3OL2,3NVQ,1OLZ


Conserved Protein Domain Family
PSI

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pfam01437: PSI (this model, PSSM-Id:307546 is obsolete and has been replaced by 396154)
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Plexin repeat
A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas shows 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).
Statistics
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PSSM-Id: 307546
Aligned: 95 rows
Threshold Bit Score: 29.6234
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3OL2_B  465 SCAQH--LDCAS-CLAhrdPYCGWCVLLGRCSR-RSEC-SRGQGPEQWLWSFQPel---gCL 518  human
Q1MT68  501 ECGRY--QTCLD-CVLardPHCGWDLDTEHCAT-INSIhRTRSSTVIQSLNDGDas---qCP 555  zebrafish
O95754  512 NCGRL--QSCSE-CILaqdPVCAWSFRLDECVAh-----AGEHRGLVQDIESADvs--slCP 563  human
Q26972  485 HCASK--TRCKD-CVElqdPHCAWDAKQNLCVS-IDTV--TSYRFLIQDVVRGDdn---kCW 537  confused flour beetle
Q8BKG8  514 RCERY--GSCKKsCIAsrdPYCGWLSQGV-CERvTLGMlPGGYEQDTEYGNTAHlg---dCH 569  house mouse
Q17330  496 NCAQQ--TSCSK-CVQlqdPHCAWDSSIARCVH------GGSWTGDQFIQNMVFgqs-eqCP 547  Caenorhabditis elegans
Q24322  496 RCHNDkiTSCSE-CVAlqdPYCAWDKIAGKCRSh----gAPRWLEENYFYQNVAtgqhaaCP 552  fruit fly
Q5VV63  715 ICNKL--TSCKS-CSLn--LNCQWDQRQQECQAl-----PAHLCGEGWSHIGDA------CL 760  human
Q5VV63  666 RCYRY--ADCAS-CTAn-tNGCQWCD-DKKCISaNSNC------------SMSVkny-tkCH 709  human
Q8MJ16  689 RCDQL--TDCYS-CTAn-tNGCQWC--NDHCVPtNHSCtEGQISIFKYDH----------CP 734  cattle
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