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Conserved domains on  [gi|2217391135|ref|XP_047297818|]
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fatty-acid amide hydrolase 2 isoform X6 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GatA super family cl43040
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 45-219 1.98e-36

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


The actual alignment was detected with superfamily member COG0154:

Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 137.59  E-value: 1.98e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  45 TEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEkqeDEATLenkwPFL 124
Cdd:COG0154     1 MSDLAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAA---GEALG----PLA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 125 GVPLTVKEAFQLQG------------------------------------------------------------------ 138
Cdd:COG0154    74 GVPVAVKDLIDVAGlpttagskaladfvppydatvvarlraagavilgktnmpefamggstensaygptrnpwdpdrtpg 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 ----GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGaqelFLCTGPMCRYAEDLAPMLK 214
Cdd:COG0154   154 gssgGSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASS----LDQVGPLARTVADAALLLD 229


                  ....*
gi 2217391135 215 VMAGP 219
Cdd:COG0154   230 VLAGP 234
Amidase super family cl18951
Amidase;
151-356 2.47e-09

Amidase;


The actual alignment was detected with superfamily member PRK08310:

Pssm-ID: 450241 [Multi-domain]  Cd Length: 395  Bit Score: 58.46  E-value: 2.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 151 IGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvgaqELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV 230
Cdd:PRK08310  126 FALGTDTGGSVRAPASFCGLYGLRPTHGRISLEGVMPLA----PSFDTVGWFARDIALLERVGEVLLGDDAQEFPLTQRL 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 231 HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKEPVKFVDL----LGDHGKHV--SPLWElikwCLGLSVYTI-PSIGlAL 303
Cdd:PRK08310  202 LIPVDLFALLDPAVRAALEAALARLRPHLGPAKPASVPPLsldeWYEAFRVLqaAEAWE----THGAWISSGnPQLG-PG 276

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217391135 304 LEEKLRYS----NEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLT 356
Cdd:PRK08310  277 VADRFAAGaevtADQVEAARARRAAFARELAALLGPDAVLLLPTVPGAAPLRGAPFE 333
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 45-219 1.98e-36

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 137.59  E-value: 1.98e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  45 TEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEkqeDEATLenkwPFL 124
Cdd:COG0154     1 MSDLAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAA---GEALG----PLA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 125 GVPLTVKEAFQLQG------------------------------------------------------------------ 138
Cdd:COG0154    74 GVPVAVKDLIDVAGlpttagskaladfvppydatvvarlraagavilgktnmpefamggstensaygptrnpwdpdrtpg 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 ----GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGaqelFLCTGPMCRYAEDLAPMLK 214
Cdd:COG0154   154 gssgGSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASS----LDQVGPLARTVADAALLLD 229


                  ....*
gi 2217391135 215 VMAGP 219
Cdd:COG0154   230 VLAGP 234
PRK06170 PRK06170
amidase; Provisional
 55-220 5.16e-29

amidase; Provisional


Pssm-ID: 235723 [Multi-domain]  Cd Length: 490  Bit Score: 117.44  E-value: 5.16e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  55 QLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAeKQEDEatlenkwPFLGVPLTVKEAF 134
Cdd:PRK06170   16 ELAAALAAGEVSSVELTDLAIARIERHDGKINAIVVRDFDRARAAARAADAARA-RGERG-------PLLGIPVTVKESF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 135 Q--------------------------------------------LQ--------------------------GGEGCTL 144
Cdd:PRK06170   88 NvaglpttwgfpdlrdyvpaedavavarlkaagavilgktnvplgLQdwqsyneiygttnnpwdlartpggssGGSAAAL 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217391135 145 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPL---AVGAQELFLCTGPMCRYAEDLAPMLKVMAGPG 220
Cdd:PRK06170  168 AAGFGALSIGSDIGGSLRVPAHYCGVYAHKPTLGLVPLRGHIPPpapALPGQADLAVAGPMARSARDLALLLDVMAGPD 246
Amidase pfam01425
Amidase;
69-358 1.98e-26

