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    Gpr119 G-protein coupled receptor 119 [ Mus musculus (house mouse) ]

    Gene ID: 236781, updated on 12-May-2024

    Summary

    Official Symbol
    Gpr119provided by MGI
    Official Full Name
    G-protein coupled receptor 119provided by MGI
    Primary source
    MGI:MGI:2668412
    See related
    Ensembl:ENSMUSG00000051209 AllianceGenome:MGI:2668412
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Enables phosphatidylcholine binding activity. Acts upstream of or within insulin secretion. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in cytoplasm and plasma membrane. Is expressed in colon and ileum. Orthologous to human GPR119 (G protein-coupled receptor 119). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Gpr119 in Genome Data Viewer
    Location:
    X A5; X 25.69 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (47756856..47763355, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (48667979..48674478, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene zinc finger protein 280C Neighboring gene solute carrier family 25 (mitochondrial carrier, brain), member 14 Neighboring gene STARR-seq mESC enhancer starr_47124 Neighboring gene RNA binding motif protein, X-linked 2 Neighboring gene hyaluronic acid binding protein 4 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylcholine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylcholine binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of receptor complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    glucose-dependent insulinotropic receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181751.2NP_861416.1  glucose-dependent insulinotropic receptor

      See identical proteins and their annotated locations for NP_861416.1

      Status: VALIDATED

      Source sequence(s)
      AB233291
      Consensus CDS
      CCDS30113.1
      UniProtKB/Swiss-Prot
      Q2ABS2, Q7TQP3
      Related
      ENSMUSP00000060591.4, ENSMUST00000053970.4
      Conserved Domains (1) summary
      pfam00001
      Location:42279
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      47756856..47763355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)