Conserved Protein Domain Family
KCT2
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pfam17818: KCT2 (this model, PSSM-Id:375354 is obsolete and has been replaced by 407686)
Keratinocyte-associated gene product
This entry includes Keratinocyte-associated transmembrane protein 2 found in humans. Functional studies show that KCP2 localizes to the endoplasmic reticulum, consistent with a role in protein biosynthesis, and has a functional KKxx retrieval signal at its cytosolic C-terminus.
Links
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Statistics
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PSSM-Id: 375354
Aligned: 6 rows
Threshold Bit Score: 239.427
Created: 22-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
KFV12611      45 PTTAKINlvTAVKPPTA-EGDSPPYVPSRVVTASPVSQMNVDASEDTKIEEED-LLtdlkdTLNSSPSVIKETVESdgGD 122 red-crested turaco
XP_003123986  79 PSLSQVS--TTLAPATRtEKSRVASVSPYSSPATSLSQEEADNNEDPSIEEED-LL-----TLNSSPPTARDTLDN--GD 148 pig
XP_005001320  76 PSKAHVT--TTLPPPTAtEKSRAPTAAPRPPPTSSPLPEEAEDHEDPSLEEDEgLL-----TPNSPPSPVKDPLDN--GD 146 domestic guinea...
KFO26599      59 PSVSRVT--TTLPAPTGpEKSRGTLAAPHPSLTTSVLPEAADNNADQSLEEED-LL-----VPNGSPSPARDALDN--GD 128 Damara mole-rat
KFW79987      40 PTTAKISsvTAGKAPTA-KGDS----SSSVLPASLVPP--VDASEDTKIEDED-LLtdlkdTLNSSPPIIKETLESd-GD 110 golden-collared...
NP_694757     72 PSVSQIS--TTLSPASA-EKSGSSSAAPTPTAAPSAPEEEADSNEDPSMEEED-LL-----ALNSSPATGKDTLDN--GD 140 house mouse

KFV12611     123 dYGT--YEMTSNSRynpdlempEdDDSDT----ISNYNEEIKSLDEKIKDVSVTGLEEEEEDSHFFFHLIVVAFLVAVVY 196 red-crested turaco
XP_003123986 149 -YGEpdYDWTASPR--------D-EESNE----ALEENRSYMEIEQSVRSFKTPPSNVEEEDSHFFFHLIIFAFCIAVIY 214 pig
XP_005001320 147 -YGEadYDWTTSPR--------D-EESDE----ALEENRGYVEIEQSVKSFKSPSSDVEEEDSHFFFHLIIFAFCIAVVY 212 domestic guinea...
KFO26599     129 -YGEpdYDWTTSPR--------D-EESEE----TLEENRGYLEIEQSVKSFQSPASNIEEEDSHFFFHLIIFAFCVAIVY 194 Damara mole-rat
KFW79987     111 dYGP--YEMTPISRyspdlempDdDDSDT----ISNYNEEIKTLDEKIKGVSVSGLE-EEEDSHFFFHLVVVAFLVAVVY 183 golden-collared...
NP_694757    141 -YGEpdYDWTTNPR--------D-EEPEDiniaISKESRRFRGFQDSVEVVKLPPPN--REDSHFFFHLLIFAFCAAVVY 208 house mouse

KFV12611     197 VTYHNKRKIFLLVQSRRWRDGLCSRTVEYHRLDQNVNEAMPSLKITNDYVF 247 red-crested turaco
XP_003123986 215 VTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF 265 pig
XP_005001320 213 VTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVHEAMPSLKITNDYIF 263 domestic guinea pig
KFO26599     195 VMYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVHEAMPSLKITNDYIF 245 Damara mole-rat
KFW79987     184 VTYHNKRKLFLLVQSRRWRDGLCSRTVEYHRLDQNVNEAMPSLKITNDYVF 234 golden-collared manakin
NP_694757    209 VTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF 259 house mouse
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