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 109.31  E-value: 1.98e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  69 DVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDqklaekqEDEATLENKWPFLGVPLTVKEAF-------------- 134
Cdd:pfam01425   1 ELVEAFLDRIEAANPKLNAFVTVFFDEALAQAAAAD-------KQRAAGDPKGPLHGVPIAVKDNIdvkgvpttagskal 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 135 -------------QLQ-------------------------------------------GGEGCTLAAACSVIGVGSDIG 158
Cdd:pfam01425  74 enypapydatvveRLRkagavilgktnmdefamgsstensvfgptrnpwdlsrtpggssGGSAAAVAAGLVPLAIGTDTG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 159 GSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGaqelFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLD----------T 228
Cdd:pfam01425 154 GSIRIPASFCGLVGLKPTYGRVSRYGVVGYASS----LDQVGPLARSVEDAALLLRVISGYDPKDSTSLpppvpdyaepV 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 229 KVHLKDLKF-YWMEHdgGSFLMSKVDQDLIMTQK----KEPVKFVDLLGDHGKHVSPLWELIkWCLG----LSVYTIPSI 299
Cdd:pfam01425 230 KKSLKGLRIgVYRED--GYFDLDPEVRRAVEEALaqleALGHEVVEVDPPSLDYALPLYYLI-APAEassnLARYDGVPS 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 300 GLALLEEKL-------------------------RYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVP 354
Cdd:pfam01425 307 GPDDLSELYprtraeglgdevkrriilgnyalsaGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPRLGEP 386


                  ....
gi 2217391135 355 LTRP 358
Cdd:pfam01425 387 DDSP 390
PRK08310 PRK08310
amidase; Provisional
 151-356 2.47e-09

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 58.46  E-value: 2.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 151 IGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvgaqELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV 230
Cdd:PRK08310  126 FALGTDTGGSVRAPASFCGLYGLRPTHGRISLEGVMPLA----PSFDTVGWFARDIALLERVGEVLLGDDAQEFPLTQRL 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 231 HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKEPVKFVDL----LGDHGKHV--SPLWElikwCLGLSVYTI-PSIGlAL 303
Cdd:PRK08310  202 LIPVDLFALLDPAVRAALEAALARLRPHLGPAKPASVPPLsldeWYEAFRVLqaAEAWE----THGAWISSGnPQLG-PG 276

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217391135 304 LEEKLRYS----NEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLT 356
Cdd:PRK08310  277 VADRFAAGaevtADQVEAARARRAAFARELAALLGPDAVLLLPTVPGAAPLRGAPFE 333
 
Name Accession Description Interval E-value
GatA COG0154
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal ...
 45-219 1.98e-36

Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase [Translation, ribosomal structure and biogenesis]; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439924 [Multi-domain]  Cd Length: 468  Bit Score: 137.59  E-value: 1.98e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  45 TEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEkqeDEATLenkwPFL 124
Cdd:COG0154     1 MSDLAELSAAELAAALRAGEVSAVELVEAALARIEAVNPALNAFVTVDAERALAEARAADARRAA---GEALG----PLA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 125 GVPLTVKEAFQLQG------------------------------------------------------------------ 138
Cdd:COG0154    74 GVPVAVKDLIDVAGlpttagskaladfvppydatvvarlraagavilgktnmpefamggstensaygptrnpwdpdrtpg 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 ----GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGaqelFLCTGPMCRYAEDLAPMLK 214
Cdd:COG0154   154 gssgGSAAAVAAGLVPLALGSDTGGSIRIPAAFCGLVGLKPTYGRVSRYGVVPLASS----LDQVGPLARTVADAALLLD 229


                  ....*
gi 2217391135 215 VMAGP 219
Cdd:COG0154   230 VLAGP 234
PRK06170 PRK06170
amidase; Provisional
 55-220 5.16e-29

amidase; Provisional


Pssm-ID: 235723 [Multi-domain]  Cd Length: 490  Bit Score: 117.44  E-value: 5.16e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  55 QLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAeKQEDEatlenkwPFLGVPLTVKEAF 134
Cdd:PRK06170   16 ELAAALAAGEVSSVELTDLAIARIERHDGKINAIVVRDFDRARAAARAADAARA-RGERG-------PLLGIPVTVKESF 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 135 Q--------------------------------------------LQ--------------------------GGEGCTL 144
Cdd:PRK06170   88 NvaglpttwgfpdlrdyvpaedavavarlkaagavilgktnvplgLQdwqsyneiygttnnpwdlartpggssGGSAAAL 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217391135 145 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPL---AVGAQELFLCTGPMCRYAEDLAPMLKVMAGPG 220
Cdd:PRK06170  168 AAGFGALSIGSDIGGSLRVPAHYCGVYAHKPTLGLVPLRGHIPPpapALPGQADLAVAGPMARSARDLALLLDVMAGPD 246
Amidase pfam01425
Amidase;
69-358 1.98e-26

