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Conserved domains on  [gi|9886738|dbj|BAB11983|]
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junctophilin type3 [Homo sapiens]

Protein Classification

MORN repeat-containing protein( domain architecture ID 11468649)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-144 1.15e-28

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 115.82  E-value: 1.15e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    3 SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGqGEYTGSWSHG-FEVLGVYTWPSGNTYQGTWAQGKRHGIG-LESKGK 80
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGtLTYANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9886738   81 WVYKGEWTHGFKGRYGVRECAgNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYTYA-DGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 super family cl33654
phosphatidylinositol phosphate kinase; Provisional
 287-345 2.47e-05

phosphatidylinositol phosphate kinase; Provisional


The actual alignment was detected with superfamily member PLN03185:

Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.91  E-value: 2.47e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 9886738   287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Cdd:PLN03185  56 TYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEG 114
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-144 1.15e-28

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 115.82  E-value: 1.15e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    3 SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGqGEYTGSWSHG-FEVLGVYTWPSGNTYQGTWAQGKRHGIG-LESKGK 80
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGtLTYANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9886738   81 WVYKGEWTHGFKGRYGVRECAgNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYTYA-DGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 5-144 1.73e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.91  E-value: 1.73e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738     5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFevlGVYTWPSGNTYQGTWAQGKRHGIGL------ 75
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYqrypng 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    76 ------------ESKGKW------VYKGEWTHGFKGRYGVRECAgNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGG 137
Cdd:PLN03185 101 dvfegswiqglqEGPGKYtwangnVYLGDMKGGKMSGKGTLTWV-SGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRG 179


                 ....*..
gi 9886738   138 MRQGYGV 144
Cdd:PLN03185 180 LKDGKGV 186
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 287-345 2.47e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.91  E-value: 2.47e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 9886738   287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Cdd:PLN03185  56 TYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEG 114
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 311-333 1.10e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 1.10e-04
                          10        20
                  ....*....|....*....|...
gi 9886738    311 YEGEWASNRRHGYGCMTFPDGTK 333
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 107-129 2.21e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.93  E-value: 2.21e-04
                          10        20
                  ....*....|....*....|...
gi 9886738    107 YEGTWSNGLQDGYGTETYSDGGT 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
310-330 9.07e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 36.93  E-value: 9.07e-04
                           10        20
                   ....*....|....*....|.
gi 9886738     310 KYEGEWASNRRHGYGCMTFPD 330
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
105-126 9.27e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 34.24  E-value: 9.27e-03
                           10        20
                   ....*....|....*....|..
gi 9886738     105 AKYEGTWSNGLQDGYGTETYSD 126
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-144 1.15e-28

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 115.82  E-value: 1.15e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    3 SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGqGEYTGSWSHG-FEVLGVYTWPSGNTYQGTWAQGKRHGIG-LESKGK 80
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGtLTYANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9886738   81 WVYKGEWTHGFKGRYGVRECAgNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYTYA-DGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
1-135 2.67e-27

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 111.97  E-value: 2.67e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    1 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGqGEYTGSWSHG-FEVLGVYTWPSGNTYQGTWAQGKRHGIG-LESK 78
Cdd:COG4642 136 RGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADG-DRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHGQGtYTYA 214

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 9886738   79 GKWVYKGEWTHGFKGRYGVRECAgNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWV 135
Cdd:COG4642 215 DGDRYEGEFKNGKRHGQGTLTYA-DGDRYEGEFKNGKRHGQGTMTYADGSVYEGEWK 270
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
4-340 1.10e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 1.10e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGiglesKGKWVY 83
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHG-----QGTLTY 167

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738   84 KgewthgfkgrygvrecagNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGvrqsvpygmaaVIRSPlrts 163
Cdd:COG4642 168 A------------------DGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQG-----------TYTYA---- 214

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738  164 inslrsehtNGtplhpdaspavdgspavsrggfvlvahsdseilkskkkglfrrsllsglklrksesksslasqrskqss 243
Cdd:COG4642 215 ---------DG--------------------------------------------------------------------- 216

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738  244 frseagmstvsstasdihstislgeaeaelavieddidatttETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGY 323
Cdd:COG4642 217 ------------------------------------------DRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQ 254

