Conserved Protein Domain Family
FN3

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COG3401: FN3 
Fibronectin type 3 domain [General function prediction only]
Statistics
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PSSM-Id: 442628
Aligned: 144 rows
Threshold Bit Score: 81.9724
Created: 9-Feb-2022
Updated: 24-Feb-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_041587694  128 QSTMYGAPVESPYIWVTAFPATTNPNGQKGVTLDDGSTSGPYIDRNGTAHDEVFSVNVKVDDQMPFG------------- 194 
WP_012390114  351 RKEESDFFDLAYSDKPSFTDLAVSPNSTYGYRILAIGAEEVSVASMEVEGFTSSDSNNVGNVTQVVGl------------ 418 
WP_012476558  235 GSGEVLGAQSLVVLGFNDKKKAFKVWNTWGTQWGDQGYLWISYESFPKHTKSIYVADSAEENQLLSEsklmsh------- 307 
YP_002249691  195 KFNEKIPSPEGLIEQRPVIKEVLTNAKDSPFGKGKVIQVGAEGDRGMVATFDIGNFKKGVPMKETQPg------------ 262 
WP_015925822  577 LAMSRIDPKIDFTKDNTDTYYRWGDKAPDPKVNADHYSVVWSGYIMPEFDADYTFYTRTDDGVKLWIdinrngifdinel 656 
NP_714802     190 NEVKAQLSEGKPVVAGVLVYENFFNLKGDQIYKEGLGKTYGGHAIALVGYDDSKNAVKFINSWGTDWgdqgygyidyrwf 269 
WP_083847791  256 NGHAMVLIGYDDNKRSPKGHRGAFKIMDSDGNNWGTNGYGWVSYEFAQQFFYAAYALRDWQPQGDAPig----------- 324 
WP_014854768  460 RSATNLKVGPNPPSSNFVVWWDGDLERELLDNNNIRKYNGSNNPVLLLANGCSSNNGSKATPSLQADlfgdwreeviwrt 539 
WP_117177988  605 DGNRYTWRPDIWFRISRTGNTFTVYESNNKDVWFEVGSRTIDMAENVYVGLFNSSGNTTSLNTTRYD------------- 671 
WP_119050027  516 WVKIDRVGDVIATYYSPDGVSWATEVQGRYAGFTGTAYIGLAVCSNANGVPMTATFSNVSVTGGQGGm------------ 583 
WP_041587694      --------------------------------------------------------------------------------     
WP_012390114      --------------------------------------------------------------------------------     
WP_012476558      --------------------------------------------------------------------------------     
YP_002249691      --------------------------------------------------------------------------------     
WP_015925822  657 lisnwq-------------------------------------------------------------------------- 662 
NP_714802     270 tkicqgafvmidqvetvidqgkpdsntpeptsvandsnpiapssitasqgsfidkvlinwevvpgavgyeihrkgpgdsn 349 
WP_083847791      --------------------------------------------------------------------------------     
WP_014854768  540 sdnnslr------------------------------------------------------------------------- 546 
WP_117177988      --------------------------------------------------------------------------------     
WP_119050027      --------------------------------------------------------------------------------     
WP_041587694  195 ---------------------TY--NLRVLGIGt-----sSTGRLGYNe------QTVAVTVyd------dtTPpdwsPS 234 
WP_012390114      --------------------------------------------------------------------------------     