Amidase;


Pssm-ID: 396144 [Multi-domain]  Cd Length: 442  Bit Score: 109.31  E-value: 1.98e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  69 DVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDqklaekqEDEATLENKWPFLGVPLTVKEAF-------------- 134
Cdd:pfam01425   1 ELVEAFLDRIEAANPKLNAFVTVFFDEALAQAAAAD-------KQRAAGDPKGPLHGVPIAVKDNIdvkgvpttagskal 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 135 -------------QLQ-------------------------------------------GGEGCTLAAACSVIGVGSDIG 158
Cdd:pfam01425  74 enypapydatvveRLRkagavilgktnmdefamgsstensvfgptrnpwdlsrtpggssGGSAAAVAAGLVPLAIGTDTG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 159 GSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGaqelFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLD----------T 228
Cdd:pfam01425 154 GSIRIPASFCGLVGLKPTYGRVSRYGVVGYASS----LDQVGPLARSVEDAALLLRVISGYDPKDSTSLpppvpdyaepV 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 229 KVHLKDLKF-YWMEHdgGSFLMSKVDQDLIMTQK----KEPVKFVDLLGDHGKHVSPLWELIkWCLG----LSVYTIPSI 299
Cdd:pfam01425 230 KKSLKGLRIgVYRED--GYFDLDPEVRRAVEEALaqleALGHEVVEVDPPSLDYALPLYYLI-APAEassnLARYDGVPS 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 300 GLALLEEKL-------------------------RYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVP 354
Cdd:pfam01425 307 GPDDLSELYprtraeglgdevkrriilgnyalsaGYYDKYYLKAQKVRRLIRREFAGLFEELDVLLSPTAPTPAPRLGEP 386


                  ....
gi 2217391135 355 LTRP 358
Cdd:pfam01425 387 DDSP 390
PRK07487 PRK07487
amidase; Provisional
 45-222 6.96e-26

amidase; Provisional


Pssm-ID: 236029 [Multi-domain]  Cd Length: 469  Bit Score: 108.13  E-value: 6.96e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  45 TEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKqedeatlENKWPFL 124
Cdd:PRK07487    2 MQELWRLSAAELAAAVRSRDVSAREAAEAALARLDAVNPAINAVVDHRPEEALAQADAVDAARARG-------DDPGPLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 125 GVPLTVKE---------------------------------------------AFQLQ---------------------- 137
Cdd:PRK07487   75 GVPVTVKVnvdqagfattngvrlqkdliapadspvvdnlrkagaviigrtntpAFSYRwftdnplhgrtlnpwdpsltpg 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 138 ---GGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPN-KGQFP-LAVGAQeLFLCTGPMCRYAEDLAPM 212
Cdd:PRK07487  155 gssGGAAAAVAAGIGAIAHGTDIGGSIRYPAYACGVHGLRPTLGRVPAyNASSPeRPIGAQ-LMSVQGPLARTVADLRLA 233

                         250
                  ....*....|
gi 2217391135 213 LKVMAGPGIK 222
Cdd:PRK07487  234 LAAMAAPDPR 243
PRK07486 PRK07486
amidase; Provisional
 41-219 8.33e-23

amidase; Provisional


Pssm-ID: 236028 [Multi-domain]  Cd Length: 484  Bit Score: 99.32  E-value: 8.33e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  41 PRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEA-MKEAHAVDQKLAEK--------- 110
Cdd:PRK07486    2 ASPPPDPIVRLSAHALSRAIRRRQVSCVEVMRAYLAHIERVNPAVNAIVALRDRDAlLAEAAEKDAALARGeyrgwlhgm 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 111 ---------------------------QEDEATLE-------------NKWPF-LG------VPLTVKEAFQLQ------ 137
Cdd:PRK07486   82 pqapkdlaptkgirttlgspifadqvpQEDAIVVErmraagaifigktNTPEFgLGshtynpVYGATRNPYDPSrsaggs 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 138 -GGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKgqfPlavgAQELFL----CTGPMCRYAEDLAPM 212
Cdd:PRK07486  162 sGGAAAALALRMLPVADGSDMMGSLRNPAAFNNVYGFRPSQGRVPHG---P----GGDVFVqqlgTEGPMGRTVEDVALL 234


