|
Name |
Accession |
Description |
Interval |
E-value |
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1133-1342 |
1.84e-120 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
:
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 373.50 E-value: 1.84e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1133 PHPQDCAQHLMNGDTLSGVYPIFLNGElSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGL 1212
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1213 DNIHRITSQGRYELRVDMRDG-QEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCA 1291
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDWeGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 1292 MSYKGAWWYKNCHRTNLNGKYGESRH----SQGINWYHWKGHEFSIPFVEMKMRP 1342
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
566-919 |
1.57e-20 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 97.77 E-value: 1.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 566 PGSRYEVSVSAVRGTNESDSAT----TQFTTEIDAPKNLRVGSRTATSLDLEWD-NSEAEVQEYKVVYSTLAGEQYHEVl 640
Cdd:COG3401 201 PGTTYYYRVAATDTGGESAPSNevsvTTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKV- 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 641 vprGIGPTTRATLTDLVPGTEYGVGISAVMN----SQQSVPATMNARTEL-DSPRDLMVTASSETSISLIWTKASGP-ID 714
Cdd:COG3401 280 ---ATVTTTSYTDTGLTNGTTYYYRVTAVDAagneSAPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTASSDAdVT 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 715 HYRIT-FTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA--ERGRqQSLESTVDAFTGFRPISHLHFS-------H 784
Cdd:COG3401 357 GYNVYrSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGN-ESAPSEEVSATTASAASGESLTasvdavpL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 785 VTSSSVNITWSDPSPPADRLILNYSPRDEEeemmEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGI 864
Cdd:COG3401 436 TDVAGATAAASAASNPGVSAAVLADGGDTG----NAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSV 511
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFT 919
Cdd:COG3401 512 IGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLTTSASSSVSGAGL 566
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
203-231 |
7.71e-16 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
:
Pssm-ID: 376143 Cd Length: 29 Bit Score: 72.33 E-value: 7.71e-16
10 20
....*....|....*....|....*....
gi 157384973 203 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 231
Cdd:pfam18720 1 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
416-496 |
1.41e-12 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 64.36 E-value: 1.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFS---FDGWEISFIPKNNEGGVIAQ-VPSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNSGEPWNEItVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 157384973 492 RSPPT 496
Cdd:pfam00041 81 EGPPS 85
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
328-398 |
2.98e-12 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.59 E-value: 2.98e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 328 PPEDLRVAGISDRSIELEW----DGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAV 398
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1042-1127 |
2.78e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
:
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 60.97 E-value: 2.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1042 DPPANLTASEVTRQSALISWQPPR---AEIENYVLTYKSTDGSRKELI--VDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 1117 WS-SITSTAFTT 1127
Cdd:cd00063 82 ESpPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
507-583 |
5.91e-09 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.34 E-value: 5.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 507 PTQILVRDVSDTVAFVEWIPPR---AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
235-261 |
1.62e-08 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 51.53 E-value: 1.62e-08
10 20
....*....|....*....|....*..
gi 157384973 235 CPTDCSSRGLCVDGECVCEEPYTGEDC 261
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| C_rich_MXAN6577 super family |
cl49352 |
MXAN_6577-like cysteine-rich domain; |
207-312 |
1.13e-07 |
|
MXAN_6577-like cysteine-rich domain;
The actual alignment was detected with superfamily member NF041328:
Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 52.45 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 207 GCSSRG-VCVDGQCICdseysGDDCSELR--------CPTDCSSRGLCVDGECVCEEPYT--GEDCRELRC-PGDCSGKG 274
Cdd:NF041328 13 GCPEPGaVCPEGLSVC-----GGACVDLRsdpsncgaCGVACGAGQTCVAGACGCGPGTVacGGACVDTASdPAHCGACG 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 157384973 275 R-------CANGTCL--CEEGYVgeDCGQR------------QCLNACSGRGQCEEGLC 312
Cdd:NF041328 88 AacapgqvCEGGACReaCSEGLT--RCGGAcvdlatdplhcgACGVACDPGESCRGGAC 144
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
954-1026 |
7.45e-07 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.18 E-value: 7.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 954 DNPVDLIATNITPTEALLQWKAPV---GEVENYVIvltHFAVAGE-----TILVDGVSEEFRLVDLLPSTHYTATMYATN 1025
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEV---EYRPKNSgepwnEITVPGTTTSVTLTGLKPGTEYEVRVQAVN 77
|
.
