Conserved Protein Domain Family
Gly_transf_sug
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pfam04488: Gly_transf_sug (this model, PSSM-Id:282357 is obsolete and has been replaced by 398274)
Glycosyltransferase sugar-binding region containing DXD motif
The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases.
Links
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Statistics
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PSSM-Id: 282357
Aligned: 22 rows
Threshold Bit Score: 70.8199
Created: 26-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O80440       110 GKREMLAVESVF-KAHPQ---GCLMIVSGSLDslqgdsilkplndrgykvfaATPDMSLLLEN-T-PaksWFQeMKSckr 183 thale cress
O14084        78 PERWSNTVNSCR-RQHPDengWQFILWTDEKI------------------------MSFMNEN-Y-S---WFMpVFH--- 124 Schizosaccharom...
Q10323        71 PEKWVGAQKSCI-DLHPD---YEYVLWTDESM------------------------REFIATD-Y-P---WFLtQYD--- 114 Schizosaccharom...
Q9UT67        96 PEGWKGAQQSCI-DLHPD---YEYILWTDEMS------------------------RNFIADN-Y-P---WFLpYFD--- 139 Schizosaccharom...
Q9CLU0        75 PVYCNYLFNRLL-SLSYD---YRYVSTEARAD--------------------------YLKTHaD-E---RTFnAYS--- 117 Pasteurella mul...
Q9UTR6       155 DREVMKYTRFWR-INHPS---YSHAVLDDEQS--------------------KALVISSFGDSsV-S---KISqAYA--- 203 Schizosaccharom...
AJW25589      69 PEHWKEGRQKCL-DLHPD---YKYILWTDEMA------------------------YEFIKEE-Y-P---WFLdTFE--- 112 Saccharomyces c...
EDZ71169     144 PERVQDIKGMWE-SKNPG---FAHEVLNHDVI--------------------NALVHHYFYS--I-P---EILeTYE--- 190 Saccharomyces c...
AJR76571     114 PSSFRTYQKTWSgSYSPD---YQYSLISDDSI---------------------IPFLENLYAP-V-P---IVIqAFK--- 161 Saccharomyces c...
WP_000049394  70 PVYLNYLFNRLM-SLNCD---YRYVSTEARG--------------------------EFLKEH-TsP---EVYdAYS--- 112 Vibrio cholerae

O80440       184 dpgRIPLHQNLSNLARLAFLYKYGGVYLDTDFIVTRSFkglkNSIGAQTVVE 235 thale cress
O14084       125 ---SYPYNIQKFDAARYFILYHYGGVYMDLDIGCKKPM----DPLLSKATFI 169 Schizosaccharomyces pombe 972h-
Q10323       115 ---SYPYNIERADVVRYFILYKYGGIYLDLDVGCNRTL----DPLL-HYPAW 158 Schizosaccharomyces pombe 972h-
Q9UT67       140 ---AYPFNVQRADVIRYFVLYHYGGNYIDLDDGCRQRL----DSLL-YYPVW 183 Schizosaccharomyces pombe 972h-
Q9CLU0       118 ---KLTDGAAQADFWRIFTLYHEGGIYMDIDGHLVWCL----DSIIDEEDSE 162 Pasteurella multocida
Q9UTR6       204 ---MMPLPVLKADFFRYLVLLAKGGIYSDIDTAPLKHI----NNWIPREYRK 248 Schizosaccharomyces pombe 972h-
AJW25589     113 ---NYKYPIERADAIRYFILSHYGGVYIDLDDGCERKL----DPLLAFPAFL 157 Saccharomyces cerevisiae YJM693
EDZ71169     191 ---ALPSIILKIDFFKYLILLVHGGVYADIDTFPVQPI----PNWIPEELSP 235 Saccharomyces cerevisiae AWRI1631
AJR76571     162 ---LMPGNILKADFLRYLLLFARGGIYSDMDTMLLKPI----DSWPSQNKSW 206 Saccharomyces cerevisiae YJM193
WP_000049394 113 ---RLTNGAAQADLWRLVVLNTYGGVYMDIDATLVWPL----DKLLGDSQel 157 Vibrio cholerae
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