Conserved Protein Domain Family
SMG1
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pfam15785: SMG1 (this model, PSSM-Id:292413 is obsolete and has been replaced by 464869)
Serine/threonine-protein kinase smg-1
SMG1 is a family of eukaryotic proteins. In humans this family acts as an mRNA-surveillance protein. In C.elegans, SMG1, a phosphatidylinositol kinase-related protein kinase, is a key regulator of growth. Loss of SMG1 leads to hyperactive responses to injury and subsequent growth that continues out of control. It has an antagonistic role to mTOR signalling in these worms and possibly also in higher eukaryotes.
Links
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Statistics
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PSSM-Id: 292413
Aligned: 13 rows
Threshold Bit Score: 773.903
Created: 1-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q29I80        480 MYACQPSILKLLISNCRAQDLCLWARYPTTHQALLGLLVVHCQANHNFRTNSIL-----------FRDPGLS-TENTSPT 547  Drosophila ps...
XP_001599615  747 MWALKPSILELLAVKLRPHDPLLSVESPLLQYHILFLLFTHCSRYNHFVPSSSLitgtsscrpldIFPGTLE-VPTVSPT 825  jewel wasp
XP_011156509  734 MWALKPSILELVAVKLKPYDNTLSMASPFLQYNVLYLLYAHCSRYNHFVPSSSLitgttacrpmdMFPGTLD-VPATSPA 812  red fire ant
XP_002106336  581 MYACKPSILELLLTNCRAHELKLWGRYPAAQQAIFSLLVVHCQANHNFRTNSSL-----------LRDQELS-AENTSPT 648  Drosophila si...
XP_011454765  614 MWALSPSIFDLASKHFSPLDEVVSEVYPAVQYALLNTLYSHCSRHGNFVSSSSLimq------ttRLDGSLM-ANVNPTT 686  Pacific oyster
XP_006565799  734 MWALKPSILELLAVKLKPYDSNLSSTSPFLQYSILYLLYAHCSRYNHFVPSSSLitgttacrpidMFPGALD-VPTTSPT 812  honey bee
XP_001963716  557 MYACKPSILELLLTNCRAQDLALWSRYPSTHQAIINLLVVHCQANHNFRTNSSL-----------LRDQEQPlSENTSPT 625  Drosophila an...
XP_002067384  603 MYACKPSILELLIRNCRADDLALWSRYPGTYEAILNLLATHCQANHNFRTTSSL-----------LRDGNIQnPEHTSPT 671  Drosophila wi...
XP_009297729  622 MWALSPTVFALLSQNLVIVHSDLAVHHPAVQYAVLYTLYSHCTRHDHFISSSLSsss------psLFDGAVI-STVTTAT 694  zebrafish
XP_414907     630 MWALSPTVFALLSKNLMIVHGDIAVHFPAVQYAVLYTLYSHCSRHDHFISSSLSsss------psLFDGAVI-STVTTAT 702  chicken
XP_001947123  600 MWALQPSIFELLSTKL---DPTIIKMNDPLRFSLMFLLYSHCKKHNNFVASSRLvta------grTSEKSQQnVEINSHK 670  pea aphid
XP_011604331  615 MWALSPTVFTLLSQNLLLVHSDLAVYYPTIQYAVLYTLYSHCTRHDHFISS-SLsss------psLFDGAVI-STVTTAT 686  torafugu
XP_011471375  460 MWALSPTVFALLTHNLTVVHSGLAVCYPAVQYAVLYSLYSHCTRHDHFISSSLSsss------psLFDGAVI-STVTTAT 532  Japanese medaka

Q29I80        548 AHSFEYIIRFLDSILTKAgR-LAAENLKLLLQWTQL---L---LTECRERAPLLLEQDGFLGICYSVGGAAAKWR---PL 617  Drosophila ps...
XP_001599615  826 SGHLSIILNLIAKTIENK-R-APDQTLLLLLDWIQE---I---YLQAENYIGVLSKTEECQTVVSSLLVCGATTNhkvSM 897  jewel wasp
XP_011156509  813 SGHLSIILNLIAKTYNK--N-TPACTLLLLSTWLQE---I---CVQSEKYIGILSETQECQSIISSLINCGATTNddvAN 883  red fire ant
XP_002106336  649 ANNFASILRFLDSVLGQA-HqLTPQNLRVLLQWVEM---L---LRECREKSDLLMEQENFRGICCNIAATASKLT---PV 718  Drosophila si...
