Conserved Protein Domain Family
SSXRD

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pfam09514: SSXRD (this model, PSSM-Id:286586 is obsolete and has been replaced by 430657)
SSXRD motif
SSX1 can repress transcription, and this has been attributed to a putative Kruppel associated box (KRAB) repression domain at the N-terminus. However, from the analysis of these deletion constructs further repression activity was found at the C-terminus of SSX1. Which has been called the SSXRD (SSX Repression Domain). The potent repression exerted by full-length SSX1 appears to localize to this region.
Statistics
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PSSM-Id: 286586
Aligned: 17 rows
Threshold Bit Score: 31.1817
Created: 27-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q96EQ9       171 LRKKNVEVKMYRLRERK-GLAYEEVSEPQDDD 201 house mouse
Q9NQW5       171 LRRKETEGKMYSLRERK-GHAYKEISEPQDDD 201 human
ELK10079      98 LRRKGVEVKMYSLRERT-GRVYQEVSEPQDDD 128 black flying fox
BAF56182     425 GPKRGKHAWTHRLRERKqLVIYEEISDPEEDD 456 human
XP_008249365 171 LRRKNIEVKMYSFRKRK-SQAYKECSEPQDDD 201 rabbit
XP_012028276 148 LGRKETDMKRYSLRERK-GHVYQEVSEPQDDD 178 mouflon
ELW61807     190 VRRKETKVKMYSLRERK-CGTYKEVHEPQDDD 220 Chinese tree shrew
XP_006943762 168 GSKKRKNIWANRLRQRKnLIAYEEISDPEEDD 199 domestic cat
XP_012666716 127 eKKKGKSVWAHRLRERKnFIIYEEISDPEEED 158 small-eared galago
XP_011963164 326 SERKKVDVWANRLRKRQ-PVAYEEISDSEEES 356 sheep
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