                  ....*..
gi 2217391135 213 LKVMAGP 219
Cdd:PRK07486  235 LAVQAGY 241
PRK06169 PRK06169
putative amidase; Provisional
 51-219 2.85e-15

putative amidase; Provisional


Pssm-ID: 180437 [Multi-domain]  Cd Length: 466  Bit Score: 76.99  E-value: 2.85e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  51 LSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQE-----------DEATLEN 119
Cdd:PRK06169    7 LTAVELLAAYRRGELSPVEATQAVLDRIDRRDPAVNAFCLVDAEGALAAARASEERWRRGEPcglldgvpvsiKDIFLTR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 120 KWP------------------------------FLG--------------VPL---------TVKEAFQLQGGEGCTLAA 146
Cdd:PRK06169   87 GWPtlrgsraidadgpwdvdapavarlreagavLLGktttpefgwkgvtdSPLygitrnpwdTRLTAGGSSGGAAAAVAL 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217391135 147 ACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPnkgQFPlaVGAQELFLCTGPMCRYAEDLAPMLKVMAGP 219
Cdd:PRK06169  167 GMGPLSVGTDGGGSVRIPASFCGTFGFKPTFGRVP---LYP--ASPFGTLAHVGPMTRTVADAALLLDVIARP 234
PRK07235 PRK07235
amidase; Provisional
 138-218 2.62e-14

amidase; Provisional


Pssm-ID: 235979 [Multi-domain]  Cd Length: 502  Bit Score: 73.89  E-value: 2.62e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 138 GGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLavgaqELFL-CTGPMCRYAEDLAPMLKVM 216
Cdd:PRK07235  173 SGSAALVAAGEVDMAIGGDQGGSIRIPSAWCGIYGMKPTHGLVPYTGAFPI-----ERTIdHLGPMTATVRDNALLLEVI 247


                  ..
gi 2217391135 217 AG 218
Cdd:PRK07235  248 AG 249
PRK07042 PRK07042
amidase; Provisional
 45-219 4.48e-14

amidase; Provisional


Pssm-ID: 235915 [Multi-domain]  Cd Length: 464  Bit Score: 73.08  E-value: 4.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  45 TEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAeKQEDEATLEnkwpfl 124
Cdd:PRK07042    1 MTALHDLSAVELLAGYRARSLSPVEVTEAVLAHIARWEPHLNALYAFDPEAARAAARASTARWA-KGEPLGPLD------ 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 125 GVPLTVKEAFQLQG------------------------------------------------------------------ 138
Cdd:PRK07042   74 GVPVTIKENIATRGvpvplgtaatdlppaaadappaarlreagavilakttmpdygmlssglssfhgltrnpwdldqnpg 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 ----GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKgqfPLAVGAqelflCTGPMCRYAEDLAPMLK 214
Cdd:PRK07042  154 gssaGAGAAAAAGYGPLHLGTDIGGSVRLPAGWCGIVGLKPSLGRIPID---PPYTGR-----CAGPMTRTVDDAALLMS 225


                  ....*
gi 2217391135 215 VMAGP 219
Cdd:PRK07042  226 VLSRP 230
PRK06529 PRK06529
amidase; Provisional
 56-181 6.91e-14

amidase; Provisional


Pssm-ID: 180608 [Multi-domain]  Cd Length: 482  Bit Score: 72.55  E-value: 6.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  56 LAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAhavdqklaeKQEDEATLenkwPFLGVPLTVKEAFQ 135
Cdd:PRK06529    9 MAQAVQQGQVTPLELVTQAIYKAKKLNPTLNAIVSERYEEALEEA---------KQRDFSGK----PFAGVPIFLKDLGQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 136 LQ-----------------------------------------------------------------------GGEGCTL 144
Cdd:PRK06529   76 ELkgqlstsgsrlfknyqatktdlyvkrledlgfiilgrsntpefgfknisdsslhgpvnlpfdnsrnaggssGGAAALV 155

