgmtsvgladgtpidmdhpyvfsdmtsy F TL L V GI Y FPSVTGI M AG S N 442
Cdd:TIGR00930 271 -- F I P GIPG PEG G ----------------------------------------------- F FS L F GI F FPSVTGI L AG A N 301
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 443 R SGDL R D A QK S IP T GT I LAI A TT SA VY IS SVVLFGAC IEGVVLR DK FGEA V N --------------------- G NL V V GT 501
Cdd:TIGR00930 302 I SGDL K D P QK A IP K GT L LAI L TT TV VY LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS 381
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 502 L AW P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA ISR D G I V PFLQ V FG H G KA - NGEP TW A L LLTA C I C E IG ILIA S L DEV 580
Cdd:TIGR00930 382 L VS P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LCK D N I Y PFLQ F FG K G YG k NGEP LR A Y LLTA F I A E GF ILIA E L NTI 461
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 581 API L S M FFL MC Y MFV N LA C AVQT LLR T P N WRPRF R YYHW T LS F LG M SLC L A L MF IC SW YY ALVAM L IA GLI YKY IE Y RGA 660
Cdd:TIGR00930 462 API I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKP 541
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 661 EKE WG DGIRG LS L S A A R Y A LLRLEE GPP H T KNWRPQ L LVL VRVD qdqn V VH P Q LL SLT SQ LKA GKGL T I V GSV LE G TF LE 740
Cdd:TIGR00930 542 DVN WG SSTQA LS Y S L A L Y S LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL DFA SQ FTK GKGL M I C GSV IQ G PR LE 617
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 741 NHPQ AQ R AE ES I RRLM E AE KVK G F CQ VV ISSN LR D GV S HLIQ SG GLG GLQH NT VLV G WPRN WRQ k EDHQT W RNF I ELVRE 820
Cdd:TIGR00930 618 CVKE AQ A AE AK I QTWL E KN KVK A F YA VV VADD LR E GV R HLIQ AS GLG RMKP NT LVM G YKKD WRQ - AEPRA W ETY I GIIHD 696
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 821 TTAG HLA LL V TK N VSMF P GNP -------------------------------------- ERFSE G S IDVWW I V H DGG MLM 862
Cdd:TIGR00930 697 AFDA HLA VV V VR N SEGL P ISV lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL 776
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 863 LLP F LL RHH KVW R KCK M RIF TV AQ M DD N S I Q M KKD LT T F LY HL RI T AEV E VV E M hes DI S A yt YEK T LV ME QRSQILKQM 942
Cdd:TIGR00930 777 LLP Y LL TTK KVW K KCK I RIF VG AQ K DD R S E Q E KKD MA T L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEEMIRPF 851
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 943 H L T K N E RE RE I qsitdesrgsirrknpantrlrlnvpeetagdseekpeeevqlihdqsapscpssspspgeepegege T 1022
Cdd:TIGR00930 852 R L H K T E KD RE A -------------------------------------------------------------------- K 863
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 1023 DP ekv HL TWTK DKSVAEKN kgpspvssegikdffsmkpewenl N QSNVR RMHTA VRLNE VIVKK SRDA K LV L L NM P G P PR 1102
Cdd:TIGR00930 864 DP --- KM TWTK PWKITDAE ------------------------ L QSNVR KSYRQ VRLNE LLLEY SRDA A LV V L SL P V P RK 916
1130 1140 1150
....*....|....*....|....*....|....*..
