3BIX_C          4 QKLDdvdpl---------vttnfGKIRGIKKELNNeIlGPVIQFLGVPYAAPPTGEHRFQPPEP-PSPWSDIRNATQFAP 73   Norway rat
Q9VPZ5         38 GGKQskappvddpvifarlfdrdARVEGFRNPSTG-----IYSFLGMHYAEPPVGPLRYSRPVY-KRLAGD-FNATKHGP 110  fruit fly
Q8T016         26 AQQThik-------------leqGDLIGLKVFPDG-TrGAVYAFLGIPYAQAPINELRFAPAKP-SSSFNRTLQATTMQP 90   fruit fly
O44089         21 AKIRitngvie-----greltatYSLYG---NQTS-V-----VFLGIPHIEPPVGKLRFRKPKPyRNTWNNTLETKEFKP 86   Caenorhabditi...
P25726         18 SASDpadpll--------vdlpnGKLRG----RDN-G--NYYSYESLPYAEPPVGDLRFEAPQPyKQQWTDTFDATQPPV 82   Drosophila ps...
Q9VP25         35 DASEtatvtv-------elyngqGTVLGNYAYTAW-TdRAFMQFRGIPFAEPPIEELRFRPPVA-RSPWTGTLNALNFGQ 105  fruit fly
P33438         51 ETRYaqpqeav------vqapevGQILGISGHKTI-AnRPVNAFLGIRYGTVGGGLARFQAAQP-I-GYQGRVNATVQSP 121  fruit fly
Q9VLJ2         19 VESRvrgrqydeekdtivelptlGSIQGKILETAW-TkREVLQFVDVRYAEPPTGLHRFKAPRP-IEPWEDVMDATAEKI 96   fruit fly
Q9VLJ1         75 VFTttv--------------pdlGRLRGRTLTTDW-TgQKIMQFLDIPYGK-AE---RFRPAEP-APSWKGVLPAHRPHA 134  fruit fly
XP_002084615   18 NASDpddpll--------vqlpqGKLRGR-----D-N-GSYYSYESIPYAEPPTGDLRFEAPEPyKQKWSDIFDATKTPV 82   Drosophila si...

3BIX_C         74 VCPQnIIDGrlpevmlpvwFTNNLDvvssyvqdQSEDCLYLNIYVPTEDdirdsggPKPVMVYIHGGSYMEGTG---NLY 150  Norway rat
Q9VPZ5        111 PCIQpHPQF----------PQRIIG---------DEDCLLLNVYTPQMPde---ttGLPVFVWIHPGGYRYGSAa----Q 164  fruit fly
Q8T016         91 LCPQlANTIyd------esSDGSMPrs----vsTDEDCLYLNIWTPESGmr---ygKLPIVVIVTGEEFAYDWP---RNR 154  fruit fly
O44089         87 TCFRnFV-A----------ADGST----------SEDCLYINVYSNKYCie---nkNCSVMVVVPSGLVQSHGSffnDTI 142  Caenorhabditi...
P25726         83 LCMQwDQFIq--------gDDKLAG---------NEDCLTVSVYKPKNSsr----nSFPVVAQIHGGAFMFGGA---SQN 138  Drosophila ps...
Q9VP25        106 RCPViTNLd---------sQMSDA---------ELEDCLTLSVYT-KNLsa-----sQPVMFYIYGGGFYNGSS----ED 157  fruit fly
P33438        122 NCAQfPELDrl-------rLSESRGe-------NVDDCLTLDIYAPEGAn------qLPVLVFVHGEMLFDGGS----EE 177  fruit fly
Q9VLJ2         97 GCPS-VVsmds-----lrrLDDVLD---------VEDCLTMTITTP-NVts-----rLPVLVYIHGEYLYEGS----NSE 151  fruit fly
Q9VLJ1        135 GCPSiQDLIvfa----kleEDGFD----------VEDCLRLSVNTKAMEgk-----sLPVMVYIHGDFFYDGDS----VE 191  fruit fly
XP_002084615   83 ACLQwDQFTp--------gANKLVG---------EEDCLTVSIYKPKNSkr----ssFPVVAHIHGGAFMFGAA---WQN 138  Drosophila si...

