NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462588888|ref|XP_054202054|]
View 

target of Nesh-SH3 isoform X63 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 889-980 9.76e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 59.43  E-value: 9.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  889 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 966
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                           90
                   ....*....|....
gi 2462588888  967 LGEGPVSNTVAFST 980
Cdd:cd00063     80 GGESPPSESVTVTT 93
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 509-716 1.01e-09

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 62.78  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  509 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVthtkPAPKQTPRAPPKPKTSPRPRIPQ---T 580
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEF----PKDPKHPKDPEEPKKPKRPRSAQrptR 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  581 QPVPKVPQ--RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI--------SPSPSQEEL 650
Cdd:PTZ00449   609 PKSPKLPEllDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFkekfyddyLDAAAKSKE 688

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  651 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhrfYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 716
Cdd:PTZ00449   689 TKTTVVLDESFESILKETLPETPGTPFTTPRP---LPPKLPRDEEFPFEPI------GDPDAEQPD 745
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 319-623 4.47e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  319 PAESKTPEvekisARPttvtPETVPRSTKPTTSSALDVSETTLVLSKRTPETLQTILIPQFELPLSTLASSEKPW--IVP 396
Cdd:PHA03247  2702 PPPPPTPE-----PAP----HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPapAPP 2772

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  397 TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSP 476
Cdd:PHA03247  2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  477 E--MQP-----TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTItPKISKSPEPTWTTPAPGKTQFISLKPKIPLS 549
Cdd:PHA03247  2853 GgsVAPggdvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462588888  550 PEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 623
Cdd:PHA03247  2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
706-985 5.93e-05

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 47.30  E-value: 5.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  706 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 785
Cdd:COG3401     48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  786 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 862
Cdd:COG3401    128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  863 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 941
Cdd:COG3401    208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462588888  942 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 985
Cdd:COG3401    283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 124-202 1.06e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.83  E-value: 1.06e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888   124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 2462588888   200 GVK 202
Cdd:smart00060   73 RVR 75
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 889-980 9.76e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 59.43  E-value: 9.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  889 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 966
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                           90
                   ....*....|....
gi 2462588888  967 LGEGPVSNTVAFST 980
Cdd:cd00063     80 GGESPPSESVTVTT 93
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 509-716 1.01e-09

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 62.78  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  509 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVthtkPAPKQTPRAPPKPKTSPRPRIPQ---T 580
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEF----PKDPKHPKDPEEPKKPKRPRSAQrptR 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  581 QPVPKVPQ--RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI--------SPSPSQEEL 650
Cdd:PTZ00449   609 PKSPKLPEllDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFkekfyddyLDAAAKSKE 688

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  651 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhrfYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 716
Cdd:PTZ00449   689 TKTTVVLDESFESILKETLPETPGTPFTTPRP---LPPKLPRDEEFPFEPI------GDPDAEQPD 745
PHA03247 PHA03247
large tegument protein UL36; Provisional
 319-623 4.47e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  319 PAESKTPEvekisARPttvtPETVPRSTKPTTSSALDVSETTLVLSKRTPETLQTILIPQFELPLSTLASSEKPW--IVP 396
Cdd:PHA03247  2702 PPPPPTPE-----PAP----HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPapAPP 2772

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  397 TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSP 476
Cdd:PHA03247  2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  477 E--MQP-----TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTItPKISKSPEPTWTTPAPGKTQFISLKPKIPLS 549
Cdd:PHA03247  2853 GgsVAPggdvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462588888  550 PEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 623
Cdd:PHA03247  2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 890-970 2.08e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 52.62  E-value: 2.08e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888   890 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 967
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 2462588888   968 GEG 970
Cdd:smart00060   81 GEG 83
PHA03247 PHA03247
large tegument protein UL36; Provisional
 543-892 6.16e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 6.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  543 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP----RPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP 618
Cdd:PHA03247  2588 RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPpdthAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRA 2667

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  619 YPEVSQSEP-APLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKP 697
Cdd:PHA03247  2668 RRLGRAAQAsSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG 2747

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  698 HIRPVLNRTTTRPTRPK--PSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPpnn 775
Cdd:PHA03247  2748 PATPGGPARPARPPTTAgpPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP--- 2824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  776 VTGKPGSAGIISSGPITTPPLRSTPRPT------GTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPrfk 849
Cdd:PHA03247  2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLggsvapGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALP--- 2901

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2462588888  850 gphvryiqkPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPT 892
Cdd:PHA03247  2902 ---------PDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 329-609 2.33e-07

