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Conserved domains on  [gi|5901946|ref|NP_008967|]
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endothelial cell-specific molecule 1 isoform a precursor [Homo sapiens]

Protein Classification

IB domain-containing protein( domain architecture ID 10638927)

IB domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 26-100 3.29e-12

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


:

Pssm-ID: 197525  Cd Length: 75  Bit Score: 59.02  E-value: 3.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5901946      26 VDCPqHCDSSECKSSP-RC-KRTVLDDCGCCRVCAAGRGETCyrtvsGMDGMKCGPGLRCQPSNG-EDPFGEEF---GIC 99
Cdd:smart00121   1 ARCP-PCDPARCPPCPpGCaELVRLDGCGCCPVCARQEGEPC-----GVYTPRCAPGLRCQPPPGeERPLRALLhgqGVC 74


                   .
gi 5901946     100 K 100
Cdd:smart00121  75 M 75
 
Name Accession Description Interval E-value
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 26-100 3.29e-12

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


Pssm-ID: 197525  Cd Length: 75  Bit Score: 59.02  E-value: 3.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5901946      26 VDCPqHCDSSECKSSP-RC-KRTVLDDCGCCRVCAAGRGETCyrtvsGMDGMKCGPGLRCQPSNG-EDPFGEEF---GIC 99
Cdd:smart00121   1 ARCP-PCDPARCPPCPpGCaELVRLDGCGCCPVCARQEGEPC-----GVYTPRCAPGLRCQPPPGeERPLRALLhgqGVC 74


                   .
gi 5901946     100 K 100
Cdd:smart00121  75 M 75
IGFBP pfam00219
Insulin-like growth factor binding protein;
28-83 6.87e-11

Insulin-like growth factor binding protein;


Pssm-ID: 459717  Cd Length: 53  Bit Score: 55.02  E-value: 6.87e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 5901946     28 CPQHCDSSEC-KSSPRCKR-TVLDDCGCCRVCAAGRGETCyrtvsGMDGMKCGPGLRC 83
Cdd:pfam00219   1 CPPPCDPERCpPPPPGCPAgVVLDGCGCCKVCARQEGEPC-----GVYTPPCGKGLRC 53
 
Name Accession Description Interval E-value
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 26-100 3.29e-12

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


Pssm-ID: 197525  Cd Length: 75  Bit Score: 59.02  E-value: 3.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5901946      26 VDCPqHCDSSECKSSP-RC-KRTVLDDCGCCRVCAAGRGETCyrtvsGMDGMKCGPGLRCQPSNG-EDPFGEEF---GIC 99
Cdd:smart00121   1 ARCP-PCDPARCPPCPpGCaELVRLDGCGCCPVCARQEGEPC-----GVYTPRCAPGLRCQPPPGeERPLRALLhgqGVC 74


                   .
gi 5901946     100 K 100
Cdd:smart00121  75 M 75
IGFBP pfam00219
Insulin-like growth factor binding protein;
28-83 6.87e-11

Insulin-like growth factor binding protein;


Pssm-ID: 459717  Cd Length: 53  Bit Score: 55.02  E-value: 6.87e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 5901946     28 CPQHCDSSEC-KSSPRCKR-TVLDDCGCCRVCAAGRGETCyrtvsGMDGMKCGPGLRC 83
Cdd:pfam00219   1 CPPPCDPERCpPPPPGCPAgVVLDGCGCCKVCARQEGEPC-----GVYTPPCGKGLRC 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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