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Conserved domains on  [gi|194328687|ref|NP_001123631|]
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storkhead-box protein 1 isoform b [Homo sapiens]

Protein Classification

storkhead-box protein( domain architecture ID 10563160)

storkhead-box protein contains a winged helix domain that binds DNA and functions as a transcription factor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Stork_head pfam10264
Winged helix Storkhead-box1 domain; This is the conserved N-terminal winged helix domain of ...
 111-189 4.92e-47

Winged helix Storkhead-box1 domain; This is the conserved N-terminal winged helix domain of Storkhead-box1 protein which is likely to be a DNA binding domain. In humans the full-length protein controls polyploidization of extravillus trophoblast and is implicated in pre-eclampsia.


:

Pssm-ID: 431182  Cd Length: 79  Bit Score: 150.13  E-value: 4.92e-47
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194328687  111 MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDILYTTLGTLIKERKIYHTGEGYFIVTP 189
Cdd:pfam10264   1 MSPISQSQFTPLAEALCDAILDLNSAGQVATLDTIREALKKHFPGIAPPSQEVVYDTLGSLIRERKIYHTGEGYFVVTP 79
 
Name Accession Description Interval E-value
Stork_head pfam10264
Winged helix Storkhead-box1 domain; This is the conserved N-terminal winged helix domain of ...
 111-189 4.92e-47

Winged helix Storkhead-box1 domain; This is the conserved N-terminal winged helix domain of Storkhead-box1 protein which is likely to be a DNA binding domain. In humans the full-length protein controls polyploidization of extravillus trophoblast and is implicated in pre-eclampsia.


Pssm-ID: 431182  Cd Length: 79  Bit Score: 150.13  E-value: 4.92e-47
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194328687  111 MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDILYTTLGTLIKERKIYHTGEGYFIVTP 189
Cdd:pfam10264   1 MSPISQSQFTPLAEALCDAILDLNSAGQVATLDTIREALKKHFPGIAPPSQEVVYDTLGSLIRERKIYHTGEGYFVVTP 79
 
Name Accession Description Interval E-value
Stork_head pfam10264
Winged helix Storkhead-box1 domain; This is the conserved N-terminal winged helix domain of ...
 111-189 4.92e-47

Winged helix Storkhead-box1 domain; This is the conserved N-terminal winged helix domain of Storkhead-box1 protein which is likely to be a DNA binding domain. In humans the full-length protein controls polyploidization of extravillus trophoblast and is implicated in pre-eclampsia.


Pssm-ID: 431182  Cd Length: 79  Bit Score: 150.13  E-value: 4.92e-47
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194328687  111 MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDILYTTLGTLIKERKIYHTGEGYFIVTP 189
Cdd:pfam10264   1 MSPISQSQFTPLAEALCDAILDLNSAGQVATLDTIREALKKHFPGIAPPSQEVVYDTLGSLIRERKIYHTGEGYFVVTP 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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