7DVQ: Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)

PDB ID: 7DVQDownload
MMDB ID: 200424
PDB Deposition Date: 2021/1/14
Updated in MMDB: 2021/04
Experimental Method:
electron microscopy
Resolution: 2.89  Å
Source Organism:
Similar Structures:
Biological Unit for 7DVQ: 49-meric; determined by author
Molecular Components in 7DVQ
Label Count Molecule
Proteins (45 molecules)
1
Pre-mrna-processing-splicing Factor 8
Molecule annotation
1
116 KDA U5 Small Nuclear Ribonucleoprotein Component
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 200 KDA Helicase
Molecule annotation
1
U5 Small Nuclear Ribonucleoprotein 40 KDA Protein
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D3
Molecule annotation
2
Small Nuclear Ribonucleoprotein-associated Proteins B and B'
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D1
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D2
Molecule annotation
2
Small Nuclear Ribonucleoprotein F
Molecule annotation
2
Small Nuclear Ribonucleoprotein E
Molecule annotation
2
Small Nuclear Ribonucleoprotein G
Molecule annotation
1
Sodium Channel Modifier 1
Molecule annotation
1
Splicing Factor 3B Subunit 1
Molecule annotation
1
Splicing Factor 3B Subunit 2
Molecule annotation
1
Splicing Factor 3B Subunit 3
Molecule annotation
1
Splicing Factor 3B Subunit 4
Molecule annotation
1
Splicing Factor 3B Subunit 6
Molecule annotation
1
PHD Finger-like Domain-containing Protein 5A
Molecule annotation
1
Splicing Factor 3B Subunit 5
Molecule annotation
1
Cell Division Cycle 5-like Protein
Molecule annotation
1
Crooked Neck-like Protein 1
Molecule annotation
1
Spliceosome-associated Protein Cwc15 Homolog
Molecule annotation
1
SNW Domain-containing Protein 1
Molecule annotation
1
Pleiotropic Regulator 1
Molecule annotation
1
Smad Nuclear-interacting Protein 1
Molecule annotation
1
RNA-binding Motif Protein, X-linked 2
Molecule annotation
1
Bud13 Homolog
Molecule annotation
1
Ring-type E3 Ubiquitin-protein Ligase Ppil2
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase Cwc27 Homolog
Molecule annotation
1
Pre-mrna-splicing Factor Atp-dependent RNA Helicase Dhx16
Molecule annotation
1
G-patch Domain and KOW Motifs-containing Protein
Molecule annotation
1
Ring Finger Protein 113a
Molecule annotation
1
Serine/arginine Repetitive Matrix Protein 2
Molecule annotation
1
Pre-mrna-splicing Factor Cwc22 Homolog
Molecule annotation
1
Serine/arginine Repetitive Matrix Protein 1
Molecule annotation
1
Cysteine-rich Pdz-binding Protein
Molecule annotation
1
RNA-binding Protein 48
Molecule annotation
1
Armadillo Repeat-containing Protein 7
Molecule annotation
Nucleotides(4 molecules)
1
U5 Snrna
Molecule annotation
1
U6atac Snrna
Molecule annotation
1
Pre-mrna
Molecule annotation
1
U12 Snrna
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
1
INOSITOL HEXAKISPHOSPHATEINOSITOL HEXAKISPHOSPHATE
2
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
3
5
MAGNESIUM IONMAGNESIUM ION
4
2
POTASSIUM IONPOTASSIUM ION
5
1
5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine
6
7
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303