3BIX_C        151 DGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAK---GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNL 227  Norway rat
Q9VPZ5        165 YDATPMAQRGAIVVAPQYRLGSLGIM--GDGTKQf-dGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMY 241  fruit fly
Q8T016        155 INGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHrn-vpGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLAL 233  fruit fly
O44089        143 INNFVGQNRNIVVVTVPYRLGIFGSPNLPGNVKnileKNLMLYDVIEGCNWVDREIGNFGGDSSKITYFGHRSGATIGAI 222  Caenorhabditi...
P25726        139 GHENFMREGNLILVKISYRLGPLGFVSTGDADLS---GNFGLKDQRLALLWIKQNIASFGGEPENILVIGHSAGGGSVHL 215  Drosophila ps...
Q9VP25        158 HPPNYLLEKDVVLVVPQYRVGALGWLSTYTEELP---GNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASS 234  fruit fly
P33438        178 AQPDYVLEKDVLLVSINYRLAPFGFLSALTDELP---GNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHA 254  fruit fly
Q9VLJ2        152 APPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIP---GNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHL 228  fruit fly
Q9VLJ1        192 AAPGYLLEHDVVLVSVRYRLGPFGFLSTLTDEMP---GNAAVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGAALVNV 268  fruit fly
XP_002084615  139 GHENVMREGKFILVKISYRLGPLGFASTGDRDLP---GNYGLKDQRLALKWIKQNIASFGGEPQNVLLIGHSAGGASVHL 215  Drosophila si...

3BIX_C        228 LTLShy-seKGLFQRAIAQSGTALSSWAVSFQP--AKYARILATKVGC-NVSDtv-------eLVECLQKKPYKELVDQD 296  Norway rat
Q9VPZ5        242 LSMSptsrsAGDVHGVVAMSGTALSQYAMDKEP--VQSVQEVAKINGC-PTGNel-------eIVNCLRSKSAEDIIKND 311  fruit fly
Q8T016        234 VATLed--sSQVKQLVLMSPGPIMRALGQNHQKwiVETGQVLVQKLGC-QFEEaqr-----rqLMGCLRRKSREDLLRAY 305  fruit fly
O44089        223 LSLLpe--sENLFHQMILMST-PLYMQSKTANS---KSFLKVVKQVGC-DESIen------vdIIECMRKVRAENFVDTH 289  Caenorhabditi...
P25726        216 QVLRed--fSKLAKAAISFSGNALDPWVVQQGG--RGRAFELGRIVGC-GQASds------vtLKKCLKSKPASEIVSAV 284  Drosophila ps...
Q9VP25        235 LLLSpk-tgDNMFKRAIVQSGSIFASWAINKDP--KAQSRRICIQLGC-SGCEqh------dqLVKCIQKAKVIDILKAT 304  fruit fly
P33438        255 LSLSgr--aGNLFQQLILQSGTALNPYLIDNQP--LDTLSTFARLARC-PPPSinpsaqglkpLYDCLARLPTSQLVAAF 329  fruit fly
Q9VLJ2        229 LTLSpv-vqRGLFHQVIYHSGSAIMPIFLEEDP--RKHAQEIAKKADC-KMVTvr-------dLNTCLMELTALELLTAF 297  fruit fly
Q9VLJ1        269 LTLSpa-vpAGLFHRVIYQSGTALSPAFITDAP--LGATKAIGRIAGC-KQSTkv------dqLNKCLNRLNATMLLAAF 338  fruit fly
XP_002084615  216 QMLRed--fGQLAKAAFSFSGNALDPWVVQKGA--RGRAFELGRTVGCeSAEDsa-------sLKKCLKSKSASELVTAV 284  Drosophila si...