WP_012476558  308 ------------------------------------ldsleFGEHNLF-------------------------------- 319 
YP_002249691  263 ---------------------iYigEYVVMPGDnvkeapiIVSLRKPGgy---dtQWIDVSGfvt----idtTP------ 308 
WP_015925822  663 ---khsetennsrsvqmekgkKY--RIRMEYYE-------NEYDAVAKllwsnpsKAKEVVPnsqlfvdgtiNI----PK 726 
NP_714802     350 fgkiglsgtnsfnddgvqpnlAY--KYKILTLT-------DSSASDLSq-----gEVIGFAK----------TEel-kP- 403 
WP_083847791  325 --------------------eK--------------------------------------------------------LS 328 
WP_014854768  547 --iyttniktdyrlvtlmhdrQY--RLAIAWQN-------VGYNQPPH-------TSFFVGKsmli--pdrlKP----PS 602 
WP_117177988  672 ----------------------Hvait-----------------------------------------glvsNA----PE 684 
WP_119050027  584 -----------------------------------------------------------------------vIL----PE 588 
WP_041587694  235 KT--ANIRFSN-QTAGSVTITWDPASdpapnSTGVDGYEIYRATSAsGPY-EYIGY--S-TST--SY-TDRE-LLAETTY 303 
WP_012390114  419 ----SGIVFSS-GNTTSVQLTWSEID-------GATNYSIAKADSS-FQW-KTIGN--S-KSA--DY-VDVS-PKSGEVN 477 
WP_012476558  320 PP--KEVYASRgDFSDRIRISWSSEK-------RAIGYEVYRKRKIdTKY-QLVGL--S-KQP--YF-DDFG-VQKNTAY 382 
YP_002249691  309 PPqvTGLRAKG--FHDRIEISWQALKn----VPDLKGYRVLRSEQPlSGF-KEITT------TefNFvEDKT-VEYGKVY 374 
WP_015925822  727 tP--TNLKADL-KNDGSVVLSWDSV-------LEAQGYKIYQTDWQ-GNT-SII-N--V-KDN--SY-TVLN-LASG-EY 785 
NP_714802     404 PPkvLGVKATQgQYDNKVELVWEPGD-------ASSEYQIFKWNKTqKRY-SPIGTskI---N--SY-VDTSaAKKGIVE 469 
WP_083847791  329 PP--KNLRASQgTESDSITVTWAAST-------GALGYQVLRSDSAdGSF-GQISE--T-AET--HF-KDYS-IDSGRNY 391 
WP_014854768  603 KP--MNLRGVS--LGDTVLIEWDSNV-----EADLAGYILYKGKSPhD-FlDSLDVg---NVT--SY-LDTN-VTYDTTY 665 
WP_117177988  685 AP--ANVTASP--GNTQNILDWDEVT-------GASSYTLKRSTTSgEPY-EIVAAn-L-NVT--EY-TDTG-LENGTTY 746 
WP_119050027  589 AP--HSVYAYA--GNNQVQLRWLSSF-------GADTYTLKRANSEaGPY-STIAA--IlSGN--SF-MDNN-VMNGQAY 650 
WP_041587694  304 YYMVTAVDKCG---NVSPYSFSS-STTTlapprtdgAAPL-APQGLKASLten--pldPS-KRIVRLEWSANTEG-DII- 373 
WP_012390114  478 YYKVSAVLGSK---LSSDWSDSI-AVEVan----qnLLPN-QVSQLSATN--------GDyANKIQLNWKAA--P-GAK- 536 
WP_012476558  383 HYRVASLD-ENylsKPSIDSN---DGYAse-----pTKTA-GILPVTNLRas----vaPT-NDRIVLEWDNQSI---PT- 443 
YP_002249691  375 YYRVVAYDTAG---NESEIQDAK-KAFL----------TAkEPQIISGSI-----------EKDTVLSG----------- 418 
WP_015925822  786 KFSVSAWNEAG---E-SAKSESV-KVVVgl----------gAPQNLKGTV---------N-KKTINLSWDSVDT---AS- 836 
NP_714802     470 IYVVSAKL-GG---KTGEPSDAA-SGFTsq----pkTPPA-KPLGLIASR--------GAyQNKVELKWQKVSG---AS- 527 
WP_083847791  392 YYRIVALNETE---KTSADESLVaSGYAae-----qKIl-gAVQGLKGEL--------LP-NGQIRLSWQGVEL---AT- 449 
WP_014854768  666 YYALRAYDTDG---NKSDLSDII-TVTPt-------LRPD-APAGVSYRY---------D-NNSCLLLWKYDDID-LIS- 721 