XP_011454765  687 ANNFTQILRLLAGLLSQV-H-ASYDSRCLGLKWIAD---I----IGSLQTNPQIFYSEEFTNVIRYITQLGHNSDfqiSM 757  Pacific oyster
XP_006565799  813 SGHLSIILNLIAKSYN-E-Y-TPEQTLLLLSTWMQE---I---CVQAENYIGILSKTKEYENVLASLISCGATLDrdiSI 883  honey bee
XP_001963716  626 ANNFATILRFLAAVLENAgL-LNPQNLRQLLQWLQV---L---LNECRDRCDLLLDQEQFLSICRSLVTTACKWS---PQ 695  Drosophila an...
XP_002067384  672 AQSFETIIGFLARNLEHSlQ-LTQQNLKLLLRWTHS---L---LDECRERASTLLEQPDFMSICRSVAQIATKWG---LL 741  Drosophila wi...
XP_009297729  695 KRHFSTLLNLLGMLLSKD-H-LNPEARRLLLTWSLE---ValmMKKSETYAP-LFSLPSFLKFCKGLLANSLNEDttiCL 768  zebrafish
XP_414907     703 KKHFSIILNLLGLLLKKD-N-LTQDTRKLLMTWALEvavL---MKKSETYAP-LFSLPSFHKFCKGLLANTLLEDvniCL 776  chicken
XP_001947123  671 SGNLVKILNIFEKYLKR--N-VNVDCKLLVLKWIYE---Ll-mHADSASYLNIILLSPEMINIVRSLIYVALKRNeilLF 743  pea aphid
XP_011604331  687 KKHFSTLLGLLGGLLLKE-H-LYIETRRLLLTWAQE---IsvlMKKSDTYSP-LFSLTTFNKFCRGLLANALNEDqsiCL 760  torafugu
XP_011471375  533 KKHFSTLLSLLGGLLSKE-H-LQPEARRLLLTWAQE---IsllMVKSDTYSP-LFSLPSFHKFCRGLLDNALHEDngvSL 606  Japanese medaka

Q29I80        618 ESAACMQAVLDFGPQAlhTK--QDLLVLYRDTALQQLQ-VLTTSGHAPYAQIYAQLPLHMTLFESGLQG-----RRVCVW 689  Drosophila ps...
XP_001599615  898 AVCKNIESLLKAKQVS--WS--EEIYSNIVDLATLHLT-SLDKTVRETYGHLLMNIPLNIVIPKLNKAGllsddKKFRNI 972  jewel wasp
XP_011156509  884 AACNLLEMLMTAKNVV--WK--QETYSSIVDLATLHLT-SCNKTIREKYGALLMCMPINIVIPKLNKQYlfsdtKKVREI 958  red fire ant
XP_002106336  719 ESAACIQTVLDYGLER--LAkyPQLLILYRDTALQQLQ-MVSTNCHAPYFQIYAQLPLHLTLTGCESLMpgmtsRRVSVW 795  Drosophila si...
XP_011454765  758 SVCRCLQDVYKINSNL--P---INLIQSAVKLSVYKLS-DVRPEVRDGYLSLLRVLPANVTTRLYSLLHlggdnDQSISV 831  Pacific oyster
XP_006565799  884 AVCDLFEILLNAKNVT--WK--EEMYVSVVDLVILHLT-SRDEIVRDKYGSLLTQVPLNIVIPKFNKECllsetKKYQGF 958  honey bee
XP_001963716  696 ESAACIQIVLDYGPEK--QEhlLELLTLYRDMALQQLQ-VLSPNGHTPFSQIYAKLPLRITLTGGDTPIpgmssRRVCVW 772  Drosophila an...
XP_002067384  742 EAAACIQSVLGYGLTS--QQ--DPLLLLYRDAALQQIKwILASNQLTVFAQIYAQLPLHVTLFAGgv-----psPRICLW 812  Drosophila wi...
