Myelodysplastic syndrome disorder: bone marrow mesenchymal stromal cells
Summary:
Analysis of bone marrow (BM) mesenchymal stromal cells from adult patients representing MDS subtypes RCMD (refractory cytopenia with multilineage dysplasia) and RAEB (refractory anemia with excess blasts). Results provide insight into molecular changes in the BM microenvironment contributing to MDS.
Kim M, Hwang S, Park K, Kim SY et al. Increased expression of interferon signaling genes in the bone marrow microenvironment of myelodysplastic syndromes. PLoS One 2015;10(3):e0120602. PMID: 25803272