WP_117177988  747 YYVVSAANLSG---E-SVNSLEI-SVAPe------lAIAP-VPEDVTAQS--------VS-GQQINLFWNSSLS---AT- 801 
WP_119050027  651 YYKVCAVNTAG---T-SADAPAD-SATPy------------APYVLQTLDglyriivtHS-GKAIEVKNGSTADsalVTq 712 
WP_041587694  374 -GYHVYR---STEPAg----NYARLTQTpcnstvsyqissspnvVmK-A-VYFT--DS--TVK-YGTT------YYYKVV 432 
WP_012390114  537 -QYFLFRfdeNAEPSg----QFEV----------------------A-G-TSYTdsDT--TIQ-NGKS------YIYTVI 578 
WP_012476558  444 -TYIVYK---WNAMAr----IFRFLGKt------------------E-K-NTYT--DLk-ASR-NGDN------EIYQVV 485 
YP_002249691  419 -NYIVKN---Slwi-------pkgLTLT----------------I-EpE-TRLMf-DEnaQLKvEGKIvinakdFPVEFV 468 
WP_015925822  837 -GYRLYR---V--LDg----IQTTVLSV------------------D---SKYT--DS--KVS-YGKV------YKYFVS 874 
NP_714802     528 -KYLIFRy---IKSGwigggAWEKISET------------------G-K-EEFI--DE--NL--PARY------AYYSVT 571 
WP_083847791  450 -SYKVTK---ENFASg----AFTTIATP------------------R-G-TTHT--DI--RPA-AGPN-------TYAVI 489 
WP_014854768  722 -HVNIYR---SESID---------MSDPvk------------fkLdK-NfTSYV--DK--NLI-KGKT------YYYTLT 764 
WP_117177988  802 -SYNVKR---ATASGg----PYTIIA-S----------------P-D-T-TAFS--DT--DVN-HSTT------YYYVVS 842 
WP_119050027  713 nTYSFKSnq-------------hwII-Sp---------------L-S-G-TDYK--IT--NLL-SGKV------MDIVGN 749 
WP_041587694  433 AVDVAGkMSAMSSYVSATptvdygvsp----------------------------------------------------- 459 
WP_012390114  579 SANDMGy----AEP------------------------------------------------------------------ 588 
WP_012476558  486 PERNQL-EGEASFYVSAHldpsevlkprpqhftaskglypgvtvlqwegspsalayhifrktsgt----------wkria 554 
YP_002249691  469 PV------------------------------------------------------------------------------ 470 
WP_015925822  875 AI-KDG-------------------------------------------------------------------------- 879 
NP_714802     572 AVNTEGkNGPFSSFayg--------------------------------------------------------------- 588 
WP_083847791  490 AIg----------------------------------------------------------------------------- 492 
WP_014854768  765 VTDTNNaESFHTDIIQITpadsfvfqsedanligsvfvennhlgyhgaaftnfdasnsaveftnmpgfgggprallfrya 844 
WP_117177988  843 AINELG-ESEDSEEV----------------------------------------------------------------- 856 
WP_119050027  750 AITDGArIEQR--------------------------------------------------------------------- 760 
WP_041587694  460 ---------------------------------hgnyksssNDTLCQNCHSTHSSRGAELIYYSSITDSCYTCHDGSQSK 506 
WP_012390114  589 -----------------------------------------SEVAFGKTDPGLTKRAGGVTLAAPKQVVSNPVGKDKQVS 627 
WP_012476558  555 kttelqfkeedpsgkesfyavtsefegemfslpsepdvgyaSLIAGRSLSLKAPNLTVTENRKSGEFWFSWNAIPKVTSY 634 
YP_002249691  471 -----------------------------------------GNKKWKGIVLEGGYIEMNGFRIKNAETGISLNSSGGVIE 509 