XP_009297729  769 QACNSLQVLSSSLT--------MELLQRCVDVCRVQLV-HSAVRVRQAFGKLLRSVPMHVALSA---------------- 823  zebrafish
XP_414907     777 QACSSLHALSSSLP--------DDLLQRCVDVCRVQLV-HSGARVRQTFGKLLKSIPLDVVLS----------------- 830  chicken
XP_001947123  744 DGIAQILNIVLGNPTF--CQskPLIVVDILDLCLSCIN-LTEHDISKQFYALIHKISLITVLQNVSICSlknksKFNKKI 820  pea aphid
XP_011604331  761 QTCHCIMVLSSSLSTE--LL--Q----SCVDVCRVQLV-NSAVRVRQAYGKLLKTIPLDVALS----------------- 814  torafugu
XP_011471375  607 HSCLS----LQLLLPW--LS--SELLQRCVDVCRVQLV-HSTVRVRQAFAKLFRTIPLDVALS----------------- 660  Japanese medaka

Q29I80        690 QQKMSQcsAV----------------RDNVFQQFVDHLQRPE---Q-EQltqcLRELFVRSYQVAPPDER-------QEK 742  Drosophila ps...
XP_001599615  973 QNYSCE--SLilaqrlhm-rsnngemQAQHFKTYMAFLLQEYyfdA-FG----LSEVFTLCWPTISDNET-------MAK 1037 jewel wasp
XP_011156509  959 VIYSTE--SLilaqrlhmrgnnngelLAQHFKTYMAFLLQEHyldA-SG----LSEMFTLCWPAVPENGT-------TAR 1024 red fire ant
XP_002106336  796 QQRISQwsAV----------------RDTVFRDFFERVQKPE---Q-ESlvhcLRELFVRSCQVAPQDER-------QMN 848  Drosophila si...
XP_011454765  832 QEGAEGvtAAwlarrahinripngefHAVNFRQIMAYILHDTspiQ-SGswnwLEAMFYSC-QDATHDHKmi----eTFR 905  Pacific oyster
XP_006565799  959 KSYSTE--SLilaqrlhmrgtntgemQAQHFKTYMAFLLQEQyldA-SE----LSEIFTLCWPIVSENDT-------TKK 1024 honey bee
XP_001963716  773 QQRMSQcsAV----------------RDSVFRDFFERLQHPE---Q-QPltnsLRDLFVRSCQVAPQDER-------QEK 825  Drosophila an...
XP_002067384  813 QQKISQcsSV----------------RDTVFREFFEHLQ--Qs-eQ-QQlnqsLRDLFVRSCQISAMDER-------QEM 865  Drosophila wi...
XP_009297729  824 -HSHSEikEIslairrhmskvpsntfHPQDFSDLIGFILYGTv-hR-GGkepwLERLYHSCQRLEKKDS---------AM 891  zebrafish
XP_414907     831 NRNHTEiqEIslairshmskapsntfHPQDFSDVISFILYGSt-hR-TGkdnwLERLFYSCQRLDKRDQP-------T-- 899  chicken
XP_001947123  821 NQMMSShmrrk----------avvtlKTEYFKNYMCEMIEPNt-nNnDStthwLLDVVNSCSFDIDSGET---------E 880  pea aphid
XP_011604331  815 VQSQPRmkDIslavrhhmsrapsstfHPQDFSDLISFILYGTl-hR-GGkdpwLERLYYSCQRFEKLDGRgcadsgkPGV 892  torafugu
XP_011471375  661 NHSVPEtrHIslaighlmsrahsttfHPQDFSDLISFILYGVl-hR-GGkdpwLERLYHSCQRLERRDCRggsdssrLDL 738  Japanese medaka

Q29I80        743 LSQCTRRCQRLSAAWLQFEAARYCVDQRLRTTLGKPQETFLGFEAVIMRHARLLSGCAkevERSSL----DGL--SLEQL 816  Drosophila ps...
XP_001599615 1038 MYELALANRTFLFFWGGFEAAQHCVLNKLRTPLGKPQETFTTIEGALKTLAREISCTA---EIPKK----DKR--GLDYL 1108 jewel wasp
XP_011156509 1025 MYDLALANCSFLFFWSGFEAAQHCVLNKLRTSLGKPQDTFTSIESALKILAREISCHSngvEKDVV----RKErqGLDRI 1100 red fire ant
XP_002106336  849 LSQCTKRCQRLATAWLQFEAARYCVEQRLRTTLGKPQDTFFGFEAIIMRHARLLSGCAkemERSAM----DTL--SLEEL 922  Drosophila si...