                       330
                ....*....|....*..
gi 9886738  324 GCMTFPDGTKEEGKYKQ 340
Cdd:COG4642 255 GTMTYADGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 5-144 1.73e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.91  E-value: 1.73e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738     5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFevlGVYTWPSGNTYQGTWAQGKRHGIGL------ 75
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYqrypng 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    76 ------------ESKGKW------VYKGEWTHGFKGRYGVRECAgNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGG 137
Cdd:PLN03185 101 dvfegswiqglqEGPGKYtwangnVYLGDMKGGKMSGKGTLTWV-SGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRG 179


                 ....*..
gi 9886738   138 MRQGYGV 144
Cdd:PLN03185 180 LKDGKGV 186
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
4-345 3.01e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 91.17  E-value: 3.01e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    4 GGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVY 83
Cdd:COG4642  35 GGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGG 114

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738   84 KGEWTHGFKGRYGVRECAG------------NGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQsvpyg 151
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADggrggggiytfpNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT----- 189

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738  152 maavirsplrtsinslrseHTNGTplhpdaspavdgspavsrggfvlvahsdseilkskkkglfrrsllsglklrksesk 231
Cdd:COG4642 190 -------------------YANGD-------------------------------------------------------- 194

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738  232 sslasqrskqssfrseagmstvsstasdihstislgeaeaelavieddidattteTYVGEWKNDKRSGFGVSQRSDGLKY 311
Cdd:COG4642 195 -------------------------------------------------------VYEGEFKNGQRHGQGTYTYADGDRY 219

                       330       340       350
                ....*....|....*....|....*....|....
gi 9886738  312 EGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Cdd:COG4642 220 EGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHG 253
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 39-151 1.40e-10

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 64.85  E-value: 1.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738    39 YTGSWSHGF-EVLGVYTWPSGNTYQGTWAQGKRHGIGleskgkwvyKGEWThgfkgrygvrecagNGAKYEGTWSNGLQD 117
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---------KISWP--------------SGATYEGEFSGGYMH 67

                         90       100       110
                 ....*....|....*....|....*....|....
gi 9886738   118 GYGTETYSDGGTYQGQWVGGMRQGYGvRQSVPYG 151
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG-YQRYPNG 100
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 287-345 2.47e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.91  E-value: 2.47e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 9886738   287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Cdd:PLN03185  56 TYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEG 114
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 287-350 4.42e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.14  E-value: 4.42e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9886738   287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKN 350
Cdd:PLN03185  33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQR 96
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 286-338 7.45e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 46.36  E-value: 7.45e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 9886738   286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKY 338
Cdd:PLN03185   9 DFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEF 61
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 311-333 1.10e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 1.10e-04
                          10        20
                  ....*....|....*....|...
gi 9886738    311 YEGEWASNRRHGYGCMTFPDGTK 333
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 103-143 1.89e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 44.82  E-value: 1.89e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 9886738   103 NGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYG 143
Cdd:PLN03185   7 NGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG 47
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 107-129 2.21e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.93  E-value: 2.21e-04
                          10        20
                  ....*....|....*....|...
gi 9886738    107 YEGTWSNGLQDGYGTETYSDGGT 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
310-330 9.07e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 36.93  E-value: 9.07e-04
                           10        20
                   ....*....|....*....|.
gi 9886738     310 KYEGEWASNRRHGYGCMTFPD 330
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
37-127 3.22e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 38.90  E-value: 3.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9886738   37 GEYTGSWSHGFEVLGVYTW--PSGN-TYQGTWAQGKRHGIGLE--SKGKWVYKGEWTHGFK-GRYgvRECAGNGA-KYEG 109
Cdd:COG2849  54 KLGKGLGKYKKGKLGEWKTyyPNGQlKSEGTYKNGKLEGEWKEyyENGKLKSEGNYKNGKLhGEW--KEYYENGKlKEEG 131

                        90
                ....*....|....*...
gi 9886738  110 TWSNGLQDGYGTETYSDG 127
Cdd:COG2849 132 NYKNGKKDGVWKYYDENG 149
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 15-35 6.03e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 34.69  E-value: 6.03e-03
                          10        20
                  ....*....|....*....|.
gi 9886738     15 YCGGWEDGKAHGHGVCTGPKG 35
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
105-126 9.27e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 34.24  E-value: 9.27e-03
                           10        20
                   ....*....|....*....|..
gi 9886738     105 AKYEGTWSNGLQDGYGTETYSD 126
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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