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 54.97  E-value: 2.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  329 KISARPTTVTPETVpRSTKPTTSSALdvseTTLVLSKRTPETLQTILIPQFELPL----STLASSEKPWIVPTAKISEDS 404
Cdd:pfam17823  113 RALAAAASSSPSSA-AQSLPAAIAAL----PSEAFSAPRAAACRANASAAPRAAIaaasAPHAASPAPRTAASSTTAASS 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  405 KVLQPQTATYDVFSSPTT-SDEPEISDSYTAT----SDRILDSIPPKTS--RTLEQPRATLAPSETPFVPQKLEIFTSPE 477
Cdd:pfam17823  188 TTAASSAPTTAASSAPATlTPARGISTAATATghpaAGTALAAVGNSSPaaGTVTAAVGTVTPAALATLAAAAGTVASAA 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  478 MQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT------PKISKSPEPTwttPAPGKTQFISLKPKIPLSPE 551
Cdd:pfam17823  268 GTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPIIqvstdqPVHNTAGEPT---PSPSNTTLEPNTPKSVASTN 344

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  552 ---VTHTKPAPKQTPRAP-PKPKTSPRPRI----PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 609
Cdd:pfam17823  345 lavVTTTKAQAKEPSASPvPVLHTSMIPEVeatsPTTQPSPLLPTQGAAGPGILLAPEQVATEATA 410
fn3 pfam00041
Fibronectin type III domain;
890-973 8.35e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 45.10  E-value: 8.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  890 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 966
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78


                   ....*..
gi 2462588888  967 LGEGPVS 973
Cdd:pfam00041   79 GGEGPPS 85
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
706-985 5.93e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 47.30  E-value: 5.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  706 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 785
Cdd:COG3401     48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  786 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 862
Cdd:COG3401    128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  863 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 941
Cdd:COG3401    208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462588888  942 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 985
Cdd:COG3401    283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
884-1028 8.35e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 46.53  E-value: 8.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  884 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 961
Cdd:COG3401    324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462588888  962 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1028
Cdd:COG3401    398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 124-202 1.06e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.83  E-value: 1.06e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888   124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 2462588888   200 GVK 202
Cdd:smart00060   73 RVR 75
fn3 pfam00041
Fibronectin type III domain;
123-202 1.13e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 2462588888  200 GVK 202
Cdd:pfam00041   72 RVQ 74
DUF4813 pfam16072
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. ...
 525-655 2.86e-04

Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 345 and 672 amino acids in length.


Pssm-ID: 435117 [Multi-domain]  Cd Length: 288  Bit Score: 44.36  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  525 PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSY 604
Cdd:pfam16072  146 PGSVTTTSAGSGTTVINAGGQQPAAPAAPAYPVAPAAYPAQAPAAAPAPAPGAPQTPLAPLNPVAAAPAAAAGAAAAPVV 225

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462588888  605 TTPAPKDVlLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLE 655
Cdd:pfam16072  226 AAAAPAAA-APPPPAPAAPPADAAPPAPGGIICVPVRVPEPDPKDATKTIE 275
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 123-202 3.75e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 40.56  E-value: 3.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73


                   ..
gi 2462588888  201 VK 202
Cdd:cd00063     74 VR 75
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 522-610 2.76e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.76  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  522 SKSPEPTWTTPAPGKT-----QFISLKPKIPLSP-------EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 589
Cdd:COG3266    255 LKAPSQASSASAPATTslgeqQEVSLPPAVAAQPaaaaaaqPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKPVVTETAA 334

                           90       100
                   ....*....|....*....|.
gi 2462588888  590 VTAkpktsPSPEVSYTTPAPK 610
Cdd:COG3266    335 PAA-----PAPEAAAAAAAPA 350
 
Name Accession Description Interval E-value
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 889-980 9.76e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 59.43  E-value: 9.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  889 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 966
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                           90
                   ....*....|....
gi 2462588888  967 LGEGPVSNTVAFST 980
Cdd:cd00063     80 GGESPPSESVTVTT 93
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 509-716 1.01e-09

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 62.78  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  509 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVthtkPAPKQTPRAPPKPKTSPRPRIPQ---T 580
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEF----PKDPKHPKDPEEPKKPKRPRSAQrptR 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  581 QPVPKVPQ--RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI--------SPSPSQEEL 650
Cdd:PTZ00449   609 PKSPKLPEllDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFkekfyddyLDAAAKSKE 688

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  651 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhrfYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 716
Cdd:PTZ00449   689 TKTTVVLDESFESILKETLPETPGTPFTTPRP---LPPKLPRDEEFPFEPI------GDPDAEQPD 745
PHA03247 PHA03247
large tegument protein UL36; Provisional
 444-812 1.53e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.65  E-value: 1.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  444 PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK--- 520
Cdd:PHA03247  2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRrra 2687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  521 ---------ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP---RIPQTQPVPKVPQ 588
Cdd:PHA03247  2688 arptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggpARPARPPTTAGPP 2767

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  589 RVT--AKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFT 666
Cdd:PHA03247  2768 APAppAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  667 TKIPRTTELA---------KTTQAPHRFYTTVRPRTSDKPhiRPVLNRTTT-------RPTRPKPSGMPSGNGVGTGVKQ 730
Cdd:PHA03247  2848 PSLPLGGSVApggdvrrrpPSRSPAAKPAAPARPPVRRLA--RPAVSRSTEsfalppdQPERPPQPQAPPPPQPQPQPPP 2925

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  731 APRPSGADRnvsvdsTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGII-----SSGPITTPPLRSTPRPTGT 805
Cdd:PHA03247  2926 PPQPQPPPP------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPrfrvpQPAPSREAPASSTPPLTGH 2999


                   ....*..
gi 2462588888  806 PLERIET 812
Cdd:PHA03247  3000 SLSRVSS 3006
PHA03247 PHA03247
large tegument protein UL36; Provisional
 319-623 4.47e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 61.11  E-value: 4.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  319 PAESKTPEvekisARPttvtPETVPRSTKPTTSSALDVSETTLVLSKRTPETLQTILIPQFELPLSTLASSEKPW--IVP 396
Cdd:PHA03247  2702 PPPPPTPE-----PAP----HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPapAPP 2772

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  397 TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSP 476
Cdd:PHA03247  2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  477 E--MQP-----TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTItPKISKSPEPTWTTPAPGKTQFISLKPKIPLS 549
Cdd:PHA03247  2853 GgsVAPggdvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462588888  550 PEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 623
Cdd:PHA03247  2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 890-970 2.08e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 52.62  E-value: 2.08e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888   890 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 967
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 2462588888   968 GEG 970
Cdd:smart00060   81 GEG 83
PHA03247 PHA03247
large tegument protein UL36; Provisional
 444-734 3.03e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 3.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  444 PPKTSRTLE-QPRATLAPSETPFVPQKL-EIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI 521
Cdd:PHA03247  2701 PPPPPPTPEpAPHALVSATPLPPGPAAArQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP 2780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  522 SKSPEP---------------------TWTTPAPGKTQFISLKPKIPLSPEVTHTkPAPKQTPRAPPKPKTSP------- 573
Cdd:PHA03247  2781 RRLTRPavaslsesreslpspwdpadpPAAVLAPAAALPPAASPAGPLPPPTSAQ-PTAPPPPPGPPPPSLPLggsvapg 2859

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  574 ---RPRIPQTQPVPKV------PQRVTAKPKTSPSPEvSYTTPAPKdvllPHKPYPEVSQSEPAPLETRGIPFIPMISPs 644
Cdd:PHA03247  2860 gdvRRRPPSRSPAAKPaaparpPVRRLARPAVSRSTE-SFALPPDQ----PERPPQPQAPPPPQPQPQPPPPPQPQPPP- 2933

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  645 PSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTtqAPHRfYTTVRPRTSDKPHIRPVLNRTTTRPTRPKPSGMPS-GNG 723
Cdd:PHA03247  2934 PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL--VPGR-VAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSwASS 3010

                          330
                   ....*....|.
gi 2462588888  724 VGTGVKQAPRP 734
Cdd:PHA03247  3011 LALHEETDPPP 3021
PHA03247 PHA03247
large tegument protein UL36; Provisional
 454-869 5.03e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 5.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  454 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 531
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  532 PAPGKTQFISLKPKIPLSPEVTHTKPAPkqtPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKD 611
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAP---GRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT 2707

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  612 VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTelakttqAPHRFYTTVRP 691
Cdd:PHA03247  2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP-------APPAAPAAGPP 2780

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  692 RTSDKPHIRPVLNRTTTRPTRPKPSGMPSgngVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPL 771
Cdd:PHA03247  2781 RRLTRPAVASLSESRESLPSPWDPADPPA---AVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  772 PPNNVT--GKPGSAGIISSGPiTTPPLRSTPRPtgtPLERIETDIKQPtvPASGEELEniTDFSSSPTRETDPLGKPRFK 849
Cdd:PHA03247  2858 PGGDVRrrPPSRSPAAKPAAP-ARPPVRRLARP---AVSRSTESFALP--PDQPERPP--QPQAPPPPQPQPQPPPPPQP 2929

