Cloning and expression analysis of chicken Lix1, a founding member of a novel gene family

Mech Dev. 2001 Dec;109(2):405-8. doi: 10.1016/s0925-4773(01)00535-4.

Abstract

Limb Expression 1 (Lix1), a founding member of a novel gene family, was identified in a screen for genes transiently and locally expressed during early chicken limb development. Most prominently, Lix1 is transiently expressed in the nascent hindlimb bud between Hamburger-Hamilton stages 15 and 19. Chicken Lix1 transcripts are also found in the basal plate of rhombomeres 3 and 5, in pharyngeal and in foregut mesenchyme and in all facial primordia except for the mandibular arches. Homologs of chick Lix1 exist in human, mouse and Drosophila.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Autophagy-Related Proteins
  • Chick Embryo
  • Cloning, Molecular
  • Drosophila
  • Expressed Sequence Tags
  • Face / embryology
  • Hindlimb / embryology
  • Humans
  • Mesoderm / metabolism
  • Mice
  • Molecular Sequence Data
  • Protein Biosynthesis*
  • Protein Structure, Tertiary
  • Proteins*
  • RNA, Messenger / metabolism
  • Sequence Homology, Amino Acid
  • Time Factors
  • Tissue Distribution

Substances

  • Autophagy-Related Proteins
  • Lix1 protein, mouse
  • Proteins
  • RNA, Messenger

Associated data

  • GENBANK/AF351203
  • GENBANK/AF351204