gi 198041678 1103 NRNG DE N YM EF LEVL T E H L DR V M LVRG GG R E V I T I YS 1139
Cdd:TIGR00930 917 GSIP DE L YM AW LEVL S E D L PP V L LVRG NH R N V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
125-698
1.37e-44
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 168.65
E-value: 1.37e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 125 G V YLPC L QNIF G VI LF LRLTW V V G I AG IMESFCMVF I CCSCTM L TAI S MSA I A TNG V V p A GG S Y YMI SR S LGP EF G G A V G 204
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAGALLGYL I SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 205 L c F Y LGTTFAGAMYI L GTIE IL LAYLFPAMA I FKAE dasgeaaamlnnmr V Y G TCV L TCMATVVF VGVK YVNKFALV F LG 284
Cdd:pfam00324 80 W - N Y WLSWITVLALE L TAAS IL IQFWELVPD I PYLW -------------- V W G AVF L VLLTIINL VGVK WYGEAEFW F AL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 285 CV I LS I LAIYAGV I KSAFDPPN fpicllgnrtlsrhgfdvcaklawe GNETVTTR L WG lfcssrflnatcdeyftrnnvt 364
Cdd:pfam00324 145 IK I IA I IGFIIVG I ILLSGGNP ------------------------- NDGAIFRY L GD ---------------------- 177
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 365 eiqgi P G A asgli K E N L w SSYLT KG V I versgmtsvgladgtpidmdhp Y VF S dmtsyftllvg I Y F PSV TGI MAGSNRS 444
Cdd:pfam00324 178 ----- N G G ----- K N N F - PPGFG KG F I ---------------------- S VF V ----------- I A F FAF TGI ELVGIAA 213
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 445 G DLRDAQ KSIP TGTILA I ATTSAV YI S S VVLF G ACIEGVVLRDKFGE A VNGNLV V ------ G TLAWPS pw V I VIGSFFST 518
Cdd:pfam00324 214 G EVKNPE KSIP KAILQV I WRITIF YI L S LLAI G LLVPWNDPGLLNDS A SAASPF V iffkfl G ISGLAP -- L I NAVILTAA 291
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 519 CG A GLQ SL TGAP R L L QAIS RDG IV P F lq VFGHGKAN G E P TW A L L LTAC I CEIGI L I ASL de VAP I LSM F F L MCYMFVN L A 598
Cdd:pfam00324 292 LS A ANS SL YSGS R M L YSLA RDG LA P K -- FLKKVDKR G V P LR A I L VSMV I SLLAL L L ASL -- NPA I VFN F L L AISGLSG L I 367
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 599 CAVQTL L RTPNW R PR F R Y YHWTLSF L GMSLC L ALMFICSWYY A LVAM LI AGLI Y KYIEYR G AE K E WG D G IRGLSLSAARY 678
Cdd:pfam00324 368 VWGLIS L SHLRF R KA F K Y QGRSIDE L PFKAP L GPLGVILGLA A IIII LI IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLL 447
570 580
....*....|....*....|
gi 198041678 679 A L LR L EEGPP H T KNW R PQLL 698
Cdd:pfam00324 448 F L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
133-658
2.84e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 134.25
E-value: 2.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 133 N I F G VIL F LRLTWVV G I AG -- IMESFCMVFICC sct M L T A I S MSAI A TN gv V P - AGG S Y YMIS R S LGP EF G GAV G LCFY L 209
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AILAWLIAGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR R A LGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 210 GTTF A G A MYILGTIE i L L AY LFPA MAIF kaedasgeaaamlnnmr VYGTCVLTCMATVVFV GVK YVN K FALVFLGCVI L S 289
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SS LFPA GGSV ----------------- LIALVLILLLTLLNLR GVK ESA K VNNILTVLKL L V 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 290 I L AIYAGVI k S AFDP P NF picllgnrtlsrhgfdvcaklawegnetvttrlwglfcs SR FL N A T cdeyftrnnvteiqgi 369
Cdd:COG0531 162 L L LFIVVGL - F AFDP A NF --------------------------------------- TP FL P A G ---------------- 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 370 pgaasglikenlwssyltkgviver S G MTS V GL A dgtpidmdhpyvfsdmtsyftll VGIY F PSV TG IM A GS N RSGDLRD 449