gi 157384973 1026 G 1026
Cdd:pfam00041 78 G 78
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1133-1342 |
1.84e-120 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 373.50 E-value: 1.84e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1133 PHPQDCAQHLMNGDTLSGVYPIFLNGElSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGL 1212
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1213 DNIHRITSQGRYELRVDMRDG-QEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCA 1291
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDWeGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 1292 MSYKGAWWYKNCHRTNLNGKYGESRH----SQGINWYHWKGHEFSIPFVEMKMRP 1342
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1134-1343 |
2.75e-120 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 372.77 E-value: 2.75e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1134 HPQDCAQHLMNGDTLSGVYPIFLNGElSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLD 1213
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGS-SRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1214 NIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGD-SLSYHQGRPFSTEDRDNDVAVTNCA 1291
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 157384973 1292 MSYKGAWWYKNCHRTNLNGKYG-ESRHSQGINWYHWKGHEFSIPFVEMKMRPY 1343
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRPL 212
|
|
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1135-1343 |
1.00e-97 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 311.76 E-value: 1.00e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQkLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVE-DEFWLGLD 1213
Cdd:pfam00147 2 GRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSpGEFWLGND 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1214 NIHRITSQGRYELRVDMRDGQ-EAAFASYDRFSVEDSRNLYKLRIGSYNGTAGD-------SLSYHQGRPFSTEDRDNDV 1285
Cdd:pfam00147 81 KIHLLTKQGPYVLRIDLEDWNgETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDNDS 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157384973 1286 AVTNCAMSYKGAWWYKNCHRTNLNGKY--GESRHSQ-GINWYHWKGHEFSIPFVEMKMRPY 1343
Cdd:pfam00147 161 PDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
566-919 |
1.57e-20 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 97.77 E-value: 1.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 566 PGSRYEVSVSAVRGTNESDSAT----TQFTTEIDAPKNLRVGSRTATSLDLEWD-NSEAEVQEYKVVYSTLAGEQYHEVl 640
Cdd:COG3401 201 PGTTYYYRVAATDTGGESAPSNevsvTTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKV- 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 641 vprGIGPTTRATLTDLVPGTEYGVGISAVMN----SQQSVPATMNARTEL-DSPRDLMVTASSETSISLIWTKASGP-ID 714
Cdd:COG3401 280 ---ATVTTTSYTDTGLTNGTTYYYRVTAVDAagneSAPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTASSDAdVT 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 715 HYRIT-FTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA--ERGRqQSLESTVDAFTGFRPISHLHFS-------H 784
Cdd:COG3401 357 GYNVYrSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGN-ESAPSEEVSATTASAASGESLTasvdavpL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 785 VTSSSVNITWSDPSPPADRLILNYSPRDEEeemmEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGI 864
Cdd:COG3401 436 TDVAGATAAASAASNPGVSAAVLADGGDTG----NAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSV 511
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFT 919
Cdd:COG3401 512 IGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLTTSASSSVSGAGL 566
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
203-231 |
7.71e-16 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 72.33 E-value: 7.71e-16
10 20
....*....|....*....|....*....
gi 157384973 203 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 231
Cdd:pfam18720 1 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
687-766 |
4.65e-15 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 71.68 E-value: 4.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 687 DSPRDLMVTASSETSISLIWTKA---SGPIDHYRITFTP--SSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQ 761
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 157384973 762 QSLES 766
Cdd:pfam00041 81 EGPPS 85
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
865-943 |
9.11e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 68.29 E-value: 9.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPV---ASFDYYRVSYRPTQVGR-LDSSVVPNTVTEFTITRLNPATEYEISLNSVRGRE 940
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
...