                          410       420
                   ....*....|....*....|
gi 2462588888  850 GPHVRYIQKPDNSPCSITDS 869
Cdd:PHA03247  2930 QPPPPPPPRPQPPLAPTTDP 2949
PHA03247 PHA03247
large tegument protein UL36; Provisional
 543-892 6.16e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 6.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  543 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP----RPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP 618
Cdd:PHA03247  2588 RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPpdthAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRA 2667

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  619 YPEVSQSEP-APLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKP 697
Cdd:PHA03247  2668 RRLGRAAQAsSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG 2747

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  698 HIRPVLNRTTTRPTRPK--PSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPpnn 775
Cdd:PHA03247  2748 PATPGGPARPARPPTTAgpPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASP--- 2824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  776 VTGKPGSAGIISSGPITTPPLRSTPRPT------GTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPrfk 849
Cdd:PHA03247  2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLggsvapGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALP--- 2901

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 2462588888  850 gphvryiqkPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPT 892
Cdd:PHA03247  2902 ---------PDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 329-609 2.33e-07

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 54.97  E-value: 2.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  329 KISARPTTVTPETVpRSTKPTTSSALdvseTTLVLSKRTPETLQTILIPQFELPL----STLASSEKPWIVPTAKISEDS 404
Cdd:pfam17823  113 RALAAAASSSPSSA-AQSLPAAIAAL----PSEAFSAPRAAACRANASAAPRAAIaaasAPHAASPAPRTAASSTTAASS 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  405 KVLQPQTATYDVFSSPTT-SDEPEISDSYTAT----SDRILDSIPPKTS--RTLEQPRATLAPSETPFVPQKLEIFTSPE 477
Cdd:pfam17823  188 TTAASSAPTTAASSAPATlTPARGISTAATATghpaAGTALAAVGNSSPaaGTVTAAVGTVTPAALATLAAAAGTVASAA 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  478 MQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT------PKISKSPEPTwttPAPGKTQFISLKPKIPLSPE 551
Cdd:pfam17823  268 GTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPIIqvstdqPVHNTAGEPT---PSPSNTTLEPNTPKSVASTN 344

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  552 ---VTHTKPAPKQTPRAP-PKPKTSPRPRI----PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 609
Cdd:pfam17823  345 lavVTTTKAQAKEPSASPvPVLHTSMIPEVeatsPTTQPSPLLPTQGAAGPGILLAPEQVATEATA 410
fn3 pfam00041
Fibronectin type III domain;
890-973 8.35e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 45.10  E-value: 8.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  890 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 966
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78


                   ....*..
gi 2462588888  967 LGEGPVS 973
Cdd:pfam00041   79 GGEGPPS 85
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 543-638 4.02e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 47.63  E-value: 4.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  543 KPKIPLSPEVTHTKPAPKQTPraPPKPKTSPRpripqtQPVPKVPQRVTAKPKTSPSPEvSYTTPAPKDVLLPHKPYPEV 622
Cdd:PRK14954   375 RNDGGVAPSPAGSPDVKKKAP--EPDLPQPDR------HPGPAKPEAPGARPAELPSPA-SAPTPEQQPPVARSAPLPPS 445

                           90
                   ....*....|....*.
gi 2462588888  623 SQSEPAPLETRGIPFI 638
Cdd:PRK14954   446 PQASAPRNVASGKPGV 461
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
706-985 5.93e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 47.30  E-value: 5.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  706 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 785
Cdd:COG3401     48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  786 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 862
Cdd:COG3401    128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  863 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 941
Cdd:COG3401    208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462588888  942 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 985
Cdd:COG3401    283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
884-1028 8.35e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 46.53  E-value: 8.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  884 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 961
Cdd:COG3401    324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462588888  962 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1028
Cdd:COG3401    398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 124-202 1.06e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.83  E-value: 1.06e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888   124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 2462588888   200 GVK 202
Cdd:smart00060   73 RVR 75
fn3 pfam00041
Fibronectin type III domain;
123-202 1.13e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 2462588888  200 GVK 202
Cdd:pfam00041   72 RVQ 74
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 510-626 1.26e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 45.96  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  510 RTTSAGT-------ITPKISKSPEPTWTTPAPGktqfislkpkiplSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQP 582
Cdd:PRK14950   342 RTTSYGQlplelavIEALLVPVPAPQPAKPTAA-------------APSPVRPTPAPSTRPKAAAAANIPPKEPVRETAT 408

