Conserved Protein Domain Family
Keratin_B2
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pfam01500: Keratin_B2 (this model, PSSM-Id:279797 is obsolete and has been replaced by 366678)
Keratin, high sulfur B2 protein
High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibers in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.
Links
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Statistics
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PSSM-Id: 279797
Aligned: 8 rows
Threshold Bit Score: 89.0729
Created: 18-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O70148   1 M--ACCATSFCGFPTCSTGGTCGSNCCQPSCSQssccq--------------------------pscsqSSCCQPSCTQS 52  Norway rat
P08131   1 M--ACCSTSFCGFPTCSTGGTCGSNFCQPTCCQ------------------------------------TSCCQPTSIQT 42  sheep
P02440   1 M--ACCSTSFCGFPICSTAGTCG----------------------------------------------SSCCRSTCSQT 32  sheep
Q07627   1 M--ACCQTSFCGFPSCSTSGTCG----------------------------------------------SSCCQPSCCET 32  human
Q8IUG1   1 M--TCCQTSFCGYPSCSTSGTCGSSCCQPSCCEtsccqpsccetsccqpsccqtsfcgfpsfstsgtcsSSCCQPSCCET 78  human
P02443   1 Tg-SCCG------PTFSSLS-CGGGCLQPCCYRd-----------------------------------PCCCRPVSSTQ 37  sheep
Q28707   1 MvnSCCG------SVCSERG-CGQDFCQE----------------------------------------ESCCRPSCCRP 33  rabbit
P02438   1 M--ACCSTSFCGFPICSTGGTCGSSPCQPTCCQ------------------------------------TSCCQPTSIQT 42  sheep

O70148  53 SCCQPTCSQSSCCQPTcsq----------------sscCQPsCCQTSCCQPTCCQNSSCQTSC---CGTGSGQEGGSGAT 113 Norway rat
P08131  43 SCCQPTSIQTSCCQPTsiq----------------tscCQPiSIQTSCCQPTCLQTSGCETGCgigGSIGYGQVGSSGAV 106 sheep
P02440  33 SCCQPT------------------------------------SIQTSCCQPTCLQTSGCETGCgigGSTGYGQVGSSGAV 76  sheep
Q07627  33 SSCQPRCCETSCCQPSccqtsfcgfpsfstggtcdsscCQPsCCETSCCQPSCYQTSSCGTGCgigGGIGYGQEGSSGAV 112 human
Q8IUG1  79 S----------------------------------------------CCQPSCCQTSSCGTGCgigGGIGYGQEGSSGAV 112 human
P02443  38 TVSRPVTFVSRCTRPI----------------------CEP------CRRPVCCDPCSLQEGC----------------- 72  sheep
Q28707  34 QCCQP-----SCCRPTcci----------------sscCRPqCCQSVCCQPTCCRPSCYISSC----------------- 75  rabbit
P02438  43 SCCQPISIQTSCCQPT--------------------------SIQTSCCQPTCLQTSGCETGCgigGSIGYGQVGSSGAV 96  sheep

O70148 114 SCRVRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCGQSCCRPAC-------CCHcceps-cskpsCSE 185 Norway rat
P08131 107 SSRTKWCRPDCRVEGTSLPPCCVVSCTSPSCCQLYYAQASCCRPSYCGQSCCRPAC-------CCQptciepvceptCCE 179 sheep
P02440  77 SSRTRWCRPDCRVEGTSLPPCCVVSCTSPSCCQLYYAQASCCRPSYCGQSCCRPAC-------CCQptctepvceptCSQ 149 sheep
Q07627 113 STRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVC-------CCY-----------CSE 174 human
Q8IUG1 113 STRIRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAEASCCRPSYCGQSCCRPVC-------CCY-----------SCE 174 human
P02443  73 ------CRPITCCPTSCQAVVCRPCCWATTCCQPVSVQCPCCRPTSC-PSAPRTTCrtfrtspC---------------- 129 sheep
Q28707  76 ------CRPTCCRPTCCRPTCCRPTSCQTTCCRT-----QCCRPSCCVSTCCRPCCss---gsC---------------- 125 rabbit
P02438  97 SSRTRWCRPDCRVEGTSLPPCCVVSCTPPSCCQLYYAQASCCRPSYCGQSCCRPAC-------CCQptciepicepsCCE 169 sheep

O70148 186 PSC 188 Norway rat
P08131 180 PTC 182 sheep
P02440 150 PIC 152 sheep
Q07627 175 PTC 177 human
Q8IUG1 175 PTC 177 human
P02443 130 --C 130 sheep
Q28707 126 --C 126 rabbit
P02438 170 PTC 172 sheep
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