3BIX_C        297 V--Q--PARYHIAFG-----------P---VIDGD--------VIPDDPQILMEQGEflNYDIML-GVNQGEGLKFVENI 349  Norway rat
Q9VPZ5        312 DkvQ--TERLAGRALvkgltgnvgfqP---HIESEddgralpsLIVGEPEQQLKSSNfsGIPLLT-GVTKHETANSVTVE 385  fruit fly
Q8T016        306 E--S--VYNHGNGSS----------------QLGV--------ILPEGLPLEQRLRNktLPPVLL-GITSNEGAFLQDYW 356  fruit fly
O44089        290 N--Q--LNEENEDSLn-------------fVIDGV--------LLRDEPRRILESGNfkKIPLLI-GTVPHEVLYTRYMI 343  Caenorhabditi...
P25726        285 RnfL--VFAYVPFTPf---------gP---VVESPdap---eaFISQHPVDIIKSGKfaQVPWAV-TYTTEDGGYNAALL 346  Drosophila ps...
Q9VP25        305 AseS--FSPIVGDLH----------------GILP--------QQPSELVKSYRR----QIPILT-GFTQHDGSFVLASY 353  fruit fly
P33438        330 Eq-L--LLQNEHLGLtqlg----gfkL---VVGDPl------gFLPSHPASLATNSSl-ALPMII-GATKDASAFIVSRI 391  fruit fly
Q9VLJ2        298 Me-H--ALEKSDLGIghtg----giqF---TIGGPs------gVLPKHPYDLMLEt---NFSYPAmGGCPKNAGSRVLNE 358  fruit fly
Q9VLJ1        339 S--V--HGENQPSLSgga------ygGvqlVIGGPs------gILPEHPGRLLAAEKfqAYPTMG-GSVKHGGTFMLRDI 401  fruit fly
XP_002084615  285 R--KflVFSYVPFAPf---------sP---VLEPSdap---daFLTQDPREVIKSGKfgQVPWAV-SYVTEDGGYNAALL 346  Drosophila si...

3BIX_C        350 VD-SDDG---Vsasd-----------------fdfAVSNFVDNLYGYPE----GKD-----VLRETIKFMYTDWADRhNP 399  Norway rat
Q9VPZ5        386 TI-EKVFg--SaeqflgslsdslnkltsflkidklTGQIAKPELPGLTS----VL--------TPTLQDVWKVPQALnVD 450  fruit fly
Q8T016        357 LD-VAREgqvAlhkyi---------------nhtlLPNVMRALES-VGE----ESS-----TQLAAIRWRYFNG-KG-EG 408  fruit fly
O44089        344 DK-ENGI---Kmke------------------lleLCELFGFVGAYEKP----YG-------FVEQCVEFYMKN------ 384  Caenorhabditi...
P25726        347 LE-KQASsgrElivd----------------lndrWFDWAPYLLFYRDS----MTTikdmdDYSRKLRQEYLGD-RR-FS 403  Drosophila ps...
Q9VP25        354 YD-ALAAkvaNvssl----------------svrqFSQGINDLVNDTSG----LTD-----NILNRLLFKPQALNSHdHS 407  fruit fly
P33438        392 YD-QLARl-qSrnvsd--------------yidvvLRHTAPPSEHRLWK--------------QWALREIFTPIQEQtAS 441  fruit fly
Q9VLJ2        359 IV-DNDFe-gKipdd----------------eyntYNYIDHVIRQTVGT----DKTmlltsFVTHDFFNRNLME-NGtFD 415  fruit fly
Q9VLJ1        402 FA-DIFN---Etild----------------dtmtGRQYIDTIIEQANG----ADPsgswkEFSDEEIFTQNDVKNGtFK 457  fruit fly
XP_002084615  347 LKeRKSG---Ividd----------------lndrWLELAPYFLFYRDTktkkDMD-----DYSRKIKEDYLGNQK--FD 400  Drosophila si...

