Chronic simian immunodeficiency virus infection: colon, jejunum and lung
Summary:
Analysis of colon, jejunum and lung from therapy-naïve, SIV-infected males. Gut and lung mucosa are important entry portals for pathogens and provide innate immune defense against infection. Results provide insight into molecular mechanisms underlying mucosal immune response during SIV infection.
Verhoeven D, George MD, Hu W, Dang AT et al. Enhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection. J Immunol 2014 Apr 1;192(7):3308-18. PMID: 24610016
