Conserved Protein Domain Family
OASL_repeat1

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cd01811: OASL_repeat1 (this model, PSSM-Id:176406 is obsolete and has been replaced by 340509)
2'-5' oligoadenylate synthetase-like protein, repeat 1 of 2
OASL_repeat1 (2'-5' oligoadenylate synthetase-like protein) belongs to a family of interferon-induced 2'-5' oligoadenylate synthetases which are important for the antiviral activity of interferons. While each member of this famliy has a conserved N-terminal OAS catalytic domain, only OASL has two tandem ubiquitin-like repeats located at the C-terminus and this CD represents one of those repeats.
Statistics
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PSSM-Id: 176406
Aligned: 4 rows
Threshold Bit Score: 151.506
Created: 8-May-2010
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_222236 351 VQVTVKQTGREEWILLTNPHSPIRKLKAKIKKRMNLCGELRISFQEPGGERQPLSGRKTLSDYGIFSKVNIRVMETFPPE 430 Norway rat
NP_003724 354 IHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSE 433 human
BAB26655  355 VQVRVKQTGTVDWTLWTNPYSPIRKMKAEIRREKNFGGELRISFQEPGGERQLLSSRKTLADYGIFSKVNIQVLETFPPE 434 house mouse
XP_543430 398 IQVTVEQWGYSDLILRVNPYKPIKKIQEKMWQSRCCSGLQHLYLQELGAKQQLLSSQYSLADYGVFSNTRICLVETNSHE 477 dog
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