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2462588888  583 VPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSE 626
Cdd:PRK14950   409 PPPVPPRPVAPPVPHTPESAPKLTRAAIPVDEKPKYTPPAPPKE 452
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 516-651 1.29e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 46.23  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  516 TITPKISKSPEPTWTTPAPGKTQFISLKP-KIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPrIPQTQPVPKVPQRVTAKP 594
Cdd:PRK10263   368 TGEPVIAPAPEGYPQQSQYAQPAVQYNEPlQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQP-AQQPYYAPAPEQPVAGNA 446

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2462588888  595 KTSPSPEVSYttpAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQ 651
Cdd:PRK10263   447 WQAEEQQSTF---APQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETK 500
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 404-735 1.46e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 46.23  E-value: 1.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  404 SKVLQPQTATYDVFSSPTTSDEP--------EISDSYTATSDRILDSIP-PKTSRTLEQPRATLAPSETPFVPQKLeIFT 474
Cdd:PRK10263   297 NRATQPEYDEYDPLLNGAPITEPvavaaaatTATQSWAAPVEPVTQTPPvASVDVPPAQPTVAWQPVPGPQTGEPV-IAP 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  475 SPEM---QPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEptWTTPAPGKTQFISLKPKIPLSPE 551
Cdd:PRK10263   376 APEGypqQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQ--QPYYAPAPEQPVAGNAWQAEEQQ 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  552 vTHTKPAPKQTPRappKPKTSPRPRIPQTQPVPKVPQrvtaKPKTSPSPEVSYTTPAPKdvllPHKPYPEVSQSEPAPLE 631
Cdd:PRK10263   454 -STFAPQSTYQTE---QTYQQPAAQEPLYQQPQPVEQ----QPVVEPEPVVEETKPARP----PLYYFEEVEEKRARERE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  632 TRGIPFIPMisPSPSQEElqttlEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRPT 711
Cdd:PRK10263   522 QLAAWYQPI--PEPVKEP-----EPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGP 594

                          330       340
                   ....*....|....*....|....
gi 2462588888  712 RPKPSgmpsgNGVGtgvKQAPRPS 735
Cdd:PRK10263   595 RPQVK-----EGIG---PQLPRPK 610
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 454-864 2.63e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 2.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  454 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAP-QQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTP 532
Cdd:PHA03307    49 ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPaNESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPP 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  533 APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPqtqPVPKVPQrvTAKPKTSPSPEVSYTTPAPKDV 612
Cdd:PHA03307   129 SPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAAL---PLSSPEE--TARAPSSPPAEPPPSTPPAAAS 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  613 LLPHKPYPEVS--QSEPAPLETRGIPFIPMISPSPSqeelqttLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR 690
Cdd:PHA03307   204 PRPPRRSSPISasASSPAPAPGRSAADDAGASSSDS-------SSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWN 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  691 PRTSDKPHIRPvlnRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPrrkp 770
Cdd:PHA03307   277 GPSSRPGPASS---SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSR---- 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  771 lPPNNVTGKPGSAGiisSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG 850
Cdd:PHA03307   350 -SPSPSRPPPPADP---SSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGA 425

                          410
                   ....*....|....
gi 2462588888  851 PHVRYiqkPDNSPC 864
Cdd:PHA03307   426 FYARY---PLLTPS 436
DUF4813 pfam16072
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. ...
 525-655 2.86e-04

Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 345 and 672 amino acids in length.


Pssm-ID: 435117 [Multi-domain]  Cd Length: 288  Bit Score: 44.36  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  525 PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSY 604
Cdd:pfam16072  146 PGSVTTTSAGSGTTVINAGGQQPAAPAAPAYPVAPAAYPAQAPAAAPAPAPGAPQTPLAPLNPVAAAPAAAAGAAAAPVV 225

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462588888  605 TTPAPKDVlLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLE 655
Cdd:pfam16072  226 AAAAPAAA-APPPPAPAAPPADAAPPAPGGIICVPVRVPEPDPKDATKTIE 275
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 123-202 3.75e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 40.56  E-value: 3.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73


                   ..
gi 2462588888  201 VK 202
Cdd:cd00063     74 VR 75
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
481-694 8.19e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.71  E-value: 8.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  481 TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPK 560
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  561 QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPevSYTTPAPKDVLLPHKPYPEVSQSEPApletrgipfipm 640
Cdd:PRK12323   452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP--ADDDPPPWEELPPEFASPAPAQPDAA------------ 517