gi 157384973 941 ESE 943
Cdd:cd00063 82 ESP 84
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
687-763 |
2.43e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 66.48 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 687 DSPRDLMVTASSETSISLIWTKAS-----GPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQ 761
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 157384973 762 QS 763
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
416-496 |
1.41e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 64.36 E-value: 1.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFS---FDGWEISFIPKNNEGGVIAQ-VPSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNSGEPWNEItVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 157384973 492 RSPPT 496
Cdd:pfam00041 81 EGPPS 85
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
328-398 |
2.98e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.59 E-value: 2.98e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 328 PPEDLRVAGISDRSIELEW----DGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAV 398
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
328-413 |
5.61e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 63.28 E-value: 5.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 328 PPEDLRVAGISDRSIELEWDGP----MAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNIL 403
Cdd:cd00063 3 PPTNLRVTDVTSTSVTLSWTPPeddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82
|
90
....*....|
gi 157384973 404 SLPITAKVAT 413
Cdd:cd00063 83 SPPSESVTVT 92
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1042-1127 |
2.78e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 60.97 E-value: 2.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1042 DPPANLTASEVTRQSALISWQPPR---AEIENYVLTYKSTDGSRKELI--VDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 1117 WS-SITSTAFTT 1127
Cdd:cd00063 82 ESpPSESVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
327-515 |
6.47e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 66.95 E-value: 6.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 327 APPEDLRVAGISDRSIELEWDGP--MAVTEYVISYQPTALGGLQLQQRVPGdwSGVTITELEPGLTYNISVYAVISN--- 401
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWDPVteSDATGYRVYRSNSGDGPFTKVATVTT--TSYTDTGLTNGTTYYYRVTAVDAAgne 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 402 -ILSLPITAKVATHL-STPQGLQFKTITETTVEVQWEPfsfSFDGWEISFI--PKNNEGG---VIAQVPSDvTSFNQTGL 474
Cdd:COG3401 312 sAPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTA---SSDADVTGYNvyRSTSGGGtytKIAETVTT-TSYTDTGL 387
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 157384973 475 KPGEEYIVNVVAL----KEQARSPPTSASVSTVIDGPTQILVRDV 515
Cdd:COG3401 388 TPGTTYYYKVTAVdaagNESAPSEEVSATTASAASGESLTASVDA 432
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1042-1111 |
9.54e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 59.17 E-value: 9.54e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 1042 DPPANLTASEVTRQSALISWQPP-----RAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1042-1118 |
5.20e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 5.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1042 DPPANLTASEVTRQSALISWQPPR---AEIENYVLTYKSTDGSR--KELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
..
gi 157384973 1117 WS 1118
Cdd:pfam00041 81 EG 82
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
416-503 |
5.48e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 57.51 E-value: 5.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFS---FDGWEISFIPKNNEGGVIAQV-PSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 492 RSPPTSASVSTV 503
Cdd:cd00063 82 ESPPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
507-583 |
5.91e-09 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.34 E-value: 5.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 507 PTQILVRDVSDTVAFVEWIPPR---AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
328-398 |
1.16e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.39 E-value: 1.16e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 328 PPEDLRVAGISDRSIELEWDGP--MAVTEYVISYQPTALGGLQLQQRVPGDWSG--VTITELEPGLTYNISVYAV 398
Cdd:smart00060 3 PPSNLRVTDVTSTSVTLSWEPPpdDGITGYIVGYRVEYREEGSEWKEVNVTPSStsYTLTGLKPGTEYEFRVRAV 77
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
235-261 |
1.62e-08 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 51.53 E-value: 1.62e-08
10 20
....*....|....*....|....*..
gi 157384973 235 CPTDCSSRGLCVDGECVCEEPYTGEDC 261
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
505-592 |
5.47e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 5.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 505 DGPTQILVRDVSDTVAFVEWIPPRAKVDFIL---LKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTN 581
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEDDGGPITgyvVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 582 ESD-SATTQFTT 592
Cdd:cd00063 82 ESPpSESVTVTT 93
|
|
| C_rich_MXAN6577 |
NF041328 |
MXAN_6577-like cysteine-rich domain; |
207-312 |
1.13e-07 |
|
MXAN_6577-like cysteine-rich domain;
Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 52.45 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 207 GCSSRG-VCVDGQCICdseysGDDCSELR--------CPTDCSSRGLCVDGECVCEEPYT--GEDCRELRC-PGDCSGKG 274
Cdd:NF041328 13 GCPEPGaVCPEGLSVC-----GGACVDLRsdpsncgaCGVACGAGQTCVAGACGCGPGTVacGGACVDTASdPAHCGACG 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 157384973 275 R-------CANGTCL--CEEGYVgeDCGQR------------QCLNACSGRGQCEEGLC 312
Cdd:NF041328 88 AacapgqvCEGGACReaCSEGLT--RCGGAcvdlatdplhcgACGVACDPGESCRGGAC 144
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1138-1177 |
1.45e-07 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 49.10 E-value: 1.45e-07
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 157384973 1138 CAQ-HLMNGDTLSGVYPIFLNGE-LSQKLQVYCDMTTDGGGW 1177
Cdd:NF040941 2 CWEiLQAGPSAPSGVYWIDPDGMgGLAPFQVYCDMTTDGGGW 43
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
416-486 |
2.21e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 2.21e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFSFDGW-EISFIPKNNEGG---VIAQVPSDVTSFNQTGLKPGEEYIVNVVA 486
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITGyIVGYRVEYREEGsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
954-1026 |
7.45e-07 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.18 E-value: 7.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 954 DNPVDLIATNITPTEALLQWKAPV---GEVENYVIvltHFAVAGE-----TILVDGVSEEFRLVDLLPSTHYTATMYATN 1025
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEV---EYRPKNSgepwnEITVPGTTTSVTLTGLKPGTEYEVRVQAVN 77
|
.