XP_011454765  906 MSNFVDNNEAMLWFWATWESAQYCVLNRLRTPLGKPQETFTSIEGVLKMFAKELDKPAeerNDISKtdqkKGG--AKSSD 983  Pacific oyster
XP_006565799 1025 MYRLALANRSFLYFWAGFEAAQHCVTNKLRTPLGKPQETFTSIESALKTLAREISY-----SFEAT----KKEkrSLDHL 1095 honey bee
XP_001963716  826 LSQCTRRCQRLATAWMQFEAARYCVDQRLRTTLGKPQETFLGFEAIIMRHARQLSGCGkeeERAAL----DTL--TLEEL 899  Drosophila an...
XP_002067384  866 LSHCIRRCQRLAAAWMQFEAARYCVDQKLRTTLGKPQDTFLGFEAIIMRHARMLSGCAkeaERIDP----DGL--SLMQL 939  Drosophila wi...
XP_009297729  892 VPRALLKTEAVLWQWAVWEAAQFTVLSKLRTPLGRAQDTFQTIEGMIRSLAAHSLNTEqelSQWSG-----GE--SDEGH 964  zebrafish
XP_414907     900 IPRNLLKTDAVLWQWAVWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDqdvSQW-T----TAD--NDEGH 972  chicken
XP_001947123  881 LLSHAQHCRVFLYFWINWEAANFCVINRLRTPFGKPNSTFRAIEGGIKMWARDSISALnd----eT----KVK--HTEGK 950  pea aphid
XP_011604331  893 VPQALLKNEAVLWQWAAWEAAQFTVLSKLRTPLGRAPDTFQTIEGMIRSLAAHAVNPEqdvGAWAG----SGG--DGDGH 966  torafugu
XP_011471375  739 VPWALLKTEAVLWQWAVWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRNLAAYCLNPEqdlGAWAG----SGG--DGDGH 812  Japanese medaka

Q29I80        817 SAIQVNLGMLLGFLDALEKLIYNAAEGSAFALRPPEKPVAAFFRLNNPTCQSWFNRIRIGVVITAMHIQQPELVIRYAQQ 896  Drosophila ps...
XP_001599615 1109 LHEHTRVRQLVEFLEHLERVIHNAAEGCAVALLPHSKPVRTFFHTNRSTCKEWLNRIRLALCVVSLHAGLATNALRNGQR 1188 jewel wasp
XP_011156509 1101 LHEHTRVRLLIEFLEHLERVIHNAADGCAMALLPLSKPVRTFFHTNKSTCKEWLNRIRLALCVVSLHSGLATSALRNGQR 1180 red fire ant
XP_002106336  923 LNMQSNLSLLLGFLDVLEKLIYNAAEGSAFALRPPPKPVAAFFRLNNPTCQSWFNRIRIGVVIIAMHVQQPELVIRYAQQ 1002 Drosophila si...
XP_011454765  984 LSSHLRVHLLLQFMEHLEKLLYNAYEGCAVSMPMSPKTVRTFFRTNKGTCLEWLSRVRSSVIKIALHSGMPAMAIRQCHQ 1063 Pacific oyster
XP_006565799 1096 LSEHTRVRLFIEFLEHLERVIHNAAEGCAIALLPLSKPVRTFFHTNKSTCKEWLNRIRLALCVVSLHSGLASSALRNSQK 1175 honey bee
XP_001963716  900 SNMQSNLVLMLGFLDALEKLIYNAAEGSAFALRPPEKPVAAFFRLNNPTCQSWFNRIRIGVVIIAVHVQQPELVIRYAQK 979  Drosophila an...
XP_002067384  940 SNMQMNLNMLLGFLDALEKLIYNAAEGTAFALRAPEKPVSAFFRLNNPTCQSWFNRIRIGVVIIAMHSQQPELVIRYAQQ 1019 Drosophila wi...
XP_009297729  965 HTNQLRLALLLQFLENLEKLMYNAYEGCASALTAPPKGIRTFFYTNRQTCQDWLTRIRLALMRVGLLSGQPAVTVRHGFD 1044 zebrafish
XP_414907     973 SSNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFD 1052 chicken
XP_001947123  951 LNNLRYTRNLVAFIECLEKSVCNAIDGTATALPTAQKPVRHFFHTNRNTCYEWNSTIRSAMLAVALNSGLSSSAIRHGQY 1030 pea aphid
XP_011604331  967 HSNQLRLALLLQYLENLEKLMYNAYEGCANALTSPPKSIKTFFYTNRQTCQDWLTRIRLALMRVGLLSGKPAVTIRHGFD 1046 torafugu
XP_011471375  813 HSNQLRLTLLLQYLENLEKLMYNAYEGCANALTAPPKAIRTFFYTNRQTCQDWLTRIRLALMRVGLLSGQPAVTVRHGFD 892  Japanese medaka

Q29I80        897 ILV-----TQKTQDATYSQALVYLAWAWISCQEADSLRGLYVWARAKs-SsgKSYQWLQHAAEQAAGRREAALSGYQNVL 970  Drosophila ps...