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2217391135 145 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVP 181
Cdd:PRK06529  156 SSGIVALAAASDGGGSIRIPASFNGLIGLKPSRGRIP 192
PRK09201 PRK09201
AtzE family amidohydrolase;
51-219 7.72e-13

AtzE family amidohydrolase;


Pssm-ID: 236409 [Multi-domain]  Cd Length: 465  Bit Score: 69.23  E-value: 7.72e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  51 LSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKqedeatlENKWPFLGVPLTV 130
Cdd:PRK09201    7 LSAAEIAAAVRAGELSARAVAQATLARIARANPQLNAFTAVTAERALAEAARIDAARAAG-------EPLGPLAGVPFAV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 131 KEAFQLQ-----------------------------------------------------------------------GG 139
Cdd:PRK09201   80 KNLFDVAglttlagskinrdrppatrdatavrrleaagavlvgalnmdeyaygfttenshygatrnphdltriaggssGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 140 EGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLaVGAqelFLCTGPMCRYAEDLAPMLKVMAGP 219
Cdd:PRK09201  160 SAAAVAAGLVPFTLGSDTNGSIRVPASLCGIFGLKPTYGRLSRAGSFPF-VAS---LDHIGPFARSVADLALVYDVLQGP 235
PRK05962 PRK05962
amidase; Validated
 122-218 1.95e-11

amidase; Validated


Pssm-ID: 168315 [Multi-domain]  Cd Length: 424  Bit Score: 64.80  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 122 PFLGVPLTVKEAFQLQGGE----GCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELfl 197
Cdd:PRK05962  112 PHYGEPGNAIDPARIPGGSssgaAVSVAEGTSEIAIGSDTGGSVRIPAALNGLVGFKPTARRIPLEGAFPLSPSLDSI-- 189

                          90       100
                  ....*....|....*....|.
gi 2217391135 198 ctGPMCRYAEDLAPMLKVMAG 218
Cdd:PRK05962  190 --GPLARTVADCAAADAVMAG 208
PRK06102 PRK06102
amidase;
139-208 1.01e-10

amidase;


Pssm-ID: 235698 [Multi-domain]  Cd Length: 452  Bit Score: 62.74  E-value: 1.01e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELflctGPMCRYAED 208
Cdd:PRK06102  159 GSAVAVAAGLVPVAMGTDTGGSVRIPAAFNGLVGYKATRGRYSMDGVFPLAKSLDSL----GPLCRSVRD 224
PRK07056 PRK07056
amidase; Provisional
 141-218 1.77e-09

amidase; Provisional


Pssm-ID: 235921 [Multi-domain]  Cd Length: 454  Bit Score: 59.18  E-value: 1.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 141 GCTLAAACSV------IGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGaqelfLCT-GPMCRYAEDLAPML 213
Cdd:PRK07056  159 GSSSGAAVSVadgmaaAALGTDTGGSIRIPAALCGLTGFKPTARRVPLQGAVPLSTT-----LDSiGPLARSVACCALVD 233


                  ....*
gi 2217391135 214 KVMAG 218
Cdd:PRK07056  234 AVLAG 238
PRK08137 PRK08137
amidase; Provisional
 139-219 2.19e-09

amidase; Provisional


Pssm-ID: 236161 [Multi-domain]  Cd Length: 497  Bit Score: 58.63  E-value: 2.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvGAQElflCTGPMCRYAEDLAPMLKVMAG 218
Cdd:PRK08137  165 GSGAAVAAGLAAVAIGTETDGSITCPAAINGLVGLKPTVGLVSRDGIVPIS-HSQD---TAGPMTRTVADAAAVLTAIAG 240


                  .
gi 2217391135 219 P 219
Cdd:PRK08137  241 G 241
PRK08310 PRK08310
amidase; Provisional
 151-356 2.47e-09

amidase; Provisional


Pssm-ID: 181375 [Multi-domain]  Cd Length: 395  Bit Score: 58.46  E-value: 2.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 151 IGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvgaqELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV 230
Cdd:PRK08310  126 FALGTDTGGSVRAPASFCGLYGLRPTHGRISLEGVMPLA----PSFDTVGWFARDIALLERVGEVLLGDDAQEFPLTQRL 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 231 HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKEPVKFVDL----LGDHGKHV--SPLWElikwCLGLSVYTI-PSIGlAL 303
Cdd:PRK08310  202 LIPVDLFALLDPAVRAALEAALARLRPHLGPAKPASVPPLsldeWYEAFRVLqaAEAWE----THGAWISSGnPQLG-PG 276

