Sonic Hedgehog inhibitor cyclopamine effect on co-culture of mesenchymal stem cells and umbilical vein endothelial cells
Summary:
Analysis of a co-culture of 92% human mesenchymal stem cells (hMSC) and 8% human umbilical vein endothelial cells (huvEC) treated with the Sonic Hedgehog morphogen inhibitor cyclopamine. The co-culture of hMSC and huvEC supports the formation of a primitive three dimensional vascular network.
GPL10526:
[HG-U133_Plus_2] Affymetrix GeneChip Human Genome HG-U133 Plus 2 Array [Brainarray HGU133Plus2_Hs_ENTREZG_v12]
Citation:
Rivron NC, Raiss CC, Liu J, Nandakumar A et al. Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation. Proc Natl Acad Sci U S A 2012 Mar 20;109(12):4413-8. PMID: 22388744
