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    UBE2D2 ubiquitin conjugating enzyme E2 D2 [ Bos taurus (cattle) ]

    Gene ID: 541003, updated on 6-Jun-2024

    Summary

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    Official Symbol
    UBE2D2provided by VGNC
    Official Full Name
    ubiquitin conjugating enzyme E2 D2provided by VGNC
    Primary source
    VGNC:VGNC:36580
    See related
    BGD:BT26841; Ensembl:ENSBTAG00000004161
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See UBE2D2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (50789407..50832731)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene endothelial cell surface expressed chemotaxis and apoptosis regulator Neighboring gene small integral membrane protein 33 Neighboring gene stimulator of interferon response cGAMP interactor 1 Neighboring gene uncharacterized LOC132345752 Neighboring gene CXXC finger protein 5 Neighboring gene uncharacterized LOC112447430

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC138112

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme E2 D2
    Names
    (E3-independent) E2 ubiquitin-conjugating enzyme D2
    E2 ubiquitin-conjugating enzyme D2
    ubiquitin carrier protein D2
    ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
    ubiquitin-protein ligase D2
    NP_001039961.1
    XP_024850309.1
    XP_059744335.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046496.1 → NP_001039961.1  ubiquitin-conjugating enzyme E2 D2

      See identical proteins and their annotated locations for NP_001039961.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114654
      UniProtKB/Swiss-Prot
      Q1RMX2
      UniProtKB/TrEMBL
      A0AAA9S092
      Related
      ENSBTAP00000049292.1, ENSBTAT00000055723.2
      Conserved Domains (1) summary
      cl00154
      Location:1 → 146
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50789407..50832731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059888352.1 → XP_059744335.1  ubiquitin-conjugating enzyme E2 D2 isoform X2

    2. XM_024994541.1 → XP_024850309.1  ubiquitin-conjugating enzyme E2 D2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S092
      Conserved Domains (1) summary
      cl00154
      Location:12 → 150
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1RMX2.1 GenPept UniProtKB/Swiss-Prot:Q1RMX2

    Gene LinkOut

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