WP_015925822  880 -----------------------------------------YEGAKSREITIAVPPDAPANLKAAREGESVQLRWNPAQG 918 
NP_714802     589 ---------------------------------------ytDPNKQRGVKLSSPENVKGVLDVKEAKISITWDPVKEASE 629 
WP_083847791  493 ----------------------------------------rSDEAPPSASITVEGKSGMPGRVEGLQASAGVFADKIQLT 532 
WP_014854768  845 lgntdrtgslivngqatnltmkgtgdwtnyvtdsvevnlnsGYDNTIRFSATGSDFGNLDEIIIKSTPLTSVETVSELPA 924 
WP_117177988  857 -----------------------------------------IATPGRSGYWKFDETEGSTATDSWGNGNAALSSGATFVE 895 
WP_119050027  761 -----------------------------------------TWSATDSGQIWFIKDRGNGTFSIVAKQSQKALEVPGSNT 799 
WP_041587694  507 YNTKAAFDPVNNPSHHKVPEGRYSCDVCHNPHYSSPMVIQKDGDTVTETVYRLLSTVSKEDGRIKRRGNDFCWACHGLNS 586 
WP_012390114  628 LKWDAVKDSFEYYIYRKPIQNGKPGKIEFVSSVEGKKTNFTESFPGKSGDLFLYSVRSKSEFGSESKDSNFVSVFWNEPK 707 
WP_012476558  635 KILMRKKNEEEWSLVKETSDTNFKLQNLAKNQFYFFVIQSVQKGIGESLYSVPVTAVLSETIQDVKKVKTFGESAIQKFI 714 
YP_002249691  510 NGIISDNDKGISVLGIPSPSIKNLTISGNKTGIELVKTNSIIYLNSLFQNETGIKIIGFSGEIRDNNIYDNNLNIYSETF 589 
WP_015925822  919 AQSYSVLRCNSSDGTYEIIKEGITGTSFKDDSVPETTNSSGVKYYYKVTAVANGVAGPCSNIASVIMYPFVETQLGFVTY 998 
NP_714802     630 YYVFRKKRGESKWTFLGSAGNKNTYVAEVPEKETLFLYSVTSKTDLGGESGNSLPVSAVISTAVVAPKKRTFGGDSSLEK 709 
WP_083847791  533 WTAVPGADRYWVVRFNASSGLWQEAGYVKTNAFSDSSPEAKSGTVQAYSVRAISGIQAGPAALPARGHANTNVNRTGKPP 612 
WP_014854768  925 EFLLYQNYPNPFNPSTVITYTIPATVKSGASGIHVMLRVYDALGRRVATLVNEQKEPGNYRIEFNADNLPSGIYFYQLLA 1004
WP_117177988  896 GLMGNAVSLNGNDGYVTLSEGVVSSLTDFSISTWVKLDKVDNWARIFDFGTGTSNYMFITPKNGSNGNLRYAIKTGDVEQ 975 
WP_119050027  800 ADGVTMDIYRWTDGPNQIFQIEPVTASAIDSAYQRKLAEAIQLRDTTVVSTTNELGKFPVAARAQLNDSISHVQSLYNPQ 879 
WP_041587694  587 DLPNPFGQDHKTAFINSKHNTLEPSSTLTGITCRNCHAPHGSKDYPLIITSNSANFCITCHKDHGFTS 654 
WP_012390114  708 PFVKKRAMSLEELPSTFSGKWTSMYWNPKLGPQNLQMEIQGNGQDFVAKLKLNDKEIKQFSGSWTPGS 775 
WP_012476558  715 GPWTAMYWDGKNKVKPVRLTIEAEDVEGNIIMKWNENQIFRGKNIVDSDLIEEKGKWKIKLSPNYESL 782 
YP_002249691  590 LKIAPNYFGSINSDEMRLRNIQISSVYDAKLPEGKLVNPITNPYAKLSQEERQRKATEFVIEAGEYFR 657 
WP_015925822  999 NIINNSKNPNLEFVLGSYVPVSFELQLKNTTSNPGIVMDTEMVNKMNINEKPFFLELVSKNIKVTIKK 1066
NP_714802     710 FKGPWTAMAWDGNNGVSQVLLEIESQDNVNYTVKFNKKKIFEGKYVEESPIIDKDGKFKIEIEKTGDA 777 
WP_083847791  613 LAPANLKATATKTGVLLQFAKVADAADYLVFRKAPGESNWNFIAATKTPRFSHELDVSGKLFFYAVRA 680 
WP_014854768 1005 GNFISTKKMILLR------------------------------------------------------- 1017
WP_117177988  976 QINTSVALTTERWYHLAVTQSGTTAILYLDGAEVGRNTSMTLSPSSLGNTTQNWIGKSQWPDPLLDGL 1043
WP_119050027  880 STVIEISGYVTILENAIKRYKASMYYGMNTLPNGNYYLKTLTGDSLWTKNNTNTPLFDTVNSDPLLQV 947 
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