Cdd:COG0531 186 ------------------------- G G LSG V LA A ----------------------- LALA F FAF TG FE A IA N LAEEAKN 217
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 450 AQKS IP TGT IL AIATTSAV YI SSVVLFG acie GVV LR D KFGEAVNGNLVVGTLAWPSP -- WV I VI G SFF S TC GA GLQ S LT 527
Cdd:COG0531 218 PKRN IP RAI IL SLLIVGVL YI LVSLALT ---- GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL 293
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 528 GA P RLL Q A IS RDG IV P fl Q VF GH - GKAN G E P TW A L LLT AC I CEIGI L I -- AS LDEV A PIL S MFF L MC Y MF V N LA CA V Q t L 604
Cdd:COG0531 294 GA S RLL Y A MA RDG LL P -- K VF AK v HPRF G T P VN A I LLT GV I ALLLL L L ga AS FTAL A SLA S VGV L LA Y LL V A LA VI V L - R 370
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 198041678 605 L R T P NWRPR FR YYHWTLSF LG MS LCL A L MFIC --- SWYYA LV AML I AG L I Y KYIEY R 658
Cdd:COG0531 371 R R R P DLPRP FR VPLPLIPI LG IL LCL F L LYLL gpg ALLIG LV LLA I GL L L Y LLYRR R 427
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
44-1139
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1339.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 44 N PKESS P F I NSTDTEK G KEYDGK N MALF EE EM D TSPM V S SLL SG LA N YTN LP QG SR EHEEAE NN EG G K K KP V - Q A PRM G T 122
Cdd:TIGR00930 1 N TVDAV P R I EHYRNSE G QGGPKR N RPSL EE LH D LLDK V V SLL GP LA D YTN NG QG MK EHEEAE DA EG T K E KP P a G A VKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 123 F MGV YL PCL Q NI F GVILFLRL T W V VG I AGI ME S FCMVFI CC SC T ML T AI SMSAIATNGVV PA GG S YY M ISRSLGPEFGG A 202
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AGI GL S LLIILL CC CV T TI T GL SMSAIATNGVV KG GG A YY L ISRSLGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 203 V GL C F YLGTTF A G AMY IL G TI E IL L A ylfpama IFK a E DA S GEAAAML N NM R V YGT CVLTCMATVV F V G VKYV NK FALV F 282
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L D ------- LLR - E NG S KIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQVL F 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 283 L GC V I LSIL A I YA G V I KS AFD P P NFPICL LGN RTL S RH gfdvcaklawegnetvttrlwglfcssrflnatcdeyftrnn 362
Cdd:TIGR00930 233 L VI V L LSIL N I FV G T I IP AFD K P AKGFFG LGN EIF S EN ------------------------------------------ 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 363 vt E I Q GIPG AAS G likenlwssyltkgviversgmtsvgladgtpidmdhpyvfsdmtsy F TL L V GI Y FPSVTGI M AG S N 442
Cdd:TIGR00930 271 -- F I P GIPG PEG G ----------------------------------------------- F FS L F GI F FPSVTGI L AG A N 301
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 443 R SGDL R D A QK S IP T GT I LAI A TT SA VY IS SVVLFGAC IEGVVLR DK FGEA V N --------------------- G NL V V GT 501
Cdd:TIGR00930 302 I SGDL K D P QK A IP K GT L LAI L TT TV VY LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS 381
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 502 L AW P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA ISR D G I V PFLQ V FG H G KA - NGEP TW A L LLTA C I C E IG ILIA S L DEV 580
Cdd:TIGR00930 382 L VS P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LCK D N I Y PFLQ F FG K G YG k NGEP LR A Y LLTA F I A E GF ILIA E L NTI 461
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 581 API L S M FFL MC Y MFV N LA C AVQT LLR T P N WRPRF R YYHW T LS F LG M SLC L A L MF IC SW YY ALVAM L IA GLI YKY IE Y RGA 660
Cdd:TIGR00930 462 API I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKP 541