3BIX_C        400 ETRR-KTLLALFTDHQWVAP-A-VATADLHSNFGSPT-YFYAFYHHCQ--------TDQVPAWADAAHGDEVPYVLGIPM 467  Norway rat
Q9VPZ5        451 QVL--SKVVESTTDVLFNLP---AVLTTQVWSRLAPA-FMYSFEYNGTkskginflKGLPIVSET---AHDKPETVGHGD 521  fruit fly
Q8T016        409 VSHLlAGMQRLLSESLYELP---YSRILELLNGTTS--YAYVFDHSHSmd-----mRGRRNLFGGASHSSDLPLLLGPSL 478  fruit fly
O44089        385 --S--TTAT-FLDDYIFHVPtS-YLARKHSSEKPVY--LFVNYGAPYGde-----wSKLNPKIMK-YYDIDFNDKYEMAG 450  Caenorhabditi...
P25726        404 VESY-WDLQRLFTDVLFKNStE-ISLDLHRKHGKSPV-YAFVYDNPANtgigqglaKRTDINFGT-VHGDDYFLIFENIV 479  Drosophila ps...
Q9VP25        408 AAV--SSYFDLTTNIFMKSPvI-TLATKMYTQQRSTPvYVYSFEYEGTy-------TRFGYEFGN-SHYPFNGGVHHSND 476  fruit fly
P33438        442 LQTVaPGLLELSNYILYRAP---VINSISQSYRSVPA-YLYTFDYRGEhhrfghlsNPLPFGVDA-SLSDDSVYLFPYPP 516  fruit fly
Q9VLJ2        416 TLI--PRLIDVAGTLNHKLPvL-LALNMNNKHNPDNT-FLYSFDYAGEf---------NRYKEM--DEETNLQSPFKAGV 480  fruit fly
Q9VLJ1        458 RLT--PGLIDLCSTISLKNPvL-LVLQANAKKLPNST-YLYSFDYEGE---------QNRYATGE-DEANFVPFDMGVSL 523  fruit fly
XP_002084615  401 IESY-SELQRLFTDILFKNS-TqESLDLHRKYGKSPA-YAYVYDNPAEkgiaqvlaNRTDYDFGTV-HGDDYFLIFEN-F 475  Drosophila si...

3BIX_C        468 IGPTELfpc------------nfSKNDVMLs-AVVMTYWTNFAKTGDPnqpvpqdtkfihtkPNR-FEEVAWTRYSQKdq 533  Norway rat
Q9VPZ5        522 EIGYMFdandifgnpmeetrltsAEDLKVR--NNLIDLLVKFANKDKE--------------EGG--KSSIFQSVTG--- 580  fruit fly
Q8T016        479 FQQIARrr--------------fSGEEEQLc-RKIRGAFANFIKNGNP---------------TPgRIYDGWLPYNKE-- 526  fruit fly
O44089        451 MRYGFHek--------------sFEFWDDT--AKEYGGVFTFSND-QP---------------KSfDTFPVWEFAKL--- 495  Caenorhabditi...
P25726        480 REPQLR-----------------SDEEIIS--RNFLKMLNDFVLSENG---------------TLaFGTCVFQDNVGS-- 523  Drosophila ps...
Q9VP25        477 NIYLFAth--------------pLEGQDTQmsQKMVDVWTSFAIEGVP---------------------RNLSPLSSAsg 521  fruit fly
P33438        517 EASRLN-----------------PLDRSLS--RALVTMWVNFATTGVP---------------NP--SSGVWPQATSEy- 559  fruit fly
Q9VLJ2        481 SLTDEAlylfpyp---ehvtrlsRPDQSMA--HRMVELWTNFVISGNP---------------LGsARVGYWPPMTTLyg 540  fruit fly
Q9VLJ1        524 TDDNLYlfpwpr------flalnSNRDLKv-aRRMVALWTSFATTGVP----------------QaPGLPAWPAMNDEt- 579  fruit fly
XP_002084615  476 VREVEM-----------------RPDEEIIs-RNFINMLADFASSDNG---------------DLkYGECAFKNNVGSe- 521  Drosophila si...

3BIX_C        534 -lyLHIGLKPRVKEHYRANK-VNLW 556  Norway rat
Q9VPZ5        581 ---KATPFIKIDTKLQTSND---FR 599  fruit fly
Q8T016        527 ---NPFVYSLGEQAKTPQTGsVDEA 548  fruit fly
O44089        496 ---KNYVKTGSGAHKIPKEI-EKFI 516  Caenorhabditis elegans
P25726        524 ---SKLQLLSITRNGCENLE-LESF 544  Drosophila pseudoobscura pseudoobscura
Q9VP25        522 pynKLNLEVTKGDDLLDTLT--AAI 544  fruit fly
P33438        560 ---GPFLRFTNNQQSPLELDp-HFG 580  fruit fly
Q9VLJ2        541 -pyMRIDDTMTIGGNYFTEF--SAT 562  fruit fly
Q9VLJ1        580 ---GPYMKIDRTVSFGDNYL-DEYR 600  fruit fly
XP_002084615  522 ----kFQLLAIYIDGCQNRQhvefp 542  Drosophila simulans