gi 157384973 1026 G 1026
Cdd:pfam00041 78 G 78
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
954-1026 |
1.51e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 47.22 E-value: 1.51e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157384973 954 DNPVDLIATNITPTEALLQWKAP-----VGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNG 1026
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
954-1035 |
2.85e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.72 E-value: 2.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 954 DNPVDLIATNITPTEALLQWKAPV---GEVENYVIVLTHFAVAG-ETILVDGVSE-EFRLVDLLPSTHYTATMYATNG-- 1026
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwKEVEVTPGSEtSYTLTGLKPGTEYEFRVRAVNGgg 81
|
90
....*....|..
gi 157384973 1027 ---PLTSGTIST 1035
Cdd:cd00063 82 espPSESVTVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
505-583 |
9.80e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.91 E-value: 9.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 505 DGPTQILVRDVSDTVAFVEWIPP-RAKVDFILLKYGLVGGEGGRTTFRL--QPPLSQYSVQALRPGSRYEVSVSAVRGTN 581
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpDDGITGYIVGYRVEYREEGSEWKEVnvTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 157384973 582 ES 583
Cdd:smart00060 82 EG 83
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
300-323 |
6.02e-05 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 41.18 E-value: 6.02e-05
10 20
....*....|....*....|....*.
gi 157384973 300 ACSGRGQCE--EGLCVCEEGYQGPDC 323
Cdd:pfam07974 1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1133-1342 |
1.84e-120 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 373.50 E-value: 1.84e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1133 PHPQDCAQHLMNGDTLSGVYPIFLNGElSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGL 1212
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1213 DNIHRITSQGRYELRVDMRDG-QEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCA 1291
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDWeGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 1292 MSYKGAWWYKNCHRTNLNGKYGESRH----SQGINWYHWKGHEFSIPFVEMKMRP 1342
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1134-1343 |
2.75e-120 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 372.77 E-value: 2.75e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1134 HPQDCAQHLMNGDTLSGVYPIFLNGElSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLD 1213
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGS-SRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1214 NIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGD-SLSYHQGRPFSTEDRDNDVAVTNCA 1291
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 157384973 1292 MSYKGAWWYKNCHRTNLNGKYG-ESRHSQGINWYHWKGHEFSIPFVEMKMRPY 1343
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRPL 212
|
|
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1135-1343 |
1.00e-97 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 311.76 E-value: 1.00e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQkLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVE-DEFWLGLD 1213
Cdd:pfam00147 2 GRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSpGEFWLGND 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1214 NIHRITSQGRYELRVDMRDGQ-EAAFASYDRFSVEDSRNLYKLRIGSYNGTAGD-------SLSYHQGRPFSTEDRDNDV 1285
Cdd:pfam00147 81 KIHLLTKQGPYVLRIDLEDWNgETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDNDS 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157384973 1286 AVTNCAMSYKGAWWYKNCHRTNLNGKY--GESRHSQ-GINWYHWKGHEFSIPFVEMKMRPY 1343
Cdd:pfam00147 161 PDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
566-919 |
1.57e-20 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 97.77 E-value: 1.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 566 PGSRYEVSVSAVRGTNESDSAT----TQFTTEIDAPKNLRVGSRTATSLDLEWD-NSEAEVQEYKVVYSTLAGEQYHEVl 640
Cdd:COG3401 201 PGTTYYYRVAATDTGGESAPSNevsvTTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKV- 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 641 vprGIGPTTRATLTDLVPGTEYGVGISAVMN----SQQSVPATMNARTEL-DSPRDLMVTASSETSISLIWTKASGP-ID 714
Cdd:COG3401 280 ---ATVTTTSYTDTGLTNGTTYYYRVTAVDAagneSAPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTASSDAdVT 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 715 HYRIT-FTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA--ERGRqQSLESTVDAFTGFRPISHLHFS-------H 784
Cdd:COG3401 357 GYNVYrSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGN-ESAPSEEVSATTASAASGESLTasvdavpL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 785 VTSSSVNITWSDPSPPADRLILNYSPRDEEeemmEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGI 864
Cdd:COG3401 436 TDVAGATAAASAASNPGVSAAVLADGGDTG----NAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSV 511
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFT 919
Cdd:COG3401 512 IGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSLTTSASSSVSGAGL 566
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
203-231 |
7.71e-16 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 72.33 E-value: 7.71e-16
10 20
....*....|....*....|....*....