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2217391135 304 LEEKLRYS----NEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLT 356
Cdd:PRK08310  277 VADRFAAGaevtADQVEAARARRAAFARELAALLGPDAVLLLPTVPGAAPLRGAPFE 333
PRK12470 PRK12470
amidase; Provisional
 57-230 1.01e-08

amidase; Provisional


Pssm-ID: 171524 [Multi-domain]  Cd Length: 462  Bit Score: 56.81  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  57 AKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQedeatlenKWPFLGVPLTVKEAFQL 136
Cdd:PRK12470   15 ARMLADGELTAPMLLEVYLQRIERLDSHLRAYRVVLFDRARAEAEAAQQRLDAGE--------RLPLLGVPIAIKDDVDV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 137 QG------GEGCT------------LAAACSVI----------------------------------------------- 151
Cdd:PRK12470   87 AGevttygSAGHGpaatsdaevvrrLRAAGAVIigktnvpelmimpfteslafgatrnpwdpnrtpggssggsaaavaag 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 152 ----GVGSDIGGSIRMPAFFNGIFGHKPSPGVV---PNKGQ-FPLAVgaqelflcTGPMCRYAEDLAPMLKVM------- 216
Cdd:PRK12470  167 lapvALGSDGGGSIRIPSTWCGLFGLKPQRDRIslePHDGAwQGLSV--------NGPIARSVMDAALLLDATttvpgpe 238

                         250       260
                  ....*....|....*....|..
gi 2217391135 217 ------AG--PGIKRLKLDTKV 230
Cdd:PRK12470  239 gefvaaAArePGRLRIALSTRV 260
PLN02722 PLN02722
indole-3-acetamide amidohydrolase
 139-350 1.11e-08

indole-3-acetamide amidohydrolase


Pssm-ID: 166363  Cd Length: 422  Bit Score: 56.44  E-value: 1.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvgaqELFLCTGPMCRYAEDLAPMLKV-MA 217
Cdd:PLN02722  115 GSAVAVGAKLVDFSLGTDTGGSVRVPASYCGIFGFRPSHGAVSTVGVIPMA----QSFDTVGWFARDPVILKRVGHVlLQ 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 218 GPGIKRLKLDTKVHLKD-LKFYWMEHDggsflmsKVDQDLIMTQKK-----EPVKFVDlLGDH-GKHVSPLWELIKWCLG 290
Cdd:PLN02722  191 QPDVNPIKPSQIIIAEDcFQLSSIPHD-------RLVQVLVKSVEKlfgggDIVKHVN-LGDYvEDKVPSLKHFMSKEIK 262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 291 LSVYTIPSI-----GLALLE----------------------------EKLRYSNEKYQKFKAVEESLRKELVDMLGDDG 337
Cdd:PLN02722  263 EQEYNIPSLaalssAMRLLQryefkinhgewitavkpefgpgiseriwEAVRTTEEKIDACQSVKTELRAALTTLLGEFG 342

                         250
                  ....*....|...
gi 2217391135 338 VFLYPSHPTVAPK 350
Cdd:PLN02722  343 VLVIPTVPGPPPK 355
PRK06828 PRK06828
amidase; Provisional
 139-219 2.23e-07

amidase; Provisional


Pssm-ID: 180715 [Multi-domain]  Cd Length: 491  Bit Score: 52.51  E-value: 2.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVgAQELflcTGPMCRYAEDLAPMLKVMAG 218
Cdd:PRK06828  175 GSAIAVAANFTVVSVGTETDGSILSPAVQNSVVGIKPTVGLISRRGIIPFTY-SQDT---AGPFARTVTDAAILLGSLTG 250


