3DI2


Conserved Protein Domain Family
IL7
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smart00127: IL7 
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Interleukin-7 and interleukin-9 family.
IL-7 is a cytokine that acts as a growth factor for early lymphoid cells of both B- and T-cell lineages. IL-9 is a multifunctional cytokine that, although originally described as a T-cell growth factor, its function in T-cell response remains unclear.
Links
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Statistics
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PSSM-Id: 128432
Aligned: 6 rows
Threshold Bit Score: 234.562
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3DI2_A         4 CDIEGKDGKQYESVLMVSIDQLlDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLK 83  human
NP_001009777  27 CDFSGKDGGAYQNVLMVSIDDL-DNMINFDSNCLNNEPNFFKKHSCDDNKEASFLNRAARKLKQFLKMNISDDFKLHLST 105 sheep
P26895        27 CDISGKDGGAYQNVLMVNIDDL-DNMINFDSNCLNNEPNFFKKHSCDDNKEASFLNRASRKLRQFLKMNISDDFKLHLST 105 cattle
NP_032397     27 CHIKDKEGKAYESVLMISIDEL-DKMTGTDSNCPNNEPNFFRKHVCDDTKEAAFLNRAARKLKQFLKMNISEEFNVHLLT 105 house mouse
P56478        27 CHIKDKDGKAFGSVLMISINQL-DKMTGTDSDCPNNEPNFFKKHLCDDTKEAAFLNRAARKLRQFLKMNISEEFNDHLLR 105 Norway rat
AAX36840      27 CDIEGKDGKQYESVLMVSIDQLlDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLK 106 synthetic const...

3DI2_A        84 VSEGTTILLNCTGQVKGRKPAALGAAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMG 150 human
NP_001009777 106 VSQGTLTLLNCTSKGKGRKPPSLGEAQPTKNLEENKSLKEQRKQNDLCFLKILLQKIKTCWNKILRG 172 sheep
P26895       106 VSQGTLTLLNCTSKGKGRKPPSLSEAQPTKNLEENKSSKEQKKQNDLCFLKILLQKIKTCWNKILRG 172 cattle
NP_032397    106 VSQGTQTLVNCTSK-------------------EEKNVKEQKK-NDACFLKRLLREIKTCWNKILKG 152 house mouse
P56478       106 VSDGTQTLVNCTSK-------------------EEKTIKEQKK-NDPCFLKRLLREIKTCWNKILKG 152 Norway rat
AAX36840     107 VSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMG 173 synthetic construct
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