DataSet Record GDS5501: Expression Profiles Data Analysis Tools Sample Subsets
Title: Progranulin deficiency effect on various brain regions: time course
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Summary: Analysis of brain cortices, cerebella, and hippocampi of progranulin (GRN) deficient mutants at ages 2, 6, and 9 months. GRN mutations cause frontotemporal dementia. Results provide insight into the function of GRN in the central nervous system.
Organism: Mus musculus
Platform: GPL6885: Illumina MouseRef-8 v2.0 expression beadchip
Citation:
  • Rosen EY, Wexler EM, Versano R, Coppola G et al. Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron 2011 Sep 22;71(6):1030-42. PMID: 21943601
Reference Series: GSE31840 Sample count: 99
Value type: transformed count Series published: 2011/09/01