High fat diet effect on the skeletal muscle: time course
Summary:
Analysis of skeletal muscles of C57BL/6J animals fed a low or high fat diet for 3 or 28 days. Oversupply of lipid to skeletal muscle can result in insulin resistance, a characteristic of metabolic syndrome (MS). Results provide insight into the molecular events underlying the early onset of MS.
de Wilde J, Mohren R, van den Berg S, Boekschoten M et al. Short-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice. Physiol Genomics 2008 Feb 19;32(3):360-9. PMID: 18042831