XP_001599615 1189 LLEdl-ctANNTQGAEFERATLCTARAMVMLGEAEALQGLYVYCKEK--D--RKFVWLKAAMEEAAGKYELAAENYRRIL 1263 jewel wasp
XP_011156509 1181 LLEdl-snADNTQGIEFERATLWTAQAMVALGEAEALQGLYVYTKNK--D--RQFSWLKAAMEEAAGRYESAVDAYKQMI 1255 red fire ant
XP_002106336 1003 ILV-----NPQTQDPTYSQAIVYMAWALISCQESDSLRGLRLWASSKs-S--KSYKWLKYAADQAAGKRESALAGYKTIL 1074 Drosophila si...
XP_011454765 1064 LLQem-kdNNTLQGYDFEQTVLFLVKALVELKEGDAIMGVYNWCKEQt-G--KKFLWIKALVEKATGKYESAAKELKNVL 1139 Pacific oyster
XP_006565799 1176 LLEdl-snSDNIQGIEFERATLCTAQAMVMLGEAEALQGLYVYTKEK--E--RKFPWLKAAMEEAANRYESAAEAYKLII 1250 honey bee
XP_001963716  980 ILL-----TQKAQDATYSQAIVYLAWAWVCCQESDSLRGLYLWARSKs-S--KSFQWLQCAADQAGGRKDAALAGYRSLL 1051 Drosophila an...
XP_002067384 1020 ILV-----TQNPQDCSFSQAIVYLAWAWICCQEADSLRGLYLWARCKvsG--KTFQWLHCAADQAAGRKETALSGYSQIL 1092 Drosophila wi...
XP_009297729 1045 LLTei--kNSSTQGPEMEVPVTMLVEALCELRCPEAIQGLAAWSLANt-G--KSMGWLSSVALQAEGKFEKAALEYQEQL 1119 zebrafish
XP_414907    1053 LLTemktnNSLSQGNELEVTIMMLVEALCELHCPEAIQGIAVWSSAVv-G--KSLTWINSVAQQAEGRFEKATAEYQEHL 1129 chicken
XP_001947123 1031 LVHhl-tkQSEFPVKEFILAIIQLAWAYSKLKESDCIRGLYVWSKEVa-H--LKLPFLNILADQASGKFEEAAESYMNLL 1106 pea aphid
XP_011604331 1047 LLTef--kNSSAQGPEVEVLLTLLAEALCELNCPEAIQGLAAWSLLTs-G--RSLGWLSSVALQAEGRFEKAALEYQDHL 1121 torafugu
XP_011471375  893 LLAef-rsSSS-QALELEVPLALMVEALCELRCPEAIQGLAAWSLQTc-G--KSLGWVSSVALQAEGRFEKAALEYQDQL 967  Japanese medaka

Q29I80        971 AEegqrqel--------------------------------------ephthqF-------------------------- 986  Drosophila ps...
XP_001599615 1264 EDqiltrskddskale-----------------------irckneggdsqvavF-------------------------- 1294 jewel wasp
XP_011156509 1256 DEhvrvkatsddecggggg-----------------sgsgrsarlesdnqvlgF-------------------------- 1292 red fire ant
XP_002106336 1075 AEkeqqsel--------------------------------------ephtrqF-------------------------- 1090 Drosophila si...
XP_011454765 1140 KVmvssdsekadsprddlskvemimpk-kitgilskqspfpppdsnipvlkvhF-------------------------- 1192 Pacific oyster
XP_006565799 1251 EE---------------------------------------------------Hirivnnrsgrdidheeege-dltdgi 1278 honey bee
XP_001963716 1052 NEteeqppe-------------------------------------ldthtrqF-------------------------- 1068 Drosophila an...
XP_002067384 1093 AEddaele----------------------------------------phtrqF-------------------------- 1106 Drosophila wi...