                  .
gi 2217391135 219 P 219
Cdd:PRK06828  251 V 251
PRK07869 PRK07869
amidase; Provisional
 56-225 2.80e-07

amidase; Provisional


Pssm-ID: 181154 [Multi-domain]  Cd Length: 468  Bit Score: 52.29  E-value: 2.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  56 LAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAhavdqklaekqedEATLENKWPFLGVPLTVK---- 131
Cdd:PRK07869   20 LAEAIRAGRVSAAEVVEAAIARAEAVNPALNALAYAAFDRARDRA-------------ARPGSQGGFFSGVPTFIKdnvd 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 132 ---------------------EAFQLQ---------------------------------------------GGEGCTLA 145
Cdd:PRK07869   87 vaglptmhgsdawtprpakadSDFARQflatglislgktqlpefgfsastehprlgpvrnpwntdysagassGGSAALVA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 146 AACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPG-VVPNKG--QFPLAVGAQelflctGPMCRYAEDLA------------ 210
Cdd:PRK07869  167 AGVVPIAHANDGGGSIRIPAACCGLVGLKPSRGrLPLDPElrRLPVNIVAN------GVLTRTVRDTAafyreaeryyrn 240

                         250
                  ....*....|....*...
gi 2217391135 211 ---PMLKVMAGPGIKRLK 225
Cdd:PRK07869  241 pklPPIGDVTGPGKQRLR 258
PRK06061 PRK06061
amidase; Provisional
 40-219 2.05e-06

amidase; Provisional


Pssm-ID: 235686 [Multi-domain]  Cd Length: 483  Bit Score: 49.31  E-value: 2.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135  40 TPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQedeatlen 119
Cdd:PRK06061    7 GAISGSGNDRLPGLTDQAYQLASGAVTSVELVRRSLRRIEASQPTLNAFRVVRAEAALAEAAEADRRRAAGD-------- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 120 KWPFLGVPLTVKE---------AFQLQG-----GEGCT----LAAACSVI------------------------------ 151
Cdd:PRK06061   79 RLPLLGVPIAVKDdvdvagvptAFGTAGevppaTADSEvvrrLRAAGAVIvgktntcelgqwpftsgpafghtrnpwsrd 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 152 ---------------------GVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNkgqFPLAvgaqELF---LCTGPMCRYAE 207
Cdd:PRK06061  159 htpggssggsaaavaaglvtaAIGSDGAGSVRIPAAWTHLVGIKPQRGRIST---WPLP----EAFnglTVNGPLARTVA 231

                         250
                  ....*....|..
gi 2217391135 208 DLAPMLKVMAGP 219
Cdd:PRK06061  232 DAALLLDAASGN 243
PRK06707 PRK06707
amidase; Provisional
 139-228 3.22e-06

amidase; Provisional


Pssm-ID: 235855 [Multi-domain]  Cd Length: 536  Bit Score: 49.14  E-value: 3.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 139 GEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvgaqELFLCTGPMCRYAEDLAPMLKVMAG 218
Cdd:PRK06707  230 GSATVVAADFAPLAVGTETTGSIVAPAAQQSVVGLRPSLGMVSRTGIIPLA----ETLDTAGPMARTVKDAATLFNAMIG 305

                          90
                  ....*....|
gi 2217391135 219 PGIKRLKLDT 228
Cdd:PRK06707  306 YDEKDVMTEK 315
PRK11910 PRK11910
amidase; Provisional
 141-208 4.92e-06

amidase; Provisional


Pssm-ID: 183377 [Multi-domain]  Cd Length: 615  Bit Score: 48.49  E-value: 4.92e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217391135 141 GCTLAAAC--SVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAvgaqELFLCTGPMCRYAED 208
Cdd:PRK11910  321 GSATAATSdfAAIAIGTETNGSIITPASAQSAVGYKPSQGLVNNKGIIPLS----SRFDTPGPLTRTVND 386
PRK08186 PRK08186
allophanate hydrolase; Provisional
 145-187 2.72e-05

allophanate hydrolase; Provisional


Pssm-ID: 236177 [Multi-domain]  Cd Length: 600  Bit Score: 45.99  E-value: 2.72e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2217391135 145 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFP 187
Cdd:PRK08186  160 ALGLVSFALGTDTAGSGRVPAAFNNIVGLKPTLGLLSTRGVVP 202
PRK07139 PRK07139
amidase; Provisional
 153-189 4.34e-05

amidase; Provisional


Pssm-ID: 235945 [Multi-domain]  Cd Length: 439  Bit Score: 45.42  E-value: 4.34e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2217391135 153 VGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLA 189
Cdd:PRK07139  136 IGSDTGDSVRLPASFIGKVGFKPSYGAISRYGLFAYA 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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