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  641 ispsPSQEELQTTLEETDQSTQEPFTTKIPRTT--ELAKTTQAPHRFYTTVRPRTS 694
Cdd:PRK12323   518 ----PAGWVAESIPDPATADPDDAFETLAPAPAaaPAPRAAAATEPVVAPRPPRAS 569
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 478-892 8.23e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 43.60  E-value: 8.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  478 MQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKIS--KSPEPTWTTPAPGKTQFISLKPKIPlSPEVTHT 555
Cdd:pfam03154  167 LQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSpaTSQPPNQTQSTAAPHTLIQQTPTLH-PQRLPSP 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  556 KPAPKQTPRAPPKPKTSPRPRIPQTQ--PVPKVPQRVTAKPKTSPSPevsyttpapkdvlLPHKPYPEVSQSEpaplETR 633
Cdd:pfam03154  246 HPPLQPMTQPPPPSQVSPQPLPQPSLhgQMPPMPHSLQTGPSHMQHP-------------VPPQPFPLTPQSS----QSQ 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  634 GIPFIPMISPSPSQEELQTTLEETDQSTQEPfttkiPRTTELAKttqAPHRFYTTVRPRTSDKPHI-RPVLNRTTTRPTR 712
Cdd:pfam03154  309 VPPGPSPAAPGQSQQRIHTPPSQSQLQSQQP-----PREQPLPP---APLSMPHIKPPPTTPIPQLpNPQSHKHPPHLSG 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  713 PKPSGMPSgngvgtgvkQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNnVTGKPGSAGIISSGPit 792
Cdd:pfam03154  381 PSPFQMNS---------NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPV-LTQSQSLPPPAASHP-- 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  793 tPPLRSTPRPTGTPLErietdiKQPTVPasgeelenitdfsSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSV-- 870
Cdd:pfam03154  449 -PTSGLHQVPSQSPFP------QHPFVP-------------GGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSGPVpa 508

                          410       420       430
                   ....*....|....*....|....*....|...
gi 2462588888  871 -----------KRFPKEEATEGNATSPPQNPPT 892
Cdd:pfam03154  509 avscplppvqiKEEALDEAEEPESPPPPPRSPS 541
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 448-714 8.24e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.52  E-value: 8.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  448 SRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT-PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPE 526
Cdd:PTZ00449   537 SKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKiPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPE 616

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  527 PTwTTPAPGKTQFISLKPKIPLSPevthTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRV----------TAKPKT 596
Cdd:PTZ00449   617 LL-DIPKSPKRPESPKSPKRPPPP----QRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFyddyldaaakSKETKT 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  597 SPSPEVSYTT-------PAPKDVLLPHKPYPEVSQSEPA-PLETRGIPFIPmiSPSPSQ-----EELQTTLEETDQSTQE 663
Cdd:PTZ00449   692 TVVLDESFESilketlpETPGTPFTTPRPLPPKLPRDEEfPFEPIGDPDAE--QPDDIEfftppEEERTFFHETPADTPL 769

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2462588888  664 P-FTTKIPRTTELAKTTQAPHRfyTTVRPRTSDKPHIRPvlnrTTTRPTRPK 714
Cdd:PTZ00449   770 PdILAEEFKEEDIHAETGEPDE--AMKRPDSPSEHEDKP----PGDHPSLPK 815
PHA03378 PHA03378
EBNA-3B; Provisional
 388-587 1.03e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.52  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  388 SSEKPWIVPTAKISEDSKVLQPqtATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTleQPRATLAPSETPfvp 467
Cdd:PHA03378   619 SAPRQWPMPLRPIPMRPLRMQP--ITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQPSPT--GANTMLPIQWAP--- 691

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  468 qkleifTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTwTTPAPGKTQFISLKPKIP 547
Cdd:PHA03378   692 ------GTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARP-PAAAPGRARPPAAAPGRA 764

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2462588888  548 LSPEVTHTKPAPKQTPRAPPKPKTSPRPRiPQTQPVPKVP 587
Cdd:PHA03378   765 RPPAAAPGAPTPQPPPQAPPAPQQRPRGA-PTPQPPPQAG 803
PRK11633 PRK11633
cell division protein DedD; Provisional
 522-610 1.18e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 41.91  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  522 SKSPEPTWTTPAPGKTQFISLKPKIPLSPEVThtkPAPKQTPRAPPKPKtsPRPRiPQTQPVPKVPQRVTAKPKTSPSPE 601
Cdd:PRK11633    65 TQPPEGAAEAVRAGDAAAPSLDPATVAPPNTP---VEPEPAPVEPPKPK--PVEK-PKPKPKPQQKVEAPPAPKPEPKPV 138