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 661 EKE WG DGIRG LS L S A A R Y A LLRLEE GPP H T KNWRPQ L LVL VRVD qdqn V VH P Q LL SLT SQ LKA GKGL T I V GSV LE G TF LE 740
Cdd:TIGR00930 542 DVN WG SSTQA LS Y S L A L Y S LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL DFA SQ FTK GKGL M I C GSV IQ G PR LE 617
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 741 NHPQ AQ R AE ES I RRLM E AE KVK G F CQ VV ISSN LR D GV S HLIQ SG GLG GLQH NT VLV G WPRN WRQ k EDHQT W RNF I ELVRE 820
Cdd:TIGR00930 618 CVKE AQ A AE AK I QTWL E KN KVK A F YA VV VADD LR E GV R HLIQ AS GLG RMKP NT LVM G YKKD WRQ - AEPRA W ETY I GIIHD 696
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 821 TTAG HLA LL V TK N VSMF P GNP -------------------------------------- ERFSE G S IDVWW I V H DGG MLM 862
Cdd:TIGR00930 697 AFDA HLA VV V VR N SEGL P ISV lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL 776
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 863 LLP F LL RHH KVW R KCK M RIF TV AQ M DD N S I Q M KKD LT T F LY HL RI T AEV E VV E M hes DI S A yt YEK T LV ME QRSQILKQM 942
Cdd:TIGR00930 777 LLP Y LL TTK KVW K KCK I RIF VG AQ K DD R S E Q E KKD MA T L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEEMIRPF 851
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 943 H L T K N E RE RE I qsitdesrgsirrknpantrlrlnvpeetagdseekpeeevqlihdqsapscpssspspgeepegege T 1022
Cdd:TIGR00930 852 R L H K T E KD RE A -------------------------------------------------------------------- K 863
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 1023 DP ekv HL TWTK DKSVAEKN kgpspvssegikdffsmkpewenl N QSNVR RMHTA VRLNE VIVKK SRDA K LV L L NM P G P PR 1102
Cdd:TIGR00930 864 DP --- KM TWTK PWKITDAE ------------------------ L QSNVR KSYRQ VRLNE LLLEY SRDA A LV V L SL P V P RK 916
1130 1140 1150
....*....|....*....|....*....|....*..
gi 198041678 1103 NRNG DE N YM EF LEVL T E H L DR V M LVRG GG R E V I T I YS 1139
Cdd:TIGR00930 917 GSIP DE L YM AW LEVL S E D L PP V L LVRG NH R N V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
125-698
1.37e-44
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 168.65
E-value: 1.37e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 125 G V YLPC L QNIF G VI LF LRLTW V V G I AG IMESFCMVF I CCSCTM L TAI S MSA I A TNG V V p A GG S Y YMI SR S LGP EF G G A V G 204
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAGALLGYL I SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 205 L c F Y LGTTFAGAMYI L GTIE IL LAYLFPAMA I FKAE dasgeaaamlnnmr V Y G TCV L TCMATVVF VGVK YVNKFALV F LG 284
Cdd:pfam00324 80 W - N Y WLSWITVLALE L TAAS IL IQFWELVPD I PYLW -------------- V W G AVF L VLLTIINL VGVK WYGEAEFW F AL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 285 CV I LS I LAIYAGV I KSAFDPPN fpicllgnrtlsrhgfdvcaklawe GNETVTTR L WG lfcssrflnatcdeyftrnnvt 364
Cdd:pfam00324 145 IK I IA I IGFIIVG I ILLSGGNP ------------------------- NDGAIFRY L GD ---------------------- 177
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 365 eiqgi P G A asgli K E N L w SSYLT KG V I versgmtsvgladgtpidmdhp Y VF S dmtsyftllvg I Y F PSV TGI MAGSNRS 444
Cdd:pfam00324 178 ----- N G G ----- K N N F - PPGFG KG F I ---------------------- S VF V ----------- I A F FAF TGI ELVGIAA 213
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 445 G DLRDAQ KSIP TGTILA I ATTSAV YI S S VVLF G ACIEGVVLRDKFGE A VNGNLV V ------ G TLAWPS pw V I VIGSFFST 518
Cdd:pfam00324 214 G EVKNPE KSIP KAILQV I WRITIF YI L S LLAI G LLVPWNDPGLLNDS A SAASPF V iffkfl G ISGLAP -- L I NAVILTAA 291
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 519 CG A GLQ SL TGAP R L L QAIS RDG IV P F lq VFGHGKAN G E P TW A L L LTAC I CEIGI L I ASL de VAP I LSM F F L MCYMFVN L A 598
