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Conserved domains on  [gi|13375887|ref|NP_078921|]
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zinc finger matrin-type protein 4 isoform a [Homo sapiens]

Protein Classification

zinc finger protein( domain architecture ID 10583781)

zinc finger protein similar to Homo sapiens zinc finger matrin-type protein 4 (ZMAT4)

Gene Ontology:  GO:0008270|GO:0003677
PubMed:  22803940|12665246

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 142-176 1.11e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 41.08  E-value: 1.11e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 13375887    142 DSDRYCGLCAAWFNNPLMAQQHYDGKKHKKNAARV 176
Cdd:smart00451   1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 72-106 7.95e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.77  E-value: 7.95e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 13375887     72 DKNKCCTLCNMSFTSAVVADSHYQGKIHAKRLKLL 106
Cdd:smart00451   1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 198-222 2.78e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


:

Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.39  E-value: 2.78e-03
                          10        20
                  ....*....|....*....|....*
gi 13375887   198 YRCTICSVSLNSIEQYHAHLKGSKH 222
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 15-38 3.52e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


:

Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.01  E-value: 3.52e-03
                          10        20
                  ....*....|....*....|....
gi 13375887    15 YCKVCSAQLISESQRVAHYESRKH 38
Cdd:pfam12874   2 YCELCNVTFNSESQLKSHLQGKKH 25
 
Name Accession Description Interval E-value
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 142-176 1.11e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 41.08  E-value: 1.11e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 13375887    142 DSDRYCGLCAAWFNNPLMAQQHYDGKKHKKNAARV 176
Cdd:smart00451   1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 72-106 7.95e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.77  E-value: 7.95e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 13375887     72 DKNKCCTLCNMSFTSAVVADSHYQGKIHAKRLKLL 106
Cdd:smart00451   1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 77-99 1.19e-04

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 38.25  E-value: 1.19e-04
                          10        20
                  ....*....|....*....|...
gi 13375887    77 CTLCNMSFTSAVVADSHYQGKIH 99
Cdd:pfam12874   3 CELCNVTFNSESQLKSHLQGKKH 25
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 146-170 1.95e-04

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 37.53  E-value: 1.95e-04
                          10        20
                  ....*....|....*....|....*
gi 13375887   146 YCGLCAAWFNNPLMAQQHYDGKKHK 170
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 198-222 2.78e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.39  E-value: 2.78e-03
                          10        20
                  ....*....|....*....|....*
gi 13375887   198 YRCTICSVSLNSIEQYHAHLKGSKH 222
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 15-38 3.52e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.01  E-value: 3.52e-03
                          10        20
                  ....*....|....*....|....
gi 13375887    15 YCKVCSAQLISESQRVAHYESRKH 38
Cdd:pfam12874   2 YCELCNVTFNSESQLKSHLQGKKH 25
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 15-45 5.14e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 33.77  E-value: 5.14e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 13375887     15 YCKVCSAQLISESQRVAHYESRKHASKVRLY 45
Cdd:smart00451   5 YCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
 
Name Accession Description Interval E-value
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 142-176 1.11e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 41.08  E-value: 1.11e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 13375887    142 DSDRYCGLCAAWFNNPLMAQQHYDGKKHKKNAARV 176
Cdd:smart00451   1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 72-106 7.95e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 38.77  E-value: 7.95e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 13375887     72 DKNKCCTLCNMSFTSAVVADSHYQGKIHAKRLKLL 106
Cdd:smart00451   1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 77-99 1.19e-04

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 38.25  E-value: 1.19e-04
                          10        20
                  ....*....|....*....|...
gi 13375887    77 CTLCNMSFTSAVVADSHYQGKIH 99
Cdd:pfam12874   3 CELCNVTFNSESQLKSHLQGKKH 25
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 146-170 1.95e-04

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 37.53  E-value: 1.95e-04
                          10        20
                  ....*....|....*....|....*
gi 13375887   146 YCGLCAAWFNNPLMAQQHYDGKKHK 170
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 198-222 2.78e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.39  E-value: 2.78e-03
                          10        20
                  ....*....|....*....|....*
gi 13375887   198 YRCTICSVSLNSIEQYHAHLKGSKH 222
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 15-38 3.52e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 34.01  E-value: 3.52e-03
                          10        20
                  ....*....|....*....|....
gi 13375887    15 YCKVCSAQLISESQRVAHYESRKH 38
Cdd:pfam12874   2 YCELCNVTFNSESQLKSHLQGKKH 25
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 15-45 5.14e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 33.77  E-value: 5.14e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 13375887     15 YCKVCSAQLISESQRVAHYESRKHASKVRLY 45
Cdd:smart00451   5 YCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 146-169 5.65e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 33.24  E-value: 5.65e-03
                          10        20
                  ....*....|....*....|....
gi 13375887   146 YCGLCAAWFNNPLMAQQHYDGKKH 169
Cdd:pfam12874   2 YCELCNVTFNSESQLKSHLQGKKH 25
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 15-38 6.44e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 33.30  E-value: 6.44e-03
                          10        20
                  ....*....|....*....|....
gi 13375887    15 YCKVCSAQLISESQRVAHYESRKH 38
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKH 26
TUTase pfam19088
TUTase nucleotidyltransferase domain; This nucleotidyltransferase domain is found in TUTase ...
 198-229 7.75e-03

TUTase nucleotidyltransferase domain; This nucleotidyltransferase domain is found in TUTase enzymes. Terminal uridyltransferases (TUTases) execute 3' RNA uridylation across protists, fungi, metazoan and plant species.


Pssm-ID: 465974  Cd Length: 218  Bit Score: 36.26  E-value: 7.75e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 13375887   198 YRCTICSVSLNSIEQYHAHLKGSKHQTNLKNK 229
Cdd:pfam19088  51 YLCKLCSVHIENIQGAHKHIKEKRHKKNIMEK 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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