gi 157384973 203 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 231
Cdd:pfam18720 1 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
687-766 |
4.65e-15 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 71.68 E-value: 4.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 687 DSPRDLMVTASSETSISLIWTKA---SGPIDHYRITFTP--SSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQ 761
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 157384973 762 QSLES 766
Cdd:pfam00041 81 EGPPS 85
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
865-944 |
1.19e-14 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 70.52 E-value: 1.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPV---ASFDYYRVSYRPTQVGRLDSSV-VPNTVTEFTITRLNPATEYEISLNSVRGRE 940
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEItVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 157384973 941 ESER 944
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
865-943 |
9.11e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 68.29 E-value: 9.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPV---ASFDYYRVSYRPTQVGR-LDSSVVPNTVTEFTITRLNPATEYEISLNSVRGRE 940
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
...
gi 157384973 941 ESE 943
Cdd:cd00063 82 ESP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
687-772 |
1.34e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 67.91 E-value: 1.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 687 DSPRDLMVTASSETSISLIWTKAS---GPIDHYRITFTPSSGIASEV--TVPKDRTSYTLTDLEPGAEYIISVTAERGRQ 761
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEveVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 157384973 762 QSLESTVDAFT 772
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
687-763 |
2.43e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 66.48 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 687 DSPRDLMVTASSETSISLIWTKAS-----GPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQ 761
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPddgitGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 157384973 762 QS 763
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
416-496 |
1.41e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 64.36 E-value: 1.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFS---FDGWEISFIPKNNEGGVIAQ-VPSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNSGEPWNEItVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....*
gi 157384973 492 RSPPT 496
Cdd:pfam00041 81 EGPPS 85
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
328-398 |
2.98e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.59 E-value: 2.98e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 328 PPEDLRVAGISDRSIELEW----DGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAV 398
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
328-413 |
5.61e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 63.28 E-value: 5.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 328 PPEDLRVAGISDRSIELEWDGP----MAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNIL 403
Cdd:cd00063 3 PPTNLRVTDVTSTSVTLSWTPPeddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82
|
90
....*....|
gi 157384973 404 SLPITAKVAT 413
Cdd:cd00063 83 SPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
865-942 |
9.53e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 62.25 E-value: 9.53e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 865 DPPKDITISNVTKDSVMVSWSPPV-ASFDYYRVSYRPTQVGRLDSSV---VPNTVTEFTITRLNPATEYEISLNSVRGRE 940
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSEWKevnVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 157384973 941 ES 942
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
776-855 |
2.08e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 776 PISHLHFSHVTSSSVNITWSdPSPPADRLILNYS----PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSWT-PPPDGNGPITGYEveyrPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 157384973 852 TSEP 855
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1042-1127 |
2.78e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 60.97 E-value: 2.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1042 DPPANLTASEVTRQSALISWQPPR---AEIENYVLTYKSTDGSRKELI--VDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 1117 WS-SITSTAFTT 1127
Cdd:cd00063 82 ESpPSESVTVTT 93
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
595-679 |
6.00e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 60.20 E-value: 6.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 595 DAPKNLRVGSRTATSLDLEWD---NSEAEVQEYKVVYSTLAGEQYHEVLVPRGigPTTRATLTDLVPGTEYGVGISAVMN 671
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTppeDDGGPITGYVVEYREKGSGDWKEVEVTPG--SETSYTLTGLKPGTEYEFRVRAVNG 79
|
....*...
