Progesterone effect on uteri of ovariectomized, steroid receptor coregulator-2 deficient mutants
Summary:
Analysis of uteri from steroid receptor coregulator-2 (SRC-2) mutants that were ovariectomized at 6 weeks and treated with progesterone (P4) 2 weeks later. SRC-2 is a member of the p160/SRC family of coregulators. Results provide mechanistic insight into SRC-2's role in endometrial decidualization.
Kommagani R, Szwarc MM, Kovanci E, Creighton CJ et al. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod 2014 Apr;90(4):75. PMID: 24571987