Abstract
Limb Expression 1 (Lix1), a founding member of a novel gene family, was identified in a screen for genes transiently and locally expressed during early chicken limb development. Most prominently, Lix1 is transiently expressed in the nascent hindlimb bud between Hamburger-Hamilton stages 15 and 19. Chicken Lix1 transcripts are also found in the basal plate of rhombomeres 3 and 5, in pharyngeal and in foregut mesenchyme and in all facial primordia except for the mandibular arches. Homologs of chick Lix1 exist in human, mouse and Drosophila.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Autophagy-Related Proteins
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Chick Embryo
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Cloning, Molecular
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Drosophila
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Expressed Sequence Tags
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Face / embryology
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Hindlimb / embryology
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Humans
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Mesoderm / metabolism
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Mice
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Molecular Sequence Data
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Protein Biosynthesis*
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Protein Structure, Tertiary
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Proteins*
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RNA, Messenger / metabolism
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Sequence Homology, Amino Acid
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Time Factors
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Tissue Distribution
Substances
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Autophagy-Related Proteins
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Lix1 protein, mouse
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Proteins
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RNA, Messenger
Associated data
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GENBANK/AF351203
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GENBANK/AF351204