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    Cep85l centrosomal protein 85-like [ Mus musculus (house mouse) ]

    Gene ID: 100038725, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Cep85lprovided by MGI
    Official Full Name
    centrosomal protein 85-likeprovided by MGI
    Primary source
    MGI:MGI:3642684
    See related
    Ensembl:ENSMUSG00000038594 AllianceGenome:MGI:3642684
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm9766; 1700003O08Rik
    Summary
    Predicted to be involved in neuron migration. Predicted to be located in pericentriolar material. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in lissencephaly 10. Orthologous to human CEP85L (centrosomal protein 85 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 10.2), lung adult (RPKM 1.5) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    10 B3; 10
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (53149537..53256765, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (53273441..53379883, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40649 Neighboring gene STARR-seq mESC enhancer starr_26690 Neighboring gene predicted gene, 36173 Neighboring gene predicted gene, 19395 Neighboring gene transaldolase 1 pseudogene Neighboring gene phospholamban Neighboring gene STARR-seq mESC enhancer starr_26692 Neighboring gene predicted gene, 36229 Neighboring gene STARR-seq mESC enhancer starr_26693 Neighboring gene transmembrane protein 229B, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics. Voisinne G, et al. Nat Immunol, 2019 Nov. PMID 31591574, Free PMC Article
    2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Hein MY, et al. Cell, 2015 Oct 22. PMID 26496610
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in neuron migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in pericentriolar material ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    centrosomal protein of 85 kDa-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204983.2 → NP_001191912.1  centrosomal protein of 85 kDa-like

      See identical proteins and their annotated locations for NP_001191912.1

      Status: VALIDATED

      Source sequence(s)
      AC105169, AC153524
      Consensus CDS
      CCDS56701.1
      UniProtKB/Swiss-Prot
      A0A1W2P884
      Related
      ENSMUSP00000151909.2, ENSMUST00000220443.2
      Conserved Domains (1) summary
      COG1196
      Location:442 → 742
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      53149537..53256765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512494.5 → XP_006512557.1  centrosomal protein of 85 kDa-like isoform X2

      UniProtKB/TrEMBL
      E9QA61
      Related
      ENSMUSP00000152032.2, ENSMUST00000220376.2
      Conserved Domains (1) summary
      COG1196
      Location:340 → 640
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_036155444.1 → XP_036011337.1  centrosomal protein of 85 kDa-like isoform X1

      Conserved Domains (1) summary
      COG1196
      Location:430 → 730
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    3. XM_017313744.3 → XP_017169233.1  centrosomal protein of 85 kDa-like isoform X2

      UniProtKB/TrEMBL
      E9QA61
      Related
      ENSMUSP00000093356.7, ENSMUST00000095691.7
      Conserved Domains (1) summary
      COG1196
      Location:340 → 640
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    4. XM_017313743.3 → XP_017169232.1  centrosomal protein of 85 kDa-like isoform X2

      UniProtKB/TrEMBL
      E9QA61
      Conserved Domains (1) summary
      COG1196
      Location:340 → 640
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A1W2P884.1 GenPept UniProtKB/Swiss-Prot:A0A1W2P884

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
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