                   ....*....
gi 2462588888  602 VSyTTPAPK 610
Cdd:PRK11633   139 VE-EKAAPT 146
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 420-806 1.21e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.98  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  420 PTTSDEPEISDSYTATSDriLDSIPPKTSRTLEQPratLAPSETPF---VPQKLEIFTSPEMQPTTPAPQQTTSIPSTPK 496
Cdd:pfam05109  455 PTNLTAPASTGPTVSTAD--VTSPTPAGTTSGASP---VTPSPSPRdngTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  497 RRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTqfisLKPKIPLSPEVTHTKPAPKQTprAPPKPKTSPRPR 576
Cdd:pfam05109  530 PTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNAT----IPTLGKTSPTSAVTTPTPNAT--SPTVGETSPQAN 603

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  577 IP-QTQPVPKVPQRVTAKPKTSPSP----EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQ 651
Cdd:pfam05109  604 TTnHTLGGTSSTPVVTSPPKNATSAvttgQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQ 683

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  652 TTLEETdqSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRPTRPKPSGMPSGNGVGTGVKQA 731
Cdd:pfam05109  684 VTPAST--STHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGGKANST 761

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462588888  732 PRPSGADRNVSVDSTHPTkkPGTRRPPLPPRPTHPRRKPLPPNNvTGKPGSAGIISSGPITTPPLRSTPRPTGTP 806
Cdd:pfam05109  762 TGGKHTTGHGARTSTEPT--TDYGGDSTTPRTRYNATTYLPPST-SSKLRPRWTFTSPPVTTAQATVPVPPTSQP 833
PHA03369 PHA03369
capsid maturational protease; Provisional
 528-620 2.65e-03

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 41.91  E-value: 2.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  528 TWTTPAPGKTQFISLKPKIPLSPEvTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPkVPQRVTAKPKTSPSPEVSYTTP 607
Cdd:PHA03369   350 TASLTAPSRVLAAAAKVAVIAAPQ-THTGPADRQRPQRPDGIPYSVPARSPMTAYPP-VPQFCGDPGLVSPYNPQSPGTS 427

                           90
                   ....*....|...
gi 2462588888  608 APKDVLLPHKPYP 620
Cdd:PHA03369   428 YGPEPVGPVPPQP 440
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 522-610 2.76e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.76  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  522 SKSPEPTWTTPAPGKT-----QFISLKPKIPLSP-------EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 589
Cdd:COG3266    255 LKAPSQASSASAPATTslgeqQEVSLPPAVAAQPaaaaaaqPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKPVVTETAA 334

                           90       100
                   ....*....|....*....|.
gi 2462588888  590 VTAkpktsPSPEVSYTTPAPK 610
Cdd:COG3266    335 PAA-----PAPEAAAAAAAPA 350
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 335-751 3.24e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.48  E-value: 3.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  335 TTVTPETVPRST---KPTTSSALDVSETTLVLSKRTPETLQTIlipQFELPLSTLASSEKPWIVPTAKISEDSKVLQPQT 411
Cdd:pfam17823   84 TEVTAEHTPHGTdlsEPATREGAADGAASRALAAAASSSPSSA---AQSLPAAIAALPSEAFSAPRAAACRANASAAPRA 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  412 ATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPrATLAPSeTPFVPQKLEIFTsPEMQPTTPAPQQTTSI 491
Cdd:pfam17823  161 AIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAP-ATLTPA-RGISTAATATGH-PAAGTALAAVGNSSPA 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  492 PSTPKRRPRPKPPRTKPERTTSAGTIT--PKISKSPEPTWTTPAPGKTqfislkpkiplspevthtkpAPKQTPRAPPKP 569
Cdd:pfam17823  238 AGTVTAAVGTVTPAALATLAAAAGTVAsaAGTINMGDPHARRLSPAKH--------------------MPSDTMARNPAA 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  570 KTSPRPRIPQTQPVPKVPqrvtakpktspspeVSYTTPAPKdvllphkpypevsqsePAPLETRGIPFIPMISPSPSQee 649
Cdd:pfam17823  298 PMGAQAQGPIIQVSTDQP--------------VHNTAGEPT----------------PSPSNTTLEPNTPKSVASTNL-- 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  650 lqTTLEETDQSTQEPFTTKIPRttelakttqaphrfyttvrPRTSDKPHIRpvlnrtTTRPTrPKPSGMPSGNGV-GTGV 728
Cdd:pfam17823  346 --AVVTTTKAQAKEPSASPVPV-------------------LHTSMIPEVE------ATSPT-TQPSPLLPTQGAaGPGI 397