gi 157384973 672 SQQSVPAT 679
Cdd:cd00063 80 GGESPPSE 87
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
327-515 |
6.47e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 66.95 E-value: 6.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 327 APPEDLRVAGISDRSIELEWDGP--MAVTEYVISYQPTALGGLQLQQRVPGdwSGVTITELEPGLTYNISVYAVISN--- 401
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWDPVteSDATGYRVYRSNSGDGPFTKVATVTT--TSYTDTGLTNGTTYYYRVTAVDAAgne 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 402 -ILSLPITAKVATHL-STPQGLQFKTITETTVEVQWEPfsfSFDGWEISFI--PKNNEGG---VIAQVPSDvTSFNQTGL 474
Cdd:COG3401 312 sAPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTA---SSDADVTGYNvyRSTSGGGtytKIAETVTT-TSYTDTGL 387
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 157384973 475 KPGEEYIVNVVAL----KEQARSPPTSASVSTVIDGPTQILVRDV 515
Cdd:COG3401 388 TPGTTYYYKVTAVdaagNESAPSEEVSATTASAASGESLTASVDA 432
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1042-1111 |
9.54e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 59.17 E-value: 9.54e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 1042 DPPANLTASEVTRQSALISWQPP-----RAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1042-1118 |
5.20e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.42 E-value: 5.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1042 DPPANLTASEVTRQSALISWQPPR---AEIENYVLTYKSTDGSR--KELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
..
gi 157384973 1117 WS 1118
Cdd:pfam00041 81 EG 82
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
416-503 |
5.48e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 57.51 E-value: 5.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFS---FDGWEISFIPKNNEGGVIAQV-PSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 492 RSPPTSASVSTV 503
Cdd:cd00063 82 ESPPSESVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
595-669 |
9.91e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 56.27 E-value: 9.91e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157384973 595 DAPKNLRVGSRTATSLDLEW---DNSEAEVQEYKVVYSTLAGEQY-HEVLVPRgigPTTRATLTDLVPGTEYGVGISAV 669
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPwNEITVPG---TTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
776-862 |
2.79e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 55.58 E-value: 2.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 776 PISHLHFSHVTSSSVNITWSDPSPPADRL---ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVT 852
Cdd:cd00063 3 PPTNLRVTDVTSTSVTLSWTPPEDDGGPItgyVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82
|
90
....*....|.
gi 157384973 853 SEPI-VGSITT 862
Cdd:cd00063 83 SPPSeSVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
507-583 |
5.91e-09 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 54.34 E-value: 5.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 507 PTQILVRDVSDTVAFVEWIPPR---AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
776-847 |
7.28e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 7.28e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 776 PISHLHFSHVTSSSVNITWSDPSPPADRL-ILNYSP--RDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAV 847
Cdd:smart00060 3 PPSNLRVTDVTSTSVTLSWEPPPDDGITGyIVGYRVeyREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
595-669 |
7.72e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.77 E-value: 7.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 595 DAPKNLRVGSRTATSLDLEW-----DNSEAEVQEYKVVYSTlAGEQYHEVLVPrgiGPTTRATLTDLVPGTEYGVGISAV 669
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWepppdDGITGYIVGYRVEYRE-EGSEWKEVNVT---PSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
328-398 |
1.16e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 53.39 E-value: 1.16e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 328 PPEDLRVAGISDRSIELEWDGP--MAVTEYVISYQPTALGGLQLQQRVPGDWSG--VTITELEPGLTYNISVYAV 398
Cdd:smart00060 3 PPSNLRVTDVTSTSVTLSWEPPpdDGITGYIVGYRVEYREEGSEWKEVNVTPSStsYTLTGLKPGTEYEFRVRAV 77
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
235-261 |
1.62e-08 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 51.53 E-value: 1.62e-08
10 20
....*....|....*....|....*..
