2XAF,4CZZ,6Z2J


Conserved Protein Domain Family
ELM2

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pfam01448: ELM2 
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ELM2 domain
The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex. The domain is usually found to the N terminus of a myb-like DNA binding domain pfam00249. ELM2 is also found associated with an ARID DNA binding domain pfam01388 in Swiss:O82364. This suggests that ELM2 may also be involved in DNA binding, or perhaps is a protein-protein interaction domain.
Statistics
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PSSM-Id: 460214
Aligned: 177 rows
Threshold Bit Score: 30.6586
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2XAF_B               102 MRVGPQYQAVVPD-FDPAKlARRS--QERDNLGm---lVWS-----P--NQNLSEAK---LDEYIAIAKE 155 
XP_015196168         224 INVGVRFQAEIPP-LCSPL-LVLQ--EEHPAQL-----VWT-----PwgDISHNAVTqhrVTEFLELCCC 279 
XP_018669477        1310 INIGSRFQANLPN-RENPS-NKLK--LKHKADR-----VWD-----RvpNDEQVETH---LENLMELSCS 1362
EKC35058            1353 VNIGSQYQAEIPPyNENRS-EVMK--VVCKEDL-----VWA-----PssVGDNSEED---VQYYQEFSCS 1406
CDS38000            1219 INVGTAYQAEVPE-FVdvvgayhd------dtrvydilVWN-----PknIDENDPKTresLSNLMNLARS 1276
XP_001847871         872 INIGHDYQATIPD-CYGSS-PSYHnlSHHLDQQ-----LWD-----P-----TVAQNdqqIARFVELSRS 924 
WGS:AANI:GJ23569-PB 1660 VNLGSTYQAQIPA-CKSPE-ESTK--ETMSADL-----LWD-----P--SVQIDEKI---LMRYIDLSKS 1710
KPU79511            1651 VNLGSTYQAQIPS-CRPQE-EALR--E--DVGAe---mMWN-----PevQ--EDEKI---LMRYIDLSKS 1701
Q9LMG9               128 VPIGSDYQADIPE-CVKEE-ANDQ--S--GQGVgydeeqvtgkcviP-----MPDCE----TEVCKIGKG 182  thale cress
XP_675109             14 INIGEKHQAKIPD-LIVSE-ENVQ--ENKNNIIdttseVVDvpknlT-------------KRAKVEEVPK 66  
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