2JGZ,4Y72,2B9R


Conserved Protein Domain Family
CYCLIN_CCNB1_rpt2
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cd20569: CYCLIN_CCNB1_rpt2 
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second cyclin box found in G2/mitotic-specific cyclin-B1 (CCNB1) and similar proteins
CCNB1 is essential for the control of the cell cycle at the G2/M (mitosis) transition. It is required for embryo development. Over-expression of human CCNB1 has been found in numerous cancers and has been associated with tumor aggressiveness. CCNB1 contains two cyclin boxes. This model corresponds to the second one. The cyclin box is a protein binding domain.
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Statistics
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PSSM-Id: 410272
Aligned: 9 rows
Threshold Bit Score: 238.251
Created: 12-Apr-2019
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2JGZ_B       134 PLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMvHFPPSQIAAGAFCLALKILDnGEWTPTLQHYLSYTEESLLPV 213 human
4Y72_B       140 PLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMvHFPPSQIAAGAFSLALKILDnGEWTPTLQHYLSYTEESLLPV 219 human
2B9R_A       136 PLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMvHFPPSQIAAGAFSLALKILDnGEWTPTLQHYLSYTEESLLPV 215 human
Q92162       266 PLPLQFLRRASKIGDVTAEHHTLAKYFLELTMVDYDMvHFPPSQVASARYALTLKVFNcGDWTPTLQHYMGYTEDSLVPV 345 goldfish
116176       300 PLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMvHFPPSQIAAGAFCLALKILDnGEWTPTLQHYLSYTEESLLPV 379 human
P13350       266 PLPLHFLRRASKIGEVTAEQHSLAKYLMELVMVDYDMvHFTPSQIAAASSCLSLKILNaGDWTPTLHHYMAYSEEDLVPV 345 African clawed ...
KYO48526     270 PLPLHFLRRASKIGEVDLEQHTLAKYLMELCIVDYEMvHYPPSQIAAAAFCLALKILDgGEWTPTLQHYMAYAESDLLPV 349 American alligator
XP_006010328 272 PLPLHFLRRASKTAEATSEQHTLAKFLMELSMVDYEMaHFPPSQIAAAAFCLALKVLDaGAWTPVLQHHMSYTEEDLIPV 351 coelacanth
NP_001279224 262 PLPLHFLRRSSKIAEVSSEQHTLAKYLMELTIVDYEMvHYPPSKIAAAAFCLAQKVLNsGDWNDVLQHYMAYKEDELVSV 341 elephant shark

2JGZ_B       214 MQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS 254 human
4Y72_B       220 MQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS 260 human
2B9R_A       216 MQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS 256 human
Q92162       346 MQHIARNVVRVNEGLSKHLAVKNKYSSQKQMRIASISQLKS 386 goldfish
116176       380 MQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS 420 human
P13350       346 MQHMAKNIIKVNKGLTKHLTVKNKYASSKQMKISTIPQLRS 386 African clawed frog
KYO48526     350 MQHMAKNVIQVNQGLTKRMTIKNKYASSKNVKISTLSQLNS 390 American alligator
XP_006010328 352 MEHMAKNVVKVNEGLTKHMAVKNKYTSSKQMKISTLPQLKS 392 coelacanth
NP_001279224 342 MQHMAKNIVKVNQGLTKHVTVKNEYTSSKQMKISTISQLRS 382 elephant shark
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