XP_009297729 1120 CAvtgmdcsikvfdrsllkltgtntsspkhtssgegrktvllkssecspevlnF-------------------------- 1173 zebrafish
XP_414907    1130 CA---------------------------------------------------Mtgvdccisgfdktvlklansnsvnna 1158 chicken
XP_001947123 1107 TTnsdqiiiylkgggg-----------------------sinniegplevlqkF-------------------------- 1137 pea aphid
XP_011604331 1122 SAvtgmdcsikssdcflpkfsnstssp-khvnngdnkktvllkgnecssevinF-------------------------- 1174 torafugu
XP_011471375  968 SAitgmdcsirtspscllklsssvssp-khsssgesrktvllksaecspevinF-------------------------- 1020 Japanese medaka

Q29I80        987 -------------VLAQMMQC---------------LQDTGQ--------------------WSQLVDLKQHKLLRPEDk 1018 Drosophila ps...
XP_001599615 1295 -------------CMDHLCKC---------------FRSVGD--------------------WKQLEAWKQREAEILDQ- 1325 jewel wasp
XP_011156509 1293 -------------CMQRLSNC---------------YKAVSD--------------------WSGLVEWKSRENEMLRQ- 1323 red fire ant
XP_002106336 1091 -------------VVAQMMQC---------------LQDLGQ--------------------WSQLVELKQQHMMRPEDr 1122 Drosophila si...
XP_011454765 1193 -------------VVTEIFDC---------------YEKLYD--------------------WESVMEWQENVLQYRQDy 1224 Pacific oyster
XP_006565799 1279 stncadgtsgneeVSDGKNKC---------------FKSEGDnqvlgfcmqrlshcyeavsdWSQLEAWKLQEAEILGR- 1342 honey bee
XP_001963716 1069 -------------VVAQMMQC---------------LQDTGQ--------------------WSQLVELKQRQLTRPEDs 1100 Drosophila an...
XP_002067384 1107 -------------VIAQKMQC---------------LQDLGR--------------------WSRLVELKQKHLNRPEDs 1138 Drosophila wi...
XP_009297729 1174 -------------LANKACEC---------------YVALSD--------------------WESVQEWQASMMNLKKNs 1205 zebrafish
XP_414907    1159 spkhslngetrktVLTKPSDCspevinylgnkacecYISIAD--------------------WSAVQEWQNMVHDLKKSt 1218 chicken
XP_001947123 1138 -------------IIEQLKEC---------------YMSICD--------------------WKPLMDWSQNEENLIPSi 1169 pea aphid
XP_011604331 1175 -------------LVNKASQC---------------YVALCD--------------------WASVKEWQTTVHTLKQNs 1206 torafugu
XP_011471375 1021 -------------LANKACQC---------------YMALCD--------------------WSSVKEWQATVNTLKQNs 1052 Japanese medaka

Q29I80       1019 --eLNSFLQCRNVD---V---SA----FERLLARTES-N 1044 Drosophila pseudoobscura
XP_001599615 1326 ---DKNLCLRRQML---EniaPQ----QATCLRKFEEaE 1354 jewel wasp
XP_011156509 1324 ---DSHAVLRRQMMeniV---QQ----QADCLKKFEKgE 1352 red fire ant
XP_002106336 1123 --eLNPFLQRSNVE---V---NA----LERLLARGQEaC 1149 Drosophila simulans
XP_011454765 1225 shlQAAFNSDVDL---------N----YIRALSAFEDgD 1250 Pacific oyster
XP_006565799 1343 ---DKSAILKKQLI---I---ENntsrQAKCLKKFENsE 1372 honey bee
XP_001963716 1101 --eRNPFLQQSNVE---V---SA----LERLLAKSEEqS 1127 Drosophila ananassae
XP_002067384 1139 --eLNPFLQRSNVE---V---SA----LEKLLAKseels 1165 Drosophila willistoni
XP_009297729 1206 --sSSSVNLKTDF---------N----YIRAMSRFEEgD 1229 zebrafish
XP_414907    1219 --sNTSINLKADF---------N----YIKSLSSFESgE 1242 chicken
XP_001947123 1170 a-kDKYFWQNRYVS-------AN----DLQIVNDVEEgN 1196 pea aphid
XP_011604331 1207 s-iSGSINLRTDL---------N----YIQALSRFEEgD 1231 torafugu
XP_011471375 1053 t-nPVSITLRTDL---------N----YIRALSCFEDgD 1077 Japanese medaka
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