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Conserved domains on  [gi|1170859|sp|P43359|]
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PUTATIVE PSEUDOGENE: RecName: Full=Putative melanoma-associated antigen 5P; AltName: Full=Cancer/testis antigen 1.5; Short=CT1.5; AltName: Full=MAGE family member A5 pseudogene; AltName: Full=MAGE-5 antigen

Protein Classification

MAGE family protein( domain architecture ID 10575427)

MAGE (melanoma antigen-encoding gene) family protein containing the MAGE N-terminal domain, similar to human Melanoma-associated antigen 5 (MAGE-A5)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAGE_N pfam12440
Melanoma associated antigen family N terminal; This domain family is found in eukaryotes, and ...
 5-96 6.66e-29

Melanoma associated antigen family N terminal; This domain family is found in eukaryotes, and is typically between 82 and 96 amino acids in length. The family is found in association with pfam01454. This family is the N terminal of various melanoma associated antigens. These are tumour rejection antigens which are expressed on HLA-A1 of tumour cells and they are recognized by cytotoxic T lymphocytes (CTLs).


:

Pssm-ID: 463582 [Multi-domain]  Cd Length: 92  Bit Score: 100.45  E-value: 6.66e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1170859      5 QKSQHCKPEEGLDTQEEALGLVGVQAATTEEQEAVSSSSPLVPGTLGEVPAAGSPGPLKSPQGASAIPTAIDFTLWRQSI 84
Cdd:pfam12440   1 QKSKLRAREKRRQARSETQGLEGAQATAAEEEESPSSSSPLSGGTPESSPAAGSPSTPQSPQGAPSTTTAAAAVSSTRSD 80

                          90
                  ....*....|..
gi 1170859     85 KGSSNQEEEGPS 96
Cdd:pfam12440  81 EGASSQDEESPS 92
 
Name Accession Description Interval E-value
MAGE_N pfam12440
Melanoma associated antigen family N terminal; This domain family is found in eukaryotes, and ...
 5-96 6.66e-29

Melanoma associated antigen family N terminal; This domain family is found in eukaryotes, and is typically between 82 and 96 amino acids in length. The family is found in association with pfam01454. This family is the N terminal of various melanoma associated antigens. These are tumour rejection antigens which are expressed on HLA-A1 of tumour cells and they are recognized by cytotoxic T lymphocytes (CTLs).


Pssm-ID: 463582 [Multi-domain]  Cd Length: 92  Bit Score: 100.45  E-value: 6.66e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1170859      5 QKSQHCKPEEGLDTQEEALGLVGVQAATTEEQEAVSSSSPLVPGTLGEVPAAGSPGPLKSPQGASAIPTAIDFTLWRQSI 84
Cdd:pfam12440   1 QKSKLRAREKRRQARSETQGLEGAQATAAEEEESPSSSSPLSGGTPESSPAAGSPSTPQSPQGAPSTTTAAAAVSSTRSD 80

                          90
                  ....*....|..
gi 1170859     85 KGSSNQEEEGPS 96
Cdd:pfam12440  81 EGASSQDEESPS 92
 
Name Accession Description Interval E-value
MAGE_N pfam12440
Melanoma associated antigen family N terminal; This domain family is found in eukaryotes, and ...
 5-96 6.66e-29

Melanoma associated antigen family N terminal; This domain family is found in eukaryotes, and is typically between 82 and 96 amino acids in length. The family is found in association with pfam01454. This family is the N terminal of various melanoma associated antigens. These are tumour rejection antigens which are expressed on HLA-A1 of tumour cells and they are recognized by cytotoxic T lymphocytes (CTLs).


Pssm-ID: 463582 [Multi-domain]  Cd Length: 92  Bit Score: 100.45  E-value: 6.66e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1170859      5 QKSQHCKPEEGLDTQEEALGLVGVQAATTEEQEAVSSSSPLVPGTLGEVPAAGSPGPLKSPQGASAIPTAIDFTLWRQSI 84
Cdd:pfam12440   1 QKSKLRAREKRRQARSETQGLEGAQATAAEEEESPSSSSPLSGGTPESSPAAGSPSTPQSPQGAPSTTTAAAAVSSTRSD 80

                          90
                  ....*....|..
gi 1170859     85 KGSSNQEEEGPS 96
Cdd:pfam12440  81 EGASSQDEESPS 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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