Cdd:pfam00324 292 LS A ANS SL YSGS R M L YSLA RDG LA P K -- FLKKVDKR G V P LR A I L VSMV I SLLAL L L ASL -- NPA I VFN F L L AISGLSG L I 367
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 599 CAVQTL L RTPNW R PR F R Y YHWTLSF L GMSLC L ALMFICSWYY A LVAM LI AGLI Y KYIEYR G AE K E WG D G IRGLSLSAARY 678
Cdd:pfam00324 368 VWGLIS L SHLRF R KA F K Y QGRSIDE L PFKAP L GPLGVILGLA A IIII LI IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLL 447
570 580
....*....|....*....|
gi 198041678 679 A L LR L EEGPP H T KNW R PQLL 698
Cdd:pfam00324 448 F L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
133-658
2.84e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 134.25
E-value: 2.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 133 N I F G VIL F LRLTWVV G I AG -- IMESFCMVFICC sct M L T A I S MSAI A TN gv V P - AGG S Y YMIS R S LGP EF G GAV G LCFY L 209
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AILAWLIAGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR R A LGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 210 GTTF A G A MYILGTIE i L L AY LFPA MAIF kaedasgeaaamlnnmr VYGTCVLTCMATVVFV GVK YVN K FALVFLGCVI L S 289
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SS LFPA GGSV ----------------- LIALVLILLLTLLNLR GVK ESA K VNNILTVLKL L V 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 290 I L AIYAGVI k S AFDP P NF picllgnrtlsrhgfdvcaklawegnetvttrlwglfcs SR FL N A T cdeyftrnnvteiqgi 369
Cdd:COG0531 162 L L LFIVVGL - F AFDP A NF --------------------------------------- TP FL P A G ---------------- 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 370 pgaasglikenlwssyltkgviver S G MTS V GL A dgtpidmdhpyvfsdmtsyftll VGIY F PSV TG IM A GS N RSGDLRD 449
Cdd:COG0531 186 ------------------------- G G LSG V LA A ----------------------- LALA F FAF TG FE A IA N LAEEAKN 217
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 450 AQKS IP TGT IL AIATTSAV YI SSVVLFG acie GVV LR D KFGEAVNGNLVVGTLAWPSP -- WV I VI G SFF S TC GA GLQ S LT 527
Cdd:COG0531 218 PKRN IP RAI IL SLLIVGVL YI LVSLALT ---- GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL 293
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 528 GA P RLL Q A IS RDG IV P fl Q VF GH - GKAN G E P TW A L LLT AC I CEIGI L I -- AS LDEV A PIL S MFF L MC Y MF V N LA CA V Q t L 604
Cdd:COG0531 294 GA S RLL Y A MA RDG LL P -- K VF AK v HPRF G T P VN A I LLT GV I ALLLL L L ga AS FTAL A SLA S VGV L LA Y LL V A LA VI V L - R 370
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 198041678 605 L R T P NWRPR FR YYHWTLSF LG MS LCL A L MFIC --- SWYYA LV AML I AG L I Y KYIEY R 658
Cdd:COG0531 371 R R R P DLPRP FR VPLPLIPI LG IL LCL F L LYLL gpg ALLIG LV LLA I GL L L Y LLYRR R 427
SLC12
pfam03522 Solute carrier family 12;
712-1139
1.94e-23
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 104.24
E-value: 1.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 712 P Q L LSLTSQLKAGKG L T I V G S V LE G T flen HP Q AQ R A E -- ESIR R LMEAE K V K G F CQV V ISS NLR D G VSH L I Q SG GLG G L 789
Cdd:pfam03522 2 P A L VDFAHLITKNVS L M I C G H V VK G R ---- LS Q KL R S E lq KKAY R WLRKR K I K A F YAL V DGD NLR E G AQA L L Q AS GLG K L 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 790 QH N TV L V G WPRN WR ----------------------------------------------------------- Q KEDH Q T 810
Cdd:pfam03522 78 KP N IL L M G YKSD WR tcdkeeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyae Q SSEE Q S 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 811 WR N FIELVRETTAGH ------- LALLV TKN V S MFPGNPE ------------------------------ RFSE G S IDVWW 853
