Azoxymethane/dextran sulfate sodium-induced ulcerative colitis-associated colorectal cancer model: time course
Summary:
Temporal analysis of colon from AOM/DSS-induced model of ulcerative colitis-associated colorectal cancer (UC-CRC). Nonresolving inflammation is associated with increased incidence of CRC. Results provide insight into molecular mechanisms underlying the development from colitis to colorectal cancer.
Tang A, Li N, Li X, Yang H et al. Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model. Carcinogenesis 2012 Jul;33(7):1375-83. PMID: 22610167