gi 157384973 235 CPTDCSSRGLCVDGECVCEEPYTGEDC 261
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
505-592 |
5.47e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 5.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 505 DGPTQILVRDVSDTVAFVEWIPPRAKVDFIL---LKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTN 581
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEDDGGPITgyvVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 157384973 582 ESD-SATTQFTT 592
Cdd:cd00063 82 ESPpSESVTVTT 93
|
|
| C_rich_MXAN6577 |
NF041328 |
MXAN_6577-like cysteine-rich domain; |
207-312 |
1.13e-07 |
|
MXAN_6577-like cysteine-rich domain;
Pssm-ID: 469225 [Multi-domain] Cd Length: 145 Bit Score: 52.45 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 207 GCSSRG-VCVDGQCICdseysGDDCSELR--------CPTDCSSRGLCVDGECVCEEPYT--GEDCRELRC-PGDCSGKG 274
Cdd:NF041328 13 GCPEPGaVCPEGLSVC-----GGACVDLRsdpsncgaCGVACGAGQTCVAGACGCGPGTVacGGACVDTASdPAHCGACG 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 157384973 275 R-------CANGTCL--CEEGYVgeDCGQR------------QCLNACSGRGQCEEGLC 312
Cdd:NF041328 88 AacapgqvCEGGACReaCSEGLT--RCGGAcvdlatdplhcgACGVACDPGESCRGGAC 144
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1138-1177 |
1.45e-07 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 49.10 E-value: 1.45e-07
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 157384973 1138 CAQ-HLMNGDTLSGVYPIFLNGE-LSQKLQVYCDMTTDGGGW 1177
Cdd:NF040941 2 CWEiLQAGPSAPSGVYWIDPDGMgGLAPFQVYCDMTTDGGGW 43
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
416-486 |
2.21e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 2.21e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157384973 416 STPQGLQFKTITETTVEVQWEPFSFSFDGW-EISFIPKNNEGG---VIAQVPSDVTSFNQTGLKPGEEYIVNVVA 486
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITGyIVGYRVEYREEGsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
954-1026 |
7.45e-07 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 48.18 E-value: 7.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 954 DNPVDLIATNITPTEALLQWKAPV---GEVENYVIvltHFAVAGE-----TILVDGVSEEFRLVDLLPSTHYTATMYATN 1025
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEV---EYRPKNSgepwnEITVPGTTTSVTLTGLKPGTEYEVRVQAVN 77
|
.
gi 157384973 1026 G 1026
Cdd:pfam00041 78 G 78
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
954-1026 |
1.51e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 47.22 E-value: 1.51e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157384973 954 DNPVDLIATNITPTEALLQWKAP-----VGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNG 1026
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
954-1035 |
2.85e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.72 E-value: 2.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 954 DNPVDLIATNITPTEALLQWKAPV---GEVENYVIVLTHFAVAG-ETILVDGVSE-EFRLVDLLPSTHYTATMYATNG-- 1026
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDwKEVEVTPGSEtSYTLTGLKPGTEYEFRVRAVNGgg 81
|
90
....*....|..
gi 157384973 1027 ---PLTSGTIST 1035
Cdd:cd00063 82 espPSESVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
838-1106 |
4.27e-06 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 51.16 E-value: 4.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 838 TEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTE 917
Cdd:COG3401 22 AVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 918 FTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLThFAVAGETI 997
Cdd:COG3401 102 SVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSP-DTSATAAV 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 998 LVDGVSEEFRL-----VDLLPSTHYTATMYATNG---PLTSGTIS-TNFSTLLDPPANLTASEVTRQSALISWQP-PRAE 1067
Cdd:COG3401 181 ATTSLTVTSTTlvdggGDIEPGTTYYYRVAATDTggeSAPSNEVSvTTPTTPPSAPTGLTATADTPGSVTLSWDPvTESD 260
|
250 260 270
....*....|....*....|....*....|....*....
gi 157384973 1068 IENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYT 1106
Cdd:COG3401 261 ATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYY 299
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
505-583 |
9.80e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.91 E-value: 9.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 505 DGPTQILVRDVSDTVAFVEWIPP-RAKVDFILLKYGLVGGEGGRTTFRL--QPPLSQYSVQALRPGSRYEVSVSAVRGTN 581
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpDDGITGYIVGYRVEYREEGSEWKEVnvTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 157384973 582 ES 583
Cdd:smart00060 82 EG 83
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
300-323 |
6.02e-05 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 41.18 E-value: 6.02e-05
10 20
....*....|....*....|....*.
gi 157384973 300 ACSGRGQCE--EGLCVCEEGYQGPDC 323
Cdd:pfam07974 1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
784-1111 |
2.50e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 45.38 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 784 HVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLV---------AVHGTVTSE 854
Cdd:COG3401 45 SVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGAtntgltssdEVPSPAVGT 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 855 PIVGSITTGIDPPKDITISNVTK---DSVMVSWSPPVASFDYYRVSYRPTQVG---RLDSSVVPNTVTEFTITRLNPATE 928
Cdd:COG3401 125 ATTATAVAGGAATAGTYALGAGLygvDGANASGTTASSVAGAGVVVSPDTSATaavATTSLTVTSTTLVDGGGDIEPGTT 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 929 YEISL---NSVRGREESERIC-TLVHTAMDNPVDLIATNITPTEALLQW-KAPVGEVENYVIVLTHFAVAGETILVDGVS 1003
Cdd:COG3401 205 YYYRVaatDTGGESAPSNEVSvTTPTTPPSAPTGLTATADTPGSVTLSWdPVTESDATGYRVYRSNSGDGPFTKVATVTT 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 1004 EEFRLVDLLPSTHYTATMYATNgplTSGTIS--------TNFSTLLDPPANLTASEVTRQSALISWQPPRAE-IENYVLT 1074
Cdd:COG3401 285 TSYTDTGLTNGTTYYYRVTAVD---AAGNESapsnvvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDAdVTGYNVY 361
|
330 340 350
....*....|....*....|....*....|....*...
gi 157384973 1075 YKSTDGSRKELIVD-AEDTWIRLEGLLENTDYTVLLQA 1111
Cdd:COG3401 362 RSTSGGGTYTKIAEtVTTTSYTDTGLTPGTTYYYKVTA 399
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
266-292 |
2.51e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.59 E-value: 2.51e-04
10 20
....*....|....*....|....*..
gi 157384973 266 CPGDCSGKGRCANGTCLCEEGYVGEDC 292
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
208-230 |
5.69e-04 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 38.48 E-value: 5.69e-04
|
| COG4733 |
COG4733 |
Phage-related protein, tail protein J [Mobilome: prophages, transposons]; |
494-692 |
1.07e-03 |
|
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
Pssm-ID: 443767 [Multi-domain] Cd Length: 978 Bit Score: 43.40 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 494 PPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDF-ILLKYGlvggeGGRTTFRLQPPLSQYSVQALRPGsRYEV 572
Cdd:COG4733 528 PPQWPPVNVTTSESLSVVAQGTAVTTLTVSWDAPAGAVAYeVEWRRD-----DGNWVSVPRTSGTSFEVPGIYAG-DYEV 601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 573 SVSAV----RGTNESDSATTQFTTEIDAPknLRVGSRTATSLD----LEWDNS-EAEVQEYKVVYSTLAGEQyhEVLVPR 643
Cdd:COG4733 602 RVRAInalgVSSAWAASSETTVTGKTAPP--PAPTGLTATGGLggitLSWSFPvDADTLRTEIRYSTTGDWA--SATVAQ 677
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 157384973 644 GIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDL 692
Cdd:COG4733 678 ALYPGNTYTLAGLKAGQTYYYRARAVDRSGNVSAWWVSGQASADAAGIL 726
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
297-324 |
1.26e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.26e-03
10 20
....*....|....*....|....*...
gi 157384973 297 CLNACSGRGQCEEGLCVCEEGYQGPDCS 324
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
321-539 |
1.26e-03 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 43.07 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 321 PDCSAVAPPEDLRVAGISDRSIELEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSgVTITELEPGLTYNISVYAV 398
Cdd:COG3401 322 TDLTPPAAPSGLTATAVGSSSITLSWTASSDadVTGYNVYRSTSGGGTYTKIAETVTTTS-YTDTGLTPGTTYYYKVTAV 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 399 ISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNN------------EGGVIAQVPSDV 466
Cdd:COG3401 401 DAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAvladggdtgnavPFTTTSSTVTAT 480
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157384973 467 TSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYG 539
Cdd:COG3401 481 TTDTTTANLSVTTGSLVGGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGDVLITDLVSL 553
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
269-292 |
6.89e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 35.40 E-value: 6.89e-03
10 20
....*....|....*....|....*.
gi 157384973 269 DCSGKGRC--ANGTCLCEEGYVGEDC 292
Cdd:pfam07974 1 ICSGRGTCvnQCGKCVCDSGYQGATC 26
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
689-921 |
8.38e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 40.14 E-value: 8.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 689 PRDLMVTASSETSISLIWTKASG--PIDHYRITftpSSGiaSEVTVPKDRTSYTLTDLEPGAEYIISVTAergrqQSLES 766
Cdd:COG3979 6 PTGLTASNVTSSSVSLSWDASTDnvGVTGYDVY---RGG--DQVATVTGLTAWTVTGLTPGTEYTFTVGA-----CDAAG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157384973 767 TVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVA 846
Cdd:COG3979 76 NVSAASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTTTII 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157384973 847 VHGTVTSEP--IVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTqVGRLDSSVVPNTVTEFTIT 921
Cdd:COG3979 156 TTGVEGGGGskTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNT-YWALNTLGVSDTPSGTTAT 231
|
|
| |
