Sotrastaurin effect on mantle cell lymphoma cell lines
Summary:
Analysis of various mantle cell lymphoma (MCL) lines treated with sotrastaurin (STN). Jeko-1 and Mino are STN-sensitive cell lines; Z-138 and Maver-1 are STN-insensitive cell lines. STN is a pan-protein kinase C (PKC) inhibitor. Results provide insight into the molecular response to PKC inhibition.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Rahal R, Frick M, Romero R, Korn JM et al. Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma. Nat Med 2014 Jan;20(1):87-92. PMID: 24362935