                          410       420
                   ....*....|....*....|...
gi 2462588888  729 KQAPRPSGADRNVSVDSTHPTKK 751
Cdd:pfam17823  398 LLAPEQVATEATAGTASAGPTPR 420
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
456-645 3.76e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  456 ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPG 535
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  536 KTqfislkpkiPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIP--QTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 613
Cdd:PRK12323   452 PA---------PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPaaAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWV 522

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2462588888  614 LPHKPYPEVSQSEP-----------APLETRGIPFIPMISPSP 645
Cdd:PRK12323   523 AESIPDPATADPDDafetlapapaaAPAPRAAAATEPVVAPRP 565
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 480-738 3.78e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.45  E-value: 3.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  480 PTTPAPQQTTSIPSTPKRRprpkpprtkpERTTSAGTITPKISKSPEPTWTTPAPGKTqfislkpkiPLSPEVTHTKPAP 559
Cdd:PLN03209   312 PLTPMEELLAKIPSQRVPP----------KESDAADGPKPVPTKPVTPEAPSPPIEEE---------PPQPKAVVPRPLS 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  560 KQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPApkdvllphkpypeVSQSEPAPLETRGI---- 635
Cdd:PLN03209   373 PYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASN-------------VPEVEPAQVEAKKTrpls 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  636 PFI------PMISPSPSQEE-LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPvlnrttt 708
Cdd:PLN03209   440 PYAryedlkPPTSPSPTAPTgVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSP------- 512

                          250       260       270
                   ....*....|....*....|....*....|.
gi 2462588888  709 RPTRPKPSGMP-SGNGVGTGVKQAPRPSGAD 738
Cdd:PLN03209   513 SPAAPVGKVAPsSTNEVVKVGNSAPPTALAD 543
Orthopox_A5L pfam06193
Orthopoxvirus A5L protein-like; This family includes several Orthopoxvirus A5L proteins. The ...
 509-674 4.14e-03

Orthopoxvirus A5L protein-like; This family includes several Orthopoxvirus A5L proteins. The vaccinia virus WR A5L open reading frame (corresponding to open reading frame A4L in vaccinia virus Copenhagen) encodes an immunodominant late protein found in the core of the vaccinia virion. The A5 protein appears to be required for the immature virion to form the brick-shaped intracellular mature virion.


Pssm-ID: 283778 [Multi-domain]  Cd Length: 216  Bit Score: 39.96  E-value: 4.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  509 ERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIP--LSPEVTHTKP-APKQTPRAPPKPKTSPRP-RIPQTQPVP 584
Cdd:pfam06193   13 EDATAKNSAYYSEEDDLDILGKKDEAGEIGFESQERQYQqqLIEQLAKDNMlAASRQPIQPLQPTIHITPiEIPTPAPTP 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  585 KVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRgIPFIPMISPSP---SQEELQTTLEETDQST 661
Cdd:pfam06193   93 KPRQQELGTPSTSCTQNSDASIACSTDIVTPPQPPIVATVCTPTPTDGR-ICTTADQNPNPgatIQKELDNMALKDLMSS 171

                          170
                   ....*....|...
gi 2462588888  662 QEPFTTKIPRTTE 674
Cdd:pfam06193  172 VEKDMCQLQAESE 184
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 512-613 5.14e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.95  E-value: 5.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  512 TSAGTITPKiSKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPR--APPKPKTSPRPRIPQTQPVPKVPQR 589
Cdd:PRK14950   364 PAPQPAKPT-AAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRpvAPPVPHTPESAPKLTRAAIPVDEKP 442

                           90       100
                   ....*....|....*....|....
gi 2462588888  590 VTAKPktSPSPEVSYTTPAPKDVL 613
Cdd:PRK14950   443 KYTPP--APPKEEEKALIADGDVL 464
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 518-649 6.30e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 6.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462588888  518 TPKISKSPEPTWTTPA-PGKTQFISLKPKIPLSPEVTHTKPAPKQTPR---APPKPKTSPRPRIPQTQPvPKVPQRVTAK 593
Cdd:PRK10263   754 QPQQPVAPQQQYQQPQqPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQPQYQQPQQ-PVAPQPQYQQ 832

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2462588888  594 PKTSPSpevsyttPAPKDVLLpHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 649
Cdd:PRK10263   833 PQQPVA-------PQPQDTLL-HPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVE 880
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH