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Conserved domains on  [gi|194385488|dbj|BAG65121|]
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unnamed protein product [Homo sapiens]

Protein Classification

IG_FLMN domain-containing protein( domain architecture ID 12215570)

IG_FLMN domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 180-269 4.27e-33

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 122.71  E-value: 4.27e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   180 ASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 257
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 194385488   258 VPGSPFSVKVTG 269
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 371-461 2.18e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 117.70  E-value: 2.18e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   371 AHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEH 448
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 194385488   449 IPDSPFVVPVASP 461
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 562-652 9.98e-27

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 104.22  E-value: 9.98e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   562 PGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGpY 638
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79

                           90
                   ....*....|....
gi 194385488   639 HIGGSPFKAKVTGP 652
Cdd:smart00557  80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 690-779 2.77e-26

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 103.07  E-value: 2.77e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   690 ASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEH 769
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 194385488   770 IPGSPYRVVV 779
Cdd:smart00557  81 IPGSPFTVKV 90
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 59-175 2.02e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.98  E-value: 2.02e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488    59 VTAYGPGLTHGVVNKPATFTVNTKDAGEGDdsmrmshlkvgsaadipinisetdlslLTATVVPPSGREEPCLLKRLRNG 138
Cdd:smart00557   4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGE---------------------------LEVEVTGPSGKKVPVEVKDNGDG 56

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 194385488   139 HVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQS 175
Cdd:smart00557  57 TYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 465-556 5.91e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.04  E-value: 5.91e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   465 ARRLTVSSLRESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTH 543
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 194385488   544 IPGSPFKIRVGEP 556
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-52 3.92e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 68.40  E-value: 3.92e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 194385488     2 PSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVD 52
Cdd:smart00557  41 PSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 180-269 4.27e-33

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 122.71  E-value: 4.27e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   180 ASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 257
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 194385488   258 VPGSPFSVKVTG 269
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 371-461 2.18e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 117.70  E-value: 2.18e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   371 AHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEH 448
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 194385488   449 IPDSPFVVPVASP 461
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 562-652 9.98e-27

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 104.22  E-value: 9.98e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   562 PGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGpY 638
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79

                           90
                   ....*....|....
gi 194385488   639 HIGGSPFKAKVTGP 652
Cdd:smart00557  80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 690-779 2.77e-26

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 103.07  E-value: 2.77e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   690 ASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEH 769
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 194385488   770 IPGSPYRVVV 779
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
178-263 2.54e-25

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 100.06  E-value: 2.54e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  178 GDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGyGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFAD 255
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 194385488  256 QHVPGSPF 263
Cdd:pfam00630  81 QHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
369-455 5.03e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.59  E-value: 5.03e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  369 GGAHKVRAGGPGLERAEAGVPAEFSIWTREAGaGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNE 446
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 194385488  447 EHIPDSPFV 455
Cdd:pfam00630  81 QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 59-175 2.02e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.98  E-value: 2.02e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488    59 VTAYGPGLTHGVVNKPATFTVNTKDAGEGDdsmrmshlkvgsaadipinisetdlslLTATVVPPSGREEPCLLKRLRNG 138
Cdd:smart00557   4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGE---------------------------LEVEVTGPSGKKVPVEVKDNGDG 56

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 194385488   139 HVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQS 175
Cdd:smart00557  57 TYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 465-556 5.91e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.04  E-value: 5.91e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   465 ARRLTVSSLRESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTH 543
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 194385488   544 IPGSPFKIRVGEP 556
Cdd:smart00557  81 IPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
560-646 5.33e-20

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 85.03  E-value: 5.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  560 GDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGaGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGG 636
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFNG 80

                          90
                  ....*....|
gi 194385488  637 pYHIGGSPFK 646
Cdd:pfam00630  81 -QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
687-776 1.80e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 83.49  E-value: 1.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  687 PADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNmLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWG 766
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 194385488  767 DEHIPGSPYR 776
Cdd:pfam00630  80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
462-550 4.37e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 82.34  E-value: 4.37e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  462 SGDARRLTVSSLRESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG 541
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 194385488  542 THIPGSPFK 550
Cdd:pfam00630  81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
59-167 8.07e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 70.40  E-value: 8.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   59 VTAYGPGLTHGVVNKPATFTVNTKDAGEGddsmrmshlkvgsaadipinisetdlslLTATVVPPSGREEPCLLKRLRNG 138
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAGGE----------------------------GEVEVTGPDGSPVPVEVTDNGDG 58

                          90       100
                  ....*....|....*....|....*....
gi 194385488  139 HVGISFVPKETGEHLVHVKKNGQHVASSP 167
Cdd:pfam00630  59 TYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-52 3.92e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 68.40  E-value: 3.92e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 194385488     2 PSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVD 52
Cdd:smart00557  41 PSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
2-46 4.33e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.61  E-value: 4.33e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 194385488    2 PSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSP 46
Cdd:pfam00630  43 PDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 180-269 4.27e-33

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 122.71  E-value: 4.27e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   180 ASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 257
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 194385488   258 VPGSPFSVKVTG 269
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 371-461 2.18e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 117.70  E-value: 2.18e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   371 AHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEH 448
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 194385488   449 IPDSPFVVPVASP 461
Cdd:smart00557  81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 562-652 9.98e-27

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 104.22  E-value: 9.98e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   562 PGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGpY 638
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79

                           90
                   ....*....|....
gi 194385488   639 HIGGSPFKAKVTGP 652
Cdd:smart00557  80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 690-779 2.77e-26

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 103.07  E-value: 2.77e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   690 ASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEH 769
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 194385488   770 IPGSPYRVVV 779
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
178-263 2.54e-25

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 100.06  E-value: 2.54e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  178 GDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGyGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFAD 255
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 194385488  256 QHVPGSPF 263
Cdd:pfam00630  81 QHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
369-455 5.03e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.59  E-value: 5.03e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  369 GGAHKVRAGGPGLERAEAGVPAEFSIWTREAGaGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNE 446
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 194385488  447 EHIPDSPFV 455
Cdd:pfam00630  81 QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 59-175 2.02e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.98  E-value: 2.02e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488    59 VTAYGPGLTHGVVNKPATFTVNTKDAGEGDdsmrmshlkvgsaadipinisetdlslLTATVVPPSGREEPCLLKRLRNG 138
Cdd:smart00557   4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGE---------------------------LEVEVTGPSGKKVPVEVKDNGDG 56

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 194385488   139 HVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQS 175
Cdd:smart00557  57 TYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 465-556 5.91e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.04  E-value: 5.91e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   465 ARRLTVSSLRESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTH 543
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|...
gi 194385488   544 IPGSPFKIRVGEP 556
Cdd:smart00557  81 IPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
560-646 5.33e-20

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 85.03  E-value: 5.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  560 GDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGaGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGG 636
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFNG 80

                          90
                  ....*....|
gi 194385488  637 pYHIGGSPFK 646
Cdd:pfam00630  81 -QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
687-776 1.80e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 83.49  E-value: 1.80e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  687 PADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNmLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWG 766
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 194385488  767 DEHIPGSPYR 776
Cdd:pfam00630  80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
462-550 4.37e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 82.34  E-value: 4.37e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488  462 SGDARRLTVSSLRESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG 541
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 194385488  542 THIPGSPFK 550
Cdd:pfam00630  81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
59-167 8.07e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 70.40  E-value: 8.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194385488   59 VTAYGPGLTHGVVNKPATFTVNTKDAGEGddsmrmshlkvgsaadipinisetdlslLTATVVPPSGREEPCLLKRLRNG 138
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAGGE----------------------------GEVEVTGPDGSPVPVEVTDNGDG 58

                          90       100
                  ....*....|....*....|....*....
gi 194385488  139 HVGISFVPKETGEHLVHVKKNGQHVASSP 167
Cdd:pfam00630  59 TYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-52 3.92e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 68.40  E-value: 3.92e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 194385488     2 PSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVD 52
Cdd:smart00557  41 PSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
2-46 4.33e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.61  E-value: 4.33e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 194385488    2 PSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSP 46
Cdd:pfam00630  43 PDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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