Cdd:pfam03522 158 TS N SKQDDDKSKLSK kdsnlsl SPDKS TKN P S GKDSSKS dklkkkspsiilrtasnekeilnnitqfqk KQKK G T IDVWW 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 854 IVH DGG MLM LLP FL L RHHKV W RK CK M R I F TVAQMD D NSIQMKKDLTTF L YHL RI T - AEVE V V emhe S DI SAYTYEK T lvm 932
Cdd:pfam03522 238 LYD DGG LTL LLP YI L STRSK W SD CK L R V F ALGNRK D ELEEEQRNMASL L SKF RI D y SDLT V I ---- P DI TKKPKKE T --- 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 933 eqrsqil K QMH -- L TKNE R ER E iqsitdesrgsirrknpantrlrlnvpeetagds EE K P EE EVQL I hdqsapscpsssp 1010
Cdd:pfam03522 311 ------- K KFF de L IEPF R LH E ---------------------------------- DD K E EE SAEK I ------------- 336
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 1011 spgeepegege TD P E KVH L twt K D K S vaeknkgpspvssegikdffsmkpewenlnqsnv R R M hta V RL N E VIVKK S R DA 1090
Cdd:pfam03522 337 ----------- TD S E LEA L --- K E K T ---------------------------------- N R Q --- L RL R E LLLEH S S DA 365
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 198041678 1091 K L VLLNM P G P PRNRNGDEN YM EF LE V LT EH L DRVM LVRG GGRE V I T I YS 1139
Cdd:pfam03522 366 N L IVMTL P M P RKGTVSAPL YM AW LE T LT KD L PPFL LVRG NQTS V L T F YS 414
AA_permease_2
pfam13520 Amino acid permease;
407-655
1.68e-14
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 76.97
E-value: 1.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 407 PIDMD H PYVFSDMTSY F TLLV G IYF p S V TG IMAGS N R S GDLR da QKSI P TGTILAIATTSAV YI SSVVL F GACI -- EGVV 484
Cdd:pfam13520 175 LSGEW H TFFPDGWPGV F AGFL G VLW - S F TG FESAA N V S EEVK -- KRNV P KAIFIGVIIVGVL YI LVNIA F FGVV pd DEIA 251
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 485 L RD ------- KFGE AV N G NLVVG tlawpspw VI VI GSFF S TC GA GLQSLT GA P RLL Q A IS RDG IV PF LQV F GHGKAN G E P 557
Cdd:pfam13520 252 L SS glgqvaa LLFQ AV G G KWGAI -------- IV VI LLAL S LL GA VNTAIV GA S RLL Y A LA RDG VL PF SRF F AKVNKF G S P 323
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 558 TW A LL LTA CICE I GI L IAS L DEV A PI ---- LS MFFLMCYMFVNLACAV qt L LR TPNWRPRFRYYH W TLSFL G M s L CLALM 633
Cdd:pfam13520 324 IR A II LTA ILSL I LL L LFL L SPA A YN alls LS AYGYLLSYLLPIIGLL -- I LR KKRPDLGRIPGR W PVAIF G I - L FSLFL 400
250 260
....*....|....*....|..
gi 198041678 634 FICSWYYALVAMLIAG L I Y KY I 655
Cdd:pfam13520 401 IVALFFPPVGPATGSS L N Y AI I 422
2A0308
TIGR00911 L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
445-646
4.19e-04
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273332 [Multi-domain]
Cd Length: 501
Bit Score: 44.35
E-value: 4.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 445 GDLRDAQKSI P TGT I LAIATTSAV Y ISSVVLFGACIEGVV L RDKFGE AV N - G NLVV G TLA W PS P wv IVI G sf F S TC G AGL 523
Cdd:TIGR00911 259 EEVKNPYRTL P IAI I ISMPIVTFI Y VLTNIAYFTVLSPEE L LASLAV AV D f G ERLL G VMS W AM P -- ALV G -- L S CF G SVN 334
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041678 524 Q SL TGAP RL LQAIS R D G IV P F L QVFG H G K AN g E P TWA LL LT aci C EIGI L IASLDEVAPILSMFFLMCYM F VN LA C A VQT 603
Cdd:TIGR00911 335 G SL FSSS RL FFVGG R E G HL P S L LSMI H V K RL - T P LPS LL IV --- C TLTL L MLFSGDIYSLINLISFANWL F NA LA V A GLL 410
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 198041678 604 L LR -- T P NWRPRFR yyhwtlsflg MS L CLALM F IC S WYYALVAM L 646
Cdd:TIGR00911 411 W LR yk R P EMNRPIK ---------- VP L FFPVF F LL S CLFLIILS L 445
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
